GET
json api

Project List

List projects.

Fields

id (integer)

Primary key.

Expansions

To activate relation expansion add the desired fields as a comma separated list to the expand query parameter like this:

?expand=<field>,<field>,<field>,...

The following relational fields can be expanded:

  • organization
  • category
  • type
  • partner_function
  • manager
  • contact
  • status
  • grant
  • research
  • event
  • study
  • language
  • program
  • funders

Filters

To filter for exact value matches:

?<fieldname>=<value>

Possible exact filters:

  • organization
  • category
  • manager
  • contact
  • status
  • grant
  • research
  • study
  • language
  • funders
  • program

For advanced filtering use lookups:

?<fieldname>__<lookup>=<value>

All fields with advanced lookups can also be used for exact value matches as described above.

Possible advanced lookups:

  • begin_planned: gt, gte, lt, lte
  • begin_effective: gt, gte, lt, lte
  • end_planned: gt, gte, lt, lte
  • end_effective: gt, gte, lt, lte
GET /v1/research/project/?format=api&offset=400&ordering=end_planned
HTTP 200 OK
  Allow: GET, HEAD, OPTIONS
  Content-Type: application/json
  Vary: Accept
  
  {
    "count": 2261,
    "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=420&ordering=end_planned",
    "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=380&ordering=end_planned",
    "results": [
        {
            "id": 2920,
            "title": {
                "de": "Modellierung der intra-abdominellen Hypertonie",
                "en": "Modeling Intra-abdominal Hypertension"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-07-01T02:00:00+02:00",
            "begin_effective": "2012-07-01T02:00:00+02:00",
            "end_planned": "2012-12-31T01:00:00+01:00",
            "end_effective": "2013-12-31T01:00:00+01:00",
            "assignment": "2012-07-23T10:14:08+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14010,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2395,
            "title": {
                "de": "Mechanische Änderungen von Musculus Triceps Surae im Laufe des  Skelettwachstums - funktionelle Beurteilung von Kontrakturen bei Kindern mit spastischer diplegischer Zerebralparese",
                "en": "Mechanical changes of triceps surae muscle with skeletal growth - functional evaluation of contractures in children with spastic diplegic cerebral palsy"
            },
            "short": "MECHANICAL CHANGES SKELETAL GROWTH",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-01-01T01:00:00+01:00",
            "begin_effective": "2011-01-01T01:00:00+01:00",
            "end_planned": "2012-12-31T01:00:00+01:00",
            "end_effective": "2013-02-28T01:00:00+01:00",
            "assignment": "2011-02-04T12:14:35+01:00",
            "program": null,
            "subprogram": "Österreichische Akademie der Wissenschaften -\r\nAustrian Programme for Advanced Research and Technology ",
            "organization": 14049,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 65038,
            "contact": 65038,
            "status": 2,
            "research": 5,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                15
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2395-65038-10"
            ]
        },
        {
            "id": 2103,
            "title": {
                "de": "Fatty liver: Inhibition of Progression (Role of hepatic triglyceride lipases in the progression of NASH)",
                "en": "Fatty liver: Inhibition of Progression (Role of hepatic triglyceride lipases in the progression of NASH)"
            },
            "short": "FLIP",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-01-01T01:00:00+01:00",
            "begin_effective": "2010-01-01T01:00:00+01:00",
            "end_planned": "2012-12-31T01:00:00+01:00",
            "end_effective": "2012-12-31T01:00:00+01:00",
            "assignment": "2010-02-10T16:24:47+01:00",
            "program": 24,
            "subprogram": "HEALTH-2009-2.4.5-1",
            "organization": 14081,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                10
            ],
            "funder_projectcode": "241762",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2912,
            "title": {
                "de": "Gehirnprotektion für sehr kleine Frühgeborene",
                "en": "SafeBoosC - Safeguarding the brain of our smallest children"
            },
            "short": "SafeBoosC",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-02-01T01:00:00+01:00",
            "begin_effective": "2012-07-05T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2016-09-21T02:00:00+02:00",
