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GET /v1/research/project/?format=api&offset=240&ordering=-begin_effective
{ "count": 2244, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=260&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=220&ordering=-begin_effective", "results": [ { "id": 8235, "title": { "de": "LYMPHO-CHECK: Lymphoma Mausmodelle und funktionelle Genomik", "en": "LYMPHO-CHECK: Lympha mouse models and functional genomics" }, "short": "LYMPHO-CHECK", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-06-03T02:00:00+02:00", "end_planned": "2029-12-31T01:00:00+01:00", "end_effective": "2029-06-02T02:00:00+02:00", "assignment": "2024-06-03T14:29:07+02:00", "program": 113, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 2, "manager": 89979, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 30", "ethics_committee": null, "edudract_number": null, "persons": [ "8235-89979-10" ] }, { "id": 8233, "title": { "de": "Die Nr4a1/P53 Achse in der Immun Evasion von Lymphomen", "en": "NR4A1-P53 AXIS IN THE IMMUNE EVASION OF AGGRESSIVE LYMPHOMAS" }, "short": "LYMPHO-CHECK", "url": null, "abstract": { "de": "Aggressive Lymphome gehören zu den häufigsten Arten von Lymphdrüsenkrebs und stellen eine große Herausforderung für die Behandlung dar. Checkpoint-Blockade-Therapien (CBTs) haben sich als vielversprechender Weg erwiesen, um der Umgehung der Anti-Tumor-Immunantwort durch den Tumor entgegenzuwirken. Trotz ihres Potenzials sind CBTs mit erheblichen Kosten verbunden und basieren häufig auf Trial-and-Error-Ansätzen. Zudem sprechen nur ein kleiner Prozentsatz der Lymphom-Patienten (10-20%) auf CBT an, teilweise aufgrund eines Mangels an Verständnis darüber, wie Immun-Checkpoints während der Entwicklung von Lymphomen reguliert werden, sowie aufgrund des Fehlens prädiktiver Biomarker. Unsere jüngsten Forschungsergebnisse haben wichtige Faktoren aufgedeckt, die zu schlechten Ergebnissen bei Patienten mit diffusen großzelligen B-Zell-Lymphomen (DLBCL) beitragen. Wir beobachteten signifikante Abnahmen der NR4A1- und p53-Spiegel, die wichtige Regulatoren der Genexpression sind, vergesellschaftet mit erhöhten Checkpoint-Komponenten-Gehalt. Bei Mäusen führte die Deletion von NR4A1 zu reduzierten p53-Spiegeln, beschleunigter Lymphomentwicklung und erhöhter Expression von immuninhibitorischen Checkpoint-Komponenten. Diese Ergebnisse deuten auf eine funktionelle Beziehung zwischen NR4A1 und p53, die in der Immunantwort auf Tumore die Expression von Checkpoint-Komponenten in aggressiven Lymphomen reguliert.\r\nUnser vorgeschlagenes Forschungsprojekt zielt darauf ab, diese Herausforderungen durch die Entwicklung neuer Mausmodelle mit spezifischen Deletionen von NR4A1 und/oder p53 in B-Zellen anzugehen. Unter Verwendung fortschrittlicher molekularer und genomweiter Techniken werden wir umfassend untersuchen, wie Lymphome in diesen Modellen entstehen. Außerdem werden wir eine Methode zur wiederholten Gewebsflüssigkeitsentnahme adaptieren und damit wiederholte Messungen von Zytokinsignalen und zellulären Veränderungen in sich entwickelnden Tumoren durchführen, wodurch wertvolle Einblicke in das Lymphom-Mikromilieu gewonnen werden. Mit Hilfe dieser Modelle hoffen wir, neue Checkpoint-Blockade-Therapien für aggressive Lymphom entwickeln und auf den Status von NR4A1 und p53 abstimmen zu können. Zur Validierung unserer Ergebnisse werden wir eine große Kohorte von Lymphomproben von Patienten analysieren und mit öffentlich verfügbaren Datensätzen vergleichen. Letztendlich ist es unser Ziel, die klinische Relevanz der NR4A1-p53-Checkpoint-Achse zu bewerten und neue Biomarker zu identifizieren, die bei aggressiven Lymphomen als Entscheidungshilfe für die Behandlung mit Checkpoint-Inhibitoren dienen können. Durch unsere Forschung wollen wir die Ergebnisse für Patienten mit aggressiven Lymphomen verbessern, indem wir wirksamere und personalisierte Behandlungsstrategien entwickeln.\r\n", "en": "Aggressive lymphomas are among the most common types of lymphoid cancers and consist of Burkitt’s lymphoma, diffuse large B cell lymphoma (DLBCL), follicular lymphoma grade 3. While checkpoint blockade therapies (CBTs) have emerged as a promising avenue to counteract tumor evasion, this treatment form comes with substantial cost burdens and often rely on trial-and-error approaches. Importantly, only a small percentage of lymphoma patients (10-20%) respond favorably to CBT, partly due to the limited understanding of the regulation of immune checkpoints during lymphoma development and the absence of predictive biomarkers. Our recent investigations have shed light on key factors contributing to poor outcomes in patients with DLBCL. We observed significant decreases in the levels of NR4A1 and p53, which are important regulators of gene expression and known tumor suppressors, alongside high expression of checkpoint components. In mice, depletion of NR4A1 led to reduced p53 levels, accelerated lymphoma development, and increased expression of immune-inhibitory checkpoint components, particularly in animals with intact immune systems. These and other findings suggest a functional relationship involving NR4A1, p53, and the orchestrating immune evasive mechanisms in aggressive lymphomas.