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GET /v1/research/project/?format=api&offset=620&ordering=-end_planned
{ "count": 2245, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=640&ordering=-end_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=600&ordering=-end_planned", "results": [ { "id": 7907, "title": { "de": "Untersuchung seltener und häufiger genetischer Varianten und spezifischer Merkmale der COPD-assoziierten pulmonalen Hypertonie", "en": "Assessment of rare and common genetic variants and specific traits of COPD-associated pulmonary hypertension" }, "short": "Mid-Career Grant der ÖGP 2023", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-07T01:00:00+01:00", "begin_effective": "2023-11-07T01:00:00+01:00", "end_planned": "2024-11-07T01:00:00+01:00", "end_effective": "2024-11-07T01:00:00+01:00", "assignment": "2023-11-29T08:21:55+01:00", "program": null, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 4, "manager": 87980, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2396 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7907-87980-10" ] }, { "id": 7698, "title": { "de": "Erforschung eines mechanistischen Stoffwechselweges, welcher ein potentieller Auslöser für IUGR ist.", "en": "Investigation of a mechanistic metabolic pathway, potentially contributing IUGR " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-09-01T02:00:00+02:00", "begin_effective": "2023-08-01T02:00:00+02:00", "end_planned": "2024-11-01T01:00:00+01:00", "end_effective": "2024-10-01T02:00:00+02:00", "assignment": "2023-07-28T13:06:02+02:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 82600, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7698-82600-10" ] }, { "id": 7574, "title": { "de": "Smarte Aktivierung zur Verbesserung Kognitiver Leistungsfähigkeit durch\r\nEntscheidungsassistenz und Digitale Biomarker", "en": "Smart activation to improve cognitive functions through decision support and digital biomarker" }, "short": "SmartAktiv", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-04-01T02:00:00+02:00", "begin_effective": "2023-04-17T02:00:00+02:00", "end_planned": "2024-11-01T01:00:00+01:00", "end_effective": "2025-03-16T01:00:00+01:00", "assignment": "2023-05-17T16:17:36+02:00", "program": 126, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 2, "manager": 59566, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": 3, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999904045", "ethics_committee": null, "edudract_number": null, "persons": [ "7574-59566-10" ] }, { "id": 7031, "title": { "de": "Identifizierung von antigen-spezifischen T-Zellen über Ca2+-NFAT Signalweg in nicht-kleinzelligen Lungenkrebs", "en": "Identification of antigen-specific T cells via Ca2+-NFAT signaling in non-small celllung cancer" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-11-01T01:00:00+01:00", "begin_effective": "2022-07-01T02:00:00+02:00", "end_planned": "2024-11-01T01:00:00+01:00", "end_effective": "2024-06-30T02:00:00+02:00", "assignment": "2022-05-23T11:06:58+02:00", "program": 116, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 1, "manager": 98567, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 15 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7031-98567-10" ] }, { "id": 7347, "title": { "de": "Mutations-spezifische Eradikation von Myelofibrose mittels Genom-editierter humaner Stammzellen", "en": "Engineered human stem cells for mutation-specific eradication of myelofibrosis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-11-01T01:00:00+01:00", "begin_effective": "2021-11-01T01:00:00+01:00", "end_planned": "2024-10-31T01:00:00+01:00", "end_effective": "2024-10-31T01:00:00+01:00", "assignment": "2023-01-25T10:34:34+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 2, "manager": 50747, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2647 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7347-50747-10" ] }, { "id": 6899, "title": { "de": "Wir alle sind Mischwesen: Mikrochimärsimus, Gesundheit und Evolution", "en": "We All Are Multitudes: the Microchimerism, Human Health and Evolution" }, "short": "Microchimerism and Evolution", "url": "https://www.microchimerism.info/", "abstract": { "de": "Mikrochimärismus (MC) beschreibt die Existenz einer kleinen Anzahl fremder menschlicher Zellen in einer Person. Dieses Phänomen entsteht unter anderem während der Schwangerschaft durch das Wandern von Zellen zwischen Mutter und Fötus. Das derzeitige Wissen um MC ist unvollständig und teils widersprüchlich, über die Rolle, die mikrochimäre Zellen in der Wirtsphysiologie spielen, ist wenig bekannt.