            "assignment": "2012-07-10T13:21:26+02:00",
            "program": null,
            "subprogram": "Danish Council for Strategic Research ",
            "organization": 14094,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 50907,
            "contact": 50907,
            "status": 2,
            "research": 5,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1152
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2912-50907-10"
            ]
        },
        {
            "id": 2850,
            "title": {
                "de": "Hochdruckerkrankung und Proteinurie in der Schwangerschaft (Präeklampsie). Methoden der nichtlinearen Dynamik zur Analyse von hämodynamischen Kenngrößen während der Schwangerschaft.",
                "en": "Hypertension and proteinuria during pregnancy (preeclampsia)"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-06-01T02:00:00+02:00",
            "begin_effective": "2012-06-01T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-10-31T01:00:00+01:00",
            "assignment": "2012-05-10T14:37:45+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14010,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 64295,
            "contact": 64295,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2850-64295-10"
            ]
        },
        {
            "id": 2804,
            "title": {
                "de": "Untersuchung des unterschiedlichen Proliferationsverhaltens von Zellen in der Tumorzellinie MUG-Chor1",
                "en": "Investigation of different proliferation behavior of cells in the tumor cell MUG Chor1"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-02-01T01:00:00+01:00",
            "begin_effective": "2012-02-01T01:00:00+01:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-01-31T01:00:00+01:00",
            "assignment": "2012-02-22T15:38:11+01:00",
            "program": null,
            "subprogram": null,
            "organization": 17218,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50826,
            "contact": 50826,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2804-50826-10"
            ]
        },
        {
            "id": 3192,
            "title": {
                "de": "Struktur der Apolipoproteine B100 und VLDL-II",
                "en": "Structure of Apolipopoteins B100 and VLDL-II"
            },
            "short": "ApoB100",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2008-02-01T01:00:00+01:00",
            "begin_effective": "2008-02-01T01:00:00+01:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-01-31T01:00:00+01:00",
            "assignment": "2013-03-01T09:09:01+01:00",
            "program": 72,
            "subprogram": null,
            "organization": 14011,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 83066,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "P20455",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "3192-83066-10"
            ]
        },
        {
            "id": 2643,
            "title": {
                "de": "Einfluß der diabetischen Neuropathie auf die Stimulationsparameter der peripheren Nervenstimulation in der peripheren Nervenstimulation",
                "en": "The influence of diabetic neuropathy on the current settings during peripheral nerve stimulation for peripheral regional anesthesia"
            },
            "short": "DIABETIC NEUROPATHY PERIPHAL NERVES",
            "url": "http://www.fwf.ac.at/de/abstracts/abstract.asp?L=D&PROJ=KLI135",
            "abstract": {
                "de": "Die Prävalenz von Diabetes Mellitus (DM) wird in industrialisierten Ländern auf ungefähr 7,3% geschätzt, wobei die Inzidenz in den letzten Jahren gestiegen ist. Die Prävalenz der diabetischen Neuropathie in dieser Population wird mit bis zu 50% angegeben. Wegen der vielen Komorbiditäten von diabetischen Patienten, geht man davon aus, dass speziell diese Patientengruppe von regionalanästhesiologischen Verfahren profitieren könnte. Andererseits wird die periphere Regionalanästhesie (RA) bei Patienten mit bereits vorbestehender Neuropathie nicht empfohlen, da man eine Verschlechterung der Erkrankung durch eine Nervenverletzung beim regionalanästhesiologischen Verfahren befürchtet. Die periphere Nervenstimulation (PNS) ist das Standardverfahren in der Regionalanästhesie, bei der man den zu blockierenden Nerven mit Hilfe von Stromimpulsen, die eine motorische Reizantwort verursachen, aufsucht. Es wird davon ausgegangen, dass bei Verschwinden der motorischen Reizantwort bei 0,3 mA ein ausreichender Sicherheitsabstand vorhanden ist, um eine schädliche intraneurale Injektion des Lokalanästhetikums zu verhindern. Ob nun die diabetische Neuropathie diese Stimulationsparameter beeinflusst, ist bis heute nicht ausreichend untersucht und könnte daher ein Risiko für diese Patienten darstellen.