Project List
List projects.
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GET /v1/research/project/?format=api&offset=860&ordering=end_planned
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=880&ordering=end_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=840&ordering=end_planned", "results": [ { "id": 3712, "title": { "de": "Domäneninteraktion zur Kontrolle der STIM1 Aktivierung von Orai1 Kanälen", "en": "Domain interactions controlling STIM1 activation of Orai1 channels " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-10-01T02:00:00+02:00", "begin_effective": "2014-10-01T02:00:00+02:00", "end_planned": "2017-10-01T02:00:00+02:00", "end_effective": "2019-03-31T01:00:00+01:00", "assignment": "2014-07-17T13:01:43+02:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 78591, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P27263", "ethics_committee": null, "edudract_number": null, "persons": [ "3712-78591-10" ] }, { "id": 4710, "title": { "de": "Mikrobiom bei Schizophrenie", "en": "Microbiome in Schizophrenia " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-01T02:00:00+02:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2017-10-01T02:00:00+02:00", "end_effective": "2017-10-01T02:00:00+02:00", "assignment": "2016-11-29T12:48:26+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2442, "title": { "de": "CD-Labor für Forschung an biologischen Proben und Biobanktechnologien", "en": "CD-Laboratory for Advanced Biospecimen Research and Biobanking Technologies" }, "short": "CDLabBRBT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-11-01T01:00:00+01:00", "begin_effective": "2010-12-01T01:00:00+01:00", "end_planned": "2017-10-30T01:00:00+01:00", "end_effective": "2017-11-30T01:00:00+01:00", "assignment": "2011-03-03T17:53:09+01:00", "program": 97, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 3, "manager": 51663, "contact": 50828, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 23 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2442-51663-10" ] }, { "id": 3265, "title": { "de": "HOMAGE", "en": "HOMAGE" }, "short": "HOMAGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-11-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2017-10-30T01:00:00+01:00", "end_effective": "2019-01-31T01:00:00+01:00", "assignment": "2013-05-13T17:29:05+02:00", "program": 24, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "305507", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4935, "title": { "de": "EFSD - Albert Renold Travel Fellowship", "en": "EFSD - Albert Renold Travel Fellowship" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-05-01T02:00:00+02:00", "begin_effective": "2017-05-01T02:00:00+02:00", "end_planned": "2017-10-31T01:00:00+01:00", "end_effective": "2017-10-31T01:00:00+01:00", "assignment": "2017-04-25T16:33:52+02:00", "program": 103, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 431 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4716, "title": { "de": "Aktivierung des Tumorsuppressors p53 durch Fasten zur Verlängerung der Lebensspanne", "en": "Activating the tumor suppressor p53 by fasting for life-span extension" }, "short": "p53 and Aging", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-12-01T01:00:00+01:00", "begin_effective": "2016-12-01T01:00:00+01:00", "end_planned": "2017-11-30T01:00:00+01:00", "end_effective": "2017-11-30T01:00:00+01:00", "assignment": "2016-12-01T11:04:59+01:00", "program": null, "subprogram": "Subventionsansuchen an die Stadt Graz Wissenschaft", "organization": 14017, "category": 10, "type": 10, "partner_function": 1, "manager": 89979, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4716-89979-10" ] }, { "id": 4080, "title": { "de": "Die Rolle der microRNA-199a in diffus großzelligen B-Zell Lymphomen", "en": "Elucidating the role of microRNA-199a in diffuse large B cell lymphom" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-12-01T01:00:00+01:00", "begin_effective": "2016-01-01T01:00:00+01:00", "end_planned": "2017-11-30T01:00:00+01:00", "end_effective": "2018-12-31T01:00:00+01:00", "assignment": "2015-08-19T11:24:52+02:00", "program": null, "subprogram": "START - Med Uni Graz", "organization": 14082, "category": 10, "type": 10, "partner_function": 3, "manager": 65239, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4080-59183-12", "4080-65239-10" ] }, { "id": 