Project List
List projects.
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GET /v1/research/project/?format=api&offset=300&ordering=-end_effective
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=320&ordering=-end_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=280&ordering=-end_effective", "results": [ { "id": 6368, "title": { "de": "Polycystisches Ovar-Syndrom bei Adoleszenten und jungen Frauen - für eine pathophysiologie-basierte Behandlung", "en": "PCOS IN ADOLESCENT GIRLS AND YOUNG WOMEN: TOWARDS A TREATMENT GUIDED BY PATHOPHYSIOLOGY" }, "short": "SPIOMET4HEALTH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-03-01T01:00:00+01:00", "begin_effective": "2021-04-01T02:00:00+02:00", "end_planned": "2026-02-28T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2021-02-22T12:21:43+01:00", "program": 109, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 4, "manager": 51809, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "899671", "ethics_committee": null, "edudract_number": null, "persons": [ "6368-50909-12", "6368-73713-12", "6368-79611-12", "6368-94754-12", "6368-98005-12", "6368-51809-10", "6368-109041-12", "6368-104611-12" ] }, { "id": 7932, "title": { "de": "European Viral Outbreak Response Alliance", "en": "European Viral Outbreak Response Alliance" }, "short": "EVORA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-09-01T02:00:00+02:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2026-08-31T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2023-12-15T12:05:57+01:00", "program": 210, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7932-51663-10" ] }, { "id": 8107, "title": { "de": "Accelerating datafication for support of EU health priorities, greening of biobanks and integrated approach to “One Health”", "en": "Accelerating datafication for support of EU health priorities, greening of biobanks and integrated approach to “One Health”" }, "short": "EvolveBBMRI", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-09-01T02:00:00+02:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2026-08-31T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-03-22T10:41:14+01:00", "program": 210, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8107-51663-10" ] }, { "id": 8721, "title": { "de": "Schwangerschaftsvergiftung - neuartige Biomarker für die Präeklampsie", "en": " Novel biomarkers for preeclampsia" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-03-03T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-03-12T16:53:33+01:00", "program": null, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 3, "manager": 50909, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8721-50909-10" ] }, { "id": 8645, "title": { "de": "Bile acids ameliorate obesogenic memory", "en": "Bile acids ameliorate obesogenic memory" }, "short": "BAOB", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-02-10T15:52:55+01:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 98847, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8645-98847-10" ] }, { "id": 8188, "title": { "de": "Pilztranslokation über den Darm gemessen durch 1,3-Beta-D-Glukan und seine Rolle in Patient:innen mit Leberzirrhose", "en": "Gut fungal translocation measured by 1,3-Beta-D-Glucan and its role in patients with liver cirrhosis" }, "short": "BDG-Cirrhosis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-08-01T02:00:00+02:00", "begin_effective": "2024-08-01T02:00:00+02:00", "end_planned": "2026-01-01T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-05-07T15:35:19+02:00", "program": null, "subprogram": null, "organization": 29164, "category": 10, "type": 10, "partner_function": 4, "manager": 115781, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 203 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8188-115781-10" ] }, { "id": 9539, "title": { "de": "Patientenbasiertes Immunprofiling und funktionelle Validierung von Matrikin Effekten in akuter Lungenentzündung/ARDS", "en": "Patient-based immunoprofiling and functional validation of matrikin effects in acute pneumonia/ARDS" }, "short": "Matrix-Immune Axis in ARDS ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2026-01-01T01:00:00+01:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2026-01-21T10:06:24+01:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 82595, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9539-82595-10" ] }, { "id": 9483, "title": { "de": "Gestörtes Lipid-Signaling in Typ II Alveolarepithelzellen bei Lungenfibrose", "en": "Lipid signalling impairment in alveolar type II cells in pulmonary fibrosis" }, "short": "Lipid-Signaling_Typ II Alveloarepithelz", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2025-12-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-12-15T09:54:58+01:00", "program": null, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 57409, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9483-57409-10", "9483-133023-12" ] }, { "id": 