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GET /v1/research/project/?format=api&offset=260&ordering=-begin_effective
{ "count": 2244, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=280&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=240&ordering=-begin_effective", "results": [ { "id": 8252, "title": { "de": "Neonatologischer Lungenultraschall bei Neugeborenen 15 Minuten nach der Geburt, um den Bedarf und Dauer einer Atemunterstützung vorherzusagen", "en": "Neonatologist-performed lung ultrasound (NPLUS) in neonates 15 minutes after birth to predict requirement for respiratory support persisting more than 1 hour" }, "short": "NPLUS in neonates", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-02-01T01:00:00+01:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2026-02-01T01:00:00+01:00", "end_effective": "2025-04-30T02:00:00+02:00", "assignment": "2024-06-13T13:19:26+02:00", "program": null, "subprogram": null, "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": 86558, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8252-79516-11", "8252-86558-10" ] }, { "id": 8561, "title": { "de": "Gewaltambulanz\r\nder Medizinischen Universität Graz und Konzept für die\r\nflächendeckende Versorgung", "en": "-" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-12-12T14:44:55+01:00", "program": null, "subprogram": null, "organization": 14019, "category": 10, "type": 10, "partner_function": 4, "manager": 115441, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8561-115441-10" ] }, { "id": 7983, "title": { "de": "Gewebe-infiltrierende Lymphozyten - Direkte Evaluierung der Rezeptoren", "en": "Tissue-infiltrating Lymphocytes - Direct Evaluation of Receptors" }, "short": "TIL-DER", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-01-19T11:58:34+01:00", "program": 117, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 3, "manager": 98567, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999909640", "ethics_committee": null, "edudract_number": null, "persons": [ "7983-98567-10" ] }, { "id": 8106, "title": { "de": "Klonale Dominanz in Splicingfaktor mutierten myeloischen Neoplasien: Beitrag deregulierter Immunsignalwege", "en": "Aberrant immune signaling and clonal dominance in splicing factor mutant myeloid malignancies" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2026-02-28T01:00:00+01:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-03-21T14:19:14+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 50747, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8106-50747-10", "8106-108881-12" ] }, { "id": 8069, "title": { "de": "Erforschung der Immunseneszenz bei Multipler Sklerose", "en": "Investigating immunosenescence in Multiple Sclerosis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-03-30T01:00:00+01:00", "end_effective": "2025-06-30T02:00:00+02:00", "assignment": "2024-03-06T16:48:57+01:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": 95212, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2539 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8069-57435-11", "8069-78952-11", "8069-95212-10", "8069-111529-12" ] }, { "id": 8104, "title": { "de": "Digitale Zwilling für die Therapie von Vorhofflimmern", "en": "Digital Twins for Personalized Atrial Fibrillation Care" }, "short": "TwinCare-AF", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2026-03-31T02:00:00+02:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-03-20T10:40:25+01:00", "program": 209, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 122514, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8104-122514-10" ] }, { "id": 7710, "title": { "de": "Metabolomics bei PH: Erkennung und Risikovorhersage", "en": "Metabolomics in PH: detection, risk prediction, monitoring" }, "short": "GRAPH-M", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2027-12-31T01:00:00+01:00", "end_effective": "2028-03-31T02:00:00+02:00", "assignment": "2023-08-08T13:40:35+02:00", "program": 108, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 54345, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI 1153", "ethics_committee": null, "edudract_number": null, "persons": [ "7710-91409-12", "7710-73404-12", "7710-115981-12", "7710-54345-10" ] }, { "id": 8338, "title": { "de": "Zeitabhängige Änderung der Inzidenz und der Überlebensrate von PatientInnen mit Weichteil- und Knochensarkomen in Österreich. Eine Populations-basierte epidemiologische Studie.", "en": "Time-dependent change in incidence and survival rate of patients with soft tissue and bone sarcoma across Austria. A population-based epidemiologic study." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-03-31T02:00:00+02:00", "end_effective": "2025-03-31T02:00:00+02:00", "assignment": "2024-08-09T11:39:56+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 4, "manager": 95171, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": "FIF-A 16-0299/2024-0001", "ethics_committee": null, "edudract_number": null, "persons": [ "8338-95171-10" ] }, { "id": 8137, "title": { "de": "MindLeap: Kognitionsmessung im Zeitalter von Virtual Reality", "en": "MindLeap: Measuring cognition in the age of virtual reality" }, "short": "MindLeap", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-04-30T02:00:00+02:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-04-11T14:57:53+02:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 3, "manager": 79733, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8137-79733-10" ] }, { "id": 8066, "title": { "de": "Digitalisierung von innovativen Pflegeprozessen\r\nzur Entlastung und Befähigung von Pflegenden\r\n", "en": "Digitalisation of Innovative Care Processes\r\nto Unburden and Empower Nurses" }, "short": "N!CA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2028-02-29T01:00:00+01:00", "end_effective": "2028-02-29T01:00:00+01:00", "assignment": "2024-03-04T14:49:46+01:00", "program": 94, "subprogram": null, "organization": 14509, "category": 10, "type": 10, "partner_function": 2, "manager": 63683, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999904895", "ethics_committee": null, "edudract_number": null, "persons": [ "8066-63683-10" ] }, { "id": 8140, "title": { "de": "Entschlüsselung von Alzheimer: \r\nTRPC1 als zentrale Figur bei Protein-Entfaltung und Cholesterin-Biosynthese\r\n", "en": "Deciphering Alzheimer's: \r\nTRPC1 as a central player in protein unfolding and cholesterol biosynthesis" }, "short": null, "url": null, "abstract": { "de": "Hintergrund: Die Alzheimer-Krankheit (AD) ist eine irreversible und tödliche Form von Demenz, unterteilt in sporadische (SAD) und familiäre AD (FAD). FAD, mit frühem Beginn aufgrund spezifischer Genmutationen, steht im Gegensatz zu SAD, das einen späten Beginn und eine unklare Ursache aufweist. Die Ca2+-Homöostase- Hypothese von SAD legt nahe, dass eine frühzeitige Ca2+-Dysregulation mit der Fehlfaltung von Proteinen und der Anreicherung von Cholesterin einhergeht. Das endoplasmatische Retikulum (ER) ist entscheidend für die Regulation des intrazellulären Ca2+, die Verarbeitung von Proteinen und die Lipid-Biosynthese. Die Familie der transienten Rezeptorpotenzial-Kanäle (TRPC1-7) umfasst TRPC1, der im Hippocampus stark exprimiert wird. Während TRPC2-7 ausschließlich in der Plasmamembran gefunden werden, befindet sich TRPC1 auch in der ER- Membran.\r\nHypothese: TRPC1 könnte an der Regulation von Ca2+, der Synthese von Proteinen und Cholesterin im ER beteiligt sein.\r\nErgebnisse: Vorläufige Experimente zeigten, dass TRPC1 den Ca2+-Leck aus dem ER signifikant verstärkte, den Cholesterinspiegel in TRPC1-transfizierten HEK293-Zellen erhöhte, den Cholesterinspiegel in den Hippocampi transgener Mäuse im Alter veränderte und die Expression von Transkriptionsfaktoren beeinflusste, die an der Proteinfaltung beteiligt sind.\r\nFazit: Eine weitere Erforschung der Rolle von TRPC1 im ER könnte ihn als potenzielles pharmazeutisches Ziel in der AD-Behandlung etablieren.", "en": "Background: Alzheimer’s disease (AD) is an irreversible and fatal form of dementia, divided into sporadic (SAD) and familial AD (FAD). FAD, with early onset due to specific gene mutations, contrasts SAD, with late onset and an unclear cause. The Ca2+ homeostasis hypothesis of SAD suggests early Ca2+ dyshomeostasis links to protein misfolding and cholesterol accumulation. The endoplasmic reticulum (ER) is crucial, managing intracellular Ca2+, protein processing, and lipid biosynthesis. The transient receptor potential canonical family (TRPC1-7) includes TRPC1, highly expressed in the hippocampus. While TRPC2-7 target the plasma membrane, TRPC1 is also found in the ER membrane.\r\nHypothesis: TRPC1 may be involved in Ca2+ handling, protein, and cholesterol synthesis in the ER.\r\nResults: Preliminary experiments showed TRPC1 increased Ca2+ leak from the ER, elevated cholesterol in TRPC1- transfected HEK293 cells, altered cholesterol levels in hippocampi from aged transgenic mice, and affected expression of transcription factors involved in protein folding.\r\nConclusion: Further exploring TRPC1 role in the ER could establish it as a potential pharmaceutical target in AD treatment." }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2025-02-28T01:00:00+01:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-04-16T14:17:18+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 90337, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8140-90337-10", "8140-116421-12", "8140-122690-12" ] }, { "id": 7934, "title": { "de": "Maschinelles Hören im Kreißsaal: Pilotstudie zur automatischen Evaluierung der neonatalen Lungenfunktion anhand des ersten Schreis", "en": "Maschinelles Hören im Kreißsaal: Pilotstudie zur automatischen Evaluierung der neonatalen Lungenfunktion anhand des ersten Schreis" }, "short": "Maschinelles Hören im Kreißsaal", "url": null, "abstract": { "de": "Die in den ersten Lebensminuten produzierten Laute von Neugeborenen sorgen dafür, dass ein Teil der Ausatemluft vom Kehlkopf zurückpendelt und so das Fruchtwasser aus der Lunge in das umliegende Gewebe presst. Aufgrund unterschiedlich fortgeschrittener Lungenentwicklung gibt es mitunter hörbare Unterschiede zwischen Termin- und Frühgeborenen. Dieses