Project List
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GET /v1/research/project/?format=api&offset=460&ordering=-begin_planned
{ "count": 2244, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=480&ordering=-begin_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=440&ordering=-begin_planned", "results": [ { "id": 8077, "title": { "de": "Smart FOX - Smart and Federated Open Data eXchange of citizen-based data donations for clinical research", "en": "Smart FOX - Smart and Federated Open Data eXchange of citizen-based data donations for clinical research" }, "short": "Smart FOX", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-12-01T01:00:00+01:00", "begin_effective": "2024-07-01T02:00:00+02:00", "end_planned": "2025-11-30T01:00:00+01:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2024-03-08T10:12:02+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8077-51663-10" ] }, { "id": 7988, "title": { "de": "Endocannabinoidsystem und Tumorstroma", "en": "The endocannabinoid system of the tumor stroma" }, "short": "Endocannabinoid system_tumor stroma", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-12-01T01:00:00+01:00", "begin_effective": "2024-02-20T01:00:00+01:00", "end_planned": "2027-11-30T01:00:00+01:00", "end_effective": "2028-02-19T01:00:00+01:00", "assignment": "2024-01-22T14:40:32+01:00", "program": 72, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 56687, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PAT4791123", "ethics_committee": null, "edudract_number": null, "persons": [ "7988-56687-10" ] }, { "id": 7907, "title": { "de": "Untersuchung seltener und häufiger genetischer Varianten und spezifischer Merkmale der COPD-assoziierten pulmonalen Hypertonie", "en": "Assessment of rare and common genetic variants and specific traits of COPD-associated pulmonary hypertension" }, "short": "Mid-Career Grant der ÖGP 2023", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-07T01:00:00+01:00", "begin_effective": "2023-11-07T01:00:00+01:00", "end_planned": "2024-11-07T01:00:00+01:00", "end_effective": "2024-11-07T01:00:00+01:00", "assignment": "2023-11-29T08:21:55+01:00", "program": null, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 4, "manager": 87980, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2396 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7907-87980-10" ] }, { "id": 7854, "title": { "de": "LichtAktive MikroPartikel (LAMP) zur Wiederherstellung der Sehfunktion bei \r\nNetzhautdegeneration", "en": "Light Active MicroParticles for vision restoration in retina degenerative diseases" }, "short": "LAMP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2024-10-30T01:00:00+01:00", "end_effective": "2025-04-30T02:00:00+02:00", "assignment": "2023-10-25T14:05:31+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 99325, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7854-99325-10", "7854-114030-12" ] }, { "id": 7959, "title": { "de": "Zusammensetzung und Funktion von Immunzellen bei Patient*innen mit und ohne steroidrefraktärer akuter und chronischer Graft-versus-Host-Krankheit nach allogener hämatopoetischer Zelltransplantation", "en": "Immune cell composition and function in patients with and without steroid-refractory acute and chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation" }, "short": "Immune cell composition in GVHD", "url": null, "abstract": { "de": null, "en": "One of the most serious life-threatening complications of allogeneic hematopoietic stem cell transplantation (allo-HCT) is acute and chronic graft-versus-host disease (GVHD). (1,2) The established first-line therapy of acute GVHD is methylprednisolone with an initial dose of 2 mg/kg body weight per day. But, only half of all patients respond to first-line therapy and the so-called steroid-refractory GVHD (SR-GVHD) is associated with a poor long-term prognosis. There is still an urgent need for biomarkers that predict response to glucocorticoid therapy. In a retrospective study we showed that cellular infiltrates of immune cells, like innate lymphoid cells (ILCs) and tissue-resident memory T cells (TRMs), differ at onset of gastrointestinal (GI) GVHD in patients who subsequently respond to glucocorticoid therapy compared to patients developing steroid-refractory disease. Based on these preliminary data, we hypothesize that GVHD affects the composition of immune cell populations in affected tissues, such as skin and GI tract, and cellular and molecular profiles of immune cells from peripheral blood (PB) and tissue biopsies, as well as the GI microbiome, may predict lack of response to glucocorticoid therapy. Furthermore, these cellular and molecular profiles may be prognostic for immune reconstitution after allo-HCT. Therefore, the aim of this study is to identify cellular and molecular profiles of GVHD in patients. \r\nFor this purpose, we will prospectively collect clinical data of patients undergoing allo-HCT at the Clinical Division of Hematology at the Medical University/University Hospital Graz, to create a database and compare patient’s clinical course with immune cell composition as well as function/activation state of the PB determined by flow cytometry and cytokine production, as we GI microbiome analysis and tissue samples (skin and GI) obtained from routine clinical biopsies using immunofluorescence, immunohistochemistry and High-Definition Spatial Transcriptomics (HDST). Results of blood and tissue immune cell analyses, cytokines and data from GI microbiome will be compared to the cli nical data on occurrence and severity of GVHD, response to GVHD therapy and patient outcome.