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GET /v1/research/project/?format=api&offset=800&ordering=-begin_planned
{ "count": 2140, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=820&ordering=-begin_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=780&ordering=-begin_planned", "results": [ { "id": 6146, "title": { "de": "Vernetzte Muskelzellen bei Inkontinenz", "en": "Anchored Muscle Cells for Incontinence" }, "short": "AMELIE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-09-01T02:00:00+02:00", "end_planned": "2024-12-31T01:00:00+01:00", "end_effective": "2025-08-31T02:00:00+02:00", "assignment": "2020-06-02T11:14:32+02:00", "program": 109, "subprogram": null, "organization": 14063, "category": 10, "type": 10, "partner_function": 2, "manager": 51696, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "874807", "ethics_committee": null, "edudract_number": null, "persons": [ "6146-51696-10" ] }, { "id": 7369, "title": { "de": "Mechanistische Evaluierung eines TRPV6 Ca2+ Kanal Inhibitors", "en": "Mechanistic Evaluation of a TRPV6 Ca2+ channel inhibitor" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2023-12-31T01:00:00+01:00", "end_effective": "2024-10-31T01:00:00+01:00", "assignment": "2023-02-02T14:52:03+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 78591, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 33283", "ethics_committee": null, "edudract_number": null, "persons": [ "7369-78591-10" ] }, { "id": 5988, "title": { "de": "Integrated and standardized NGS workflows for Personalized therapy", "en": "Integrated and standardized NGS workflows for Personalized therapy" }, "short": "Instand-NGS4P", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2025-06-30T02:00:00+02:00", "end_effective": "2025-05-31T02:00:00+02:00", "assignment": "2019-12-09T14:22:21+01:00", "program": 109, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 3, "manager": 51663, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5988-51663-10" ] }, { "id": 6236, "title": { "de": "Effekte der Skalpakupunktur auf die Herzratenvariabilität bei Patienten mit Schlafstörungen", "en": "Effects of Scalp Acupuncture on Heart Rate Variability in Patients with Insomnia" }, "short": "Skalp Akupunktur - HRV - EPU2020", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2020-08-10T10:39:54+02:00", "program": null, "subprogram": null, "organization": 14044, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 762 ], "funder_projectcode": "EPU 35/2019", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 6029, "title": { "de": "Diagnostik und Management fieberhafter Erkrankungen unter Verwendung von personalisierter RNA Molekularsignatur ", "en": "Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis" }, "short": "Diamonds", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2024-12-31T01:00:00+01:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2020-01-17T15:19:36+01:00", "program": 109, "subprogram": null, "organization": 14091, "category": 10, "type": 10, "partner_function": 1, "manager": 51647, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": " 848196", "ethics_committee": null, "edudract_number": null, "persons": [ "6029-62056-12", "6029-51647-10" ] }, { "id": 6081, "title": { "de": "Ein quantitatives Konzept zur Untersuchung von human-assoziierten Antibiotikaresistenzen in Flüsse", "en": "A quantitative concept to study the distribution of human-derived antibiotic resistance in rivers" }, "short": "RIVAR", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2024-08-31T02:00:00+02:00", "assignment": "2020-03-04T10:12:35+01:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 58733, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6081-58733-10", "6081-103077-12" ] }, { "id": 6016, "title": { "de": "Charakterisierung von Veränderungen der Organ Mikroperfusion mit Hilfe von Photoakustischer Bildgebung ", "en": "Microperfusion and fotoacoustic imaging" }, "short": "OMIPAPP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-02-01T01:00:00+01:00", "end_planned": "2023-12-31T01:00:00+01:00", "end_effective": "2023-11-30T01:00:00+01:00", "assignment": "2020-01-09T10:56:42+01:00", "program": 60, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 