Project List

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    "results": [
        {
            "id": 2248,
            "title": {
                "de": "Interaktionen eosinophiler Granulozyten mit dem Endothel und die Hierarchie von eosinophilen Lockstoffen",
                "en": "Interactions of Eosinophils with the Endothelium and the Hierarchy of Eosinophil Chemoattractants"
            },
            "short": "Interactions of Eosinophils",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-08-01T02:00:00+02:00",
            "begin_effective": "2010-08-01T02:00:00+02:00",
            "end_planned": "2011-04-30T02:00:00+02:00",
            "end_effective": "2011-04-30T02:00:00+02:00",
            "assignment": "2010-07-09T15:47:14+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14022,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 57573,
            "contact": 57573,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                15
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2248-57573-10"
            ]
        },
        {
            "id": 2341,
            "title": {
                "de": "Einzelzellanalyse in der forensischen Medizin",
                "en": "Single cell analysis in forensic medicine"
            },
            "short": "Single cell analysis",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-05-01T02:00:00+02:00",
            "begin_effective": "2010-12-01T01:00:00+01:00",
            "end_planned": "2011-04-30T02:00:00+02:00",
            "end_effective": "2011-12-31T01:00:00+01:00",
            "assignment": "2010-11-17T11:21:30+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14017,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 54171,
            "contact": 54171,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2341-54171-10"
            ]
        },
        {
            "id": 2375,
            "title": {
                "de": "Grazer Laser Studie GLAS",
                "en": "Grazer Laser Study GLAS"
            },
            "short": "GLAS",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-01-01T01:00:00+01:00",
            "begin_effective": "2010-01-01T01:00:00+01:00",
            "end_planned": "2011-04-30T02:00:00+02:00",
            "end_effective": "2011-07-31T02:00:00+02:00",
            "assignment": "2011-01-10T11:10:16+01:00",
            "program": 75,
            "subprogram": null,
            "organization": 14043,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2151,
            "title": {
                "de": "Entwicklung eines praktikablen Werkzeugs für die Bewertung und Implementierung evidenzbasierter Leitlinien in Kooperation mit den Krankenhäusern in der Steiermark",
                "en": "Entwicklung eines praktikablen Werkzeugs für die Bewertung und Implementierung evidenzbasierter Leitlinien in Kooperation mit den Krankenhäusern in der Steiermark"
            },
            "short": "EVIDENZBASIERTE LEITLINIEN",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2009-05-01T02:00:00+02:00",
            "begin_effective": "2009-05-01T02:00:00+02:00",
            "end_planned": "2011-04-30T02:00:00+02:00",
            "end_effective": "2011-04-30T02:00:00+02:00",
            "assignment": "2010-03-04T12:31:15+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14026,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51098,
            "contact": 51098,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2151-51098-10"
            ]
        },
        {
            "id": 2349,
            "title": {
                "de": "Entwicklung eines integrierten Disease Management Programmes für Typ 2 Diabetiker und die Evaluierung in einer randomisierten, kontrollierten Studie - Albert Renold Travel Fellowship",
                "en": "Development of an Integrated Diabetes Care Management System and its evaluation in a clustered randomized, controlled trial - Albert Renold Travel Fellowship"
            },
            "short": "INTEGRATED DIABETES CARE MANAGEMENT",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-02-01T01:00:00+01:00",
            "begin_effective": "2010-10-01T02:00:00+02:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2011-05-31T02:00:00+02:00",
            "assignment": "2010-12-02T12:15:53+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14080,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50838,
            "contact": 50838,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                431
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2349-50838-10"
            ]
        },
        {
            "id": 2198,
            "title": {
                "de": "Kommunikation als Screeninginstrument",
                "en": "Kommunikation als Screeninginstrument"
            },
            "short": "KOMMUNIK_SCREENING",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2009-10-01T02:00:00+02:00",
            "begin_effective": "2010-04-01T02:00:00+02:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2012-03-31T02:00:00+02:00",
            "assignment": "2010-05-07T16:16:27+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14043,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 54332,
            "contact": 54332,
            "status": 2,