8140, "title": { "de": "Entschlüsselung von Alzheimer: \r\nTRPC1 als zentrale Figur bei Protein-Entfaltung und Cholesterin-Biosynthese\r\n", "en": "Deciphering Alzheimer's: \r\nTRPC1 as a central player in protein unfolding and cholesterol biosynthesis" }, "short": null, "url": null, "abstract": { "de": "Hintergrund: Die Alzheimer-Krankheit (AD) ist eine irreversible und tödliche Form von Demenz, unterteilt in sporadische (SAD) und familiäre AD (FAD). FAD, mit frühem Beginn aufgrund spezifischer Genmutationen, steht im Gegensatz zu SAD, das einen späten Beginn und eine unklare Ursache aufweist. Die Ca2+-Homöostase- Hypothese von SAD legt nahe, dass eine frühzeitige Ca2+-Dysregulation mit der Fehlfaltung von Proteinen und der Anreicherung von Cholesterin einhergeht. Das endoplasmatische Retikulum (ER) ist entscheidend für die Regulation des intrazellulären Ca2+, die Verarbeitung von Proteinen und die Lipid-Biosynthese. Die Familie der transienten Rezeptorpotenzial-Kanäle (TRPC1-7) umfasst TRPC1, der im Hippocampus stark exprimiert wird. Während TRPC2-7 ausschließlich in der Plasmamembran gefunden werden, befindet sich TRPC1 auch in der ER- Membran.\r\nHypothese: TRPC1 könnte an der Regulation von Ca2+, der Synthese von Proteinen und Cholesterin im ER beteiligt sein.\r\nErgebnisse: Vorläufige Experimente zeigten, dass TRPC1 den Ca2+-Leck aus dem ER signifikant verstärkte, den Cholesterinspiegel in TRPC1-transfizierten HEK293-Zellen erhöhte, den Cholesterinspiegel in den Hippocampi transgener Mäuse im Alter veränderte und die Expression von Transkriptionsfaktoren beeinflusste, die an der Proteinfaltung beteiligt sind.\r\nFazit: Eine weitere Erforschung der Rolle von TRPC1 im ER könnte ihn als potenzielles pharmazeutisches Ziel in der AD-Behandlung etablieren.", "en": "Background: Alzheimer’s disease (AD) is an irreversible and fatal form of dementia, divided into sporadic (SAD) and familial AD (FAD). FAD, with early onset due to specific gene mutations, contrasts SAD, with late onset and an unclear cause. The Ca2+ homeostasis hypothesis of SAD suggests early Ca2+ dyshomeostasis links to protein misfolding and cholesterol accumulation. The endoplasmic reticulum (ER) is crucial, managing intracellular Ca2+, protein processing, and lipid biosynthesis. The transient receptor potential canonical family (TRPC1-7) includes TRPC1, highly expressed in the hippocampus. While TRPC2-7 target the plasma membrane, TRPC1 is also found in the ER membrane.\r\nHypothesis: TRPC1 may be involved in Ca2+ handling, protein, and cholesterol synthesis in the ER.\r\nResults: Preliminary experiments showed TRPC1 increased Ca2+ leak from the ER, elevated cholesterol in TRPC1- transfected HEK293 cells, altered cholesterol levels in hippocampi from aged transgenic mice, and affected expression of transcription factors involved in protein folding.\r\nConclusion: Further exploring TRPC1 role in the ER could establish it as a potential pharmaceutical target in AD treatment." }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2025-02-28T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-04-16T14:17:18+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 90337, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8140-90337-10", "8140-116421-12", "8140-122690-12" ] }, { "id": 6427, "title": { "de": "Effekte einer thyreostatischen Therapie auf Knochenmikroarchitektur und Body Composition bei Morbus Basedow: eine longitudinale Kohortenstudie", "en": "Effects of antithyroid therapy on bone microarchitecture and body composition in Graves’ disease: a longitudinal cohort study" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-09-01T02:00:00+02:00", "begin_effective": "2020-09-01T02:00:00+02:00", "end_planned": "2021-09-01T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2021-01-28T13:58:54+01:00", "program": null, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 1, "manager": 85701, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1565 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6427-85701-10" ] }, { "id": 8636, "title": { "de": "LUMES: Lichtaktive Mikropartikel bei degnerativen Augenerkrankungen", "en": "LUMES: Light-Utilizing Microparticles for Eye Sight" }, "short": "LUMES:", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-02-03T14:38:00+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 99325, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8636-99325-10" ] }, { "id": 6015, "title": { "de": "CETOCOEN Excellence", "en": "CETOCOEN Excellence" }, "short": "CETOCOEN Excellence", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2020-01-07T14:17:10+01:00", "program": 109, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51449, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6015-51449-10", "6015-99976-12", "6015-133220-12" ] }, { "id": 5704, "title": { "de": "Probiotische Modulation der Darmflora in