\r\nWas ist der Grund der anscheinend paradoxen Effekte von MC? Welche Mechanismen sind beteiligt oder sogar verantwortlich dafür, dass mikrochimäre Zellen ins Wirtsgewebe wandern, sich dort integrieren und oftmals ein Wirtsleben lang verbleiben? Die Evolutionsbiologie und die maternal-fetale Konflikttheorie können einen Rahmen bieten, um die Persistenz mikrochimärer Zellen zu verstehen und deren Existenz mit einer erhöhten Anfälligkeit für Krankheiten zu verknüpfen.\r\nWir gehen zunächst davon aus, dass MC weiter verbreitet ist als bisher berichtet. Wir nehmen weiters an, dass mikrochimäre Zellen eine adaptive Rolle in der Physiologie des Wirts zu spielen vermögen und Vorteile für Mütter und Nachkommen bieten können, etwa durch Übertragung von Stammzellen und anderen Zelltypen aber auch durch Übertragung von wichtigen Komponenten des und Signalen für das Immunsystem. Jedoch werden sich in manchen Geweben die maternal-fötalen genetischen Interessen nicht zur Deckung bringen lassen, was eine erhöhte Anfälligkeit für Krankheiten zur Folge haben kann. Daher ist es unser Ziel, den Einfluss des MC auf Gesundheit und Krankheit zu studieren und Potential und Effekte des Zelltransfers über Generationengrenzen hinweg zu verstehen.\r\nBasis unseres Projekts ist die Verwendung modernster Technologien zur Analyse des bidirektionalen Transfers mikrochimärer Zellen zwischen Individuen und die Verteilung der mikrochimären Zellen in den Zielgeweben. Weiters widmen wir uns den Effekten, die aus der Interaktion von mikrochimären Zellen und dem Immunsystem des Wirts hervorgehen. Diese Themen studieren wir in mehreren Teilprojekten: Erstellung eines Maus-Mikrochiom-Atlas (Projekt 1), Phänotypisierung von maternalem (Projekt 2) und fetalem (Projekt 3) MC, Charakterisierung von mikrochimären Zellen in plazentanahen, -fernen Geweben und diversen Organen (Projekt 4) sowie den Zusammenhang von MC und Autoimmunerkrankung im Tiermodell (Projekt 5).\r\nUnsere Forschung dient dem Verständnis der Interaktion von mikrochimären Zellen mit dem Wirt und zur Klärung der Fragen, wie die Toleranz von MC während der Schwangerschaft und postpartum bei Müttern gewährleistet und aufrecht erhalten werden kann, welche Auswirkungen MC auf die frühe Entwicklung von Föten hat und ob es während Krankheiten zum Zusammenbruch der Immuntoleranz kommt und welche Ursachen dies hat.", "en": "Microchimerism (MC) is the harboring of a small number of cells between two distinct individuals. This transfer of cells is well known to occur between mothers and offspring during gestation, though other avenues of transfer may be possible. The current understanding of MC is puzzling and little is known about the role microchimeric cells play in host physiology.\r\nWhy are the effects of MC paradoxical and what are the mechanisms responsible for maintaining microchimeric cells over an organism’s lifetime? Evolutionary biology and maternal-fetal conflict theory can provide a framework to understand the persistence of microchimeric cells, and how this may lead to disease vulnerability.\r\nWe hypothesize MC is much more common than previously reported and microchimeric cells play an adaptive role in host physiology, providing benefits for both mothers and offspring through transfers of stem and other cell types, and providing key immune system components and signals. However, in certain host tissues the maternal-fetal genetic interests may not align, potentially leading to disease vulnerability.