            "research": 5,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                70
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2198-54332-10"
            ]
        },
        {
            "id": 2418,
            "title": {
                "de": "Uveales Melanom: Bio-psycho-soziale Aspekte",
                "en": "Uveal melanoma: Bio-psyco-social aspects "
            },
            "short": "UVEAL MELANOMA_BIO_PSYCHO_SOCIAL_ASPECTS",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-06-01T02:00:00+02:00",
            "begin_effective": "2011-02-01T01:00:00+01:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2012-01-31T01:00:00+01:00",
            "assignment": "2011-02-17T11:06:13+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14043,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 61522,
            "contact": 61522,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                938
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2418-61522-10"
            ]
        },
        {
            "id": 2451,
            "title": {
                "de": "Ein US28/GNA Fusionsprotein zur Induktion der Apoptose beim Melanom",
                "en": "A US28/GNA Fusion Protein to Induce Apoptosis in Melanoma "
            },
            "short": "US28/GNA and Melanoma",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2011-03-01T01:00:00+01:00",
            "begin_effective": "2011-04-01T02:00:00+02:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2011-12-30T01:00:00+01:00",
            "assignment": "2011-03-23T11:47:48+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14047,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 53662,
            "contact": 53662,
            "status": 2,
            "research": 3,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2451-53662-10"
            ]
        },
        {
            "id": 1779,
            "title": {
                "de": "Early signs of rett syndrome",
                "en": "Early signs of rett syndrome"
            },
            "short": "EARLY SIGNS RETT SYNDROME",
            "url": null,
            "abstract": {
                "de": "Rett Syndrom, eine schwerwiegende neurologische Erkrankung, durch de novo-Mutationen des MECP2 Gens verursacht, hat einen vierphasigen Verlauf: Nach einem mehr oder weiniger unauffälligen ersten Lebensjahr (Phase 1) kommt es zur Regression (Phase 2), in der erworbene Fähigkeiten wie Sprache und motorische Funktionen wieder verloren gehen. In dieser Zeit treten auch die für das Rett-Syndrom charakteristischen Handstereotypien auf. Mit Phase 3 tritt eine relative Stabilisierung des Entwicklungsstandes ein; Phase 4 ist gekennzeichnet von erneuten motorischen und kognitiven Beeinträchtigungen. Da eine Diagnose meist erst im Vorschul- oder Schulalter erfolgt, gibt es wenig systematisches Wissen über die Prä-Regressionsphase. \r\nZiel des eingereichten Projekts ist die Erstellung spezifischer Entwicklungsprofile dieser ersten Phase und zwar in Abhängigkeit von Locus und Typ (missense/nonsense) der Mutation. Unsere detaillierten Analysen der Frühzeichen sowie der Genotyp-Phänotyp Beziehungen und des prä-diagnostischen Verlaufs basieren auch auf Audio- und Videoaufnahmen, die uns von betroffenen Patienten und deren Familien weltweit zur Verfügung gestellt werden. Diese internationalen Kooperationen stellen uns vor das Problem technisch unterschiedlicher Aufnahmesysteme. Ein Video-Konverter würde unsere Arbeit erheblich erleichtern und den Datenverlust minimieren. Damit könnten wir letzlich unserem längerfristigen Ziel der besseren Versorgung betroffener Mädchen und ihrer Familien durch das verlässliche Identifizieren von Frühzeichen einen Schritt näher kommen.",
                "en": "Rett Syndrom, eine schwerwiegende neurologische Erkrankung, durch de novo-Mutationen des MECP2 Gens verursacht, hat einen vierphasigen Verlauf: Nach einem mehr oder weiniger unauffälligen ersten Lebensjahr (Phase 1) kommt es zur Regression (Phase 2), in der erworbene Fähigkeiten wie Sprache und motorische Funktionen wieder verloren gehen. In dieser Zeit treten auch die für das Rett-Syndrom charakteristischen Handstereotypien auf. Mit Phase 3 tritt eine relative Stabilisierung des Entwicklungsstandes ein; Phase 4 ist gekennzeichnet von erneuten motorischen und kognitiven Beeinträchtigungen. Da eine Diagnose meist erst im Vorschul- oder Schulalter erfolgt, gibt es wenig systematisches Wissen über die Prä-Regressionsphase. \r\nZiel des eingereichten Projekts ist die Erstellung spezifischer Entwicklungsprofile dieser ersten Phase und zwar in Abhängigkeit von Locus und Typ (missense/nonsense) der Mutation. Unsere detaillierten Analysen der Frühzeichen sowie der Genotyp-Phänotyp Beziehungen und des prä-diagnostischen Verlaufs basieren auch auf Audio- und Videoaufnahmen, die uns von betroffenen Patienten und deren Familien weltweit zur Verfügung gestellt werden. Diese internationalen Kooperationen stellen uns vor das Problem technisch unterschiedlicher Aufnahmesysteme. Ein Video-Konverter würde unsere Arbeit erheblich erleichtern und den Datenverlust minimieren. Damit könnten wir letzlich unserem längerfristigen Ziel der besseren Versorgung betroffener Mädchen und ihrer Familien durch das verlässliche Identifizieren von Frühzeichen einen Schritt näher kommen."
