Project List

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    "results": [
        {
            "id": 2609,
            "title": {
                "de": "Hepcidin im Rahmen von Sepsis und Adipositas",
                "en": "The Role of Hepcidin in Sepsis and Obesity"
            },
            "short": "HEPCIDIN_SEPSIS_ADIPOSITAS",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2011-10-01T02:00:00+02:00",
            "end_planned": "2011-12-31T01:00:00+01:00",
            "end_effective": "2012-06-30T02:00:00+02:00",
            "assignment": "2011-10-06T15:38:08+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14049,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50778,
            "contact": 50778,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2609-50778-10"
            ]
        },
        {
            "id": 2648,
            "title": {
                "de": "Verbessert ein Lungenblähmanöver nach der Geburt die zerebrale Sauerstoffsättigung bei Frühgeborenen ?",
                "en": "Does Sustained Lung Inflation at Birth Improve Cerebral Oxygen Saturation in Preterm Infants ?"
            },
            "short": "SIPreterm",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2011-07-01T02:00:00+02:00",
            "end_planned": "2013-07-01T02:00:00+02:00",
            "end_effective": "2015-03-31T02:00:00+02:00",
            "assignment": "2011-11-24T12:12:20+01:00",
            "program": 79,
            "subprogram": null,
            "organization": 14094,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2635,
            "title": {
                "de": "Innovative Sensorik zur Quantifizierung kardialer Regelungsmechanismen bei Herzinsuffizienz (HI-Sens)",
                "en": "Innovative sensorics to quantify cardiac regulation in heart failure (HI-Sens)"
            },
            "short": "HI-Sens",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2011-11-01T01:00:00+01:00",
            "end_planned": "2012-06-30T02:00:00+02:00",
            "end_effective": "2013-03-31T01:00:00+01:00",
            "assignment": "2011-11-15T11:13:18+01:00",
            "program": null,
            "subprogram": "Human Technology Interface",
            "organization": 14083,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 51700,
            "contact": 51700,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2635-51700-10"
            ]
        },
        {
            "id": 2549,
            "title": {
                "de": "Postoperative altersentsprechende Akutschmerzerfassung bei Kindern und Jugendlichen",
                "en": "postoperative age-related assessment of acute pain in children and adolescents"
            },
            "short": "POSTOPERATIVE AGE-RELATED ACUTE PAIN",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2011-09-01T02:00:00+02:00",
            "end_planned": "2013-06-30T02:00:00+02:00",
            "end_effective": "2014-11-30T01:00:00+01:00",
            "assignment": "2011-07-29T11:15:50+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14049,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50785,
            "contact": 50785,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2549-50785-10"
            ]
        },
        {
            "id": 2871,
            "title": {
                "de": "Determinanten und neurobiologische Aspekte von Essstörungen - Gehirnaktivität als Reaktion auf Geschmacksstimuli bei Patientinnen, die an einer Essstörung leiden, im Vergleich zu deren gesunden Müttern und gesunden Kontrollpersonen",
                "en": "Determinanten und neurobiologische Aspekte bei Essstörungen"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2012-01-01T01:00:00+01:00",
            "end_planned": "2013-06-30T02:00:00+02:00",
            "end_effective": "2013-12-31T01:00:00+01:00",
            "assignment": "2012-05-24T10:54:46+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14024,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51845,
            "contact": 51845,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2871-51845-10"
            ]
        },
        {
            "id": 2616,
            "title": {
                "de": "Subtyp-spezifische, nicht kompetitive, metabotrope Glutamat Rezeptor-1 (mGluR1) Antagonisten als neuer Weg zur Therapie von neuroendokrinen Tumoren",
                "en": "Subtype-specific, non-competitive, metabotropic glutamate receptor-1 (mGluR1) antagonists as a new avenue of therapeutic intervention in neuroendocrine tumors"
            },
            "short": "GLUTAMATE RECEPTOR NEUROENDOCRINE TUMORS",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2011-07-01T02:00:00+02:00",
            "end_planned": "2014-06-30T02:00:00+02:00",
            "end_effective": "2016-06-30T02:00:00+02:00",
            "assignment": "2011-10-18T16:00:57+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14014,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2616-50379-12"
            ]
        },
        {
            "id": 2686,
            "title": {
                "de": "Disseminierende Tumorzellen in primär metastasierten Brustkrebspatientinnen mit Chirurgie des Primärtumors  ",
                "en": "Disseminating tumor cells in primary metastasized breast cancer patients undergoing surgery of primary tumor"
            },
            "short": "DISSEMINATING TUMOR CELLS_BREAST CANCER",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-07-01T02:00:00+02:00",
            "begin_effective": "2011-09-01T02:00:00+02:00",
            "end_planned": "2014-07-01T02:00:00+02:00",
            "end_effective": "2016-06-30T02:00:00+02:00",
            "assignment": "2011-12-14T13:04:08+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14085,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 59188,
            "contact": 59188,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2686-80692-12",