PatientInnen mit Leberzirrhose und Lanzeiteinnahme von Protonenpumpenhemmer", "en": "Probiotic modulation of intestinal microbiota of cirrhotic patients with long-term PPI use " }, "short": "PPI-PRB", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-06-01T02:00:00+02:00", "begin_effective": "2019-03-01T01:00:00+01:00", "end_planned": "2019-05-31T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2019-02-20T10:12:04+01:00", "program": null, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 81091, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-41", "ethics_committee": null, "edudract_number": null, "persons": [ "5704-81091-10" ] }, { "id": 6407, "title": { "de": "Einzelzell-RNA-Sequenzierung von Speicheldrüsenbiopsien von Patient*innen mit primärem Sjögren-Syndrom", "en": "Single cell RNA sequencing of salivary gland biopsies of patients with primary Sjögren‘s Syndrome" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-01-01T01:00:00+01:00", "begin_effective": "2021-01-01T01:00:00+01:00", "end_planned": "2022-01-01T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2021-01-12T15:01:07+01:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": 105947, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 87 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6407-105947-10", "6407-106927-12", "6407-111407-12" ] }, { "id": 8504, "title": { "de": "European Federation for Cancer Images", "en": "European Federation for Cancer Images" }, "short": "EUCAIM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2024-07-01T02:00:00+02:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-11-19T14:02:04+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 1, "manager": 99976, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8504-99976-10", "8504-133200-12", "8504-133281-12" ] }, { "id": 8272, "title": { "de": "Stärkung der Immuntherapie bei nichtkleinzelligem Lungenkrebs", "en": "Boosting immunotherapy in non-small cell lung cancer" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-08-01T02:00:00+02:00", "begin_effective": "2024-08-01T02:00:00+02:00", "end_planned": "2026-08-01T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-06-21T11:36:43+02:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 111070, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1375 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8272-111070-10" ] }, { "id": 7933, "title": { "de": "INTERnational Cooperation of high containment research infrastructures: from Epidemic Preparedness TO\r\nResponse", "en": "INTERnational Cooperation of high containment research infrastructures: from Epidemic Preparedness TO\r\nResponse" }, "short": "INTERCEPTOR", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-09-01T02:00:00+02:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2026-08-31T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2023-12-15T12:06:13+01:00", "program": 210, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7933-51663-10" ] }, { "id": 6155, "title": { "de": "Identifizierung von Interaktionen akuter Leukämiezellen mit der Knochenmarksnische.", "en": "Identification of leukemic niche interactions in acute myeloid leukemia" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-07-01T02:00:00+02:00", "end_planned": "2022-03-31T02:00:00+02:00", "end_effective": "2026-12-30T01:00:00+01:00", "assignment": "2020-06-15T13:54:55+02:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 50747, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6155-50747-10" ] }, { "id": 9577, "title": { "de": "Er: YAG-Laser vs. rotierende Instrumente – Einfluss\r\nder Erfahrung auf Effizienz, Oberflächenqualität und\r\nPräferenz bei der Entfernung von Veneers", "en": "Er: YAG laser vs. rotary instruments - influence\r\nof experience on efficiency, surface quality and\r\npreference when removing veneers" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2026-12-01T01:00:00+01:00", "end_effective": "2026-12-01T01:00:00+01:00", "assignment": "2026-02-02T12:41:25+01:00", "program": null, "subprogram": null, "organization": 14111, "category": 10, "type": 10, "partner_function": 1, "manager": 126234, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2591 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9577-126234-10" ] }, { "id": 6760, "title": { "de": "Apolipoprotein AI(apo-AI) Peptid-Lipid Komplexe", "en": "Apolipoprotein AI(apo-AI) Mimetic Peptide Lipid Assemblies" }, "short": "AAMLA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-01-01T01:00:00+01:00", "begin_effective": "2022-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-11-30T01:00:00+01:00", "assignment": "2021-10-22T11:40:29+02:00", "program": 111, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 83104, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I5703", "ethics_committee": null, "edudract_number": null, "persons": [ "6760-83104-10", "6760-83104-12", "6760-107231-12" ] } ] }