Projekt evaluiert die Durchführbarkeit von standardisierten Tonaufnahmen in der Geburtssituation. Basierend auf Pilotdaten erfolgt erstmals eine umfassende Beschreibung akustischer Merkmale der ersten Laute von Termin- und Frühgeborenen sowie die Validierung künstlicher Intelligenz zur Einschätzung neonataler Lungenfunktion.", "en": null }, "begin_planned": "2024-01-15T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2025-01-14T01:00:00+01:00", "end_effective": "2025-05-31T02:00:00+02:00", "assignment": "2023-12-15T12:07:02+01:00", "program": null, "subprogram": null, "organization": 14068, "category": 10, "type": 10, "partner_function": 4, "manager": 79651, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7934-79651-10", "7934-91531-12", "7934-77049-12", "7934-125014-12" ] }, { "id": 8065, "title": { "de": "Digitalisierung von innovativen Pflegeprozessen \r\nzur Entlastung und Befähigung von Pflegekräften", "en": "Digitalisation of Innovative Care Processes \r\nto Unburden and Empower Nurses\r\n" }, "short": "N!CA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2027-12-31T01:00:00+01:00", "end_effective": "2028-02-29T01:00:00+01:00", "assignment": "2024-03-04T14:49:30+01:00", "program": 94, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 3, "manager": 65558, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999904895", "ethics_committee": null, "edudract_number": null, "persons": [ "8065-54235-12", "8065-65558-10", "8065-99971-12", "8065-126174-12", "8065-134561-12" ] }, { "id": 7915, "title": { "de": "Ein atypischer Zugang zur Blutzuckerregulation - Die Rolle des atypischen Chemokinrezeptors ACKR4 in der diabetischen Stoffwechsellage", "en": "The atypical way of blood glucose regulation – investigation into the role of atypical chemokine receptor ACKR4 in metabolic homeostasis" }, "short": "ACKR4 und Hyperglykämie", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-10-01T02:00:00+02:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2027-04-30T02:00:00+02:00", "assignment": "2023-12-06T14:49:56+01:00", "program": null, "subprogram": null, "organization": 14084, "category": 10, "type": 10, "partner_function": 4, "manager": 86588, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7915-86124-12", "7915-86588-10", "7915-107070-12", "7915-104723-12" ] }, { "id": 8279, "title": { "de": "Bekämpfung von Gewaltverbrechen gegen Frauen und Mädchen in Georgien", "en": "Countering violent crime against women and girls in Georgia (formerly known as “Building strength and commitment to counter violent crime: From academic interventions to societal transformations”)" }, "short": "COVIOCRIM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2027-03-01T01:00:00+01:00", "end_effective": "2027-02-28T01:00:00+01:00", "assignment": "2024-07-01T14:21:18+02:00", "program": 200, "subprogram": null, "organization": 14019, "category": 10, "type": 10, "partner_function": 2, "manager": 115441, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8279-115441-10" ] }, { "id": 8054, "title": { "de": "Ernährungsgewohnheiten von Patient*innen mit \r\nchronisch-entzündlichen Darmerkrankungen \r\nin Österreich und Deutschland", "en": "Diet and Nutrition among patients with inflammatory bowel disease in Austria and Germany" }, "short": "Nutrition IBD Study", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2024-10-01T02:00:00+02:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-02-21T10:50:23+01:00", "program": null, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 3, "manager": 53167, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 203 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8054-74515-12", "8054-53167-10", "8054-53167-12" ] }, { "id": 8079, "title": { "de": "Wirkmechanismus von Mikroplastik in entzündlichen Darmerkrankungen", "en": "Action of microplastic in inflammatory bowel diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2030-03-01T01:00:00+01:00", "end_effective": "2030-03-01T01:00:00+01:00", "assignment": "2024-03-11T14:44:13+01:00", "program": null, "subprogram": null, "organization": 17230, "category": 10, "type": 10, "partner_function": 4, "manager": 87298, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8079-87298-10" ] }, { "id": 8068, "title": { "de": "MICU1 als zentrale Schaltstelle für Signalweiterleitung und Metabolismus durch morphologische Anpassung der Cristae Junction", "en": "MICU1 is a central switching point for signal transmission and metabolism through morphological adaptation of the cristae junction" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2024-12-01T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-03-05T16:07:14+01:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 90394, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8068-90394-10" ] }, { "id": 7711, "title": { "de": "Der Zusammenhang von Herzmechanik und kardialem Remodeling", "en": "Linking cardiac biomechanics to reverse remodeling" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-07-01T02:00:00+02:00", "begin_effective": 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