                "2686-97797-12",
                "2686-50539-12",
                "2686-50563-12",
                "2686-59188-10"
            ]
        },
        {
            "id": 2536,
            "title": {
                "de": "Chordome: erste Schritte in der Entwicklung neuer Therapieansätze",
                "en": "Chordomas: First steps towards a new therapy"
            },
            "short": "Chordomas: New Therapy",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2011-08-01T02:00:00+02:00",
            "end_planned": "2012-07-31T02:00:00+02:00",
            "end_effective": "2012-10-31T01:00:00+01:00",
            "assignment": "2011-07-18T14:17:06+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14052,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 53237,
            "contact": 53237,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2536-50696-12",
                "2536-61131-12",
                "2536-53237-10"
            ]
        },
        {
            "id": 2643,
            "title": {
                "de": "Einfluß der diabetischen Neuropathie auf die Stimulationsparameter der peripheren Nervenstimulation in der peripheren Nervenstimulation",
                "en": "The influence of diabetic neuropathy on the current settings during peripheral nerve stimulation for peripheral regional anesthesia"
            },
            "short": "DIABETIC NEUROPATHY PERIPHAL NERVES",
            "url": "http://www.fwf.ac.at/de/abstracts/abstract.asp?L=D&PROJ=KLI135",
            "abstract": {
                "de": "Die Prävalenz von Diabetes Mellitus (DM) wird in industrialisierten Ländern auf ungefähr 7,3% geschätzt, wobei die Inzidenz in den letzten Jahren gestiegen ist. Die Prävalenz der diabetischen Neuropathie in dieser Population wird mit bis zu 50% angegeben. Wegen der vielen Komorbiditäten von diabetischen Patienten, geht man davon aus, dass speziell diese Patientengruppe von regionalanästhesiologischen Verfahren profitieren könnte. Andererseits wird die periphere Regionalanästhesie (RA) bei Patienten mit bereits vorbestehender Neuropathie nicht empfohlen, da man eine Verschlechterung der Erkrankung durch eine Nervenverletzung beim regionalanästhesiologischen Verfahren befürchtet. Die periphere Nervenstimulation (PNS) ist das Standardverfahren in der Regionalanästhesie, bei der man den zu blockierenden Nerven mit Hilfe von Stromimpulsen, die eine motorische Reizantwort verursachen, aufsucht. Es wird davon ausgegangen, dass bei Verschwinden der motorischen Reizantwort bei 0,3 mA ein ausreichender Sicherheitsabstand vorhanden ist, um eine schädliche intraneurale Injektion des Lokalanästhetikums zu verhindern. Ob nun die diabetische Neuropathie diese Stimulationsparameter beeinflusst, ist bis heute nicht ausreichend untersucht und könnte daher ein Risiko für diese Patienten darstellen.\r\n\r\nDas beantragte Projekt untersucht die Hypothese, ob die Nerven von Patienten mit DM  weniger empfindlich auf Stromimpulse reagieren und daher die unteren Grenzwerte für die PNS in dieser Patientenpopulation deutlich höher gewählt werden müssen um eine intraneurale Injektion sicher zu verhindern. Wir möchten den Einfluss von DM auf die Erregbarkeit von peripheren Nerven anhand einer prospektiven, geblindeten, fallkontrollierten Observationsstudie  untersuchen. Dementsprechend haben wir folgende Ziele definiert.\r\n\r\nZiel 1:\tDie benötigte Stimulationsstromstärke bei Patienten mit und ohne Diabetes mellitus zu definieren.\r\nZiel 2:\tZu überprüfen ob es bei diabetischen Patienten zu einer höheren Inzidenz von neurologischen Verletzungen gibt. \r\nZiel 3:\tVon den Ergebnissen geleitete Empfehlungen für die Durchführung von regionalanästhesiologischen Verfahren bei diabetischen Patienten zu generieren. \r\n\r\nDie Ergebnisse dieser Studie werden das Verständnis von der Nadel-Strom-Nerven-Beziehung bei peripherer Nervenstimulation deutlich verbessern und dadurch einen immensen Einfluss auf die Patientensicherheit während regionalanästhesiologischer Verfahren haben, besonders in der Patientenpopulation mit bereits vorbestehender Neuropathie. \r\n",
                "en": "The prevalence of diabetes mellitus (DM) in industrialized countries is estimated to be about 7.3% and its incidence has been growing in recent years. The prevalence of diabetic neuropathy in the diabetic patient population is up to 50%. When limb surgery is necessary, it is reasonable to assume that diabetic patients will benefit from a regional anesthetic because of the severe comorbidities associated with DM. On the other hand, the use of regional anesthesia (RA) has generally not been recommended in patients with preexisting neuropathies mainly because of medical liability issues, as worsening neuropathy could be attributed to nerve damage caused by the regional anesthetic. The current state of the art of peripheral regional anesthesia for the identification of correct placement of an injection needle suitably close to the target nerve is to elicit a motor response by current injection through the needle. Constant reduction of the current as the nerve is approached ensures close proximity so that an effective nerve block is obtained when the local anesthetic is delivered through the needle, and absence of a motor response at 0.3 mA is generally accepted as a safety marker to avoid harmful intraneural injection. An important deficit in our understanding is whether diabetic neuropathy influences the stimulation parameters for peripheral nerve stimulation (PNS), possibly decreasing safety.\r\n\r\nThe currently proposed research is guided by the hypothesis that nerves in patients with DM are resistant to stimulation and, as a consequence, the current thresholds for PNS have to be set much higher to prevent injections from occurring within the epineurium. We will examine this the effect of DM on nerve excitability in a blinded, prospective, observational case control trial. Accordingly, we have defined following aims:\r\n\r\nAim 1: \tTo characterize the required stimulation current in patients with and without diabetes mellitus. \r\nAim 2: \tFollow-up to examine if the rate of adverse neurologic events is higher in diabetic patients.\r\nAim 3: \tGuided by the results, formulate recommendations for the performance of regional anesthesia in patients with a history of DM.\r\n\r\nThese experiments will provide better understanding of the needle-current-nerve relationship during peripheral nerve stimulation. Findings from this proposed study will have a major impact on patient safety, especially in the subgroup with preexisting neuropathy, undergoing regional anesthesia\r\n"