\r\nWe aim to understand the role MC plays in health and disease, and understand the potential for and effects of subsequent generational transfers of microchimeric cells. We will use cutting edge technology to characterize MC cell distribution and trafficking between hosts and the effects of MC-host immune system interactions in various host tissues by creating a mouse Microchiome Atlas (Project 1), phenotyping human maternal MC (mMC) (Project 2), phenotyping human fetal MC (fMC) (Project 3), phenotyping microchimeric cells proximal and distal in terms of distance from the maternal-fetal interface as well as in various other organs (Project 4), and interrogating the context of MC and autoimmune disease in animal models (Project 5).\r\nOur research will determine how microchimeric cells interact with the host system to initiate and maintain tolerance of MC during pregnancy, the postpartum period for mothers and early development in offspring, and uncover if there is a breakdown in immune tolerance during disease states, and what causes it." }, "begin_planned": "2022-02-01T01:00:00+01:00", "begin_effective": "2021-12-01T01:00:00+01:00", "end_planned": "2024-10-31T01:00:00+01:00", "end_effective": "2026-08-30T02:00:00+02:00", "assignment": "2022-02-01T12:59:33+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 3, "manager": 54171, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2575 ], "funder_projectcode": "62214", "ethics_committee": null, "edudract_number": null, "persons": [ "6899-104057-12", "6899-54171-10", "6899-82600-12", "6899-104139-12", "6899-114270-12", "6899-115382-12", "6899-116463-12" ] }, { "id": 6001, "title": { "de": "Das Darm-Mikrobiom im Verlauf hämato-/onkologischer Erkrankungen", "en": "The Gut Microbiome in Haemato-/Oncological Patients" }, "short": "MikroPHiOm", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-11-01T01:00:00+01:00", "begin_effective": "2019-11-01T01:00:00+01:00", "end_planned": "2024-10-31T01:00:00+01:00", "end_effective": "2024-10-31T01:00:00+01:00", "assignment": "2019-12-16T10:01:50+01:00", "program": null, "subprogram": null, "organization": 14095, "category": 10, "type": 10, "partner_function": 4, "manager": 56810, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6001-56810-10" ] }, { "id": 5343, "title": { "de": "CD Labor für Gas- und Partikeltransport durch Papier", "en": "CD Laboratory for Gas and Particle Transport through Paper" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-01T02:00:00+02:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2024-10-31T01:00:00+01:00", "end_effective": "2024-12-31T01:00:00+01:00", "assignment": "2018-04-16T11:35:10+02:00", "program": 97, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 54018, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 23 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5343-54018-10" ] }, { "id": 7854, "title": { "de": "LichtAktive MikroPartikel (LAMP) zur Wiederherstellung der Sehfunktion bei \r\nNetzhautdegeneration", "en": "Light Active MicroParticles for vision restoration in retina degenerative diseases" }, "short": "LAMP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2024-10-30T01:00:00+01:00", "end_effective": "2025-04-30T02:00:00+02:00", "assignment": "2023-10-25T14:05:31+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 99325, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7854-99325-10", "7854-114030-12" ] }, { "id": 7773, "title": { "de": "Entwicklung einer App zur Bewertung sowie Quantifizierung des Schweregrads idiopathischer epiretinaler Membranen und Vorschlag eines Punktesystems zur weiteren Therapiegliederung: eine prospektive Pilotstudie ", "en": "Developing an App to assess and quantify idiopathic epiretinal membrane severity and proposing a scoring system for further treatment recommendation: a prospective pilot study" }, "short": "ERM APP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-10T02:00:00+02:00", "begin_effective": "2023-10-01T02:00:00+02:00", "end_planned": "2024-10-10T02:00:00+02:00", "end_effective": "2024-09-30T02:00:00+02:00", "assignment": "2023-09-19T12:46:56+02:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 4, "manager": 104906, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938, 2194 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7773-104906-10" ] }, { "id": 7818, "title": { "de": "Oxidativer Stress vor und nach probiotischer Therapie bei Depression", "en": "Oxidative