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GET /v1/research/project/?format=api&offset=760&ordering=-begin_effective
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=780&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=740&ordering=-begin_effective", "results": [ { "id": 6476, "title": { "de": "Cell culture system for antiviral testing", "en": "Cell culture system for antiviral testing" }, "short": "WP 91011", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2021-03-03T15:30:32+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6476-51663-10" ] }, { "id": 6169, "title": { "de": "Etablierung von in virto Modellen für die Krebsfroschung", "en": "Establishing in vitro model for cancer research" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-05-31T02:00:00+02:00", "end_effective": "2021-10-31T02:00:00+02:00", "assignment": "2020-06-24T10:49:00+02:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 59183, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6169-100134-12", "6169-59183-10", "6169-65239-12", "6169-79614-12", "6169-51930-12" ] }, { "id": 6408, "title": { "de": "Psychosoziale Auswirkungen der SARS-CoV-2 Pandemie auf MitarbeiterInnen der Landeskrankenhäuser in der Steiermark", "en": "Psychosocial consequences of SARS-CoV-2 on individuals working in hospitals in styria" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2021-01-13T11:49:13+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 50654, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6408-50654-10" ] }, { "id": 6124, "title": { "de": "Geruchs- und Geschmackswahrnehmung bei bipolarer Störung ", "en": "Olfactory and gustatory perception in bipolar disorder" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-12-31T01:00:00+01:00", "assignment": "2020-04-28T17:09:43+02:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 2, "manager": 50654, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6124-50654-10", "6124-79454-12", "6124-79771-12", "6124-79733-12", "6124-86429-12", "6124-91818-12", "6124-92607-12", "6124-95403-12" ] }, { "id": 5941, "title": { "de": "Multiskalen-Modellierung von Herzklappenerkrankungen", "en": "Multiscale Modeling of Valvular Heart Diseases - Understanding the Mechanisms of Adverse Remodeling to Improve Precision Medicine." }, "short": "SICVALVES", "url": null, "abstract": { "de": "SICVALVES – Multiskalen-Modellierung von Herzklappenerkrankungen\r\n\r\nMotivation: Herzklappenerkrankungen sind eine zunehmende gesundheitliche Belastung für die alternde Bevölkerung, bei der allein die Aortenklappenstenose bei mehr als 12% der Patienten >70 Jahre vorherrscht. Es ist eine chronisch-progressive Erkrankung, die mit Geschlecht und Alter variiert. Bestehende Leitlinien für die Behandlungsplanung verwenden jedoch nur grobe Funktionsparameter, die die interindividuelle Variabilität nicht berücksichtigen und weit von den Anforderungen der Präzisionsmedizin entfernt sind. Im Zeitalter der digitalen Medizin haben Computermodelle das Potenzial, wichtige pathophysiologische Mechanismen zu entschlüsseln und zur personalisierten Präzisionsmedizin beizutragen.\r\nZiele: Die Nutzung fortgeschrittener Modelle auf Zell-, Gewebe- und Organebene, um mechanistische Erkenntnisse über Auslöser von ventrikulären Arrhythmien, diastolischer und systolischer Dysfunktion und myokardialen metabolischen Veränderungen zu gewinnen und zu untersuchen wie sich diese Prozesse gegenseitig verstärken. Geschlechtsspezifische Unterschiede müssen systematisch berücksichtigt werden. Letztlich sollen die Modelle zur Verbesserung der Diagnostik, Risikobewertung und Behandlungsplanung von Herzklappenerkrankungen beitragen.\r\nMethoden: Basierend auf unseren bisherigen Arbeiten werden wir bestehende computergestützte Modelle der Biomechanik, Elektrophysiologie und der Hämodynamik technologisch weiterentwickeln, testen und validieren. Zur Modellparametrisierung verwenden wir bestehende multidimensionale klinische Daten (Bildgebung, Sensortechnik, Systembiologie) aus eigenen früheren Untersuchungen bei Patienten mit Herzklappenerkrankungen. Die Validierung der Genauigkeit der Modelle zur Vorhersage von mechanistischen Veränderungen erfolgt anhand von Daten, die vor und nach dem Einsatz von künstlichen Klappenprothesen gewonnen werden.\r\nInnovation: Fortgeschrittene computergestützte Werkzeuge werden dafür genutzt, um personalisierte Modelle zu erstellen und diese zur quantitativen Bewertung von hypertropischem Remodeling und der Neigung zu Arrhythmien zu verwenden. Es werden vollständig neue Methoden entwickelt um zugrunde liegenden Mechanismen, Verlauf und Symptome die bei Herzklappenerkrankungen auftreten zu verstehen. Des Weiteren wird ein virtueller Simulator für die patientenspezifische Planung der Therapie von Herzklappenerkrankungen entwickelt, der die Wirksamkeit der künstlichen Klappenprothesen verbessert und die Sterblichkeit bei Patienten reduziert.", "en": "SICVALVES – Multiscale modeling of Valvular Heart Diseases\r\nUnderstanding the mechanisms of adverse remodeling to improve precision medicine\r\n\r\nBackground: Valvular Heart Diseases (VHD) are a detrimental health burden to the aging population where aortic valve stenosis alone has reached an incidence of more than 12% of patients >70y. It is a chronic-progressive disease that varies with gender and age. If left untreated, VHDs can cause malignant arrhythmias and severe heart failure. However, existing guidelines for treatment planning are using only rough function parameters that fail to account for inter-individual variability and are far away from the demands of precision medicine. In the age of digital medicine, computational modeling has the potential to unveil important pathophysiological mechanisms and to contribution towards personalized precision medicine.