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GET /v1/research/project/?format=api&offset=320&ordering=-begin_planned
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=340&ordering=-begin_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=300&ordering=-begin_planned", "results": [ { "id": 7739, "title": { "de": "Evaluierung innovativer molekularer Analyseverfahren und -ansätze zur Überwachung von Antibiotikaresistenzen im Abwasser", "en": "Evaluation of innovative molecular analytical methods and approaches for monitoring antibiotic resistance in wastewater" }, "short": "ARISE", "url": null, "abstract": { "de": "Universelle DNA/RNA Diagnostik. Es soll die technische Realisier- und Leistungsfähigkeit einer neuen universell einsetzbaren molekularbiologischen Nachweisstrategie für die robuste und sensitive DNA/RNA-Diagnostik biologischer („emerging“) Gefährdungen aller Art für das Abwassermonitoring von Morgen demonstriert werden. Dies wird am Beispiel bakterieller Antibiotikaresistenzen (ARB) – auf Basis einer zukunftsweisenden neuartigen molekularbiologischen Toolbox – durchgeführt. Einerseits stellt die ARB-Problematik eine der größten zukünftigen medizinischen globalen Herausforderungen dar (= größte Relevanz), andererseits sind bereits neue leistungsfähige methodische Teillösungen vorhanden, die in kurzer Zeit zur vorgeschlagenen Toolbox kombiniert werden können (= schnelle Umsetzbarkeit). Da diese auf einer Analyse genetischer Sequenzen basiert, ist eine schnelle Ausweitung auf andere biologische Gefährdungen möglich (nach Anpassung der Sampling- und Probenaufarbeitung).\r\nWasserkreislauf-basierter Ansatz. Die vorgeschlagene Nachweisstrategie soll darüber hinaus erstmals simultane Rückschlüsse auf, i) Verbreitung und Infektionsprävalenz des überwachten Bevölkerungskollektivs im Einzugsgebiet der Abwasserentsorgung (d.h. eigentliche Abwasser-epidemiologie - „Upstream-Verfahren“), als auch, ii) die Gefährdung für Mensch- und Natur (z.B. Nutzung als Badewässer, Trinkwasser oder Fischereigewässer) im Zuge der Ausbreitung über den nachgeschalteten Vorfluter und Wasserkreislauf, ermöglichen (d.h. nutzungsbasierte Gefährdungs- und Risikoanalyse der beeinflussten Wasserressource). \r\nOne-Health Monitoring & Management. Da ARB – wie auch viele andere biologische Gefährdungen – humanen und tierischen Ursprung haben und beidseitige Relevanz besitzen können, wird das vorgeschlagene Tool auf alle Arten fäkaler Abwässer entwickelt und ermöglicht eine Zuordnung und Differenzierung (molekulares fäkales Source-Tracking). Dadurch wird eine universell anwendbare Toolbox im Sinne eines One-Health Ansatzes ermöglicht.\r\nBis Dato vorhandene Limitierungen. Verfügbare molekularbiologische Anwendungen sind i.d.R. i) sensitiv und spezifisch, aber auf wenige Targets beschränkt (z.B. qPCR, RT-qPCR), oder, ii) universell, auf viele Targets einsetzbar, aber wenig sensitiv (z.B. gängige Hochdurchsatz-Sequenzierungsmethoden). Zum anderen erfolgt der Nachweis biologischer Gefährdungen im Abwasser bislang weitgehend ohne Berücksichtigung der Quantität und Qualität der fäkalen Belastungssituation (d.h. Ausmaß, Charakteristik und Herkunft der fäkalen mikrobiologischen Beeinflussung).\r\n", "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2023-08-29T16:37:42+02:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 58733, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999905348", "ethics_committee": null, "edudract_number": null, "persons": [ "7739-54018-11", "7739-58733-10", "7739-103077-12" ] }, { "id": 8133, "title": { "de": "Alterssuizid in Österreich: Eine Niedrig- und Hochrisikopopulationsstudie basierend auf verknüpften personenbezogenen Registerdaten", "en": "Suicide among older adults in Austria: A low- and high-risk population study based on linked individual-level register data" }, "short": "SAOAA", "url": "https://www.oeaw.ac.at/foerderungen/data-research-austria", "abstract": { "de": "Der Suizid eines Menschen ist eine Tragödie auf individueller Ebene und gleichzeitig ein Problem der öffentlichen Gesundheitsfürsorge auf gesellschaftlicher Ebene. Wenig bekannt ist dabei, dass die Suizidraten sowohl in Österreich als auch allen anderen