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GET /v1/research/project/?format=api&offset=640&ordering=-begin_effective
{ "count": 2157, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=660&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=620&ordering=-begin_effective", "results": [ { "id": 6204, "title": { "de": "Der Einfluss pflanzlicher Ernährung auf die Immunmodulation. \r\nEffekte elektiver natürlicher Pflanzenfarbstoffe und der Lebensmittelmatrix auf die Aryl-Hydrocarbon-Rezeptor Aktivität.\r\n", "en": "The impact of plant-based nutrition on Immunmodulation.\r\nSubtitle: Effects of elective natural dyes and food matrix on aryl hydrocarbon receptor interaction.\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-07-01T02:00:00+02:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2020-11-30T01:00:00+01:00", "end_effective": "2022-06-30T02:00:00+02:00", "assignment": "2020-07-15T17:29:13+02:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": 88711, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-53", "ethics_committee": null, "edudract_number": null, "persons": [ "6204-88711-10" ] }, { "id": 6330, "title": { "de": "Optische Emissions-Spektroskopie an Gewebeproben", "en": "Optische Emissions-Spektroskopie an Gewebeproben" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-07-01T02:00:00+02:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2021-06-30T02:00:00+02:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2020-11-10T10:23:11+01:00", "program": null, "subprogram": null, "organization": 14112, "category": 10, "type": 10, "partner_function": 4, "manager": 52001, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6330-52001-10" ] }, { "id": 6235, "title": { "de": "High-Tech Akupunktur für die Prävention von lebensstilbedingten Erkrankungen - Eine 'Sino-Austrian' Kooperation - Fortsetzung 2019/2020", "en": "High-Tech Acupuncture for Prevention of Lifestyle Diseases - A Sino-Austrian Cooperation - Continuation 2019/2020" }, "short": "High-Tech Akupunktur und Lebensstil", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2020-01-31T01:00:00+01:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2020-08-10T10:38:22+02:00", "program": null, "subprogram": null, "organization": 14044, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 762 ], "funder_projectcode": "EPU 36/2019", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 6155, "title": { "de": "Identifizierung von Interaktionen akuter Leukämiezellen mit der Knochenmarksnische.", "en": "Identification of leukemic niche interactions in acute myeloid leukemia" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2022-03-31T02:00:00+02:00", "end_effective": "2025-06-30T02:00:00+02:00", "assignment": "2020-06-15T13:54:55+02:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 50747, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6155-50747-10" ] }, { "id": 6173, "title": { "de": "PROVIT-Metabolomics", "en": "PROVIT-Metabolomics" }, "short": "PROVIT-Metabolomics", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-06-19T02:00:00+02:00", "begin_effective": "2020-06-19T02:00:00+02:00", "end_planned": "2021-06-19T02:00:00+02:00", "end_effective": "2021-06-19T02:00:00+02:00", "assignment": "2020-06-29T13:34:32+02:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 1, "manager": 79771, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6173-79771-10" ] }, { "id": 5968, "title": { "de": "Multiskalenveränderungen im Knochen durch biologisch resorbierbare Implantate: Vorhersage der Struktur und der mechanischen Leistung", "en": "Multiscale changes in bone due to bio-resorbable implants: towards a\r\nprediction of structure and mechanical performance" }, "short": "SAXStomo", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-01T01:00:00+01:00", "begin_effective": "2020-06-01T02:00:00+02:00", "end_planned": "2023-02-28T01:00:00+01:00", "end_effective": "2024-05-31T02:00:00+02:00", "assignment": "2019-11-26T14:09:07+01:00", "program": 111, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": 50785, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I4409", "ethics_committee": null, "edudract_number": null, "persons": [ "5968-50785-10", "5968-96335-12", "5968-98087-12", "5968-107169-12", "5968-114967-12" ] }, { "id": 7370, "title": { "de": "Wechselwirkung von CRAC und Ca2+ aktivierten K+ Ionenkanälen", "en": "Interplay of CRAC channels with Ca2+ activated K+ channels" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-06-01T02:00:00+02:00", "end_planned": "2024-12-31T01:00:00+01:00", "end_effective": "2024-05-31T02:00:00+02:00", "assignment": "2023-02-02T14:57:40+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 78591, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P32851", "ethics_committee": null, "edudract_number": null, "persons": [ "7370-78591-10" ] }, { "id": 6353, "title": { "de": "Impact of UV on skin metabolome and lipidome", "en": "Impact of UV on skin metabolome and lipidome" }, "short": "UVmetabolome", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-06-01T02:00:00+02:00", "begin_effective": "2020-06-01T02:00:00+02:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2020-12-31T01:00:00+01:00", "assignment": "2020-12-02T17:11:59+01:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 87275, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6353-87275-10" ] }, { "id": 6133, "title": { "de": "Prozess analytische Technologien für industrielle Nanopartikel Produktionen", "en": "Process Analytical Technologies for Industrial Nanoparticles