1, "manager": 50874, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "877103", "ethics_committee": null, "edudract_number": null, "persons": [ "6016-111188-12", "6016-122050-12", "6016-124110-12", "6016-50874-10", "6016-62756-11", "6016-89855-12", "6016-90375-12", "6016-93640-12", "6016-103857-12" ] }, { "id": 6038, "title": { "de": "Biomarker Veränderungen zeigen PAH Progression und Therapieantwort", "en": "Changes in blood derived biomarkers reflect PAH progression and response to targeted therapy" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2020-06-30T02:00:00+02:00", "end_effective": "2020-06-30T02:00:00+02:00", "assignment": "2020-02-03T14:57:40+01:00", "program": null, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 4, "manager": 87980, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2396 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6038-87980-10" ] }, { "id": 6048, "title": { "de": "Efficient Ex Vivo Evaluation of Combined Immunotherapies for Diffuse Large B Cell Lymphoma", "en": "Efficient Ex Vivo Evaluation of Combined Immunotherapies for Diffuse Large B Cell Lymphoma" }, "short": "Immunotherapies for Lymphoma", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2020-02-10T13:46:22+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 94195, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-47", "ethics_committee": null, "edudract_number": null, "persons": [ "6048-94195-10" ] }, { "id": 6211, "title": { "de": "Innovative Pichia pastoris Wirts- und Vektorsysteme", "en": "Innovative Pichia pastoris host and vector systems" }, "short": "PichiaCDLab", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-09-01T02:00:00+02:00", "end_planned": "2023-12-31T01:00:00+01:00", "end_effective": "2024-02-28T01:00:00+01:00", "assignment": "2020-07-23T17:32:58+02:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 2, "manager": 94195, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 23 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6211-94195-10" ] }, { "id": 6323, "title": { "de": "Semantic Image Segmentation by Deep Active Learning in medical imaging applications", "en": "Semantic Image Segmentation by Deep Active Learning in medical imaging applications" }, "short": "SISDAL", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2021-09-30T02:00:00+02:00", "end_effective": "2022-03-31T02:00:00+02:00", "assignment": "2020-10-30T09:25:32+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 50966, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "871262", "ethics_committee": null, "edudract_number": null, "persons": [ "6323-50966-10" ] }, { "id": 6078, "title": { "de": "PICS4HEALTH – „SELFIES“ ZUR DIAGNOSE DER SARKOPENIE", "en": "PICS4HEALTH – „SELFIES“ TO DIAGNOSE SARCOPENIA" }, "short": "PICS4HEALTH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2020-12-31T01:00:00+01:00", "assignment": "2020-03-02T12:36:59+01:00", "program": null, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 50989, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-49", "ethics_committee": null, "edudract_number": null, "persons": [ "6078-50989-10" ] }, { "id": 5984, "title": { "de": "Human Exposome Assessment Platform", "en": " Human Exposome Assessment Platform" }, "short": "HEAP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2024-12-31T01:00:00+01:00", "end_effective": "2025-06-30T02:00:00+02:00", "assignment": "2019-12-09T10:03:39+01:00", "program": 109, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51449, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "874662", "ethics_committee": null, "edudract_number": null, "persons": [ "5984-121589-12", "5984-129215-12", "5984-51449-10", "5984-105945-12" ] }, { "id": 5941, "title": { "de": "Multiskalen-Modellierung von Herzklappenerkrankungen", "en": "Multiscale Modeling of Valvular Heart Diseases - Understanding the Mechanisms of Adverse Remodeling to Improve Precision Medicine." }, "short": "SICVALVES", "url": null, "abstract": { "de": "SICVALVES – Multiskalen-Modellierung von Herzklappenerkrankungen\r\n\r\nMotivation: Herzklappenerkrankungen sind eine zunehmende gesundheitliche Belastung für die alternde Bevölkerung, bei der allein die Aortenklappenstenose bei mehr als 12% der Patienten >70 Jahre vorherrscht. Es ist eine chronisch-progressive Erkrankung, die mit Geschlecht und Alter variiert. Bestehende Leitlinien für die Behandlungsplanung verwenden jedoch nur grobe Funktionsparameter, die die interindividuelle Variabilität nicht berücksichtigen und weit von den Anforderungen der Präzisionsmedizin entfernt sind. Im Zeitalter der digitalen Medizin haben Computermodelle das Potenzial, wichtige pathophysiologische Mechanismen zu entschlüsseln und zur personalisierten Präzisionsmedizin beizutragen.