3828, "title": { "de": "Bakterielle Dysbiose des Kolons als Ursache der Säuglingsproktokolitis\r\n", "en": "Colonic bacterial dysbiosis as a cause of infant proctocolitis" }, "short": "BaktDysFPIP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-12-01T01:00:00+01:00", "begin_effective": "2014-12-01T01:00:00+01:00", "end_planned": "2017-11-30T01:00:00+01:00", "end_effective": "2020-03-31T02:00:00+02:00", "assignment": "2014-12-04T11:21:49+01:00", "program": 108, "subprogram": null, "organization": 14091, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI 450", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3849, "title": { "de": "Chronische Elektro-Stimulation zur Therapie altersbedingter Stimmveränderungen.", "en": "Chronic electrical stimulation for treatment of age-related voice changes." }, "short": "Altersstimme", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-01-01T01:00:00+01:00", "begin_effective": "2015-01-05T01:00:00+01:00", "end_planned": "2017-12-21T01:00:00+01:00", "end_effective": "2018-07-31T02:00:00+02:00", "assignment": "2015-01-08T13:25:58+01:00", "program": null, "subprogram": "BRIDGE", "organization": 14068, "category": 10, "type": 10, "partner_function": 1, "manager": 50670, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "848458", "ethics_committee": null, "edudract_number": null, "persons": [ "3849-50670-10", "3849-50698-12", "3849-77116-12", "3849-88652-12" ] }, { "id": 4112, "title": { "de": "SFB: Mathematische Optimierung mit Anwendungen in der biomedizinischen Forschung\r\n3. Förderperiode", "en": "SFB: Mathematical Optimization and Applications in Biomedical Sciences" }, "short": "MOBIS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-01-01T01:00:00+01:00", "begin_effective": "2015-01-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2018-04-30T02:00:00+02:00", "assignment": "2015-10-05T12:06:36+02:00", "program": 67, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 1, "manager": 50966, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "F32", "ethics_committee": null, "edudract_number": null, "persons": [ "4112-50966-10" ] }, { "id": 4378, "title": { "de": "EULAR Empfehlungen für die Anwendung der Bildgebung in der Diagnose und im Management der Groß Gefäßvaskulitis in der klinischen Praxis", "en": "EULAR recommendations for the use of imaging in the diagnosis and management of large vessel vasculitis in clinical practice " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-07-01T02:00:00+02:00", "begin_effective": "2016-07-01T02:00:00+02:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2016-03-30T16:05:51+02:00", "program": null, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 66227, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4378-66227-10" ] }, { "id": 3738, "title": { "de": "Potentielle positive Effekte von intestinaler ATGL Überexpression", "en": "Potential beneficial effects of intestinal ATGL overexpression" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-01-01T01:00:00+01:00", "begin_effective": "2015-01-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2019-01-31T01:00:00+01:00", "assignment": "2014-08-07T12:28:43+02:00", "program": 72, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 51904, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 27070", "ethics_committee": null, "edudract_number": null, "persons": [ "3738-51904-10" ] }, { "id": 4729, "title": { "de": "ETABLIERUNG EINER NEUEN METHODE ZUR BEURTEILUNG DER DARMWANDBARRIERE", "en": "ESTABLISHING A NEW METHOD FOR FUNCTIONAL ANALYSIS OF THE GUT BARRIER" }, "short": "Darmwand SAXS", "url": null, "abstract": { "de": "Hintergrund: Die Darmwand stellt eine essentielle Barriere des Körpers gegen Invasion von Bakterien und bakteriellen Toxinen dar. Verschiedene Erkrankungen wie Sepsis, Tumorkachexie, Adipositas oder chronisch entzündliche Darmerkrankungen führen zu einer Störung der Darmwandbarriere mit erhöhter Durchlässigkeit für bakterielle Toxine und konsekutiver Entzündungsreaktion. Aus diesem Grund ist die Beurteilung der Darmwanddurchlässigkeit essentieller Bestandteil verschiedener Grundlagenforschungsprojekte. Bisherige Methoden erlauben jedoch keine vollständige und zufriedenstellende Analyse der Darmwandbarriere. \r\nZiel: Ziel dieser Untersuchung ist es die Technik des small angle x-ray-scattering (SAXS) an einem Sepsismodell zu erproben, damit neue Erkenntnisse über die Darmwand zu erlangen und eine neue Technik zu etablieren.