List projects.

Fields

id (integer)

Primary key.

Expansions

To activate relation expansion add the desired fields as a comma separated list to the expand query parameter like this:

?expand=<field>,<field>,<field>,...

The following relational fields can be expanded:

  • organization
  • category
  • type
  • partner_function
  • manager
  • contact
  • status
  • grant
  • research
  • event
  • study
  • language
  • program
  • funders

Filters

To filter for exact value matches:

?<fieldname>=<value>

Possible exact filters:

  • organization
  • category
  • manager
  • contact
  • status
  • grant
  • research
  • study
  • language
  • funders
  • program

For advanced filtering use lookups:

?<fieldname>__<lookup>=<value>

All fields with advanced lookups can also be used for exact value matches as described above.

Possible advanced lookups:

  • begin_planned: gt, gte, lt, lte
  • begin_effective: gt, gte, lt, lte
  • end_planned: gt, gte, lt, lte
  • end_effective: gt, gte, lt, lte
GET /v1/research/project/?format=api&offset=980&ordering=begin_effective
HTTP 200 OK
  Allow: GET, HEAD, OPTIONS
  Content-Type: application/json
  Vary: Accept
  
  {
    "count": 2329,
    "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1000&ordering=begin_effective",
    "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=960&ordering=begin_effective",
    "results": [
        {
            "id": 3836,
            "title": {
                "de": "Archaeelle und bakterielle Extremophile an Bord der Internationalen Raumstation ",
                "en": "Archaeal and bacterial extremophiles on board the International Space Station"
            },
            "short": "ARBEX",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-01-01T01:00:00+01:00",
            "end_planned": "2018-12-31T01:00:00+01:00",
            "end_effective": "2018-06-30T02:00:00+02:00",
            "assignment": "2014-12-15T11:23:48+01:00",
            "program": null,
            "subprogram": "FFG-ASAP Einzelprojekt der Grundlagenforschung",
            "organization": 14046,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 90021,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                416
            ],
            "funder_projectcode": "847977",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3836-95317-12",
                "3836-90021-10",
                "3836-91470-12"
            ]
        },
        {
            "id": 3901,
            "title": {
                "de": "Neue Biomarker aus dem Muskel- und Gefäßstoffwechsels für hypertonie Schwangerschaftserkrankungen",
                "en": "New Muscle and Vascular- Biomarker for Hypertensive Pregnancy Diseases"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-02-01T01:00:00+01:00",
            "begin_effective": "2015-01-01T01:00:00+01:00",
            "end_planned": "2017-02-01T01:00:00+01:00",
            "end_effective": "2017-12-31T01:00:00+01:00",
            "assignment": "2015-02-06T10:15:57+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14064,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51978,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3901-80093-12",
                "3901-50909-12",
                "3901-51978-10"
            ]
        },
        {
            "id": 3913,
            "title": {
                "de": "COST: Das Europäische Netzwerk der Photon Upconversion Technologie: von Design der Materialien zu biomedizinischen Applikationen",
                "en": "COST: The European Upconversion Network: From the Design of Photon-upconverting\r\nNanomaterials to (Biomedical) Applications"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-01-01T01:00:00+01:00",
            "end_planned": "2018-12-31T01:00:00+01:00",
            "end_effective": "2018-12-31T01:00:00+01:00",
            "assignment": "2015-02-24T09:46:25+01:00",
            "program": 22,
            "subprogram": null,
            "organization": 17230,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 53900,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3913-53900-10"
            ]
        },
        {
            "id": 3834,
            "title": {
                "de": "Komplexe Schwingungssysteme: Modellierung und Analyse ",
                "en": "Complex Oscillatory Systems: Modelling and Analysis"
            },
            "short": "COSMOS_HORIZON",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-01-01T01:00:00+01:00",
            "end_planned": "2018-12-31T01:00:00+01:00",
            "end_effective": "2019-08-31T02:00:00+02:00",
            "assignment": "2014-12-12T09:24:46+01:00",
            "program": 109,
            "subprogram": "Innovative Training Network /European Joint Doctorate",
            "organization": 14010,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 51671,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                10
            ],
            "funder_projectcode": "642563",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3834-51671-10"
            ]
        },
        {
            "id": 4060,
            "title": {
                "de": "Genetische Basis der sekundär sklerosierenden Cholangitis* nach kritischer Krankheit",
                "en": "Secondary Sclerosing Cholangitis in Critically Ill Patients (SSC-CIP): Possible genetic basis of the disease"
            },
            "short": "SSC Genetik",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-01-01T01:00:00+01:00",