\r\n\r\nDas beantragte Projekt untersucht die Hypothese, ob die Nerven von Patienten mit DM  weniger empfindlich auf Stromimpulse reagieren und daher die unteren Grenzwerte für die PNS in dieser Patientenpopulation deutlich höher gewählt werden müssen um eine intraneurale Injektion sicher zu verhindern. Wir möchten den Einfluss von DM auf die Erregbarkeit von peripheren Nerven anhand einer prospektiven, geblindeten, fallkontrollierten Observationsstudie  untersuchen. Dementsprechend haben wir folgende Ziele definiert.\r\n\r\nZiel 1:\tDie benötigte Stimulationsstromstärke bei Patienten mit und ohne Diabetes mellitus zu definieren.\r\nZiel 2:\tZu überprüfen ob es bei diabetischen Patienten zu einer höheren Inzidenz von neurologischen Verletzungen gibt. \r\nZiel 3:\tVon den Ergebnissen geleitete Empfehlungen für die Durchführung von regionalanästhesiologischen Verfahren bei diabetischen Patienten zu generieren. \r\n\r\nDie Ergebnisse dieser Studie werden das Verständnis von der Nadel-Strom-Nerven-Beziehung bei peripherer Nervenstimulation deutlich verbessern und dadurch einen immensen Einfluss auf die Patientensicherheit während regionalanästhesiologischer Verfahren haben, besonders in der Patientenpopulation mit bereits vorbestehender Neuropathie. \r\n",
                "en": "The prevalence of diabetes mellitus (DM) in industrialized countries is estimated to be about 7.3% and its incidence has been growing in recent years. The prevalence of diabetic neuropathy in the diabetic patient population is up to 50%. When limb surgery is necessary, it is reasonable to assume that diabetic patients will benefit from a regional anesthetic because of the severe comorbidities associated with DM. On the other hand, the use of regional anesthesia (RA) has generally not been recommended in patients with preexisting neuropathies mainly because of medical liability issues, as worsening neuropathy could be attributed to nerve damage caused by the regional anesthetic. The current state of the art of peripheral regional anesthesia for the identification of correct placement of an injection needle suitably close to the target nerve is to elicit a motor response by current injection through the needle. Constant reduction of the current as the nerve is approached ensures close proximity so that an effective nerve block is obtained when the local anesthetic is delivered through the needle, and absence of a motor response at 0.3 mA is generally accepted as a safety marker to avoid harmful intraneural injection. An important deficit in our understanding is whether diabetic neuropathy influences the stimulation parameters for peripheral nerve stimulation (PNS), possibly decreasing safety.\r\n\r\nThe currently proposed research is guided by the hypothesis that nerves in patients with DM are resistant to stimulation and, as a consequence, the current thresholds for PNS have to be set much higher to prevent injections from occurring within the epineurium. We will examine this the effect of DM on nerve excitability in a blinded, prospective, observational case control trial. Accordingly, we have defined following aims:\r\n\r\nAim 1: \tTo characterize the required stimulation current in patients with and without diabetes mellitus. \r\nAim 2: \tFollow-up to examine if the rate of adverse neurologic events is higher in diabetic patients.\r\nAim 3: \tGuided by the results, formulate recommendations for the performance of regional anesthesia in patients with a history of DM.\r\n\r\nThese experiments will provide better understanding of the needle-current-nerve relationship during peripheral nerve stimulation. Findings from this proposed study will have a major impact on patient safety, especially in the subgroup with preexisting neuropathy, undergoing regional anesthesia\r\n"
            },
            "begin_planned": "2011-08-01T02:00:00+02:00",
            "begin_effective": "2012-01-01T01:00:00+01:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-09-30T02:00:00+02:00",
            "assignment": "2011-11-18T14:50:50+01:00",
            "program": 108,
            "subprogram": "KLIF",
            "organization": 14069,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "KLI135",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2643-50869-11",
                "2643-67711-11",
                "2643-75117-12",
                "2643-50731-12"
            ]
