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GET /v1/research/project/?format=api&offset=280
{ "count": 2266, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=300", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=260", "results": [ { "id": 9538, "title": { "de": "Charakterisierung von Biglykans Rolle im vaskulären Umbau und der pulmonalen arteriellen Hypertonie - Ein neuer therapeutischer Angriffspunkt?", "en": "Characterization of biglycans role in vascular remodelling and pulmonary\r\narterial hypertension – A new therapeutic target?" }, "short": "BiPAH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-10-06T02:00:00+02:00", "begin_effective": "2025-10-06T02:00:00+02:00", "end_planned": "2026-10-05T02:00:00+02:00", "end_effective": "2026-10-05T02:00:00+02:00", "assignment": "2026-01-19T15:12:52+01:00", "program": null, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 3, "manager": 114963, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9538-114963-10" ] }, { "id": 3368, "title": { "de": "Auswirkung von Verkehrslärm im Freifeld", "en": "Evaluation of the influence of naturalistic road and rail traffic noise on both psychological and physiological parameters in the free field" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-05-01T02:00:00+02:00", "begin_effective": "2013-10-01T02:00:00+02:00", "end_planned": "2014-04-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2013-09-09T16:52:17+02:00", "program": 72, "subprogram": null, "organization": 14024, "category": 10, "type": 10, "partner_function": 2, "manager": 51845, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25747", "ethics_committee": null, "edudract_number": null, "persons": [ "3368-51845-10" ] }, { "id": 9539, "title": { "de": "Patientenbasiertes Immunprofiling und funktionelle Validierung von Matrikin Effekten in akuter Lungenentzündung/ARDS", "en": "Patient-based immunoprofiling and functional validation of matrikin effects in acute pneumonia/ARDS" }, "short": "Matrix-Immune Axis in ARDS ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2026-01-01T01:00:00+01:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2026-01-21T10:06:24+01:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 82595, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9539-82595-10" ] }, { "id": 4093, "title": { "de": "Liquid Biopsies Datenanalyse", "en": "Liquid biopsies data analysis" }, "short": "LIBIDA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-03-01T01:00:00+01:00", "begin_effective": "2015-10-01T02:00:00+02:00", "end_planned": "2017-02-28T01:00:00+01:00", "end_effective": "2017-09-30T02:00:00+02:00", "assignment": "2015-09-08T15:31:48+02:00", "program": 60, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 3, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "850700", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5853, "title": { "de": "Klassifizierung von Brustkrebs mittels \"liquid biopsies\"", "en": "Breast cancer liquid biopsy stratification" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-04-01T02:00:00+02:00", "begin_effective": "2019-10-01T02:00:00+02:00", "end_planned": "2022-03-31T02:00:00+02:00", "end_effective": "2023-10-31T01:00:00+01:00", "assignment": "2019-07-11T10:35:55+02:00", "program": null, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI 764", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 7367, "title": { "de": "Krebs und Alterung Flüssigchromatindiagnostik", "en": "Cancer and Aging Liquid Chromatin Diagnostics" }, "short": "CALC Dx", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-04-01T02:00:00+02:00", "begin_effective": "2023-04-01T02:00:00+02:00", "end_planned": "2024-07-04T02:00:00+02:00", "end_effective": "2024-09-30T02:00:00+02:00", "assignment": "2023-02-02T10:09:22+01:00", "program": 117, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 4, "manager": 