            },
            "begin_planned": "2009-06-01T02:00:00+02:00",
            "begin_effective": "2009-06-01T02:00:00+02:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2011-05-31T02:00:00+02:00",
            "assignment": "2009-04-09T16:53:18+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14010,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 58883,
            "contact": 58883,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                896
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "1779-58883-10"
            ]
        },
        {
            "id": 1510,
            "title": {
                "de": "EuroSTEC: Soft tissue engineering for congenital birth defects in children: from \"biomatrix - cell interaction - model system\" to clinical trials",
                "en": "EuroSTEC: Soft tissue engineering for congenital birth defects in children: from \"biomatrix - cell interaction - model system\" to clinical trials"
            },
            "short": "IMPPACT",
            "url": null,
            "abstract": {
                "de": "IMPPACT will develop an intervention planning and monitoring application for Radiofrequency Ablation (RFA) of malignant liver tumours. RFA is a minimally invasive form to treat cancer without open surgery, by placing a needle inside the malignancy and destroying it through intensive heating. Though the advantages of this approach ale obvious, the intervention is currently hard to plan, almost impossible to monitor or assess, and therefore is not the first choice for treatment. IMPPACT will develop a physiological model of the liver and simulate the intervention's result, accounting for patient specific physiological factors. Gaps in the understanding of particular aspects of the RFA treatment will be closed by multi-scale studies on cells and animals. New findings will be evaluated microscopically and transformed into macroscopic equations. The long-established bio-heat equation will be extended to incorporate multiple scales. Validation will be performed at multiple levels. Images from ongoing patient treatment will be used to cross check validity for human physiology. Final validation will be performed at macroscopic level through visual comparison of simulation and treatment results gathered in animal studies and during patient treatment. This extensive validation together with a user-centered software design approach will guarantee suitability of the solution for clinical practice. The consortium consists of two Hospitals, three Universities, one Research Institute and one industrial SME. The final project deliverables will be the patient specific intervention planning system and an augmented reality training simulator for the RFA intervention.",
                "en": "IMPPACT will develop an intervention planning and monitoring application for Radiofrequency Ablation (RFA) of malignant liver tumours. RFA is a minimally invasive form to treat cancer without open surgery, by placing a needle inside the malignancy and destroying it through intensive heating. Though the advantages of this approach ale obvious, the intervention is currently hard to plan, almost impossible to monitor or assess, and therefore is not the first choice for treatment. IMPPACT will develop a physiological model of the liver and simulate the intervention's result, accounting for patient specific physiological factors. Gaps in the understanding of particular aspects of the RFA treatment will be closed by multi-scale studies on cells and animals. New findings will be evaluated microscopically and transformed into macroscopic equations. The long-established bio-heat equation will be extended to incorporate multiple scales. Validation will be performed at multiple levels. Images from ongoing patient treatment will be used to cross check validity for human physiology. Final validation will be performed at macroscopic level through visual comparison of simulation and treatment results gathered in animal studies and during patient treatment. This extensive validation together with a user-centered software design approach will guarantee suitability of the solution for clinical practice. The consortium consists of two Hospitals, three Universities, one Research Institute and one industrial SME. The final project deliverables will be the patient specific intervention planning system and an augmented reality training simulator for the RFA intervention."