europäischen Ländern stark mit dem Alter ansteigen. Die allerhöchsten Suizidraten finden sich bei hochaltrigen Männern. Österreich hat gegenwärtig eine der höchsten Suizidraten bei Hochaltrigen in ganz Europa und es wird erwartet, dass die absolute Zahl der Suizide bei älteren Menschen in den nächsten Dekaden aufgrund der fortschreitenden Überalterung der Bevölkerung, insbesondere durch das Älterwerden der Babyboomer-Generation, steigen wird. Die zentrale Forschungsfrage dieses Projekts ist daher, welche Risikofaktoren Suizide bei älteren Menschen in Österreich vorhersagen können, was in weiterer Folge dazu beitragen soll, Präventionsmaßnahmen zu verbessern. Vor dem Hintergrund erstmalig zugänglicher und auf individueller Ebene verknüpfbarer Registerdaten in Österreich durch das Austria Micro Data Center (AMDC) soll im Rahmen dieses Projekts untersucht werden, welche älteren Personengruppen ein erhöhtes Risiko für Suizid haben. Konkret planen wir Risikofaktoren in zwei Bevölkerungsgruppen zu untersuchen: (1) die gesamte ältere Allgemeinbevölkerung (Niedrigrisiko-Ansatz) und (2) ältere gerontopsychiatrische Patient*innen (Hochrisiko-Ansatz). Potentielle Risikofaktoren werden demographische und sozioökonomische Faktoren, körperliche und psychische Erkrankungen, Pflegebedürftigkeit und soziale Isolation umfassen. Dabei werden diese Risikofaktoren nicht nur isoliert voneinander betrachtet, sondern auch deren multiplikativer Effekt, d.h. wenn beispielsweise der Verlust eines Partners mit einer neuen Krebsdiagnose zusammenfällt, untersucht. Mit diesem Forschungsprojekt wollen wir den Alterssuizid in Österreich besser verstehen und damit eine bessere Grundlage für Präventionsmaßnahmen schaffen, und nicht zuletzt die Lebensumstände jener älteren Personen besser zu beleuchten, die keinen anderen Ausweg sehen, als sich selbst (oft mit Gewalt) das Leben zu nehmen. ", "en": "Suicide is a tragedy at the individual level and a serious public health problem at the societal level. Although often overlooked, suicide rates in both Austria and other European countries increase rapidly with age, so that the highest suicide rates tend to show among the oldest old, and here, specifically among men. Austria has one of the highest suicide rates among the oldest old within the EU-27 countries. The high number of suicide deaths among older adults in Austria is not only a present-day concern, but also worrying against the background of population ageing, specifically the ageing of the large baby boomer generation, as this will likely lead to an increase in the absolute number of suicides among older adults in the decades ahead. The main research question of this project therefore is what risk factors can predict old age suicides in Austria, which can subsequently inform suicide prevention efforts. Against the background of newly available individual-level register data linkage in Austria within the Austrian Micro Data Center (AMDC), the aim of this project is to provide new and hitherto unavailable evidence on who among the older population is at an elevated risk of suicide death. Specifically, we seek to identify risk factors in two populations: (1) the whole general older population (low-risk setting) and (2) older psychiatric inpatients (high-risk setting). Risk factors will include demographic and socioeconomic factors, physical and mental health problems, disability and social disconnectedness. We will not only look at these factors in isolation, but also assess whether there are multiplicative effects for suicide risk, that is, when multiple risk factors co-occur at the same time, e.g. when the loss of spouse coincides with a cancer diagnosis. With this research project, we aim to better understand old age suicide in Austria, to inform suicide prevention efforts, and to illuminate the life circumstances of those older adults who see no other way but to (often violently) end their own lives." }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-07-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2024-04-10T11:05:11+02:00", "program": 245, "subprogram": null, "organization": 14024, "category": 10, "type": 10, "partner_function": 1, "manager": 