        },
        {
            "id": 2722,
            "title": {
                "de": "BABICA Blutgasanalyse und Puffertherapie beim Herz-Kreislaufstillstand",
                "en": "BABICA Blood gas analysis and buffer therapy in cardac arrest"
            },
            "short": "BABICA",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-04-01T02:00:00+02:00",
            "begin_effective": "2011-04-01T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-01-31T01:00:00+01:00",
            "assignment": "2012-01-12T09:32:44+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14069,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51986,
            "contact": 51986,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1330
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2722-51986-10"
            ]
        },
        {
            "id": 2390,
            "title": {
                "de": "Suche genetischer Faktoren in Neurotrophinen beim primären Offenwinkelglaukom",
                "en": "Candidate Gene Analysis in Neurotrophins in Primary Open Angle Glaucoma using Haplotype Tagging Single Nucleotide Polymorphisms"
            },
            "short": "CANDIDATE GENE ANALYSIS_GLAUCOMA",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-02-01T01:00:00+01:00",
            "begin_effective": "2011-04-01T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2012-03-31T02:00:00+02:00",
            "assignment": "2011-02-04T09:28:08+01:00",
            "program": 79,
            "subprogram": null,
            "organization": 14043,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2849,
            "title": {
                "de": "\"Fettstoffwechselstörungen und anthropometrische Besonderheiten bei PatientInnen mit bipolarer affektiver Störung\"",
                "en": "\"Disturbed lipid metabolism and anthropometric variants in bipolar disorder\""
            },
            "short": "FATBIP",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-04-01T02:00:00+02:00",
            "begin_effective": "2012-04-01T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-04-30T02:00:00+02:00",
            "assignment": "2012-05-10T13:10:38+02:00",
            "program": null,
            "subprogram": null,
            "organization": 29444,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                457
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2723,
            "title": {
                "de": "Blutgasanalyse und Puffertherapie beim Herzkreislaufstillstand",
                "en": "Blood Gas Analysis and Buffer Therapy in Cardiac Arrest"
            },
            "short": "BABICA",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-04-01T02:00:00+02:00",
            "begin_effective": "2011-04-01T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-01-31T01:00:00+01:00",
            "assignment": "2012-01-12T09:33:12+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14069,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51986,
            "contact": 51986,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2723-51986-10"
            ]
        },
        {
            "id": 2903,
            "title": {
                "de": "Einfluss von Stress auf die Arterielle Gefäßsteifigkeit bei Kindern und Jugendlichen",
                "en": "Influence of Stress on Arterial Stiffness in Children"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-04-11T02:00:00+02:00",
            "begin_effective": "2012-06-25T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-03-30T01:00:00+01:00",
            "assignment": "2012-06-26T11:45:49+02:00",
            "program": null,
            "subprogram": null,
            "organization": 29447,
            "category": 10,
            "type": 10,
            "partner_function": 1,
            "manager": 60388,
            "contact": 60388,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2903-60388-10"
            ]
        },
        {
            "id": 2934,
            "title": {
                "de": "Betreibung eines Ko-Kultursystems für die frühe Plazentation mit unterschiedlichen Sauerstoffkonzentrationen",
                "en": "Operation of a Co-Culture System for early placentation with different oxygen-concentrations "
            },
            "short": "Betreibung Ko-Kultur",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-07-01T02:00:00+02:00",
            "begin_effective": "2012-08-01T02:00:00+02:00",
            "end_planned": "2013-01-31T01:00:00+01:00",
            "end_effective": "2013-05-31T02:00:00+02:00",