Stress pre- and post probiotic therapy in major depression" }, "short": "OXSTRESS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-05T02:00:00+02:00", "begin_effective": "2023-10-05T02:00:00+02:00", "end_planned": "2024-10-05T02:00:00+02:00", "end_effective": "2024-10-05T02:00:00+02:00", "assignment": "2023-10-09T16:03:03+02:00", "program": null, "subprogram": null, "organization": 29447, "category": 10, "type": 10, "partner_function": 4, "manager": 84449, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7818-84449-10" ] }, { "id": 6505, "title": { "de": "Perinatales sowie neurologisches 2-Jahres Outcome bei Kindern mit später Wachstumsrestriktion: randomisiert kontrollierte TRUFFLE-2 Studie (Österreichischer Teil der Studie)", "en": "Perinatal and 2-year neurodevelopmental outcome in late preterm fetal compromise: the TRUFFLE-2 randomized, controlled trial (Austrian part of the study)" }, "short": "TRUFFLE-2 Austria", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-10-01T02:00:00+02:00", "begin_effective": "2020-10-01T02:00:00+02:00", "end_planned": "2024-10-01T02:00:00+02:00", "end_effective": "2027-04-30T02:00:00+02:00", "assignment": "2021-03-23T15:15:49+01:00", "program": 108, "subprogram": null, "organization": 14064, "category": 10, "type": 10, "partner_function": 3, "manager": 50155, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI881", "ethics_committee": "32-237 ex 19/20", "edudract_number": null, "persons": [ "6505-50155-10" ] }, { "id": 8054, "title": { "de": "Ernährungsgewohnheiten von Patient*innen mit \r\nchronisch-entzündlichen Darmerkrankungen \r\nin Österreich und Deutschland", "en": "Diet and Nutrition among patients with inflammatory bowel disease in Austria and Germany" }, "short": "Nutrition IBD Study", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2024-10-01T02:00:00+02:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-02-21T10:50:23+01:00", "program": null, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 3, "manager": 53167, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 203 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8054-74515-12", "8054-53167-10", "8054-53167-12" ] }, { "id": 6714, "title": { "de": "RESPIMMUN: Charakterisierung des vaskulären Phänotyps bei COPD. Gib es Geschlechtsunterschiede?", "en": "RESPIMMUN: Characterization of the vascular phenotype in COPD. Are there gender differences?" }, "short": "RESPIMMUN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2021-10-01T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2021-09-28T17:16:31+02:00", "program": 66, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 2, "manager": 54345, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "DOC 129-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6714-101018-12", "6714-105621-12", "6714-111570-12" ] }, { "id": 6718, "title": { "de": "Funktion von plazentaren extrazellulären Vesikeln im Stoffwechsel des Feten ", "en": "Role of placental extracellular vesicles in fetal metabolism" }, "short": "Land Stmk docfunds DP-iDP Zusatzfin.", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2022-03-01T01:00:00+01:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2025-02-28T01:00:00+01:00", "assignment": "2021-09-30T15:08:30+02:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": 50442, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6718-50442-10" ] }, { "id": 7182, "title": { "de": "Vereinfachung medizinischer Befunde mit Hilfe von künstlicher Intelligenz.", "en": "Simplification of medical reports using Artificial Intelligence." }, "short": "SimplifAI", "url": null, "abstract": { "de": "In den letzten Jahren hat sich in der medizinischen Landschaft ein Trend hin zu einer wertorientierten Gesundheitsversorgung abgezeichnet. Diese zielt darauf ab, die bestmöglichen Behandlungsergebnisse oder die bestmögliche Versorgung zu den niedrigsten Kosten zu erreichen [Porter, 2010]. Studien haben gezeigt, dass Patienten, die ihren Gesundheitszustand besser verstehen, eine höhere Therapieakzeptanz und einen besseren Heilungsverlauf aufweisen. Gut informierte und eigenverantwortliche Patienten spielen daher eine Schlüsselrolle in einem modernen patientenzentrierten Gesundheitssystem.