Production" }, "short": "NanoPAT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-02T01:00:00+01:00", "begin_effective": "2020-06-01T02:00:00+02:00", "end_planned": "2024-03-04T01:00:00+01:00", "end_effective": "2024-05-31T02:00:00+02:00", "assignment": "2020-05-13T12:52:37+02:00", "program": 109, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 86770, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6133-86770-10", "6133-100187-12", "6133-107594-12" ] }, { "id": 6214, "title": { "de": "Assoziation von ABH(O) und Lewis Blutgruppen Antigenen und COVID-19", "en": "Blood Groups in Infection and Host Susceptibility for COVID-19\r\n\r\n" }, "short": "BG und COVID-19", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-25T02:00:00+02:00", "begin_effective": "2020-06-01T02:00:00+02:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2020-12-31T01:00:00+01:00", "assignment": "2020-07-27T16:13:18+02:00", "program": null, "subprogram": null, "organization": 14058, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 6056, "title": { "de": "Entzündung und Stoffwechsel bei pulmonaler Hypertonie stehen im Zusammenhang mit der Inaktivierung des Chromosoms X: neue therapeutische Möglichkeiten", "en": "Inflammation and Metabolism in Pulmonary Hypertension are Linked to skewed chromosome X Inactivation: new therapeutic optiONS" }, "short": "IMPHLeXIONS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-05-04T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2024-06-30T02:00:00+02:00", "assignment": "2020-02-13T11:19:46+01:00", "program": 112, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 2, "manager": 62748, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I4651", "ethics_committee": null, "edudract_number": null, "persons": [ "6056-62748-10", "6056-96765-12" ] }, { "id": 6124, "title": { "de": "Geruchs- und Geschmackswahrnehmung bei bipolarer Störung ", "en": "Olfactory and gustatory perception in bipolar disorder" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-12-31T01:00:00+01:00", "assignment": "2020-04-28T17:09:43+02:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 2, "manager": 50654, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6124-50654-10", "6124-79454-12", "6124-79771-12", "6124-79733-12", "6124-90128-10", "6124-91818-12", "6124-86429-12", "6124-92607-12", "6124-95403-12" ] }, { "id": 6127, "title": { "de": "INNODIA HARVEST", "en": "INNODIA HARVEST" }, "short": "INNODIA HARVEST", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2023-04-30T02:00:00+02:00", "end_effective": "2024-04-30T02:00:00+02:00", "assignment": "2020-05-04T12:33:25+02:00", "program": 109, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 4, "manager": 51831, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": 1, "language": null, "funders": [ 10 ], "funder_projectcode": "945268", "ethics_committee": null, "edudract_number": null, "persons": [ "6127-51831-10", "6127-56667-12", "6127-90274-12", "6127-97867-12", "6127-81132-12", "6127-102575-12" ] }, { "id": 6476, "title": { "de": "Cell culture system for antiviral testing", "en": "Cell culture system for antiviral testing" }, "short": "WP 91011", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2021-03-03T15:30:32+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6476-51663-10" ] }, { "id": 6169, "title": { "de": "Etablierung von in virto Modellen für die Krebsfroschung", "en": "Establishing in vitro model for cancer research" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-05-31T02:00:00+02:00", "end_effective": "2021-10-31T02:00:00+02:00", "assignment": "2020-06-24T10:49:00+02:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 59183, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6169-51930-12", "6169-59183-10", "6169-79614-12", "6169-100134-12" ] }, { "id": 6408, "title": { "de": "Psychosoziale Auswirkungen der SARS-CoV-2 Pandemie auf MitarbeiterInnen der Landeskrankenhäuser in der Steiermark", "en": "Psychosocial consequences of SARS-CoV-2 on individuals working in hospitals in styria" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2021-01-13T11:49:13+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 50654, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6408-50654-10" ] }, { "id": 5941, "title": { "de": "Multiskalen-Modellierung von Herzklappenerkrankungen", "en": "Multiscale Modeling of Valvular Heart Diseases - Understanding the Mechanisms of Adverse Remodeling to Improve Precision Medicine." }, "short": "SICVALVES", "url": null, "abstract": { "de": "SICVALVES – Multiskalen-Modellierung von Herzklappenerkrankungen\r\n\r\nMotivation: Herzklappenerkrankungen sind eine zunehmende gesundheitliche Belastung für die alternde Bevölkerung, bei der allein die Aortenklappenstenose bei mehr als 12% der Patienten >70 Jahre vorherrscht. Es ist eine chronisch-progressive Erkrankung, die mit Geschlecht und Alter variiert. Bestehende Leitlinien für die Behandlungsplanung verwenden jedoch nur grobe Funktionsparameter, die die interindividuelle Variabilität nicht berücksichtigen und weit von den Anforderungen der Präzisionsmedizin entfernt sind. Im Zeitalter der digitalen Medizin haben Computermodelle das Potenzial, wichtige pathophysiologische Mechanismen zu entschlüsseln und zur personalisierten Präzisionsmedizin beizutragen.\r\nZiele: Die Nutzung fortgeschrittener Modelle auf Zell-, Gewebe- und Organebene, um mechanistische Erkenntnisse über Auslöser von ventrikulären Arrhythmien, diastolischer und systolischer Dysfunktion und myokardialen metabolischen Veränderungen zu gewinnen und zu untersuchen wie sich diese Prozesse gegenseitig verstärken. Geschlechtsspezifische Unterschiede müssen systematisch berücksichtigt werden. Letztlich sollen die Modelle zur Verbesserung der Diagnostik, Risikobewertung und Behandlungsplanung von Herzklappenerkrankungen beitragen.