77970, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999899093", "ethics_committee": null, "edudract_number": null, "persons": [ "7367-77970-10" ] }, { "id": 8799, "title": { "de": "Trauma & Herz", "en": "Trauma & Heart" }, "short": "Trauma & Herz", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-05-01T02:00:00+02:00", "begin_effective": "2025-05-01T02:00:00+02:00", "end_planned": "2026-04-30T02:00:00+02:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2025-04-23T13:51:00+02:00", "program": null, "subprogram": null, "organization": 29447, "category": 10, "type": 10, "partner_function": 4, "manager": 75522, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8799-75522-10" ] }, { "id": 5328, "title": { "de": "Das Mikrobiom der Harnblase bei Frühgeburtlichkeit – Eine Pilotstudie", "en": "The urine microbiome and preterm complications - a pilot study" }, "short": "UMIC", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-05-01T02:00:00+02:00", "begin_effective": "2018-05-01T02:00:00+02:00", "end_planned": "2018-12-01T01:00:00+01:00", "end_effective": "2018-12-01T01:00:00+01:00", "assignment": "2018-04-05T17:30:45+02:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": 90021, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5328-90021-10" ] }, { "id": 5085, "title": { "de": "Mikrobiom Graz", "en": "Microbiome Graz" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-09-01T02:00:00+02:00", "begin_effective": "2017-09-01T02:00:00+02:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2017-10-11T10:52:53+02:00", "program": null, "subprogram": "Subvention Kulturamt Graz", "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": 90021, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5085-90021-10" ] }, { "id": 5733, "title": { "de": "Analyse der antibakteriellen Wirkung von Lactobacillus casei Rhamnosus (LCR35) Überstand auf Helicobacter pylori", "en": "Analyse der antibakteriellen Wirkung von Lactobacillus casei Rhamnosus (LCR35) Überstand auf Helicobacter pylori" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-03-01T01:00:00+01:00", "begin_effective": "2019-03-01T01:00:00+01:00", "end_planned": "2019-05-31T02:00:00+02:00", "end_effective": "2019-06-30T02:00:00+02:00", "assignment": "2019-03-11T15:12:17+01:00", "program": null, "subprogram": null, "organization": 14023, "category": 30, "type": 10, "partner_function": 4, "manager": 90021, "contact": null, "status": 2, "research": 2, "grant": 20, "event": null, "study": null, "language": null, "funders": [ 2492 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5733-90021-10" ] }, { "id": 4675, "title": { "de": "Die klinisch-forensische Untersuchungsstelle", "en": "The clinical forensic care unit" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-01-01T01:00:00+01:00", "begin_effective": "2016-01-01T01:00:00+01:00", "end_planned": "2016-12-31T01:00:00+01:00", "end_effective": "2017-06-30T02:00:00+02:00", "assignment": "2016-11-02T10:53:39+01:00", "program": null, "subprogram": null, "organization": 14019, "category": 10, "type": 10, "partner_function": 4, "manager": 90131, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4675-90131-10" ] }, { "id": 6659, "title": { "de": "Antikörperrepertoires gegen das menschliche Mikrobiom", "en": "Antibody repertoires against the microbiome" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-07-19T02:00:00+02:00", "begin_effective": "2021-07-19T02:00:00+02:00", "end_planned": "2022-07-18T02:00:00+02:00", "end_effective": "2022-07-31T02:00:00+02:00", "assignment": "2021-08-02T11:19:26+02:00", "program": 69, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "J 4256", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2384, "title": { "de": "Mobile Teledermatologie in der Behandlung von Akne-Patienten", "en": "Use of Mobile Teledermatology in the Care of Acne Patients" }, "short": "Mobile Acne