\r\nWesentliche Informationen über eine Krankheit und die entsprechende Therapie werden in einem medizinischen Patientenbericht festgehalten. Dieser Bericht dient den behandelnden Ärzten zur Dokumentation des Zustands des Patienten und dem Informationsaustausch mit anderen Ärzten. Im Allgemeinem ist ein Patientenbericht nicht dazu gedacht, dem Patienten Informationen zu vermitteln, weshalb eine hochspezialisierte medizinische Fachsprache verwendet wird. Um dem Patienten relevante Informationen zu übermitteln, ist ein Patientengespräch üblich. Die Qualität der Informationsübermittlung hängt von den Kommunikationsfähigkeiten des Arztes und des Patienten, der für das Gespräch zur Verfügung stehenden Zeit und dem psychischen Zustand des Patienten ab.\r\nDie Verfügbarkeit elektronischer Gesundheitsakten (EHR) und das Aufkommen von Deep Learning (DL)-Technologien in der Sprachverarbeitung (NLP) ermöglichen eine semantische Analyse, um komplexe Inhalte in eine, für Patienten leicht verständliche Sprache zu übersetzen. Vor allem im deutschsprachigen, medizinischen Bereich sind DL-Techniken, aufgrund des Mangels an frei zugänglichen Daten, nicht einsetzbar. Dies ist vor allem auf strenge Datenschutzbestimmungen zurückzuführen. Ziel dieses Projekts ist die Vereinfachung deutschsprachiger klinischer Befunde mit Fokus Radiologie, um Patienten eine aktivere Rolle beim Management ihrer Gesundheit zu ermöglichen.\r\nAbseits von radiologischen Befunden ist es wichtig, das Schema für die Extraktion von medizinischen Entitäten und deren Beziehungen zueinander auf andere medizinische Bereiche auszuweiten. Für die Generierung eines heterogenen, annotierten, medizinischen Datensatzes ist die Einbindung von Expertenwissen unabdingbar. Um den Aufwand für manuelles Labeling so gering wie möglich zu halten, ist die Entwicklung einer neuartigen, einfach zu bedienenden Open-Source-Applikation ein weiterer wesentlicher Punkt in diesem Projekt.\r\nEin weiteres wichtiges Ziel ist die Analyse, inwieweit vereinfachte medizinische Befunde Patienten in einem realen Szenario zur Verfügung gestellt werden können sowie die Akzeptanz diese Befunde. Zukünftig sollen einerseits bestehende Gesundheitsdienstleister mit dieser Technologie ausgerüstet werden und andererseits Patienten in der Lage sein, über eine Webanwendung ihre medizinischen Befunde selbständig übersetzen zu lassen.\r\n", "en": "In recent years, there has been a trend in the medical landscape toward value-based healthcare. Value-based healthcare strives to achieve the best possible health outcomes or the best possible care at the lowest cost [Porter, 2010]. Studies proved that patients that better understand their health status have higher treatment compliance and a better outcome. Hence, well-informed and empowered patients play a key role in a modern patient-centered healthcare system.\r\nThe necessary information about a disease and the appropriate therapy is recorded in a medical patient report. This report is used to document the patient's state by treating physicians and to exchange information between physicians involved in the patient’s therapy. Originally, a patient report is not intended to provide information to the patient, so highly specialized medical language is used. To convey relevant information to the patient, a verbal conversation is the usual way. The quality of this information transfer is related to the doctor’s and patient’s communication skills, the time available for the conversation and the mental state of the patient, making this process highly user-dependent.\r\nThe availability of electronic health records (EHR) and the advent of Deep Learning (DL) technologies in natural language processing (NLP) now enable a semantic analysis to translate relevant content into language that medical laypeople can understand. Especially in the healthcare and clinical domain, DL techniques are rarely used as they lack available open data, which is mainly due to privacy concerns. This is even worse for German-language clinical data. In this project, we want to overcome these issues and apply text simplification for German-language clinical reports with a special focus on radiological reports to empower patients to take a more active role in managing their health.