            },
            "begin_planned": "2008-06-01T02:00:00+02:00",
            "begin_effective": "2008-09-01T02:00:00+02:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2011-12-31T01:00:00+01:00",
            "assignment": "2008-04-09T17:00:52+02:00",
            "program": 24,
            "subprogram": null,
            "organization": 14073,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 50874,
            "contact": 50874,
            "status": 2,
            "research": 3,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                10
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "1510-50874-10",
                "1510-62118-12",
                "1510-51955-12",
                "1510-51983-12"
            ]
        },
        {
            "id": 2398,
            "title": {
                "de": "SIMNET STYRIA 2009/2010",
                "en": "SIMNET STYRIA 2009/2010"
            },
            "short": "SIMNET",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2009-05-18T02:00:00+02:00",
            "begin_effective": "2009-05-18T02:00:00+02:00",
            "end_planned": "2011-05-31T02:00:00+02:00",
            "end_effective": "2011-05-31T02:00:00+02:00",
            "assignment": "2011-02-07T14:48:55+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14011,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 50966,
            "contact": 50966,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2398-50966-10"
            ]
        },
        {
            "id": 1822,
            "title": {
                "de": "Mechanisms of restoration of ß-cell function in relation to adipoinsular and enteroinsular axes after gastric bypass surgery in severly obese patients with type 2 diabetes - double-centre, prospective, controlled, longitudinal open study - short: Restoration of ß-cell function after gastric bypass",
                "en": "Mechanisms of restoration of ß-cell function in relation to adipoinsular and enteroinsular axes after gastric bypass surgery in severly obese patients with type 2 diabetes - double-centre, prospective, controlled, longitudinal open study - short: Restoration of ß-cell function after gastric bypass"
            },
            "short": "Restoration of ß-cell function",
            "url": null,
            "abstract": {
                "de": "The presented project aims to: \r\n1) compare changes in â-cell function following gastric bypass in patients with short- and long-term history of type 2 diabetes (T2DM), \r\n2) evaluate the â-cell insulin response to oral and intravenous glucose load early and late after gastric bypass surgery,\r\n3) relate the early and long-term changes in â-cell function after gastric bypass to changes in parameters of adipoinsular and enteroinsular axes in patients with and without T2DM and \r\n4) compare the changes of adipoinsular and enteroinsular axes after weight loss achieved after gastric bypass with BMI-matched controls without bariatric surgery.",
                "en": "The presented project aims to: \r\n1) compare changes in â-cell function following gastric bypass in patients with short- and long-term history of type 2 diabetes (T2DM), \r\n2) evaluate the â-cell insulin response to oral and intravenous glucose load early and late after gastric bypass surgery,\r\n3) relate the early and long-term changes in â-cell function after gastric bypass to changes in parameters of adipoinsular and enteroinsular axes in patients with and without T2DM and \r\n4) compare the changes of adipoinsular and enteroinsular axes after weight loss achieved after gastric bypass with BMI-matched controls without bariatric surgery."