            "assignment": "2012-07-26T11:00:53+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14017,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 58943,
            "contact": 58943,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2934-58943-10"
            ]
        },
        {
            "id": 2306,
            "title": {
                "de": "Zellbasierte nichtinvasive Pränataldiagnostik",
                "en": "Cell-based non-invasive prenatal diagnosis"
            },
            "short": "ZELLBAS NICHTINV PRAENATALDIAG",
            "url": null,
            "abstract": {
                "de": "Genetische Pränataldiagostik erfordert die Gewinnung von Zellen des Kindes. Dies erfolgt durch invasive Methoden wie Amniozentese oder Chorionzottenbiopsie. Das Risiko, daß es durch diese Eingriffe zu einem Abort kommt, ist nicht vernachlässigbar und liegt bei 0,5 – 1%.  Aus diesem Grund ist genetische Pränataldiagnostik auf Schwangerschaften mit einem erhöhten Risiko einer genetischen Krankheit des Fetus beschränkt, wie z. B. einem Alter der Schwangeren von über 35 Jahren. Tatsächlich wird aber die Mehrzahl von Kindern mit genetischen Krankheiten nach Schwangerschaften geboren, die nicht primär als mit erhöhtem Risiko behaftet eingestuft werden können und bei denen das Risiko einer invasive Diagnostik in keinem vertretbaren Verhältnis zum Risiko durch den Eingriff steht.\r\nAusgehend von einer von uns entwickelten Methode zur geschlechtsunabhängigen Analyse der fötalen Identität von Zellen wollen wir in dem vorgeschlagenen Projekt ein Verfahren etablieren, das auf der Basis der Analyse von Einzelzellen eine nicht-invasive pränatale Diagnostik numerischer Chromosomenaberrationen und monogenetisch bedingter Krankheiten ermöglicht. Wir vergleichen die Effizienz etablierter Protokolle zur Anreicherung fetaler Zellen aus dem peripheren Blut schwangerer Frauen. Weiters etablieren wir die Amplifikation des gesamten Genoms von Einzelzellen, kombinieren die Analyse der fetalen Identität mittels array comparative genomic hybridization zur Analyse von Trisomien und analysieren als Beispiel der prinzipiellen Machbarkeit Mutationen des CFTR Gens.\r\nAuf Basis dieser Arbeiten wollen wir unter Nutzung von Ressourcen der Medizinischen Universität Graz im Sinn einer kommerziellen Anwendung ein überregionales Zentrum zur zellbasierten nichtinvasiven Pränataldiagnostik etablieren.\r\n",
                "en": "Genetic prenatal diagnosis is dependent on procurement of fetal cells. This is done my invasive methods such as amniocentesis and chorionic villous sampling. These methods are associated to a risk of 0.5 – 1% of subsequent abortus. For this reason genetic prenatal diagnosis is restricted to pregnancies with are associated with an increased risk of renetik disease of the fetus, such as age of the pregnant women higher than 35 years. In fact the majority of children with genetic diseases is born at the end of pregnancies which have not abeen associated with an increased risk, where the risk of invasive procedures cannot be  justified.\r\nBased on a method which we developed previously for sex-independent analysis of the fetal identity of cells in a fetal microchimeric setting, we plan to establish a technique allowing for non-invasive prenatal diagnosis of both numeric chromosomal aberrations and monogenetic hereditary diseases, using analysis of single cells. We will compare the efficiency of established protocols for enrichment of fetal cells from the peripheral blood of pregnant women. Furthermore, we will establish whole genome amplification of single cells and combine the analysis of fetal identity with analysis of trisomy by means of array comparative genomic hybridization. As a proof of principle for feasibility of analysis of monogenic hereditary diseases using the preamplified genome of single cells we will analyze mutations of the CFTR gene.\r\nThe results of this work will be commercially exploited as we plan to establish an supra-regional center for cell-based non-invasive prenatal diagnosis by using the facilities of the Medical University of Graz.\r\n"
            },
            "begin_planned": "2010-03-01T01:00:00+01:00",
            "begin_effective": "2010-12-01T01:00:00+01:00",
            "end_planned": "2013-02-28T01:00:00+01:00",
            "end_effective": "2014-12-31T01:00:00+01:00",
            "assignment": "2010-09-17T13:41:38+02:00",
            "program": 71,
            "subprogram": null,
            "organization": 14017,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "TRP17 ",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2306-54171-12"
            ]
        },
        {
