Project List
List projects.
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GET /v1/research/project/?format=api&offset=80
{ "count": 2260, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=100", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=60", "results": [ { "id": 4125, "title": { "de": "Die Energieversorgung des Endoplasmatischen Retikulums", "en": "The Energy Supply of the Endoplasmic Reticulum" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-10-01T02:00:00+02:00", "begin_effective": "2016-01-01T01:00:00+01:00", "end_planned": "2018-09-30T02:00:00+02:00", "end_effective": "2019-09-30T02:00:00+02:00", "assignment": "2015-10-15T12:04:23+02:00", "program": 72, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 50810, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 28529", "ethics_committee": null, "edudract_number": null, "persons": [ "4125-50810-10" ] }, { "id": 3116, "title": { "de": "Qualifizierungsnetz Humantechnologie Projekt Nr. 836248", "en": "Qualifizierungsnetz Humantechnologie" }, "short": "QnHT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2014-09-30T02:00:00+02:00", "assignment": "2012-12-19T11:08:50+01:00", "program": null, "subprogram": null, "organization": 14026, "category": 10, "type": 10, "partner_function": 4, "manager": 51344, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3116-51344-10" ] }, { "id": 3944, "title": { "de": "Die antithrombotische Wirkung von S-NO-Albumin in Neugeborenen und Erwachsenen", "en": "The antithrombotic action of S-NO-Albumin in neonates and adults" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-06-01T02:00:00+02:00", "begin_effective": "2015-06-01T02:00:00+02:00", "end_planned": "2015-12-01T01:00:00+01:00", "end_effective": "2015-12-01T01:00:00+01:00", "assignment": "2015-03-12T12:31:29+01:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 4, "manager": 50068, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3944-50068-10" ] }, { "id": 3830, "title": { "de": "Kurzfristige Auswirkung des statischen Dehnens auf neuromechnische Eigenschaften", "en": "Temporal effects of acute static stretching on neuromechanics of the muscle-tendon-unit" }, "short": "STRETCH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-07-01T02:00:00+02:00", "begin_effective": "2014-07-01T02:00:00+02:00", "end_planned": "2017-06-30T02:00:00+02:00", "end_effective": "2018-09-30T02:00:00+02:00", "assignment": "2014-12-04T11:28:45+01:00", "program": 72, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 2, "manager": 51814, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P27665 ", "ethics_committee": null, "edudract_number": null, "persons": [ "3830-51814-10" ] }, { "id": 3312, "title": { "de": "Anti-atherosclerotic Effects of Ligustrazine", "en": "Anti-atherosclerotic Effects of Ligustrazine" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-28T02:00:00+02:00", "begin_effective": "2013-07-28T02:00:00+02:00", "end_planned": "2014-06-28T02:00:00+02:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2013-06-27T11:34:02+02:00", "program": 92, "subprogram": "Eurasia Pacific Uninet", "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3312-57932-10" ] }, { "id": 3647, "title": { "de": "Vascular endothelial dysfunction: The putative interface of emerging cardiovascular risk factors affecting populations living with and without HIV in Sub-Saharan Africa", "en": "Vascular endothelial dysfunction: The putative interface of emerging cardiovascular risk factors affecting populations living with and without HIV in Sub-Saharan Africa" }, "short": "ENDOAFRICA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-06-01T02:00:00+02:00", "begin_effective": "2014-04-01T02:00:00+02:00", "end_planned": "2016-05-31T02:00:00+02:00", "end_effective": "2018-12-31T01:00:00+01:00", "assignment": "2014-04-30T16:02:52+02:00", "program": null, "subprogram": "ERAFRICA", "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3647-50514-12", "3647-57932-10", "3647-51812-12" ] }, { "id": 3389, "title": { "de": "ENDOTHELIAL FUNCTION, RENO-VASCULAR AND NEUROHORMONAL RESPONSES DURING ORTHOSTATIC SYNCOPE AND RECOVERY: A GENDER COMPARISON STUDY (EROS)", "en": "Endothelial function, reno-vascular and neurohormonal responses during orthostatic syncope and recovery: A gender comparative study" }, "short": "EROS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2013-09-30T12:37:49+02:00", "program": null, "subprogram": "Italian Space Agency (ASI); human