            },
            "begin_planned": "2009-07-01T02:00:00+02:00",
            "begin_effective": "2009-07-01T02:00:00+02:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2012-04-30T02:00:00+02:00",
            "assignment": "2009-05-18T17:08:39+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14080,
            "category": 10,
            "type": 10,
            "partner_function": 2,
            "manager": 51831,
            "contact": 51831,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                431
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "1822-51831-10"
            ]
        },
        {
            "id": 2256,
            "title": {
                "de": "Stammbaumanalysen bei PatientInnen mit Therapie-assoziierten myeloischen Neoplasien",
                "en": "Stammbaumanalysen bei PatientInnen mit Therapie-assoziierten myeloischen Neoplasien"
            },
            "short": "myeloische Neoplasien",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-01-01T01:00:00+01:00",
            "begin_effective": "2010-01-01T01:00:00+01:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2014-04-30T02:00:00+02:00",
            "assignment": "2010-07-28T12:50:24+02:00",
            "program": null,
            "subprogram": "Land Steiermark Abteilung 3 (Forschung); Projektsumme über 5.000,- €",
            "organization": 14082,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51857,
            "contact": 51857,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2256-77615-12",
                "2256-77770-12",
                "2256-51857-10",
                "2256-50116-12"
            ]
        },
        {
            "id": 2165,
            "title": {
                "de": "\"Blauer LASER\" in der Akupunktur-Weltweit erste wissenschaftliche Untersuchungen am interuniversitären TCM Forschungszentrum Graz",
                "en": "\"Blauer LASER\" in der Akupunktur-Weltweit erste wissenschaftliche Untersuchungen am interuniversitären TCM Forschungszentrum Graz"
            },
            "short": "Blauer LASER",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-01-01T01:00:00+01:00",
            "begin_effective": "2010-04-01T02:00:00+02:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2011-09-30T02:00:00+02:00",
            "assignment": "2010-03-29T18:06:01+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14044,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                457
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2325,
            "title": {
                "de": "Bedeutung von MikroRNAs im Wnt Signalweg beim Gallengangskarzinom",
                "en": "Role of microRNAs of the wnt pathway in biliary tract cancer"
            },
            "short": "MICRORNAS WNT PATHWAY ",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-07-01T02:00:00+02:00",
            "begin_effective": "2010-11-01T01:00:00+01:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2012-06-30T02:00:00+02:00",
            "assignment": "2010-10-11T11:00:11+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14085,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": null,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": []
        },
        {
            "id": 2214,
            "title": {
                "de": "Identifizierung und funktionelle Charakterisierung von nukleären Rezeptoren als Tumorsuppressorgene bei aggressiven non-Hodgkin-Lymphomen",
                "en": "Identifizierung und funktionelle Charakterisierung von nukleären Rezeptoren als Tumorsuppressorgene bei aggressiven non-Hodgkin-Lymphomen"
            },
            "short": "Tumorsuppressorgene_non-Hodgkin-Lymphom",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-01-01T01:00:00+01:00",
            "begin_effective": "2010-01-01T01:00:00+01:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2015-04-30T02:00:00+02:00",
            "assignment": "2010-05-26T11:09:01+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14082,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 51930,
            "contact": 51930,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                135
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2214-65239-12",
                "2214-51930-10"
            ]
        },
        {
            "id": 1865,
            "title": {
                "de": "Prognostic evaluation of circulating methylated DNA using HRM assay in colorectal cancer patients",
                "en": "Prognostic evaluation of circulating methylated DNA using HRM assay in colorectal cancer patients"
            },
            "short": "PROGNOSTIC EVALUATION_COLORECTAL_CANCER",
            "url": null,
            "abstract": {
                "de": "Beim kolorektalen Karzinom handelt es sich um einen der häufigsten malignen Tumore des Menschen. Eine operative Entfernung der Tumore in den Stadien I und II ist sehr effektiv, allerdings kommt es in 20-30% der Fälle zu Rezidiven. Daher ist es sehr wichtig, jene Patienten zu identifizieren, welche mit hoher Wahrscheinlichkeit ein Rezidiv entwickeln, und somit von einer Chemotherapie profitieren würden. Veränderte DNA Methylierung in Tumoren ist ein Kennzeichen von Krebs und wurde in kolorektalen Tumoren bereits umfassend untersucht. Eine veränderte Promotor-Methylierung kann auch in frei zirkulierenden Nukleinsäuren aus Serum detektiert werden, und stellt ein neue nicht-invasive Methode dar, um Hochrisikopatienten zu identifizieren.\r\nZiel dieses Projektes ist die Etablierung der High-Resolution Melting Real-Time PCR als prognostisches Werkzeug zur Risikoabschätzung von Wiederauftreten kolorektaler Tumoren bei Stadium II Patienten.",
                "en": "Beim kolorektalen Karzinom handelt es sich um einen der häufigsten malignen Tumore des Menschen. Eine operative Entfernung der Tumore in den Stadien I und II ist sehr effektiv, allerdings kommt es in 20-30% der Fälle zu Rezidiven. Daher ist es sehr wichtig, jene Patienten zu identifizieren, welche mit hoher Wahrscheinlichkeit ein Rezidiv entwickeln, und somit von einer Chemotherapie profitieren würden. Veränderte DNA Methylierung in Tumoren ist ein Kennzeichen von Krebs und wurde in kolorektalen Tumoren bereits umfassend untersucht. Eine veränderte Promotor-Methylierung kann auch in frei zirkulierenden Nukleinsäuren aus Serum detektiert werden, und stellt ein neue nicht-invasive Methode dar, um Hochrisikopatienten zu identifizieren.\r\nZiel dieses Projektes ist die Etablierung der High-Resolution Melting Real-Time PCR als prognostisches Werkzeug zur Risikoabschätzung von Wiederauftreten kolorektaler Tumoren bei Stadium II Patienten."