\r\nZiele: Die Nutzung fortgeschrittener Modelle auf Zell-, Gewebe- und Organebene, um mechanistische Erkenntnisse über Auslöser von ventrikulären Arrhythmien, diastolischer und systolischer Dysfunktion und myokardialen metabolischen Veränderungen zu gewinnen und zu untersuchen wie sich diese Prozesse gegenseitig verstärken. Geschlechtsspezifische Unterschiede müssen systematisch berücksichtigt werden. Letztlich sollen die Modelle zur Verbesserung der Diagnostik, Risikobewertung und Behandlungsplanung von Herzklappenerkrankungen beitragen.\r\nMethoden: Basierend auf unseren bisherigen Arbeiten werden wir bestehende computergestützte Modelle der Biomechanik, Elektrophysiologie und der Hämodynamik technologisch weiterentwickeln, testen und validieren. Zur Modellparametrisierung verwenden wir bestehende multidimensionale klinische Daten (Bildgebung, Sensortechnik, Systembiologie) aus eigenen früheren Untersuchungen bei Patienten mit Herzklappenerkrankungen. Die Validierung der Genauigkeit der Modelle zur Vorhersage von mechanistischen Veränderungen erfolgt anhand von Daten, die vor und nach dem Einsatz von künstlichen Klappenprothesen gewonnen werden.\r\nInnovation: Fortgeschrittene computergestützte Werkzeuge werden dafür genutzt, um personalisierte Modelle zu erstellen und diese zur quantitativen Bewertung von hypertropischem Remodeling und der Neigung zu Arrhythmien zu verwenden. Es werden vollständig neue Methoden entwickelt um zugrunde liegenden Mechanismen, Verlauf und Symptome die bei Herzklappenerkrankungen auftreten zu verstehen. Des Weiteren wird ein virtueller Simulator für die patientenspezifische Planung der Therapie von Herzklappenerkrankungen entwickelt, der die Wirksamkeit der künstlichen Klappenprothesen verbessert und die Sterblichkeit bei Patienten reduziert.", "en": "SICVALVES – Multiscale modeling of Valvular Heart Diseases\r\nUnderstanding the mechanisms of adverse remodeling to improve precision medicine\r\n\r\nBackground: Valvular Heart Diseases (VHD) are a detrimental health burden to the aging population where aortic valve stenosis alone has reached an incidence of more than 12% of patients >70y. It is a chronic-progressive disease that varies with gender and age. If left untreated, VHDs can cause malignant arrhythmias and severe heart failure. However, existing guidelines for treatment planning are using only rough function parameters that fail to account for inter-individual variability and are far away from the demands of precision medicine. In the age of digital medicine, computational modeling has the potential to unveil important pathophysiological mechanisms and to contribution towards personalized precision medicine.\r\nObjectives: To use advanced models of the cell, tissue, and organ level in VHD to gain mechanistic insights about triggers of ventricular arrhythmias, diastolic, and systolic dysfunction and myocardial metabolic alterations and how these processes reinforce each other. Gender differences will be systematically taken into account. Ultimately, models shall contribute to improve diagnostics, risk assessment, and treatment planning of VHDs.\r\nMethods: Based on our previous work, we will technologically advance, test, and validate existing computational models of biomechanics, electrophysiology, and hemodynamics. For model parameterization we use existing multidimensional clinical data (imaging, sensors, omics) from own previous research in patients with VHD (obtained before and after valve replacement). Validation of the model's accuracy to predict mechanistic changes will be done with data obtained before and after aortic valve replacement.