\r\nTo go beyond radiology reports, it is essential to extend the schema for medical entity and relation extraction to other medical fields. The generation of a large annotated medical corpus has to be supported by expert knowledge. To keep manual annotation costs as low as possible, the development of a novel easy to use, multiuser open-source annotation framework for human annotators is another goal of this project. It is important for this project to demonstrate the feasibility of report simplification in a real-world scenario. We are aiming to support existing healthcare providers with this technology, as well as enable patients to autonomously upload and analyze their medical reports independently.\r\n" }, "begin_planned": "2022-10-01T02:00:00+02:00", "begin_effective": "2022-10-01T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2025-02-07T01:00:00+01:00", "assignment": "2022-09-26T15:49:59+02:00", "program": 126, "subprogram": null, "organization": 14054, "category": 10, "type": 10, "partner_function": 3, "manager": 57389, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "894729", "ethics_committee": null, "edudract_number": null, "persons": [ "7182-57389-10", "7182-62787-12" ] }, { "id": 7044, "title": { "de": "Neprilysin in der Schwangerschaft", "en": "Neprilysin in pregnancy" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2022-10-01T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2027-03-31T02:00:00+02:00", "assignment": "2022-06-07T13:42:34+02:00", "program": 108, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": 50674, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI1023", "ethics_committee": null, "edudract_number": null, "persons": [ "7044-50674-10", "7044-61680-12", "7044-109541-12", "7044-100010-12", "7044-104465-12", "7044-100803-12", "7044-117721-12", "7044-122576-12", "7044-128675-12" ] }, { "id": 5271, "title": { "de": "Liquid Biopsies for early Detection of Cancer - Modul 1 Investigation of size distribution, origin and dynamics of plasma DNA", "en": "Liquid Biopsies for early Detection of Cancer - Modul 1 Investigation of size distribution, origin and dynamics of plasma DNA" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-01T02:00:00+02:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2024-09-30T02:00:00+02:00", "assignment": "2018-02-16T13:26:49+01:00", "program": 97, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 4, "manager": 50899, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 23 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5271-50899-10" ] }, { "id": 6217, "title": { "de": "Therapeutisches Potenzial von AMPs bei atopischer Dermatitis", "en": "Therapeutic potential of antimicrobial peptides in atopic dermatitis " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-10-01T02:00:00+02:00", "begin_effective": "2020-10-01T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2020-07-30T11:25:38+02:00", "program": 111, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 3, "manager": 51618, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I4939", "ethics_committee": null, "edudract_number": null, "persons": [ "6217-54011-12", "6217-84167-12", "6217-87275-12", "6217-87663-12", "6217-88082-12", "6217-98990-12", "6217-51618-10", "6217-107955-12", "6217-108412-12", "6217-108816-12", "6217-118468-12" ] }, { "id": 7637, "title": { "de": "Smarte Aktivierung zur Verbesserung Kognitiver Leistungsfähigkeit durch Entscheidungsassistenz und Digitale Biomarker", "en": "Smart activation to improve cognitive performance through decision assistance and digital biomarkers" }, "short": "SmartAktiv", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-02-01T01:00:00+01:00", "begin_effective": "2023-04-17T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2025-03-16T01:00:00+01:00", "assignment": "2023-06-21T12:40:26+02:00", "program": 126, "subprogram": null, "organization": 14024, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999904045", "ethics_committee": null, "edudract_number": null, "persons": [ "7637-119651-12" ] } ] }