exploration program", "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1527 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3389-57932-10" ] }, { "id": 4749, "title": { "de": "STAND UP AND GO", "en": "STAND UP AND GO" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-01-01T01:00:00+01:00", "end_planned": "2018-12-31T01:00:00+01:00", "end_effective": "2019-05-31T02:00:00+02:00", "assignment": "2016-12-22T11:17:24+01:00", "program": null, "subprogram": "HTI Land Steiermark", "organization": 14010, "category": 10, "type": 10, "partner_function": 3, "manager": 57932, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 55 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4749-57932-10" ] }, { "id": 4852, "title": { "de": "Effect of salt intake on vascular response during standing up", "en": "Effects of salt intake on vascular response during standing up" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-09-01T02:00:00+02:00", "begin_effective": "2016-09-01T02:00:00+02:00", "end_planned": "2017-08-31T02:00:00+02:00", "end_effective": "2017-08-31T02:00:00+02:00", "assignment": "2017-02-22T12:10:18+01:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4852-57932-10" ] }, { "id": 6195, "title": { "de": "TOPICAL TEAM: PATHOPHYSIOLOGY, RISK, AND CLINICAL PRESENTATION OF VENOUS THROMBOEMBOLISM(VTE) AND EVALUATION OF ITS PREVENTION, DIAGNOSIS, MITIGATION AND MANAGEMENT STRATEGIES IN SPACEFLIGHT", "en": "TOPICAL TEAM: PATHOPHYSIOLOGY, RISK, AND CLINICAL PRESENTATION OF VENOUS THROMBOEMBOLISM(VTE) AND EVALUATION OF ITS PREVENTION, DIAGNOSIS, MITIGATION AND MANAGEMENT STRATEGIES IN SPACEFLIGHT" }, "short": null, "url": null, "abstract": { "de": "We aim to asess risk of thrombosis in space", "en": null }, "begin_planned": "2020-08-01T02:00:00+02:00", "begin_effective": "2020-08-01T02:00:00+02:00", "end_planned": "2022-05-31T02:00:00+02:00", "end_effective": "2023-05-31T02:00:00+02:00", "assignment": "2020-07-09T14:13:07+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1203 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6195-57932-10", "6195-97690-12" ] }, { "id": 5864, "title": { "de": "Elucidating the impact(s) of spaceflight on circulatory vascular function: clinical, genomics, transcriptomics, and proteomics parameters", "en": "Elucidating the impact(s) of spaceflight on circulatory vascular function: clinical, genomics, transcriptomics, and proteomics parameters" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-04-01T02:00:00+02:00", "begin_effective": "2019-07-01T02:00:00+02:00", "end_planned": "2022-03-31T02:00:00+02:00", "end_effective": "2023-12-31T01:00:00+01:00", "assignment": "2019-07-16T10:02:59+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5864-57932-10" ] }, { "id": 4385, "title": { "de": "Exzellenzzentrum für superauflösende Mikroskopie und zelluläre\r\nUltrastrukturforschung", "en": "Exzellenzzentrum für superauflösende Mikroskopie und zelluläre\r\nUltrastrukturforschung" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-11-01T01:00:00+01:00", "begin_effective": "2013-11-01T01:00:00+01:00", "end_planned": "2020-03-30T02:00:00+02:00", "end_effective": "2020-03-30T02:00:00+02:00", "assignment": "2016-04-07T16:32:08+02:00", "program": null, "subprogram": "HRSM 2013", "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 51860, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4385-51860-10" ] }, { "id": 8589, "title": { "de": "Rejuvenated yeasts for better biorefineries", "en": "Rejuvenated yeasts for better biorefineries" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-31T01:00:00+01:00", "begin_effective": "2025-01-31T01:00:00+01:00", "end_planned": "2028-01-30T01:00:00+01:00", "end_effective": "2028-01-30T01:00:00+01:00", "assignment": "2025-01-10T10:29:19+01:00", "program": 94, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 1, "manager": 113130, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8589-113130-10", "8589-132237-12" ] }, { "id": 6883, "title": { "de": "Früherkennung von Therapieresistenzen bei Prostatakrebs - In situ Detektion von Androgen-Rezeptor Splice Varianten", "en": "Early detection of therapy resistance in prostate cancer - In situ detection of Androgen receptor splice variants" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2022-01-01T01:00:00+01:00", "end_planned": "2017-07-31T02:00:00+02:00", "end_effective": "2023-12-31T01:00:00+01:00", "assignment": "2022-01-19T10:08:55+01:00", "program": null, "subprogram": "MEFO - Diagnostikum Preidler/Szolar-Stipendium", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 66435, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-70", "ethics_committee": null, "edudract_number": null, "persons": [ "6883-66435-10" ] }, { "id": 6542, "title": { "de": "CBmed: 2.22A - Next generation drug screening platform for precision oncology services", "en": "CBmed: 2.22A - Next generation drug screening platform for precision oncology services" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-01-01T01:00:00+01:00", "begin_effective": "2019-01-01T01:00:00+01:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2023-12-31T01:00:00+01:00", "assignment": "2021-04-28T14:22:28+02:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 66435, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6542-66435-10" ] }, { "id": 4053, "title": { "de": "Einfluss proinflammatorischer Zytokine auf plazentales Fraktalkin und die Interaktion mit Monozyten", "en": "The role of pro-inflammatory cytokines on placental fractalkine and its interaction with monocytes" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-07-01T02:00:00+02:00", "begin_effective": "2015-07-01T02:00:00+02:00", "end_planned": "2017-06-30T02:00:00+02:00", "end_effective": "2018-03-31T02:00:00+02:00", "assignment": "2015-07-08T16:58:48+02:00", "program": 79, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 53232, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4053-53232-10" ] }, { "id": 4967, "title": { "de": "Der Einfluss von Angiotensin II auf das plazentale Fraktalkin", "en": "The role of angiotensin II on placental fractalkine" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2021-09-30T02:00:00+02:00", "assignment": "2017-05-24T14:53:01+02:00", "program": 71, "subprogram": "DACH", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 53232, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I 3304", "ethics_committee": null, "edudract_number": null, "persons": [ "4967-53232-10" ] }, { "id": 5347, "title": { "de": "Effizienter Mitochondrien-Transfer", "en": "Effizienter Mitochondrien-Transfer" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-04-01T02:00:00+02:00", "begin_effective": "2018-04-01T02:00:00+02:00", "end_planned": "2019-03-31T01:00:00+01:00", "end_effective": "2022-12-31T01:00:00+01:00", "assignment": "2018-04-18T12:34:44+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-02", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4653, "title": { "de": "Flexibilität in der Organforschung", "en": "Flexibility in Organ Research" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-10-01T02:00:00+02:00", "begin_effective": "2017-02-01T01:00:00+01:00", "end_planned": "2019-09-30T02:00:00+02:00", "end_effective": "2021-01-31T01:00:00+01:00", "assignment": "2016-10-14T13:09:27+02:00", "program": 64, "subprogram": "Partnership in Research", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 76930, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9, 23 ], "funder_projectcode": "PIR00007", "ethics_committee": null, "edudract_number": null, "persons": [ "4653-50394-12", "4653-76930-10", "4653-51718-12", "4653-128875-12" ] }, { "id": 4847, "title": { "de": "Hochauflösende In-silico Modelle der Gesamten Herzfunktion", "en": "High-resolution In Silico Models of Total Heart Function" }, "short": "InsiliCardio", "url": null, "abstract": { "de": "Fortschritte bei der Entwicklung von tomographischen Verfahren ermöglichen in beispielloser Weise die Anatomie des Herzens abzubilden. Allerdings hatten diese Technologien bisher einen relativ geringen Einfluss auf die Entwicklung von medizinischen Implantaten oder die Verbesserung von klinischen Behandlungsmethoden. \r\nDer Einsatz von bildgebenden Verfahren zur Extraktion von wichtigen funktionellen Informationen und der Kopplung von Bildinformationen mit physiologischen Aspekten, die nicht durch Bildgebung allein verstanden werden können, stellt eine große Herausforderung dar. In silico Modelle, also computerunterstützte Simulationen, bergen enormes Potenzial zur Bewältigung dieser Herausforderungen und können zu einem besseren Verständnis der Herzfunktion, sei es im gesunden oder auch im erkrankten Zustand, führen. Ein entscheidender Vorteil ist hierbei die Möglichkeit diagnostische und therapeutische Methoden zu optimieren ohne dabei Patienten zusätzlichen Risiken oder Schmerzen auszusetzen. In silico Experimente können somit