\u2028Tiere: 16 wild type Mäuse werden in 2 Gruppen geteilt. Die Kontrollgruppe erhält nur FITC Dextran per Sonde und wird 16h später euthanasiert. Bei den Tieren der zweiten Gruppe wird mittels CLP (cecal ligation and puncture) eine Sepsis erzeugt. Auch diese Tiere erhalten FITC dextran per Sonde. \r\nMethodik: Bei der Euthanasie wird Blut gewonnen und daraus der Serumgehalt von FITC als funktioneller Parameter der Darmdurchlässigkeit spektrophotometrisch bestimmt. Zusätzlich wird die Entzündung der Darmwand in HE Schnitten quantifiziert und der Darm elektronenmikroskopisch untersucht. Zusätzlich werden Ileumabschnitte mittels SAXS untersucht. Die Permeabilitätsparameter zwischen den Gruppen werden verglichen. Zusätzlich werden die Ergebnisse der Standardmethoden mit denen des SAXS korreliert. \r\nDissemination: Bisher gibt es keine Daten zur Darmwandanalyse mittels SAXS in der medizinischen Literatur. Die Ergebnisse sollen hochwertig veröffentlicht und auf internationalen Kongressen präsentiert werden. Zudem legen sie die Basis für weitere Forschungsanträge. Da unzählige Pathologien mit gestörter Darmwandbarriere vergesellschaftet sind und diese Technik auch bei der Versuchstierreduktion hilft, könnte mit dieser Methode durch die Kooperation zwischen Medizinischer Universität Graz und Universität für Bodenkultur Wien wissenschaftliches Neuland ergründet und neue Standards gelegt werden. \r\n\r\n", "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-01-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2018-03-31T02:00:00+02:00", "assignment": "2016-12-12T11:48:08+01:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 54087, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-20", "ethics_committee": null, "edudract_number": null, "persons": [ "4729-50778-12", "4729-54087-10", "4729-82670-12" ] }, { "id": 3794, "title": { "de": "Entwicklungsgrundlagen der Mediaverkalkung", "en": "Developmental Basis of Media Calcification" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-01-01T01:00:00+01:00", "begin_effective": "2015-01-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2018-10-31T01:00:00+01:00", "assignment": "2014-10-24T12:16:43+02:00", "program": 72, "subprogram": null, "organization": 14079, "category": 10, "type": 10, "partner_function": 4, "manager": 74175, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 27537", "ethics_committee": null, "edudract_number": null, "persons": [ "3794-74174-12", "3794-74175-10", "3794-75657-12", "3794-86124-12", "3794-86588-12" ] }, { "id": 3144, "title": { "de": "Nanomedizin für molekulares Imaging und Behandlung von Atherosklerose: Entwicklung und Analyse klinischer Machbarkeit", "en": "Nanomedicine for target-specific imaging and treatment of atherothrombosis : development and initial clinical feasibility" }, "short": "NanoAthero", "url": null, "abstract": { "de": null, "en": "NanoAthero is a European-funded project under the 7th Framework Programme for Research. The main objective of this project is to address more in depth prospects of improved diagnosis and treatment of atherosclerosis by means of nanotechnology. \r\n\r\nFacts & Figures\r\n- Total project volume: EUR 12.8 million \r\n- Project time: five years (1026 person-months)\r\n- Start of the project: 1 February 2013\r\n- 16 partners from 10 countries\r\n\r\nObjectives: \r\n\r\nNanoAthero aims to demonstrate initial clinical feasibility of nanosystems for targeted imaging and treatment of advanced atherosclerotic disease in humans. The nanosystems are assemblies of following components: nanocarrier, targeting, imaging agent/drug. They have proven safety records, and strong preliminary in vitro and in vivo proofs of efficacy are available. Partners have patented and provided evidence of efficacy of carriers and ligands. \r\nOver 5 years, NanoAthero will integrate GMP production, the initiation of clinical investigations in high-risk patients, including the preparation of regulatory dossiers, risk and ethical assessments, and the evaluation of the performance of optimized diagnostic and therapeutic compounds. NanoAthero offers a unique opportunity for combining in-depth