Care", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-01-01T01:00:00+01:00", "begin_effective": "2011-04-01T02:00:00+02:00", "end_planned": "2011-12-31T01:00:00+01:00", "end_effective": "2012-12-31T01:00:00+01:00", "assignment": "2011-01-24T15:38:08+01:00", "program": 79, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 51711, "contact": 51711, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2384-51711-10" ] }, { "id": 2406, "title": { "de": "Adipokine Visfatin und Chemerin im Kindes- und Jugendalter", "en": "The adipokines visfatin and chemerin in childhood and adolescence" }, "short": "ADIPOKINE VISFATIN CHEMERIN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-10-01T02:00:00+02:00", "begin_effective": "2011-03-01T01:00:00+01:00", "end_planned": "2011-10-01T02:00:00+02:00", "end_effective": "2011-12-30T01:00:00+01:00", "assignment": "2011-02-15T12:46:08+01:00", "program": null, "subprogram": null, "organization": 14091, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2641, "title": { "de": "Einfluss von Empfänger- und Spender-Cytochrom P450 3A5 Genotypen auf die Pharmakokinetik von Tacrolimus bei PatientInnen nach Lebertransplantation", "en": "Einfluss von Empfänger- und Spender-Cytochrom P450 3A5 Genotypen auf die Pharmakokinetik von Tacrolimus bei PatientInnen nach Lebertransplantation" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-10-01T02:00:00+02:00", "begin_effective": "2011-11-01T01:00:00+01:00", "end_planned": "2013-10-31T01:00:00+01:00", "end_effective": "2012-06-30T02:00:00+02:00", "assignment": "2011-11-18T13:45:47+01:00", "program": null, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": 58323, "contact": 58323, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2641-58323-10" ] }, { "id": 9540, "title": { "de": "Umweltfaktoren für den Schlaf: Ein bilateraler Ansatz für Review, Analyse und Forschungsplanung", "en": "Environmental determinants of sleep: A bilateral approach to review, research, and analytical planning" }, "short": "Environmental determinants of sleep", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2026-01-01T01:00:00+01:00", "end_planned": "2027-12-31T01:00:00+01:00", "end_effective": "2027-12-31T01:00:00+01:00", "assignment": "2026-01-21T13:12:01+01:00", "program": 201, "subprogram": null, "organization": 14024, "category": 10, "type": 10, "partner_function": 1, "manager": 131598, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9540-131598-10" ] }, { "id": 8362, "title": { "de": "MEK Inhibition bei RAS-mutierter/EZH2-inaktivierter CMML", "en": "MEK inhibition in RAS-mutated/EZH2-inactivated CMML" }, "short": null, "url": null, "abstract": { "de": "Forschungskontext/theoretischer Rahmen:\r\nDie chronische myelomonozytäre Leukämie (CMML) ist eine aggressive hämatopoetische Neoplasie, die häufig auf Aberrationen zurückzuführen ist, die die RAS-Onkogene verändern (RASmut). Leider sind die derzeitigen therapeutischen Ansätze für RASmut-CMML-Patienten unzureichend. Wir zeigen, dass RASmut bei CMML häufig mit inaktivierenden Aberrationen des epigenetischen Modifikators EZH2 (EZH2inact) einhergeht. In-vitro-Zellkulturstudien zeigen, dass myeloische Zellen mit RASmut/EZH2inact eine Hyperaktivierung der RAS-Signaltransduktion aufweisen und besonders stark auf eine RAS-MAPK/ERK-Inhibition mit MEK-Inhibitoren (MEKi) reagieren.\r\n\r\nHypothesen/Forschungsfragen/Zielsetzungen:\r\nForschungsfrage: \r\nWir fragen, ob unterschiedliche pharmakologische Ansätze therapeutisch auf RASmut/EZH2inact CMML abzielen können.\r\nHypothese: \r\nWir stellen die Hypothese auf, dass RASmut und EZH2inact synergistisch RAS-Signalwege in CMML aktivieren und eine erhöhte Empfindlichkeit gegenüber MEKi verleihen.