\r\nObjectives: To use advanced models of the cell, tissue, and organ level in VHD to gain mechanistic insights about triggers of ventricular arrhythmias, diastolic, and systolic dysfunction and myocardial metabolic alterations and how these processes reinforce each other. Gender differences will be systematically taken into account. Ultimately, models shall contribute to improve diagnostics, risk assessment, and treatment planning of VHDs.\r\nMethods: Based on our previous work, we will technologically advance, test, and validate existing computational models of biomechanics, electrophysiology, and hemodynamics. For model parameterization we use existing multidimensional clinical data (imaging, sensors, omics) from own previous research in patients with VHD (obtained before and after valve replacement). Validation of the model's accuracy to predict mechanistic changes will be done with data obtained before and after aortic valve replacement.\r\nInnovation: Advanced computational models will be leveraged to build personalized models and use these for quantitative assessment of hypertrophic remodeling and propensity for arrhythmias. Novel methodologies will be developed to understand important mechanisms of adverse remodeling in VHDs, as well as to improve patient care by optimizing patient selection and precision treatment planning in valve disease." }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2024-08-31T02:00:00+02:00", "assignment": "2019-10-28T13:38:14+01:00", "program": 112, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 79791, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I4652", "ethics_committee": null, "edudract_number": null, "persons": [ "5941-79791-10", "5941-91352-12", "5941-119147-12", "5941-122514-12" ] }, { "id": 6100, "title": { "de": "In-vitro Verifikation von Virus-Inhibitoren", "en": "In-vitro verification of virus inhibitors" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-16T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2020-09-30T02:00:00+02:00", "end_effective": "2020-10-31T01:00:00+01:00", "assignment": "2020-03-16T13:55:16+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-50", "ethics_committee": null, "edudract_number": null, "persons": [ "6100-51663-10" ] }, { "id": 6103, "title": { "de": "Untersuchung der immunstimulierenden Wirkung von humanem Albumin in PBMC", "en": "Investigation of the immune stimulating effects of human albumin in PBMC" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-08-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2020-08-31T02:00:00+02:00", "assignment": "2020-03-23T15:23:30+01:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 4, "manager": 90044, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6103-90044-10" ] }, { "id": 6081, "title": { "de": "Ein quantitatives Konzept zur Untersuchung von human-assoziierten Antibiotikaresistenzen in Flüsse", "en": "A quantitative concept to study the distribution of human-derived antibiotic resistance in rivers" }, "short": "RIVAR", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2024-08-31T02:00:00+02:00", "assignment": "2020-03-04T10:12:35+01:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 58733, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6081-58733-10", "6081-103077-12", "6081-113950-12" ] }, { "id": 6079, "title": { "de": "Postoperative Schmerzerhebung bei Kindern nach tageschirurgischen Eingriffen ", "en": "At home pain assessment in postoperative children and adolescents after day surgery " }, "short": "PAIN-DAYS", "url": null, "abstract": { "de": "Das Schmerzmanagement nach tageschirurgischen Eingriffen sollte den gleichen Standards genügen wie nach stationären Eingriffen. Dies wird dadurch erschwert, dass zu Hause die Eltern für das Schmerzmanagement verantwortlich sind. Um die Eltern dabei zu unterstützen, ist ein Messverfahren erforderlich, das die Schmerzen und dessen Begleitaspekte präzise misst. In diesem Projekt werden Situationen identifiziert, die mit hohen Schmerzen bei Kindern nach tageschirurgischen Eingriffen verbunden sind. Dafür wird die wissenschaftliche Literatur aufgearbeitet, postoperative Kinder interviewt und Expertendiskussionen geführt. Darauf aufbauend werden Items entwickelt, die mit Modellen der probabilistischen Testtheorie analysiert werden.", "en": null }, "begin_planned": "2019-08-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2023-07-31T02:00:00+02:00", "end_effective": "2024-03-31T01:00:00+01:00", "assignment": "2020-03-02T14:20:17+01:00", "program": null, "subprogram": null, "organization": 14026, "category": 10, "type": 10, "partner_function": 4, "manager": 67207, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6079-67207-10" ] }, { "id": 6426, "title": { "de": "MicroMOOD", "en": "MicroMOOD" }, "short": "MicroMOOD", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2021-04-01T02:00:00+02:00", "end_effective": "2022-12-31T01:00:00+01:00", "assignment": "2021-01-26T18:49:05+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 3, "manager": 99972, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6426-99972-10" ] }, { "id": 6065, "title": { "de": "Klinische und molekulargenetische Daten von Kindern und Jugendlichen mit spinalem Ependymomen", "en": "Clinical and molecular data of children and adolescents with spinal cord ependymoma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2020-09-01T02:00:00+02:00", "end_effective": "2021-02-28T01:00:00+01:00", "assignment": "2020-02-24T09:40:40+01:00", "program": null, "subprogram": null, "organization": 14092, "category": 10, "type": 10, "partner_function": 2, "manager": 51369, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6065-51369-10" ] }, { "id": 6183, "title": { "de": "Kann der BAT Inhibitionstest die Stichprovokation ersetzen?", "en": "Is the BAT inhibition able to replace sting challenges?" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2024-03-31T01:00:00+01:00", "end_effective": "2025-09-30T02:00:00+02:00", "assignment": "2020-07-02T20:47:26+02:00", "program": 108, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 87717, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI836", "ethics_committee": null, "edudract_number": null, "persons": [ "6183-87717-10" ] }, { "id": 6383, "title": { "de": "Assoziation von ABH(O) und Lewis Blutgruppen Antigenen und COVID- 19: eine retrospektive Studie.", "en": "Blood Groups in Infection and Host Susceptibility for COVID-19: a retrospective study." }, "short": "ABO und COVID-19", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2021-04-01T02:00:00+02:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2020-12-21T11:50:01+01:00", "program": null, "subprogram": null, "organization": 14058, "category": 10, "type": 10, "partner_function": 4, "manager": 51964, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6383-51964-10" ] }, { "id": 6068, "title": { "de": "Konnektivität eines bewegungssensitiven Neurons in Mantis", "en": "Connectivity of a Praying Mantis Movement Detecting Neuron" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2023-04-01T02:00:00+02:00", "end_effective": "2025-09-30T02:00:00+02:00", "assignment": "2020-02-25T13:48:41+01:00", "program": 72, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 82600, "contact": null, "status": 2, "research": 1, "grant": 30, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P32376", "ethics_committee": null, "edudract_number": null, "persons": [ "6068-82600-10" ] }, { "id": 6017, "title": { "de": "Tracking General Movements - An Observing‐the‐Observer Approach to Understand and Enhance Clinical Reasoning for the General Movement Assessment", "en": "Tracking General Movements - An Observing‐the‐Observer Approach to Understand and Enhance Clinical Reasoning for the General Movement Assessment" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2023-12-31T01:00:00+01:00", "end_effective": "2025-09-30T02:00:00+02:00", "assignment": "2020-01-09T12:00:04+01:00", "program": 108, "subprogram": null, "organization": 14068, "category": 10, "type": 10, "partner_function": 4, "manager": 58883, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI811", "ethics_committee": null, "edudract_number": null, "persons": [ "6017-88853-11", "6017-58883-10" ] }, { "id": 7369, "title": { "de": "Mechanistische Evaluierung eines TRPV6 Ca2+ Kanal Inhibitors", "en": "Mechanistic Evaluation of a TRPV6 Ca2+ channel inhibitor" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2023-12-31T01:00:00+01:00", "end_effective": "2024-10-31T01:00:00+01:00", "assignment": "2023-02-02T14:52:03+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 78591, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 33283", "ethics_committee": null, "edudract_number": null, "persons": [ "7369-78591-10" ] }, { "id": 6099, "title": { "de": "Nr4a1 als therapeutisches Target zu Behandlung von aggressiven Lymphomen", "en": "Investigating the potential of NR4A1 as therapeutic target for aggressive lymphomas " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-15T01:00:00+01:00", "begin_effective": "2020-03-15T01:00:00+01:00", "end_planned": "2022-07-31T02:00:00+02:00", "end_effective": "2023-06-30T02:00:00+02:00", "assignment": "2020-03-16T12:50:18+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 59183, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-51", "ethics_committee": null, "edudract_number": null, "persons": [ "6099-100134-12", "6099-59183-10", "6099-65239-12", "6099-79614-12", "6099-82501-12", "6099-51930-12", "6099-100510-12", "6099-111069-12", "6099-122590-12" ] }, { "id": 5987, "title": { "de": "Licht-vermittelte Kontrolle der TRPC3Funktion", "en": "Illuminating the TRPC3 signaling machinery" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-03-01T01:00:00+01:00", "end_planned": "2023-03-30T02:00:00+02:00", "end_effective": "2024-08-31T02:00:00+02:00", "assignment": "2019-12-09T11:13:45+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 78591, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P33263", "ethics_committee": null, "edudract_number": null, "persons": [ "5987-78591-10" ] }, { "id": 6260, "title": { "de": "Gehirnprotektion für sehr kleine Frühgeborene", "en": "Safeguarding the brain of our smallest children" }, "short": "SafeBoosC III", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-01T01:00:00+01:00", "begin_effective": "2020-03-01T01:00:00+01:00", "end_planned": "2022-02-28T01:00:00+01:00", "end_effective": "2022-04-30T02:00:00+02:00", "assignment": 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