Project List
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GET /v1/research/project/?format=api&offset=660&ordering=begin_planned
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=680&ordering=begin_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=640&ordering=begin_planned", "results": [ { "id": 3292, "title": { "de": "Leitbilder zur Gestaltung des Lebensendes Einstellungen zur Begleitung und Versorgung von Menschen am Lebensende und zur Hospizidee in der Steiermark", "en": "Attitudes toward end-of-life decisions and the hospice idea in Styria " }, "short": "Leitbilder zur Gestaltung des Lebensende", "url": "http://www.medunigraz.at/sozialmedizin/projekte/leitbilder_lebensende.html", "abstract": { "de": "Fragen der Gestaltung es Lebensendes sind europaweit zunehmend Gegenstand von öffentlichen Debatten sowie von politischen Initiativen. Es zeichnet sich in Europa jedoch kein einheitlicher Zugang zum Thema ab, sondern je nach nationaler Kultur und weltanschaulicher Prägung eines Landes entstehen variierende Leitbilder und institutionelle Lösungen.\r\n\r\nFür Österreich steht ein Reflexionsprozess zum Thema Gestaltung des Lebensendes bislang aus und es besteht daher die Gefahr, dass diese Leerstelle in der Zukunft durch einfache Übernahme von Leitbildern aus anderen Ländern gefüllt wird.\r\nAn dieser Stelle möchte das geplante Projekt die Grundlagen für eine eigenständige und innovative, der soziokulturellen Identität und den Traditionen des Landes entsprechende, Leitbildentwicklung schaffen.\r\n\t", "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2014-06-30T02:00:00+02:00", "end_effective": "2015-03-31T02:00:00+02:00", "assignment": "2013-05-29T11:50:24+02:00", "program": 75, "subprogram": null, "organization": 14024, "category": 10, "type": 10, "partner_function": 4, "manager": 51741, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3292-66488-12", "3292-51741-10" ] }, { "id": 3355, "title": { "de": "Schwangerschaftserkrankungen - Die Rolle von Metalloproteinasen und Endothelin ", "en": "The role of placental metalloproteinases in inflammation-associated pregnancy diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2015-03-31T02:00:00+02:00", "end_effective": "2014-07-31T02:00:00+02:00", "assignment": "2013-08-20T15:17:51+02:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3335, "title": { "de": "Development of micro medical analyzer for ammonia monitoring in expiratory gas of critically ill", "en": "Development of micro medical analyzer for ammonia monitoring in expiratory gas of critically ill" }, "short": "AMMSE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2016-03-31T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2013-07-17T10:58:16+02:00", "program": 105, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": 58323, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "840940", "ethics_committee": null, "edudract_number": null, "persons": [ "3335-58323-10" ] }, { "id": 3417, "title": { "de": "Die Rolle von NkG2D als Onkoprotein in der Krebsstammzelldifferenzierung", "en": "CO-OPTION OF THE NKG2D LYMPHOCYTE RECEPTOR AS AN ONCOPROTEIN PROMOTING CANCER STEM CELL TRANSDIFFERENTIATION AND CANCER AUTONOMY" }, "short": "NKG2D", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2016-03-31T02:00:00+02:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2013-11-04T14:01:39+01:00", "program": 24, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 60706, "contact": 60706, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "331255", "ethics_committee": null, "edudract_number": null, "persons": [ "3417-50777-12", "3417-60706-10" ] }, { "id": 3365, "title": { "de": "CONEKT-Kooperation, Vernetzung und Wissenstrasfer zwischen Österreich Kosovo und Albanien im Bereich Biobanking ", "en": "CONEKT-Cooperation, Networking and Knowhow Transfer between Austria, Kosovo, Albania in the field of biobanking" }, "short": "CONEKT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-08T02:00:00+02:00", "begin_effective": "2013-06-01T02:00:00+02:00", "end_planned": "2014-06-30T02:00:00+02:00", "end_effective": "2015-04-30T02:00:00+02:00", "assignment": "2013-09-03T12:37:32+02:00", "program": null, "subprogram": "HigherKOS", "organization": 28392, "category": 10, "type": 10, "partner_function": 4, "manager": 54033, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3365-54033-10" ] }, { "id": 3205, "title": { "de": "Analyse von RAS Mutationen in einem murinen in vivo Modell der akuten myeloischen Leukämie", "en": "Analysis of RAS mutations in a murine in vivo model of acute myeloid leukemia" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-15T02:00:00+02:00", "begin_effective": "2013-04-15T02:00:00+02:00", "end_planned": "2015-04-15T02:00:00+02:00", "end_effective": "2016-04-15T02:00:00+02:00", "assignment": "2013-03-08T14:51:46+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 57402, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 423 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3205-57402-10", "3205-77371-12", "3205-94596-12" ] }, { "id": 3320, "title": { "de": "Der Einfluss von perinatalen Parametern auf die zerebrale Oxygenierung von Neugeborenen am ersten Lebenstag", "en": "Influence of perinatal parameters on cerebral tissue oxygenation of newborn infants on the first day of life" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-05-01T02:00:00+02:00", "begin_effective": "2013-05-01T02:00:00+02:00", "end_planned": "2014-05-01T02:00:00+02:00", "end_effective": "2014-03-31T02:00:00+02:00", "assignment": "2013-07-09T16:27:55+02:00", "program": null, "subprogram": null, "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": 73733, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3320-73733-10" ] }, { "id": 3368, "title": { "de": "Auswirkung von Verkehrslärm im Freifeld", "en": "Evaluation of the influence of naturalistic road and rail traffic noise on both psychological and physiological parameters in the free field" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-05-01T02:00:00+02:00", "begin_effective": "2013-10-01T02:00:00+02:00", "end_planned": "2014-04-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2013-09-09T16:52:17+02:00", "program": 72, "subprogram": null, "organization": 14024, "category": 10, "type": 10, "partner_function": 2, "manager": 51845, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25747", "ethics_committee": null, "edudract_number": null, "persons": [ "3368-51845-10" ] }, { "id": 3315, "title": { "de": "The Voice of Rett", "en": "The Voice of Rett" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-05-01T02:00:00+02:00", "begin_effective": "2013-05-01T02:00:00+02:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2015-12-31T01:00:00+01:00", "assignment": "2013-07-05T10:12:30+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 58883, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3315-79651-11", "3315-58883-10" ] }, { "id": 3377, "title": { "de": "Pathophysiologie und Behandlung von Cholemischer Nephropathie", "en": "Pathophysiology and Treatment of Cholemic Nephropathy" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-06-01T02:00:00+02:00", "begin_effective": "2013-06-01T02:00:00+02:00", "end_planned": "2016-05-31T02:00:00+02:00", "end_effective": "2018-09-30T02:00:00+02:00", "assignment": "2013-09-19T11:45:29+02:00", "program": 72, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 52938, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25911", "ethics_committee": null, "edudract_number": null, "persons": [ "3377-50626-12", "3377-54247-12", "3377-57377-12", "3377-57596-12", "3377-66436-12", "3377-66467-12", "3377-70622-12", "3377-87214-12", "3377-53167-12", "3377-52938-10" ] }, { "id": 3222, "title": { "de": "GPR55 in der Entwicklung des Kolonkarzinoms", "en": "GPR55 in tumorigenesis and metastasis of colon cancer" }, "short": null, "url": null, "abstract": { "de": "GPR55 in der Entwicklung des Kolonkarzinoms\r\nG Protein gekoppelte Rezeptoren spielen eine wichtige Rolle im Tumorwachstum und in der Metastasierung von Krebszellen und stellen somit ein wichtiges pharmakologisches Target für die Krebstherapie dar. Auf Grund seiner fördernden Wirkung in der Proliferation und Invasion von Tumorzellen, aber auch in der Angiogenese, ist der G Protein gekoppelte Rezeptor 55 (GPR55) in jüngster Zeit als ein mögliches neues Target in Erscheinung getreten. Das bioaktive Phospholipid Lysophosphatidylinositol (LPI) ist seit längerem als der endogene Ligand des GPR55 Rezeptors bekannt. Erhöhte LPI Werte wurden im Ovarialkarzinom nachgewiesen und lassen auf einen Zusammenhang zwischen der LPI/GPR55 Achse und Krebswachstum schließen.\r\nGPR55 ist auch in Epithelzellen des Darmtrakts vorhanden, was auf eine mögliche Rolle in der Entwicklung des Kolonkarzinoms vermuten läßt. Im vorliegenden Projekt untersuchen wir die Funktion von GPR55 und LPI in der Tumorgenese und in der Metastasierung des Kolonkarzinoms zuerst an Hand der Kolonkarzinom Zelllinien HCT116 und SW480. Dabei werden Proliferations-, Apoptose-, Migration- und Invasionsassays verwendet ebenso wie molekularbiologische Methoden, um LPI-induzierte Signaltransduktionswege zu untersuchen. In einem Kolitis-assoziierten Kolonkarzinom Modell der Maus soll die Bedeutung von GPR55 in der Tumorentstehung in vivo untersucht werden, insbesondere ob GPR55 an der Proliferation von malignen Zellen und der Expression von onkogenen Transkriptionsfaktoren, wie NF-kappa B und STAT3, beteiligt ist. Die Rolle von GPR55 in der Verbreitung der Kolonkarzinomzellen in Sekundärorgane soll in einem in vivo Metastasierungsmodell untersucht werden. An Hand von histologischen Schnitten und Biopsien von humanem Kolonkarzinomgewebe wollen wir schließlich noch die Bedeutung von GPR55 und LPI in der Entstehung des Kolonkarzinoms beim Menschen untersuchen. Das Projekt sollte wesentliche Aussagen bezüglich einer möglichen pharmakologischen Therapie gegen Dickdarmkrebs basierend auf GPR55 geben. Weiters soll es eine Aussage liefern, ob LPI als möglicher Biomarker bei Dickdarmkrebs Verwendung finden könnte. \r\n", "en": null }, "begin_planned": "2013-06-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2016-05-31T02:00:00+02:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2013-03-26T10:24:55+01:00", "program": 72, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 56687, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25633", "ethics_committee": null, "edudract_number": null, "persons": [ "3222-56687-10" ] }, { "id": 3436, "title": { "de": "Quantitatives Modeling von Ca2+ Nanodomänen (QuMoCa)", "en": "Quantitative Modeling of Ca2+ Nanodomains" }, "short": "QuMoCa", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-06-01T02:00:00+02:00", "begin_effective": "2014-02-10T01:00:00+01:00", "end_planned": "2015-05-31T02:00:00+02:00", "end_effective": "2016-02-09T01:00:00+01:00", "assignment": "2013-11-19T11:43:39+01:00", "program": 24, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "330657", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5380, "title": { "de": "Progressionsbeurteilung bei metastasierenden neuroendokrinen Neoplasien (NEN) mit bildgebenden und biochemischen Verfahren", "en": "Evaluation of tumor progression in metastasised in neuroendocrine neoplasia (NEN) with biochemical and imaging techniques" }, "short": "Registerstudie", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-06-10T02:00:00+02:00", "begin_effective": "2017-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2027-12-31T01:00:00+01:00", "assignment": "2018-06-06T11:25:43+02:00", "program": null, "subprogram": "MEFOgraz", "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 65139, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-16", "ethics_committee": null, "edudract_number": null, "persons": [ "5380-65139-10" ] }, { "id": 3323, "title": { "de": "Gealterte T Zellen und Knochenabbau bei Rheumatoider Arthritis und Osteoporose ", "en": "T cells and bone loss in rheumatoid arthritis and primary osteoporosis" }, "short": "T cell senescence and bone loss", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-01T02:00:00+02:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2016-06-30T02:00:00+02:00", "end_effective": "2017-01-31T01:00:00+01:00", "assignment": "2013-07-10T10:43:13+02:00", "program": 79, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 66227, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3323-53560-12", "3323-78952-12", "3323-89855-12", "3323-66227-10" ] }, { "id": 3442, "title": { "de": "Evaluierung der Häufigkeit, Biologie und therapeutischer Relevanz von Fusionskinasen beim Melanom", "en": "Evaluating the frequency, biology, and therapeutic relevance of kinase fusions in melanoma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-01T02:00:00+02:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2015-06-30T02:00:00+02:00", "end_effective": "2016-06-30T02:00:00+02:00", "assignment": "2013-11-21T14:01:52+01:00", "program": 79, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3602, "title": { "de": "Imatinib als neues Prostaglandin freisetzendes Arzneimittel", "en": "Imatinib as a novel prostaglandin releasing drug" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-01T02:00:00+02:00", "begin_effective": "2014-04-01T02:00:00+02:00", "end_planned": "2016-07-01T02:00:00+02:00", "end_effective": "2019-09-30T02:00:00+02:00", "assignment": "2014-03-11T09:48:51+01:00", "program": 72, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 26185", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3337, "title": { "de": "Analyse des Darm-Mikrobioms bei affektiven Erkrankungen", "en": "Gut microbiome analyses in affective disorders" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-01T02:00:00+02:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2014-07-01T02:00:00+02:00", "end_effective": "2014-03-31T02:00:00+02:00", "assignment": "2013-07-18T16:33:48+02:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 54165, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3337-54165-10" ] }, { "id": 3433, "title": { "de": "Antibiotikaresistenz von E. coli von Spielplatzsandproben in Österreich", "en": "Antimicrobial resistance of E. coli isolates from playground sand in Austria" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-01T02:00:00+02:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2015-07-01T02:00:00+02:00", "end_effective": "2016-06-30T02:00:00+02:00", "assignment": "2013-11-15T13:50:51+01:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": 50521, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 895 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3433-50521-10" ] }, { "id": 3294, "title": { "de": "Spontaneous Movements at 3-5 Months Postterm Age: Are Sporadic Fidgety Movements of Clinical Relevance?", "en": "Spontaneous Movements at 3-5 Months Postterm Age: Are Sporadic Fidgety Movements of Clinical Relevance?" }, "short": "Sporadic Fidgety Movements", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-01T02:00:00+02:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2014-06-30T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2013-06-06T15:43:30+02:00", "program": 92, "subprogram": "EURASIA-PACIFIC UNINET ", "organization": 14010, "category": 10, "type": 10, "partner_function": 3, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3294-58883-11" ] }, { "id": 3312, "title": { "de": "Anti-atherosclerotic Effects of Ligustrazine", "en": "Anti-atherosclerotic Effects of Ligustrazine" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-07-28T02:00:00+02:00", "begin_effective": "2013-07-28T02:00:00+02:00", "end_planned": "2014-06-28T02:00:00+02:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2013-06-27T11:34:02+02:00", "program": 92, "subprogram": "Eurasia Pacific Uninet", "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 57932, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3312-57932-10" ] } ] }