            "id": 2787,
            "title": {
                "de": "Entwicklung eines EORTC Fragebogens zur Erfassung der Sexualität von onkologischen PatientInnen",
                "en": "Development of an EORTC questionnaire for assessing sexual health in cancer patients"
            },
            "short": "EORTC Sexual Health Questionnaire",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-03-01T01:00:00+01:00",
            "begin_effective": "2012-03-01T01:00:00+01:00",
            "end_planned": "2013-02-28T01:00:00+01:00",
            "end_effective": "2013-02-28T01:00:00+01:00",
            "assignment": "2012-02-14T15:16:23+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14038,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                442
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2633,
            "title": {
                "de": "Interface Mundraum: Analyse und in vitro Simulation oraler Bakteriengemeinschaften auf natürlichen und künstlichen Materialien",
                "en": "Interface oral cavity: analyses and in vitro simulation of oral bacterial communities on natural and artificial surfaces"
            },
            "short": "OraSim",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-11-01T01:00:00+01:00",
            "begin_effective": "2011-11-01T01:00:00+01:00",
            "end_planned": "2013-02-28T01:00:00+01:00",
            "end_effective": "2013-06-30T02:00:00+02:00",
            "assignment": "2011-11-09T15:28:14+01:00",
            "program": null,
            "subprogram": "Human Technology Interface",
            "organization": 14109,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50051,
            "contact": 50051,
            "status": 2,
            "research": 3,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2633-50051-10"
            ]
        },
        {
            "id": 2682,
            "title": {
                "de": "Nachhaltige Grazer biomedizintechnische TCM-Forschung zur Prävention chronischer Erkrankungen",
                "en": "Sustainable biomedical engineering TCM-research in Graz for prevention of chronic diseases"
            },
            "short": "Grazer Biomed TCM",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-09-01T02:00:00+02:00",
            "begin_effective": "2011-12-01T01:00:00+01:00",
            "end_planned": "2013-02-28T01:00:00+01:00",
            "end_effective": "2013-06-30T02:00:00+02:00",
            "assignment": "2011-12-13T11:32:16+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14044,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                457
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2979,
            "title": {
                "de": "Eosinophile und die antivirale Immunabwehr gegen H1N1",
                "en": "Eosinophils promote host defense against H1N1 influenza"
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-09-01T02:00:00+02:00",
            "begin_effective": "2012-10-01T02:00:00+02:00",
            "end_planned": "2013-02-28T01:00:00+01:00",
            "end_effective": "2013-03-31T01:00:00+01:00",
            "assignment": "2012-09-20T11:28:45+02:00",
            "program": 69,
            "subprogram": null,
            "organization": 14022,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50791,
            "contact": 50791,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                9
            ],
            "funder_projectcode": "J3235",
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2979-50791-10"
            ]
        },
        {
            "id": 2805,
            "title": {
                "de": "Intracellular Calcium Store Alterations in Dorsal Root Ganglion Neurons from Non-hyperalgesic Rats after Peripheral Nerve Injury.",
                "en": "Veränderungen der intrazellulären Kalzium-Speicher in Spinalganglienneuronen von nicht hyperalgetischen Ratten nach Nervenläsion."
            },
            "short": null,
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2012-02-01T01:00:00+01:00",
            "begin_effective": "2012-02-01T01:00:00+01:00",
            "end_planned": "2013-02-28T01:00:00+01:00",
            "end_effective": "2015-03-31T02:00:00+02:00",
            "assignment": "2012-02-23T10:28:31+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14069,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50869,
            "contact": 50869,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                1308
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2805-50869-10",
                "2805-71082-12"
            ]
        }
    ]
}