knowledge of nanocarrier bioengineering and production with state-of the art expertise in imaging and treatment of cardiovascular patients providing a full bench-to-bedside framework within one collaborative consortium of 16 partners. \r\nNanoAthero gathers together leading chemists, engineers, pharmacists, biologists, toxicologists, clinicians, analysts, ethicists and key-opinion leaders in the field of cardiovascular medicine and early drug development, a European association, 3 SMEs and a large pharmaceutical company (i.e.Bracco). \r\nPhase I clinical trials targeting pivotal pathways in atherothrombosis will be performed with nanosystems for diagnosis and treatment of carotid atheroma and stroke. NanoAthero aims to complete phase I evaluation of two nanosystems: thrombus imaging and plaque stabilization in high-risk patients. Preclinical studies for two nanosystems (one to dissolve blood clots in stroke and one for plaque imaging) will be collaboratively completed and collection of clinical data will be launched. \r\n\r\n" }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2018-01-31T01:00:00+01:00", "assignment": "2013-01-21T11:07:13+01:00", "program": 24, "subprogram": "NMP.2012.1.2-2: Development and phase-I clinical trials of novel therapeutic nanotechnology-enabled systems for the diagnosis and treatment of atherosclerosis.", "organization": 14028, "category": 10, "type": 10, "partner_function": 2, "manager": 52854, "contact": 52854, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "309820", "ethics_committee": null, "edudract_number": null, "persons": [ "3144-50464-12", "3144-52854-10", "3144-56571-12", "3144-88042-12" ] }, { "id": 4759, "title": { "de": "Die Rolle langer, nicht-kodierender RNS in Tumorstammzellen des Nierenzellkarzinoms.", "en": "Role of long non-coding RNAs in renal cancer stem cells." }, "short": "longncRNA in RCC-CSC", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-01-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2017-01-11T10:02:18+01:00", "program": 103, "subprogram": null, "organization": 14056, "category": 10, "type": 10, "partner_function": 4, "manager": 59858, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4759-59858-10" ] }, { "id": 4779, "title": { "de": "Panobinostat reduziert Hypoxie-induzierte Cisplatin Resistenz in nicht-kleinzelligen Lungenkarzinom Zellen durch Destabilisierung vom HIF-1alpha", "en": "Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1alpha destabilization" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-02-01T01:00:00+01:00", "begin_effective": "2017-02-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2017-01-23T13:50:46+01:00", "program": null, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 4, "manager": 50610, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-21", "ethics_committee": null, "edudract_number": null, "persons": [ "4779-50610-10" ] }, { "id": 4766, "title": { "de": "Die Rolle von SIRT1 in der Pathogenese der Spondyloarthritiden", "en": "The role of SIRT1 in the pathogenesis of Spondyloarthritides" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-01-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2017-01-11T14:04:18+01:00", "program": null, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 78952, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 87 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4766-78952-10" ] }, { "id": 4331, "title": { "de": "Mikrobiom interstitieller Pneumonien", "en": "Microbiome of interstitial Pneumonias" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-06-01T02:00:00+02:00", "begin_effective": "2016-06-01T02:00:00+02:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2018-10-08T02:00:00+02:00", "assignment": "2016-02-29T14:55:11+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4784, "title": { "de": "Schmerzmittelreduktion in der Neurochirurgie durch perioperative Behandlung mit transkutaner Vagusnervstimulation.", "en": "Transcutaneous vagus stimulation for reduction of analgetics in neurosurgery" }, "short": "SchTraV", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-06-01T02:00:00+02:00", "begin_effective": "2016-06-01T02:00:00+02:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2020-12-31T01:00:00+01:00", "assignment": 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