\r\nZielsetzungen: \r\nDurch die strategische Einbindung unserer Biobank mit klinisch gut annotierten Patientenproben in modernste In-vitro- und In-vivo-Ansätze werden wir zunächst unser Wissen über die Auswirkungen des gemeinsamen Auftretens von RASmut/EZH2inact auf die RAS-MAPK/ERK-Signalübertragung bei CMML erweitern. Anschließend werden wir die MEKi-Therapie in diesen Modellen analysieren und nach einer bevorzugten Empfindlichkeit des RASmut/EZH2inact-Genotyps fragen. Schließlich werden wir die Auswirkungen von MEKi auf RASmut/EZH2inact CMML-Leukämie-Stammzellen (LSC) und die klonale Evolution untersuchen. \r\n\r\nHerangehensweise/Methoden:\r\nWir werden zunächst die Auswirkungen von EZH2inact auf die Aktivierung der RASmut-Signalübertragung in transgenen In-vivo-Mausmodellen, primären CMML-Patientenproben und von Patienten stammenden Xenografts (PDX) untersuchen. Diese Analysen werden die durchflusszytometrische Bewertung des RAS-signalisings in hämatopoetischen Stamm- und Vorläuferzellen (HSPC) und LSC umfassen. Anschließend werden wir diese Modelle verwenden, um die Auswirkungen des gleichzeitigen Auftretens von RASmut/EZH2inact auf MEKi zu bewerten. Letztendlich wollen wir das therapeutische Potenzial von MEKi zur Heilung von RASmut/EZH2inact CMML bewerten. Daher werden wir die Auswirkungen der MEKi-Behandlung auf RASmut/EZH2inact-HSPC-Kompartimente, CMML-LSC und die klonale Evolution der CMML untersuchen. \r\n\r\nGrad der Originalität/Innovation:\r\nDie gezielte Beeinflussung der aberranten RAS-Signalübertragung ist seit Jahrzehnten ein wichtiger Forschungsschwerpunkt. Obwohl seit kurzem direkte RAS-Inhibitoren der nächsten Generation zur Verfügung stehen, war der therapeutische Nutzen für RASmut-CMML-Patienten begrenzt. Dieses Projekt untersucht einen neuartigen Ansatz und schlägt vor, dass eine erfolgreiche molekular gesteuerte Behandlung bei RASmut CMML den Einfluss von koexistierenden und funktionell interagierenden Läsionen berücksichtigen muss.\r\n\r\nBeteiligte Hauptforscher:\r\nArmin Zebisch, der über eine langjährige Erfahrung auf dem Gebiet der RAS-Signalübertragung bei myeloischen Neoplasien verfügt, wird der Hauptforscher sein. Er wird von klinischen Hämatologen und Grundlagenforschern unterstützt, die über profunde Kenntnisse der CMML und der in diesem Projekt verwendeten Modelle verfügen. Ein Doktorand und ein Techniker werden sein Laborteam bei der Durchführung dieses Projekts unterstützen.\r\n", "en": "Wider research context/theoretical framework:\r\nChronic myelomonocytic leukemia (CMML) is an aggressive hematopoietic neoplasia and is frequently driven by aberrations modifying the RAS oncogenes (RASmut). Unfortunately, current therapeutic approaches for RASmut CMML patients are insufficient. We demonstrate that RASmut in CMML often co-occur with inactivating aberrations of the epigenetic modifier EZH2 (EZH2inact). In-vitro cell culture studies reveal that RASmut/EZH2inact myeloid cells exhibit RAS-signaling hyperactivation and might be preferentially sensitive to RAS-MAPK/ERK inhibition with MEK inhibitors (MEKi).\r\n\r\nHypotheses/research questions/objectives:\r\nResearch question: \r\nWe ask whether distinctive pharmacological approaches can therapeutically target RASmut/EZH2inact CMML.\r\nHypothesis:\r\nWe hypothesize that RASmut and EZH2inact synergistically activate RAS-signaling pathways in CMML and confer increased sensitivity to MEKi.\r\nObjectives: \r\nBy strategically incorporating our biobank with clinically well-annotated patient specimens into state-of-the-art in-vitro and in-vivo approaches, we will initially extend our knowledge on the effects of RASmut/EZH2inact co-occurrence on RAS-MAPK/ERK signaling in CMML. We will then analyze MEKi therapy within these models and ask for preferential sensitivity in the RASmut/EZH2inact genotype. Ultimately, we will assess the effects of MEKi on RASmut/EZH2inact CMML-leukemic stem cells (LSC) and clonal evolution. \r\n\r\nApproach/methods:\r\nWe will initially elaborate on the effects of EZH2inact on the activation of RASmut-signaling in transgenic murine in-vivo models, primary CMML patient specimens, and patient-derived