\r\nOur proposed research project aims to address this axis by developing new mouse models with specific and inducible deletion of NR4A1 and/or p53 in B cells. Using advanced molecular and genomic techniques, we will comprehensively study lymphoma development in these models. We will also implement a tissue fluid sampling method to repeatedly measure cytokine signals and cellular changes within evolving tumors, providing valuable insights into the lymphoma microenvironment. By leveraging these models, we aim to tailor CBTs based on the status of NR4A1 and p53. To clinically validate our findings, we will analyze a large cohort of lymphoma samples from GRAZ lymphoma cohort and compare them with publicly available datasets. Ultimately, our goal is to functionally establish the clinical relevance of the NR4A1-p53-checkpoint axis and identify new biomarkers that can help guide treatment decisions involving checkpoint inhibitors for aggressive lymphomas. Through our research, we are poised to improve outcomes for patients with aggressive lymphomas by developing more effective and personalized treatment strategies.\r\n" }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-06-03T02:00:00+02:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2029-06-02T02:00:00+02:00", "assignment": "2024-06-03T13:00:14+02:00", "program": 113, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 3, "manager": 59183, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 30", "ethics_committee": null, "edudract_number": null, "persons": [ "8233-100134-12", "8233-59183-10", "8233-79614-12", "8233-82501-12", "8233-85928-12", "8233-111069-12", "8233-102513-12", "8233-132158-12", "8233-122350-12" ] }, { "id": 8236, "title": { "de": "LYMPHO-CHECK: Bioinformatik und Data-Mining in der Lymphomforschung\r\n ", "en": "LYMPHO-CHECK: Bioinformatics and Data Mining in Lymphoma Research" }, "short": "LYMPHO-CHECK", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-06-03T02:00:00+02:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2029-06-02T02:00:00+02:00", "assignment": "2024-06-03T14:29:51+02:00", "program": 113, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 2, "manager": 94195, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 30", "ethics_committee": null, "edudract_number": null, "persons": [ "8236-94195-10" ] }, { "id": 8393, "title": { "de": "Spezies-Diversität von Pilzen in verarbeiteten Grundnahrungsmitteln aus Subsistenzwirtschaftsgemeinschaften im ländlichen Namibia", "en": "Fungal diversity of processed staple cereals from rural subsistence farming communities in Namibia" }, "short": "FUNGINAM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-08-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2026-07-31T02:00:00+02:00", "end_effective": "2026-05-31T02:00:00+02:00", "assignment": "2024-09-19T13:21:41+02:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 112729, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8393-112729-10" ] }, { "id": 8142, "title": { "de": "TARgetinG disease pErsisTence and progression of\r\nMyeloProliferative Neoplasms", "en": "TARgetinG disease pErsisTence and progression of\r\nMyeloProliferative Neoplasms" }, "short": "TARGET MPN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2028-01-01T01:00:00+01:00", "end_effective": "2028-07-10T02:00:00+02:00", "assignment": "2024-04-18T12:35:12+02:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 107132, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I06944", "ethics_committee": null, "edudract_number": null, "persons": [ "8142-107132-10", "8142-134381-12", "8142-101484-12", "8142-126596-12" ] }, { "id": 8562, "title": { "de": "Pilotprojekt Telemedizin in der klinisch-forensischen Untersuchung", "en": "-" }, "short": "Telemedizin_klin-foren_Untersuchungen", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-07-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-12-12T14:49:41+01:00", "program": null, "subprogram": null, "organization": 14019, "category": 10, "type": 10, "partner_function": 4, "manager": 115441, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8562-115441-10" ] }, { "id": 8465, "title": { "de": "Ansätze zur Frühdiagnose auf Basis von Flüssigbiopsiemarkern", "en": "Approaches for early diagnosis based on liquid biopsy markers" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-06-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-10-30T17:30:19+01:00", "program": 94, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 1, "manager": 66435, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8465-66435-10" ] }, { "id": 8414, "title": { "de": "Entschlüsselung der Auswirkungen von NR4A1 auf die Tumormikroumgebung und Interaktionen auf Immun- und Lymphomzellen in aggressiven Lymphomen", "en": "Deciphering the impact of NR4A1 on the Tumor Microenvironment and Interaction of Immune and Lymphoma Cells in aggressive Lymphoma" }, "short": null, "url": null, "abstract": { "de": "NR4A1 ist ein nukleärer Rezeptor, der eine Schlüsselrolle bei der Regulation der Tumormikroumgebung (TME) und der Interaktion zwischen Immun- und Lymphomzellen in aggressiven Lymphomen spielt. Trotz wachsender Erkenntnisse über seine Funktion bleibt unklar, wie NR4A1 die Immunantwort moduliert und das Wachstum von Lymphomzellen beeinflusst. In dieser Studie untersuchen wir die Auswirkungen von NR4A1 auf Immunzellen, insbesondere auf T-Zellen und Makrophagen, sowie auf die zellulären und molekularen Mechanismen, die zur Tumorprogression beitragen. Mithilfe modernster Einzelzell-RNA-Sequenzierung und funktioneller Immunanalysen analysieren wir die NR4A1-vermittelten Signalwege in der TME. Unsere Ergebnisse könnten neue therapeutische Ansätze zur gezielten Beeinflussung von NR4A1 in der Immunmodulation und Lymphombehandlung ermöglichen.", "en": "NR4A1 is a nuclear receptor that plays a key role in regulating the tumor microenvironment (TME) and interactions between immune and lymphoma cells in aggressive lymphomas. Despite growing insights into its function, how NR4A1 modulates immune responses and influences lymphoma cell growth remains unclear. In this study, we investigate the impact of NR4A1 on immune cells, particularly T cells and macrophages, as well as the cellular and molecular mechanisms contributing to tumor progression. Using advanced single-cell RNA sequencing and functional immune analyses, we analyze NR4A1-mediated signaling pathways in the TME. Our findings may pave the way for novel therapeutic approaches targeting NR4A1 in immune modulation and lymphoma treatment." }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2027-04-01T02:00:00+02:00", "end_effective": "2027-05-31T02:00:00+02:00", "assignment": "2024-10-03T12:57:24+02:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 85928, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8414-85928-10" ] }, { "id": 8117, "title": { "de": "Bessere Blutgefäße: Elektrogesponnene Gerüste aus humanen Proteinen.", "en": "Building Better Blood Vessels: Human Protein Electrospun Scaffolds in Tissue Engineering." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-06-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2026-07-01T02:00:00+02:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-03-26T10:44:39+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 76930, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8117-76930-10" ] }, { "id": 7929, "title": { "de": "Nachhaltige gesunde Ernährung im Pflegeheim", "en": "Sustainable healthy nutrition in nursing homes " }, "short": "SUNRISE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-02-01T01:00:00+01:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2026-01-31T01:00:00+01:00", "end_effective": "2026-05-31T02:00:00+02:00", "assignment": "2023-12-14T15:30:17+01:00", "program": null, "subprogram": null, "organization": 14509, "category": 10, "type": 10, "partner_function": 4, "manager": 82963, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "TCS00142", "ethics_committee": null, "edudract_number": null, "persons": [ "7929-82963-10" ] }, { "id": 8381, "title": { "de": "Von der Entstehung einer Arrhythmie bis zur Progression: Aufdeckung der molekularen Mechanismen, die Herzrhythmusstörungen stabilisieren", "en": "From arrhythmia initiation to progression: uncovering the molecular mechanisms stabilizing cardiac arrhythmias using a computational-experimental approach" }, "short": "NWOVidi", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-06-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2026-08-14T02:00:00+02:00", "end_effective": "2026-08-14T02:00:00+02:00", "assignment": "2024-09-05T19:11:41+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 123850, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8381-123850-10" ] }, { "id": 7942, "title": { "de": "Alterungsforschung Hands-On", "en": "Aging Research Hands-On" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-06-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2026-05-31T02:00:00+02:00", "end_effective": "2027-05-31T02:00:00+02:00", "assignment": "2023-12-19T15:35:12+01:00", "program": 122, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 1, "manager": 85069, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "WKP 235-B", "ethics_committee": null, "edudract_number": null, "persons": [ "7942-85069-10" ] }, { "id": 8078, "title": { "de": "Isolierung und Charakterisierung verschiedener zytosolischer Lipidspeicher im Dünndarm", "en": "Isolation and characterization of different cytosolic lipid droplet stores in the small intestine" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-05-01T02:00:00+02:00", "begin_effective": "2024-05-06T02:00:00+02:00", "end_planned": "2024-11-30T01:00:00+01:00", "end_effective": "2024-12-05T01:00:00+01:00", "assignment": "2024-03-11T11:32:28+01:00", "program": 204, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 76131, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 15 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8078-76131-10" ] }, { "id": 8230, "title": { "de": "Untersuchung von anti EGF-R virus-ähnlicher Partikel", "en": "Testing of anti EGF-R virus-like particles (VLPs)" }, "short": "VLPs", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-06-01T02:00:00+02:00", "begin_effective": "2024-05-01T02:00:00+02:00", "end_planned": "2025-12-30T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-05-27T14:59:52+02:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 1, "manager": 50593, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8230-50593-10" ] }, { "id": 8062, "title": { "de": "Stärkung des schwächelnden Herzens", "en": "Energizing the failing heart" }, "short": "Ener-LIGHT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-02-01T01:00:00+01:00", "begin_effective": "2024-05-01T02:00:00+02:00", "end_planned": "2027-01-31T01:00:00+01:00", "end_effective": "2027-04-30T02:00:00+02:00", "assignment": "2024-03-04T08:37:32+01:00", "program": 112, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 3, "manager": 94512, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8062-94512-10", "8062-104482-12", "8062-126154-12", "8062-135812-12" ] }, { "id": 8719, "title": { "de": "Fetale Programmierung von Adipositas", "en": "Programming of neonatal adipose tissue by gestational diabetes" }, "short": "Prone Adiposity", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-05-01T02:00:00+02:00", "end_planned": "2027-09-01T02:00:00+02:00", "end_effective": "2027-11-01T01:00:00+01:00", "assignment": "2025-03-11T16:06:47+01:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": 50674, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 37199", "ethics_committee": null, "edudract_number": null, "persons": [ "8719-88993-12", "8719-50674-10", "8719-61680-12", "8719-135894-12", "8719-122576-12", "8719-124255-12", "8719-128675-12" ] }, { "id": 8217, "title": { "de": "Regulation von TRPV6 durch PIP2 im Membranparalipidom", "en": "Towards understanding the regulation of TRPV6 channels by sensing PIP2 in the functional paralipidome\r\n\r\nKurztitel: TRPV6 regulation by sensing PIP2 in the paralipidome" }, "short": "NA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-05-01T02:00:00+02:00", "begin_effective": "2024-05-01T02:00:00+02:00", "end_planned": "2027-04-30T02:00:00+02:00", "end_effective": "2027-04-30T02:00:00+02:00", "assignment": "2024-05-16T14:13:14+02:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 78591, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PAT9543223", "ethics_committee": null, "edudract_number": null, "persons": [ "8217-78591-10" ] }, { "id": 7983, "title": { "de": "Gewebe-infiltrierende Lymphozyten - Direkte Evaluierung der Rezeptoren", "en": "Tissue-infiltrating Lymphocytes - Direct Evaluation of Receptors" }, "short": "TIL-DER", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-01-19T11:58:34+01:00", "program": 117, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 3, "manager": 98567, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "FO999909640", "ethics_committee": null, "edudract_number": null, "persons": [ "7983-98567-10" ] }, { "id": 7710, "title": { "de": "Metabolomics bei PH: Erkennung und Risikovorhersage", "en": "Metabolomics in PH: detection, risk prediction, monitoring" }, "short": "GRAPH-M", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2027-12-31T01:00:00+01:00", "end_effective": "2028-03-31T02:00:00+02:00", "assignment": "2023-08-08T13:40:35+02:00", "program": 108, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 54345, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI 1153", "ethics_committee": null, "edudract_number": null, "persons": [ "7710-91409-12", "7710-73404-12", "7710-115981-12", "7710-54345-10" ] }, { "id": 7984, "title": { "de": "Gewebe-infiltrierende Lymphozyten - Direkte Evaluierung der Rezeptoren ", "en": "Tissue-infiltrating Lymphocytes - Direct Evaluation of Receptors " }, "short": "TIL-DER", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-01-19T12:01:27+01:00", "program": 117, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 97234, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7984-97234-10" ] } ] }