89152, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 15 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8133-89152-10", "8133-119651-12", "8133-128434-12" ] }, { "id": 8065, "title": { "de": "Digitalisierung von innovativen Pflegeprozessen \r\nzur Entlastung und Befähigung von Pflegekräften", "en": "Digitalisation of Innovative Care Processes \r\nto Unburden and Empower Nurses\r\n" }, "short": "N!CA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2027-12-31T01:00:00+01:00", "end_effective": "2028-02-29T01:00:00+01:00", "assignment": "2024-03-04T14:49:30+01:00", "program": 94, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 3, "manager": 65558, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999904895", "ethics_committee": null, "edudract_number": null, "persons": [ "8065-54235-12", "8065-65558-10", "8065-99971-12", "8065-126174-12", "8065-134561-12" ] }, { "id": 8025, "title": { "de": "Gallensäuren verbinden Stoffwechsel mit der Funktion der Granulosazellen", "en": "Bile acids link metabolism to granulosa cell function" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-02-12T01:00:00+01:00", "end_planned": "2024-06-30T02:00:00+02:00", "end_effective": "2025-02-11T01:00:00+01:00", "assignment": "2024-02-06T08:59:10+01:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": 100803, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8025-100803-10" ] }, { "id": 8060, "title": { "de": "Modelling Reproductive Failure with Endometrium-On-A-Chip, acib Projekt ID 98.311", "en": "Modelling Reproductive Failure with Endometrium-On-A-Chip, acib Projekt ID 98.311" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-03-01T10:42:56+01:00", "program": 94, "subprogram": null, "organization": 14064, "category": 10, "type": 10, "partner_function": 2, "manager": 75380, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8060-75380-10" ] }, { "id": 9069, "title": { "de": "Die Rolle von Fra-2/AP-1 in der Homöostase von Endothelzellen - Auswirkungen auf interstitielle Lungenerkrankungen", "en": "Transcription factor Fra-2/AP-1 in endothelial cell homeostasis – implications for interstitial lung disease" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2025-07-04T12:22:55+02:00", "program": null, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 1, "manager": 61540, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9069-61540-10" ] }, { "id": 7894, "title": { "de": "Der Einfluss von Typ I Interferon auf die Pathogenese der Riesenzellarteriitis", "en": "Defining the role of the type I interferon pathway in the pathogenesis of giant cell arteritis " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2027-01-01T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2023-11-21T15:06:00+01:00", "program": null, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 117681, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 87 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7894-117681-10" ] }, { "id": 8151, "title": { "de": "Das intestinale Mikrobiom eines orthotopen und eines ektopen Hepatoblastom Mausmodelles", "en": "The Intestinal Microbiome in an Orthotopic and Ectopic Tumor Murine Model of Hepatoblastoma" }, "short": "Microbiome in Hepatoblastoma Mouse Model", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-08-31T02:00:00+02:00", "assignment": "2024-04-24T15:59:17+02:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 1, "manager": 90375, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8151-50778-12", "8151-90375-10", "8151-97866-12" ] }, { "id": 9072, "title": { "de": "Bioresorbierbare Mg-Fe Implantate in der Knochenheilung", "en": "Adapting bioresorbable Mg-Fe implants in bone healing" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2025-09-01T02:00:00+02:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2028-08-31T02:00:00+02:00", "assignment": "2025-07-07T13:18:31+02:00", "program": 111, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": 98087, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PIN5073823", "ethics_committee": null, "edudract_number": null, "persons": [ "9072-98087-10" ] }, { "id": 8236, "title": { "de": "LYMPHO-CHECK: Bioinformatik und Data-Mining in der Lymphomforschung\r\n ", "en": "LYMPHO-CHECK: Bioinformatics