\r\n" }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-01-04T15:27:07+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 82501, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894, 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7959-100134-12", "7959-59183-12", "7959-82501-10", "7959-111069-12" ] }, { "id": 7935, "title": { "de": "European action for the Diagnosis of Early Non-symptomatic Type 1 diabetes For Intervention", "en": "European action for the Diagnosis of Early Non-symptomatic Type 1 diabetes For Intervention" }, "short": "EDENT1FI", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2023-11-01T01:00:00+01:00", "end_planned": "2028-10-31T01:00:00+01:00", "end_effective": "2028-10-31T01:00:00+01:00", "assignment": "2023-12-15T12:09:06+01:00", "program": 211, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 2, "manager": 51831, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "GA101132379", "ethics_committee": null, "edudract_number": null, "persons": [ "7935-51831-10", "7935-50452-12", "7935-56667-12", "7935-81132-12", "7935-90274-12", "7935-97867-12", "7935-102575-12", "7935-109149-12" ] }, { "id": 8109, "title": { "de": "New AntiVirals for Infections with Pandemic Potential", "en": "New AntiVirals for Infections with Pandemic Potential" }, "short": "NAVIPP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2028-10-31T01:00:00+01:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-03-22T10:42:25+01:00", "program": 211, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8109-51663-10" ] }, { "id": 8021, "title": { "de": "Teaching critical thinking in science through nanolearning and virtual exchange principles", "en": "Teaching critical thinking in science through nanolearning and virtual exchange principles" }, "short": " NANO-THINK ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-02-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2024-02-05T13:49:53+01:00", "program": 220, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 2, "manager": 57932, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8021-57932-10" ] }, { "id": 8027, "title": { "de": "Personalisierte zielgerichtete Behandlung des Glioblastom mittels ex-vivo Medikamenten Screening: \"Advanced brain Tumour TheRApy Clinical Trial (ATTRACT)\" ", "en": "Personalized targeted glioblastoma therapies by ex vivo drug \r\nscreening: Advanced brain Tumour TheRApy Clinical Trial (ATTRACT) " }, "short": "ATTRACT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-15T02:00:00+02:00", "begin_effective": "2023-10-01T02:00:00+02:00", "end_planned": "2031-10-01T02:00:00+02:00", "end_effective": "2027-09-30T02:00:00+02:00", "assignment": "2024-02-06T14:09:11+01:00", "program": null, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 1, "manager": 59316, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2963 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8027-59316-10", "8027-56667-12", "8027-66435-12" ] }, { "id": 7773, "title": { "de": "Entwicklung einer App zur Bewertung sowie Quantifizierung des Schweregrads idiopathischer epiretinaler Membranen und Vorschlag eines Punktesystems zur weiteren Therapiegliederung: eine prospektive Pilotstudie ", "en": "Developing an App to assess and quantify idiopathic epiretinal membrane severity and proposing a scoring system for further treatment recommendation: a prospective pilot study" }, "short": "ERM APP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-10T02:00:00+02:00", "begin_effective": "2023-10-01T02:00:00+02:00", "end_planned": "2024-10-10T02:00:00+02:00", "end_effective": "2024-09-30T02:00:00+02:00", "assignment": "2023-09-19T12:46:56+02:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 4, "manager": 104906, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938, 2194 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7773-104906-10" ] }, { "id": 7818, "title": { "de": "Oxidativer Stress vor und nach probiotischer Therapie bei Depression", "en": "Oxidative Stress pre- and post probiotic therapy in major depression" }, "short": "OXSTRESS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-05T02:00:00+02:00", "begin_effective": "2023-10-05T02:00:00+02:00", "end_planned": "2024-10-05T02:00:00+02:00", "end_effective": "2024-10-05T02:00:00+02:00", "assignment": "2023-10-09T16:03:03+02:00", "program": null, "subprogram": null, "organization": 29447, "category": 10, "type": 10, "partner_function": 4, "manager": 84449, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7818-84449-10" ] }, { "id": 8526, "title": { "de": "Metabolische Kontrolle von Altern und Krankheit", "en": "Metabolic control of aging and disease" }, "short": "MetAGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2024-10-01T02:00:00+02:00", "end_planned": "2028-09-30T02:00:00+02:00", "end_effective": "2029-09-30T02:00:00+02:00", "assignment": "2024-11-21T16:12:55+01:00", "program": 125, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 71487, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "COE14", "ethics_committee": null, "edudract_number": null, "persons": [ "8526-71487-10", "8526-116490-12", "8526-119268-12", "8526-125934-12", "8526-127474-12" ] }, { "id": 9298, "title": { "de": "BioTransform: Mapping des unbekannten menschlichen Stoffwechsels neuer biologischer Wirkstoffe in Lebensmitteln\r\n\r\n\r\n\r\n", "en": "BioTransform: Mapping the unchartered human metabolism for novel food bioactives\r\n" }, "short": "BioTransform", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2025-11-01T01:00:00+01:00", "end_planned": "2027-09-30T02:00:00+02:00", "end_effective": "2029-10-31T01:00:00+01:00", "assignment": "2025-11-05T15:18:11+01:00", "program": 209, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 2, "manager": 51266, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9298-51266-10", "9298-88711-11" ] }, { "id": 8535, "title": { "de": "Metabolische Kontrolle von Altern und Krankheit", "en": "Metabolic control of aging and disease" }, "short": "MetAGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2024-10-01T02:00:00+02:00", "end_planned": "2028-09-30T02:00:00+02:00", "end_effective": "2029-09-30T02:00:00+02:00", "assignment": "2024-11-29T14:49:59+01:00", "program": 125, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 2, "manager": 94512, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "COE14", "ethics_committee": null, "edudract_number": null, "persons": [ "8535-94512-10", "8535-129380-12" ] }, { "id": 7915, "title": { "de": "Ein atypischer Zugang zur Blutzuckerregulation - Die Rolle des atypischen Chemokinrezeptors ACKR4 in der diabetischen Stoffwechsellage", "en": "The atypical way of blood glucose regulation – investigation into the role of atypical chemokine receptor ACKR4 in metabolic homeostasis" }, "short": "ACKR4 und Hyperglykämie", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2027-04-30T02:00:00+02:00", "assignment": "2023-12-06T14:49:56+01:00", "program": null, "subprogram": null, "organization": 14084, "category": 10, "type": 10, "partner_function": 4, "manager": 86588, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7915-86124-12", "7915-86588-10", "7915-107070-12", "7915-104723-12" ] }, { "id": 7792, "title": { "de": "Cluster of Excellence: Mikrobiome steuern planetare Gesundheit", "en": "Cluster of Excellence: Microbiomes drive planetary health" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2023-10-01T02:00:00+02:00", "end_planned": "2028-09-30T02:00:00+02:00", "end_effective": "2028-09-30T02:00:00+02:00", "assignment": "2023-10-02T12:53:05+02:00", "program": 125, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 90021, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "COE 7", "ethics_committee": null, "edudract_number": null, "persons": [ "7792-65966-12", "7792-90021-10", "7792-91470-12", "7792-95832-12", "7792-99612-12", "7792-100035-12", "7792-104024-12", "7792-109121-12", "7792-100806-12", "7792-106195-12", "7792-125318-12", "7792-129735-12", "7792-127414-12" ] }, { "id": 7828, "title": { "de": "Verständnis der Rolle von großen IA-HDL bei menschlichen Erkrankungen", "en": "Understanding the role of large IA-HDL in human disease" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2023-11-01T01:00:00+01:00", "end_planned": "2024-04-30T02:00:00+02:00", "end_effective": "2025-10-31T01:00:00+01:00", "assignment": "2023-10-16T15:01:36+02:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 62749, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-93", "ethics_committee": null, "edudract_number": null, "persons": [ "7828-62749-10" ] }, { "id": 7783, "title": { "de": "Österreichisches digitales Vorhofflimmer-Screening und Interventions-Programm", "en": "Austrian Digital Atrial Fibrillation Screening and Intervention Program" }, "short": "Austrian Digital Heart Program", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2023-10-01T02:00:00+02:00", "end_planned": "2031-09-30T02:00:00+02:00", "end_effective": "2027-09-30T02:00:00+02:00", "assignment": "2023-09-26T13:05:49+02:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 1, "manager": 63032, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 19 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7783-63032-10", "7783-50168-11" ] }, { "id": 7924, "title": { "de": "Archaeen für menschliche Gesundheit", "en": "Archaea for Human Health" }, "short": "ArcHealth", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2024-02-01T01:00:00+01:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2025-07-31T02:00:00+02:00", "assignment": "2023-12-12T14:46:12+01:00", "program": 208, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 90021, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "10113895", "ethics_committee": null, "edudract_number": null, "persons": [ "7924-90021-10" ] }, { "id": 8525, "title": { "de": "Metabolische Kontrolle von Altern und Krankheit", "en": "Metabolic control of aging and disease" }, "short": "MetAGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2024-10-01T02:00:00+02:00", "end_planned": "2028-09-30T02:00:00+02:00", "end_effective": "2029-09-30T02:00:00+02:00", "assignment": "2024-11-21T16:12:41+01:00", "program": 125, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 51860, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "COE14", "ethics_committee": null, "edudract_number": null, "persons": [ "8525-70922-12", "8525-51860-10", "8525-120872-12", "8525-131699-12", "8525-124053-12", "8525-126655-12" ] } ] }