xenografts (PDX). These analyses will include the flow-cytometry-based assessment of RAS-signaling in hematopoietic stem and progenitor cells (HSPC) and LSC. We will then use these models to assess the effects of RASmut/EZH2inact co-occurrence on MEKi. Ultimately, we will aim to assess the therapeutic potential of MEKi to cure RASmut/EZH2inact CMML. Therefore, we will study the effects of MEKi treatment on RASmut/EZH2inact HSPC compartments, CMML-LSC and clonal evolution of CMML. \r\nLevel of originality/innovation\r\nTargeting aberrant RAS signaling has been a significant focus of research for the last decades. Despite the recent advent of direct next-generation RAS inhibitors, the therapeutic benefit for RASmut CMML patients was limited. This project assesses a novel approach and proposes that successful molecular-guided treatment in RASmut CMML must consider the influence of co-existing and functionally interacting lesions.\r\nPrimary researchers involved\r\nArmin Zebisch has a strong track record on RAS-signaling in myeloid neoplasms and will be the principal investigator. He will be supported by clinical hematologists and basic researchers with profound expertise in CMML and the models used within this project. A PhD student and technician will further support his lab team in executing this project.\r\n" }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2028-01-01T01:00:00+01:00", "end_effective": "2029-12-31T01:00:00+01:00", "assignment": "2024-08-21T15:56:58+02:00", "program": 72, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 57402, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PAT 1753824", "ethics_committee": null, "edudract_number": null, "persons": [ "8362-57402-10", "8362-97430-12", "8362-97983-12", "8362-50116-12" ] }, { "id": 2842, "title": { "de": "Risiko der Entwicklung einer altersabhängigen Makuladegeneration in Abhängigkeit des CFH Tyr402His Genpolymorphismus bei PatientInnen nach Lebertransplantation", "en": "Influence of CFH Tyr402His gene polymorphism on risk for age-related macular degneration in patients after liver transplantation" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-04-01T02:00:00+02:00", "begin_effective": "2012-05-01T02:00:00+02:00", "end_planned": "2014-04-01T02:00:00+02:00", "end_effective": "2013-03-30T01:00:00+01:00", "assignment": "2012-04-20T14:57:04+02:00", "program": null, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": 58323, "contact": 58323, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2842-58323-10" ] }, { "id": 2485, "title": { "de": "Einfluss des Prolaktinrezeptors und steroidaler Hormonrezeptoren auf die Biologie des kolorektalen Karzinoms und korrespondierender Metastasen", "en": "Influence of prolactin receptor and steroidal hormone receptors on the biology of colorectal carcinoma and corresponding metastases" }, "short": "PROLACTION RECEPTOR COLORECT CARC", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-05-01T02:00:00+02:00", "begin_effective": "2011-05-01T02:00:00+02:00", "end_planned": "2013-05-01T02:00:00+02:00", "end_effective": "2013-05-01T02:00:00+02:00", "assignment": "2011-05-26T14:07:23+02:00", "program": null, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": 50039, "contact": 50039, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2485-50039-10" ] }, { "id": 3002, "title": { "de": "Dkk-1 im peripheren Blut zur Unterscheidung von intrazerebraler Blutung und ischämischem Insult", "en": "Dkk-1 in peripheral blood to discriminate between intracerebral hemorrhaghe and ischemic stroke" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-11-01T01:00:00+01:00", "end_planned": "2012-03-31T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2012-10-16T15:26:36+02:00", "program": null, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 53287, "contact": 53287, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3002-53287-10" ] } ] }