and Data Mining in Lymphoma Research" }, "short": "LYMPHO-CHECK", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-06-03T02:00:00+02:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2029-06-02T02:00:00+02:00", "assignment": "2024-06-03T14:29:51+02:00", "program": 113, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 2, "manager": 94195, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 30", "ethics_committee": null, "edudract_number": null, "persons": [ "8236-94195-10" ] }, { "id": 7917, "title": { "de": "Entwicklung einer Immobilisierungsmethode für ein Compound-Screening basierend auf Fluoreszenzmikroskopie in Fadenwürmern", "en": "Establishing an immobilization method for compound screens based on\r\nfluorescence microscopy in nematodes" }, "short": "Immobilisierung_Compound-Screening_WTZ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2023-12-07T12:13:19+01:00", "program": 207, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 1, "manager": 85069, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7917-85069-10" ] }, { "id": 8235, "title": { "de": "LYMPHO-CHECK: Lymphoma Mausmodelle und funktionelle Genomik", "en": "LYMPHO-CHECK: Lympha mouse models and functional genomics" }, "short": "LYMPHO-CHECK", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-06-03T02:00:00+02:00", "end_planned": "2029-12-31T01:00:00+01:00", "end_effective": "2029-06-02T02:00:00+02:00", "assignment": "2024-06-03T14:29:07+02:00", "program": 113, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 2, "manager": 89979, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 30", "ethics_committee": null, "edudract_number": null, "persons": [ "8235-89979-10" ] }, { "id": 8061, "title": { "de": "Modelling Reproductive Failure with Endometrium-On-A-Chip, acib Projekt ID 98.311\r\n", "en": "Modelling Reproductive Failure with Endometrium-On-A-Chip, acib Projekt ID 98.311\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-03-01T10:49:01+01:00", "program": 94, "subprogram": null, "organization": 14058, "category": 10, "type": 10, "partner_function": 2, "manager": 96172, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8061-96172-10" ] }, { "id": 8681, "title": { "de": "Smart and Federated Open data eXchange of citizen-based data donations for clinical research", "en": "Smart and Federated Open data eXchange of citizen-baseddata donations for clinical research " }, "short": "SmartFOX", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-07-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2025-02-24T16:54:03+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 1, "manager": 99976, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8681-99976-10" ] }, { "id": 8570, "title": { "de": "Erforschung der struktureller und elektrischer Eigenschaften zur in-vitro-axonalen Guidance von 3D-strukturierten photokapazitiven Folien", "en": "Exploring the micro-topographic and galvanotropic cues\r\nfor in-vitro axonal guidance on 3D structured photocapacitive\r\nsubstrates" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-12-18T10:24:31+01:00", "program": 207, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 98848, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8570-98848-10" ] }, { "id": 8144, "title": { "de": "Metabolische Signaturen von T-Zell-Untergruppen als neue diagnostische oder therapeutische Angriffspunkte bei Kollagenose-assoziierten interstitiellen Lungenerkrankungen", "en": "Metabolic signatures of T cell subsets as novel diagnostic or therapeutic\r\ntargets in connective tissue disease-associated interstitial lung disease" }, "short": "T cell metabolism in CTD-ILD", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-04-23T17:42:43+02:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 3, "manager": 95212, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8144-78952-11", "8144-95212-10", "8144-107391-11" ] }, { "id": 7971, "title": { "de": "Elektrophysiologische Charakterisierung der induzierten Zellalterung zur Krebstherapie", "en": "Electrophysiological characterization of the induced senescence in cancer therapy" }, "short": null, "url": null, "abstract": { "de": 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