bei der Untersuchung von klinisch relevanten Problemen, wie zum Beispiel Herzklappenchirurgie, Ballon-Angioplastie oder Stenting, äußerst hilfreich sein. \r\nDie Herzfunktion ergibt sich aus der Interaktion verschiedener Physiken, unter anderem der Elektrophysiologie, der Strukturmechanik und der Strömungsmechanik. Während die beteiligten Physiken klar bidirektional wechselwirken, werden sie in praktisch allen Studien isoliert betrachtet. Dies ist zu einem guten Teil auf die Komplexität von Multiphysik-Modellen und den Schwierigkeiten, die bei der Entwicklung von modernen numerischen Methoden und deren effizienten Implementierung auf modernen Rechnerarchitekturen auftauchen, zurückzuführen. Die Bewältigung dieser Herausforderungen ist das zentrale Themas dieses Projektes und die Durchführung setzt auf die Kombination der Expertisen der Antragsteller: Christoph Augustin und Gernot Plank in der Modellierung der Elektrophysiologie und der Strukturmechanik und Shawn Shadden in der Computermodellierung des Blutflusses. \r\nDieses ambitionierte Unterfangen geht weit über den aktuellen Stand der Technik hinaus. Kombinierte Modelle von Herz und Blutgefäßen ermöglichen die Berechnung von natürlichen Randbedingungen für die Simulation des Blutflusses und das Studium von Rückkopplungsmechanismen die die Pumpleistung des Herzens beeinflussen können. Im Endeffekt wird dieses Modell eines der modernsten Werkzeuge der Grundlagenforschung sein, das einen mechanistischen Einblick in die Herzpumpfunktion gewährt. Von wesentlicher Bedeutung ist in diesem Kontext auch die Überprüfung, Parametrisierung und Validierung dieses Modells mit klinischen Datensätzen, die von klinischen Partnern zur Verfügung gestellt werden. \r\nDas Ziel dieser Forschung ist ein innovatives Multiphysik-Computermodell der gesamten Herzfunktion um eine biophysikalisch detaillierte und bidirektional gekoppelte Erforschung der elektromechanischen Funktion des Herzens im gesunden wie im kranken Zustand zu ermöglichen.", "en": "Advances in medical imaging have enabled unprecedented ability to image cardiac anatomy and function. So far these technologies have had relatively modest clinical impact as the analysis of such rich multi-modal datasets has proven challenging. In silico models hold vast potential to better harness such datasets by enabling their integration into quantitative frameworks that can aid in gaining better mechanistic insight into cardiac function in health and disease, and thus paving the way towards optimal therapeutic strategies.\r\nOur objective is to develop the most advanced biophysically detailed in-silico model of total electro-mechano-fluidic function of the heart. This model will be parametrized, verified and used to study cause-effect relationships between flow and pressure and their impact upon pumping performance. A novel set of features such as combined models of both heart and attached outflow vessels and the computational efficiency will provide a unique platform for translational research.\r\nThis ambitious endeavor is feasible only by combining the expertise of the applicant in modeling soft tissue mechanics and his supervisors in modeling electrophysiology (Gernot Plank, MUG) and blood flow (Shawn Shadden, UC Berkeley). Clinical input and datasets for model parametrization and validation are provided by Titus Kühne (DHZ Berlin) and by clinical collaborators of Prof. Shadden at UCSF. During the return-phase, the applicant will use the infrastructure of Prof. Plank’s lab and the large network of academic and industrial collaborations as an incubator for building up his own research group in computational hemodynamics. This is ideal in many regards, as the expertise of the applicant's group will be entirely orthogonal to the expertise in Prof. Plank's lab, thus promoting a fast pathway towards full indepence, and core expertise necessary for further developing and maintaining a highly complex computing environment is synergistically shared between the labs." }, "begin_planned": "2017-06-01T02:00:00+02:00", "begin_effective": "2017-03-01T01:00:00+01:00", "end_planned": "2020-05-31T02:00:00+02:00", "end_effective": "2019-08-31T02:00:00+02:00", "assignment": "2017-02-20T09:41:41+01:00", "program": 109, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 79791, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "750835", "ethics_committee": null, "edudract_number": null, "persons": [ "4847-79791-10" ] } ] }