\r\nMethoden: Basierend auf unseren bisherigen Arbeiten werden wir bestehende computergestützte Modelle der Biomechanik, Elektrophysiologie und der Hämodynamik technologisch weiterentwickeln, testen und validieren. Zur Modellparametrisierung verwenden wir bestehende multidimensionale klinische Daten (Bildgebung, Sensortechnik, Systembiologie) aus eigenen früheren Untersuchungen bei Patienten mit Herzklappenerkrankungen. Die Validierung der Genauigkeit der Modelle zur Vorhersage von mechanistischen Veränderungen erfolgt anhand von Daten, die vor und nach dem Einsatz von künstlichen Klappenprothesen gewonnen werden.\r\nInnovation: Fortgeschrittene computergestützte Werkzeuge werden dafür genutzt, um personalisierte Modelle zu erstellen und diese zur quantitativen Bewertung von hypertropischem Remodeling und der Neigung zu Arrhythmien zu verwenden. Es werden vollständig neue Methoden entwickelt um zugrunde liegenden Mechanismen, Verlauf und Symptome die bei Herzklappenerkrankungen auftreten zu verstehen. Des Weiteren wird ein virtueller Simulator für die patientenspezifische Planung der Therapie von Herzklappenerkrankungen entwickelt, der die Wirksamkeit der künstlichen Klappenprothesen verbessert und die Sterblichkeit bei Patienten reduziert.", "en": "SICVALVES – Multiscale modeling of Valvular Heart Diseases\r\nUnderstanding the mechanisms of adverse remodeling to improve precision medicine\r\n\r\nBackground: Valvular Heart Diseases (VHD) are a detrimental health burden to the aging population where aortic valve stenosis alone has reached an incidence of more than 12% of patients >70y. It is a chronic-progressive disease that varies with gender and age. If left untreated, VHDs can cause malignant arrhythmias and severe heart failure. However, existing guidelines for treatment planning are using only rough function parameters that fail to account for inter-individual variability and are far away from the demands of precision medicine. In the age of digital medicine, computational modeling has the potential to unveil important pathophysiological mechanisms and to contribution towards personalized precision medicine.\r\nObjectives: To use advanced models of the cell, tissue, and organ level in VHD to gain mechanistic insights about triggers of ventricular arrhythmias, diastolic, and systolic dysfunction and myocardial metabolic alterations and how these processes reinforce each other. Gender differences will be systematically taken into account. Ultimately, models shall contribute to improve diagnostics, risk assessment, and treatment planning of VHDs.\r\nMethods: Based on our previous work, we will technologically advance, test, and validate existing computational models of biomechanics, electrophysiology, and hemodynamics. For model parameterization we use existing multidimensional clinical data (imaging, sensors, omics) from own previous research in patients with VHD (obtained before and after valve replacement). Validation of the model's accuracy to predict mechanistic changes will be done with data obtained before and after aortic valve replacement.\r\nInnovation: Advanced computational models will be leveraged to build personalized models and use these for quantitative assessment of hypertrophic remodeling and propensity for arrhythmias. Novel methodologies will be developed to understand important mechanisms of adverse remodeling in VHDs, as well as to improve patient care by optimizing patient selection and precision treatment planning in valve disease." }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2024-08-31T02:00:00+02:00", "assignment": "2019-10-28T13:38:14+01:00", "program": 112, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 79791, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I4652", "ethics_committee": null, "edudract_number": null, "persons": [ "5941-79791-10", "5941-122514-12", "5941-91352-12", "5941-119147-12" ] }, { "id": 6426, "title": { "de": "MicroMOOD", "en": "MicroMOOD" }, "short": "MicroMOOD", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2021-04-01T02:00:00+02:00", "end_effective": "2022-12-31T01:00:00+01:00", "assignment": "2021-01-26T18:49:05+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 3, "manager": 99972, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6426-99972-10" ] }, { "id": 6100, "title": { "de": "In-vitro Verifikation von Virus-Inhibitoren", "en": "In-vitro verification of virus inhibitors" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-16T01:00:00+01:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2020-09-30T02:00:00+02:00", "end_effective": "2020-10-31T01:00:00+01:00", "assignment": "2020-03-16T13:55:16+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-50", "ethics_committee": null, "edudract_number": null, "persons": [ "6100-51663-10" ] }, { "id": 6383, "title": { "de": "Assoziation von ABH(O) und Lewis Blutgruppen Antigenen und COVID- 19: eine retrospektive Studie.", "en": "Blood Groups in Infection and Host Susceptibility for COVID-19: a retrospective study." }, "short": "ABO und COVID-19", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2021-04-01T02:00:00+02:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2020-12-21T11:50:01+01:00", "program": null, "subprogram": null, "organization": 14058, "category": 10, "type": 10, "partner_function": 4, "manager": 51964, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6383-51964-10" ] } ] }