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2012-01-01T01:00:00+01:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-09-30T02:00:00+02:00",
            "assignment": "2011-11-18T14:50:50+01:00",
            "program": 108,
            "subprogram": "KLIF",
            "organization": 14069,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "KLI135",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2643-50869-11",
                "2643-67711-11",
                "2643-75117-12",
                "2643-50731-12"
            ]
        },
        {
            "id": 3285,
            "title": {
                "de": "Endoskopische, bildverarbeitungsgestützte Diagnostik frühmagnialer Veräderungen bei Barretts-Ösophagus",
                "en": "Endoskopische, bildverarbeitungsgestützte Diagnostik frühmagnialer Veräderungen bei Barretts-Ösophagus"
            },
            "short": "EBIDAVROS",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2011-08-01T02:00:00+02:00",
            "end_planned": "2012-08-31T02:00:00+02:00",
            "end_effective": "2013-07-30T02:00:00+02:00",
            "assignment": "2013-05-23T11:43:59+02:00",
            "program": null,
            "subprogram": "HTI",
            "organization": 14081,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 51539,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3285-51539-10"
            ]
        },
        {
            "id": 2556,
            "title": {
                "de": "Die Rolle von Lipasen bei Patienten mit Pankreaskarzinom",
                "en": "The role of lipases in patients with pancreatic cancer"
            },
            "short": "LIPASES PATIENTS PANCREATIC CANCER",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2011-09-01T02:00:00+02:00",
            "end_planned": "2013-07-31T02:00:00+02:00",
            "end_effective": "2014-12-31T01:00:00+01:00",
            "assignment": "2011-08-22T12:09:00+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14020,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2608,
            "title": {
                "de": "Biphasischer PNA FISH Test zur antizipativen Diagnose von Zentralvenenkatheter-assoziierten Bakteriämien/Fungämien Projektnummer:832079",
                "en": "Anticipative Diagnosis of Catheter-related Bloodstream Infections with biphasic PNA-FISH"
            },
            "short": "CRBSI screening",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2011-09-01T02:00:00+02:00",
            "end_planned": "2014-07-31T02:00:00+02:00",
            "end_effective": "2015-09-30T02:00:00+02:00",
            "assignment": "2011-10-06T12:20:10+02:00",
            "program": 60,
            "subprogram": null,
            "organization": 14087,
            "category": 10,
            "type": 10,
            "partner_function": 3,
            "manager": 51976,
            "contact": 51976,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                416
            ],
            "funder_projectcode": "832079 ",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2608-51976-10"
            ]
        },
        {
            "id": 2526,
            "title": {
                "de": "Rezeptoren und Metabolite von Prostaglandinen im Morbus Crohn und der ulzerösen Kolitis",
                "en": "DP receptors and their prostaglandin metabolite ligands: a good or bad match for human IBD?"
            },
            "short": "DP receptors in IBD",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2011-08-01T02:00:00+02:00",
            "end_planned": "2013-07-31T02:00:00+02:00",
            "end_effective": "2013-07-31T02:00:00+02:00",
            "assignment": "2011-07-12T16:34:21+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14022,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 56687,
            "contact": 56687,
            "status": 2,
            "research": 3,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2526-56687-10"
            ]
        },
        {
            "id": 2537,
            "title": {
                "de": "Klinische Relevanz von Keimbahnpolymorphismen in Wnt/Notch/Hedgehog für Prognose bei Kolonkarzinomen",
                "en": "Clinical impact of germline polymorphisms in Wnt/Notch/Hedgehog for colon cancer outcome"
            },
            "short": "GERMLINE POLYMORPH COLON CANCER",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2011-11-01T01:00:00+01:00",
            "end_planned": "2012-07-31T02:00:00+02:00",
            "end_effective": "2012-10-31T01:00:00+01:00",
            "assignment": "2011-07-19T11:01:17+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14085,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 58814,
            "contact": 58814,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2537-58814-10"
            ]
        },
        {
            "id": 2720,
            "title": {
                "de": "Ko-Kultursystem für die frühe Plazentation mit unterschiedlichen Sauerstoffkonzentrationen",
                "en": "Co-Culture System for early placentation with different oxygen-concentrations"
            },
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