            "end_planned": "2017-12-31T01:00:00+01:00",
            "end_effective": "2019-12-31T01:00:00+01:00",
            "assignment": "2015-07-14T13:53:55+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14081,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50989,
            "contact": null,
            "status": 2,
            "research": 5,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1748
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "4060-62756-12",
                "4060-81091-12",
                "4060-50989-10"
            ]
        },
        {
            "id": 3849,
            "title": {
                "de": "Chronische Elektro-Stimulation zur Therapie altersbedingter Stimmveränderungen.",
                "en": "Chronic electrical stimulation for treatment of age-related voice changes."
            },
            "short": "Altersstimme",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-01-05T01:00:00+01:00",
            "end_planned": "2017-12-21T01:00:00+01:00",
            "end_effective": "2018-07-31T02:00:00+02:00",
            "assignment": "2015-01-08T13:25:58+01:00",
            "program": null,
            "subprogram": "BRIDGE",
            "organization": 14068,
            "category": 10,
            "type": 10,
            "partner_function": 1,
            "manager": 50670,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                416
            ],
            "funder_projectcode": "848458",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3849-50670-10",
                "3849-50698-12",
                "3849-77116-12",
                "3849-88652-12"
            ]
        },
        {
            "id": 3852,
            "title": {
                "de": "Aufklärung der spezifischen Zytotoxizität von Dimethylacrylshikonin in Melanomzellen",
                "en": "Elucidation of specific cytotoxic effects of dimethylacrylshikonin in melanoma cells"
            },
            "short": "SpeDiMel",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-01-28T01:00:00+01:00",
            "end_planned": "2018-01-01T01:00:00+01:00",
            "end_effective": "2019-01-27T01:00:00+01:00",
            "assignment": "2015-01-09T09:19:54+01:00",
            "program": 72,
            "subprogram": null,
            "organization": 17218,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 50826,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "P27505",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3852-50826-10"
            ]
        },
        {
            "id": 3833,
            "title": {
                "de": "Beurteilung der Eignung von SNOMED CT für umfangreiche, EU-weite elektronische Gesundheitsdienste ",
                "en": "Assessing SNOMED CT for Large Scale eHealth Deployments in the EU"
            },
            "short": "ASSESS-CT_Horizon",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-02-01T01:00:00+01:00",
            "end_planned": "2015-12-31T01:00:00+01:00",
            "end_effective": "2016-07-31T02:00:00+02:00",
            "assignment": "2014-12-10T13:15:33+01:00",
            "program": 109,
            "subprogram": "PHC-34 eHealth Interoperability - Topic (iii) SNOMED CT for eHealth deployments\r\n",
            "organization": 14026,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 72306,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                10
            ],
            "funder_projectcode": "643818",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3833-72306-10"
            ]
        },
        {
            "id": 3854,
            "title": {
                "de": "Die Prävalenz von FHH bei PatientInnen mit einem primären Hyperparathyreoidismus",
                "en": "The Prevalence of FHH in Patients with Primary Hyperparathyroidism"
            },
            "short": "EPATH-FHH",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2014-07-01T02:00:00+02:00",
            "begin_effective": "2015-02-01T01:00:00+01:00",
            "end_planned": "2014-02-01T01:00:00+01:00",
            "end_effective": "2019-01-31T01:00:00+01:00",
            "assignment": "2015-01-13T10:13:03+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14083,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 81519,
            "contact": null,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1565
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3854-81519-10"
            ]
        },
        {
            "id": 3912,
            "title": {
                "de": "Die Behandlung und Überwachung von Krebs durch die Identifizierung von zirkulierenden Tumorzellen und zirkulierender Tumor-DNA aus dem Blut",
                "en": "Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood"
            },
            "short": "CANCER-ID",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-02-01T01:00:00+01:00",
            "begin_effective": "2015-02-01T01:00:00+01:00",
            "end_planned": "2020-01-31T01:00:00+01:00",
            "end_effective": "2019-12-31T01:00:00+01:00",
            "assignment": "2015-02-23T14:19:41+01:00",
            "program": 24,
            "subprogram": "11th Call Innovative Medicines Initiative",
            "organization": 14021,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                10
            ],
            "funder_projectcode": "115749",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 3865,
            "title": {