\r\nInnovation: Advanced computational models will be leveraged to build personalized models and use these for quantitative assessment of hypertrophic remodeling and propensity for arrhythmias. Novel methodologies will be developed to understand important mechanisms of adverse remodeling in VHDs, as well as to improve patient care by optimizing patient selection and precision treatment planning in valve disease." }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2024-08-31T02:00:00+02:00", "assignment": "2019-10-28T13:38:14+01:00", "program": 112, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 79791, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I4652", "ethics_committee": null, "edudract_number": null, "persons": [ "5941-119147-12", "5941-122514-12", "5941-79791-10", "5941-91352-12" ] }, { "id": 6015, "title": { "de": "CETOCOEN Excellence", "en": "CETOCOEN Excellence" }, "short": "CETOCOEN Excellence", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2020-01-07T14:17:10+01:00", "program": 109, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51449, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6015-51449-10", "6015-99976-12" ] }, { "id": 5872, "title": { "de": "Veränderungen der Tränenfunktion und der Augenoberfläche bei PatientInnen mit Vitiligo", "en": "Tear function and ocular surface disorders in patients with vitiligo" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-12-01T01:00:00+01:00", "begin_effective": "2019-12-01T01:00:00+01:00", "end_planned": "2022-12-01T01:00:00+01:00", "end_effective": "2024-03-31T01:00:00+01:00", "assignment": "2019-07-30T16:29:58+02:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5927, "title": { "de": "Maßnahmen zur \r\nAttraktivierung der Allgemeinmedizin \r\n", "en": "Maßnahmen zur \r\nAttraktivierung der Allgemeinmedizin \r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-11-01T01:00:00+01:00", "begin_effective": "2019-11-01T01:00:00+01:00", "end_planned": "2020-10-31T01:00:00+01:00", "end_effective": "2020-10-31T01:00:00+01:00", "assignment": "2019-10-16T10:46:08+02:00", "program": null, "subprogram": null, "organization": 27964, "category": 10, "type": 10, "partner_function": 4, "manager": 51098, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2160 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5927-51098-10" ] }, { "id": 5989, "title": { "de": "Role of antimicrobial peptides in immune suppression", "en": "Role of antimicrobial peptides in immune suppression" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-11-01T01:00:00+01:00", "begin_effective": "2019-11-01T01:00:00+01:00", "end_planned": "2020-05-30T02:00:00+02:00", "end_effective": "2020-08-31T02:00:00+02:00", "assignment": "2019-12-09T15:52:21+01:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 87275, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5989-87275-10" ] }, { "id": 6021, "title": { "de": "Der Effekt von Palmitylethanolamid auf die zentrale und periphere Sensibilisierung bei gesunden Probanden - Pilotstudie", "en": "The Effect of Palmitylethanolamide on central and peripheral sensitization in healthy volunteers - Pilot Study" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-11-01T01:00:00+01:00", "begin_effective": "2019-11-01T01:00:00+01:00", "end_planned": "2020-07-06T02:00:00+02:00", "end_effective": "2021-12-31T01:00:00+01:00", "assignment": "2020-01-15T14:51:01+01:00", "program": null, "subprogram": null, "organization": 14070, "category": 10, "type": 10, "partner_function": 4, "manager": 58422, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6021-58422-10" ] }, { "id": 6001, "title": { "de": "Das Darm-Mikrobiom im Verlauf hämato-/onkologischer Erkrankungen", "en": "The Gut Microbiome in Haemato-/Oncological Patients" }, "short": "MikroPHiOm", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-11-01T01:00:00+01:00", "begin_effective": "2019-11-01T01:00:00+01:00", "end_planned": "2024-10-31T01:00:00+01:00", "end_effective": "2024-10-31T01:00:00+01:00", "assignment": "2019-12-16T10:01:50+01:00", "program": null, "subprogram": null, "organization": 14095, "category": 10, "type": 10, "partner_function": 4, "manager": 56810, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6001-56810-10" ] } ] }