                "de": "Knochen und Fertilität",
                "en": "Bone and Fertility"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-02-01T01:00:00+01:00",
            "begin_effective": "2015-02-01T01:00:00+01:00",
            "end_planned": "2016-01-31T01:00:00+01:00",
            "end_effective": "2023-06-30T02:00:00+02:00",
            "assignment": "2015-01-26T12:41:49+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14080,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51809,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1519
            ],
            "funder_projectcode": "MEFO-11",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 4256,
            "title": {
                "de": "The functional role of HDL in the tumor microenvironment",
                "en": "The functional role of HDL in the tumor microenvironment"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-02-01T01:00:00+01:00",
            "begin_effective": "2015-02-01T01:00:00+01:00",
            "end_planned": "2018-01-31T01:00:00+01:00",
            "end_effective": "2019-01-31T01:00:00+01:00",
            "assignment": "2016-01-28T12:53:45+01:00",
            "program": 69,
            "subprogram": null,
            "organization": 14013,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "J3664-B19",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 3915,
            "title": {
                "de": "Dysregulation von extrazellulärer Matrix in verschiedenen Formen pulmonaler Hypertonie",
                "en": "Extracellular matrix dysregulation in different forms of pulmonary hypertension "
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2014-07-01T02:00:00+02:00",
            "begin_effective": "2015-03-01T01:00:00+01:00",
            "end_planned": "2017-06-30T02:00:00+02:00",
            "end_effective": "2018-12-31T01:00:00+01:00",
            "assignment": "2015-02-26T14:23:51+01:00",
            "program": 79,
            "subprogram": null,
            "organization": 14010,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 82090,
            "contact": null,
            "status": 2,
            "research": 5,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3915-61540-12",
                "3915-82090-10"
            ]
        },
        {
            "id": 3848,
            "title": {
                "de": "Der Darm: Ursache für das erhöhte Infektionsrisiko bei Nierenerkrankung im Endstadium?",
                "en": "The gut: reason for the increased risk of infection in endstage renal disease?"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-03-01T01:00:00+01:00",
            "begin_effective": "2015-03-01T01:00:00+01:00",
            "end_planned": "2015-12-30T01:00:00+01:00",
            "end_effective": "2016-04-30T02:00:00+02:00",
            "assignment": "2015-01-07T14:26:32+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14081,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1519
            ],
            "funder_projectcode": "MEFO-04",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 4241,
            "title": {
                "de": "Analytische Elektronenmikroskopie der Eiseneinlagerungen in den Stammganglien",
                "en": "Analytical Electron Microscopy of Iron Deposits in the Basal Ganglia"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-03-02T01:00:00+01:00",
            "begin_effective": "2015-03-02T01:00:00+01:00",
            "end_planned": "2016-03-02T01:00:00+01:00",
            "end_effective": "2016-03-02T01:00:00+01:00",
            "assignment": "2016-01-21T11:12:01+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14017,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50960,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                530
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "4241-50960-10"
            ]
        },
        {
            "id": 4079,
            "title": {
                "de": "Osteointegration of Polymer Composites for Medical Implants",
                "en": "Osteointegration of Polymer Composites for Medical Implants"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-01-01T01:00:00+01:00",
            "begin_effective": "2015-03-20T01:00:00+01:00",
            "end_planned": "2016-12-31T01:00:00+01:00",
            "end_effective": "2016-12-31T01:00:00+01:00",
            "assignment": "2015-08-18T15:38:09+02:00",
            "program": 65,
            "subprogram": null,
            "organization": 14052,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "M177",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "4079-50696-12",
                "4079-59782-12",
                "4079-61131-12"
            ]
        },
        {
            "id": 3961,
            "title": {
                "de": "Kritische zelluläre Interaktionen für ILC3 Funktionen im humanen Darm",
                "en": "Cell-cell interactions critical to ILC3 function in the human gut"
            },
            "short": "GutILC3",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-04-01T02:00:00+02:00",
            "begin_effective": "2015-04-01T02:00:00+02:00",
            "end_planned": "2017-03-31T02:00:00+02:00",
            "end_effective": "2017-03-31T02:00:00+02:00",
            "assignment": "2015-03-31T16:23:00+02:00",
            "program": 109,
            "subprogram": "H2020-MARIE SKLODOWSKA-CURIE ACTIONS-IF-2014",
            "organization": 14022,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                10
            ],
            "funder_projectcode": "655677",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 3820,
            "title": {
                "de": "Charakterisierung humaner Stimmlippen-Fibroblasten",
                "en": "Characterisation of human vocal fold fibroblasts"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-04-01T02:00:00+02:00",
            "begin_effective": "2015-04-01T02:00:00+02:00",
            "end_planned": "2016-03-31T02:00:00+02:00",
            "end_effective": "2016-03-31T02:00:00+02:00",
            "assignment": "2014-11-27T10:56:31+01:00",
            "program": 69,
            "subprogram": "Host Institution: Karolinska Institutet",
            "organization": 14068,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50670,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "J 3661",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3820-50670-10"
            ]
        },
        {
            "id": 4018,
            "title": {
                "de": "MUGies - Forschen macht schlau",
                "en": "MUGies - Forschen macht schlau"
            },
            "short": "MUGies ",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2015-05-01T02:00:00+02:00",
            "begin_effective": "2015-05-01T02:00:00+02:00",
            "end_planned": "2016-10-31T01:00:00+01:00",
            "end_effective": "2016-10-31T01:00:00+01:00",
            "assignment": "2015-05-21T10:42:08+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14052,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 53237,
            "contact": null,
            "status": 2,
            "research": 5,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                416
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "4018-53237-10"
            ]
        },
        {
            "id": 4243,
            "title": {
                "de": "Synthese licht-aktiver Modulatoren/Marker von TRPC3/6-Kanälen",
                "en": "Synthesis of light-responsive modulators/labels of TRPC3/6-channels"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": "Novel light-responsive modulators/labels of TRPC3/6-channels\r\nMammalian Transient Receptor Potential (TRP) channels include six related protein\r\nfamilies. Members of the human TRP Canonical (TRPC) subfamily\r\n(TRPC1/3/4/5/6/7), form channels that mediate Ca2+- and Na+-ion entry and are\r\nexpressed in many mammalian cell types to serve a broad-range of important\r\nphysiological processes. Recently, TRPC3/6 channels have been implicated in the\r\npathogenesis of cardiovascular disorders including heart failure, arrhythmias, and\r\nsudden death. Consequently, TRPC channels have emerged as highly promising\r\ntargets for drug development, while, at the same time, their exact cellular function and\r\nprinciples of pharmacologic modulation are still incompletely understood and require\r\nbetter understanding. For this, novel strategies to experimentally control channel\r\nfunction are urgently needed. These channels are endogenously controlled by plasma\r\nmembrane lipid metabolites, which are difficult to administer in most experimental\r\nsettings. Novel modulating or blocking ligands with potentially suitable selectivity for\r\nexact experimental control of TRPC3/6 channel have just recently been reported. One\r\nobjective of this proposal is therefore the synthesis of small modulators\r\n(inhibitors/activators) of TRPC3/6-channels that response to light, allowing the\r\ncontrol of biological events with unparalleled spatial and temporal precision – so\r\ncalled “photoswitches” (e.g. azobenzens). Taking advantage of our experience in the\r\nsynthesis of pyrazole-based inhibitors of TRPC3/6-channels and benzimidazolonebased\r\nactivators as well as our expertise in microwave and continuous-flow\r\nchemistry, we aim to generate and explore various photoswitchable ligands in\r\nconnection to the emerging pharmacology of TRPC3/6-channels. Another objective\r\nof ours, involving small photoresponsive molecules, is the synthesis of photoaffinity\r\nlabels to help in the elucidation of potential ligand-binding sites in the TRPC3/6-\r\nchannels as well as on the structure elucidation of TRPC3/6-channels.\r\nThe research proposed herein is meant to become a significant contribution to\r\na thrilling and rapidly growing field for optoregulation of biological functions in\r\nmammalian cells and for better understanding on the TRPC3/6-channel machinery. If\r\npositive results are obtained, the arising pharmacology will importantly aid\r\ninvestigations of the physiological and pathophysiological roles of TRPC channels,\r\nfacilitate the validation of TRPCs as potential therapeutic targets in different\r\nchannelopathies, and possibly provide foundations for drug discovery and\r\ndevelopment."
            },
            "begin_planned": "2015-05-01T02:00:00+02:00",
            "begin_effective": "2015-05-01T02:00:00+02:00",
            "end_planned": "2018-04-30T02:00:00+02:00",
            "end_effective": "2018-12-31T01:00:00+01:00",
            "assignment": "2016-01-22T13:09:43+01:00",
            "program": 72,
            "subprogram": null,
            "organization": 14011,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 78591,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "P 28243-B27   ",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "4243-78591-10"
            ]
        }
    ]
}