            },
            "begin_planned": "2009-07-01T02:00:00+02:00",
            "begin_effective": "2009-07-01T02:00:00+02:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2012-06-30T02:00:00+02:00",
            "assignment": "2009-07-09T15:14:13+02:00",
            "program": 79,
            "subprogram": null,
            "organization": 14085,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 50899,
            "contact": 50899,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                12
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "1865-50899-10"
            ]
        },
        {
            "id": 2170,
            "title": {
                "de": "APA als diagnostischer Parameter für eine Hypophysenunterfunktion nach einem Schädel-Hirn-Trauma im Kindes- und Adolescentenalter.",
                "en": "APA as diagnostic tool for hypopituitarism after traumatic brain injury in children and adolescents."
            },
            "short": "APA und Hypophysenunterfunktion",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2010-06-30T02:00:00+02:00",
            "begin_effective": "2010-06-30T02:00:00+02:00",
            "end_planned": "2011-06-30T02:00:00+02:00",
            "end_effective": "2011-06-30T02:00:00+02:00",
            "assignment": "2010-04-08T16:34:10+02:00",
            "program": null,
            "subprogram": null,
            "organization": 14049,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 57571,
            "contact": 57571,
            "status": 2,
            "research": 4,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                457
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2170-57571-10"
            ]
        },
        {
            "id": 1955,
            "title": {
                "de": "Relationships between Sustainability and Well-being through European Lifelong Learning",
                "en": "Relationships between Sustainability and Well-being through European Lifelong Learning"
            },
            "short": "SUSTAINABILITY_LIFELONG_LEARNING",
            "url": null,
            "abstract": {
                "de": null,
                "en": null
            },
            "begin_planned": "2009-08-01T02:00:00+02:00",
            "begin_effective": "2009-08-01T02:00:00+02:00",
            "end_planned": "2011-07-31T02:00:00+02:00",
            "end_effective": "2011-07-31T02:00:00+02:00",
            "assignment": "2009-10-22T12:56:40+02:00",
            "program": 92,
            "subprogram": "GRUNDTVIG-Lernpartnerschaft - Programm Lebenslanges Lernen",
            "organization": 14024,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 53649,
            "contact": 53649,
            "status": 2,
            "research": 2,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                20
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "1955-53649-10"
            ]
        },
        {
            "id": 2091,
            "title": {
                "de": "Comparative in situ transcriptome analysis of the human cytotrophoblast and syncytiotrophoblast",
                "en": "Comparative in situ transcriptome analysis of the human cytotrophoblast and syncytiotrophoblast"
            },
            "short": "HUMAN CYTOTROPHOBLAST",
            "url": null,
            "abstract": {
                "de": null,
                "en": "Human placental villous trees are covered by a two-layered epithelium-like trophoblast layer, which consists of mononucleated cytotrophoblasts and an overlying multinucleated syncytiotrophoblast. Cell turnover in the trophoblast layer includes proliferation, differentiation and subsequent fusion of cytotrophoblasts with the syncytiotrophoblast. Thus, both layers represent stages of different degree of differentiation, ranging from very early differentiated (cytotrophoblast) to terminally differentiated stages (syncytiotrophoblast). Data on comparative whole transcriptome analyses between in vitro cultured mononucleated and multinucleated primary trophoblasts exist, but have their clear limitations. Withdrawal from the in vivo microenvironment as well as in vitro culture of primary cells alters gene expression profiles, which no longer resemble the in vivo situation. To overcome these limitations we intent to microdissect these two cell fractions directly from fixed, paraffin embedded placental tissue. Total RNAs from microdissected cytotrophoblasts and syncytiotrophoblast will be subjected to microarray analysis with the aim to detect differentially expressed genes. The expectations in this project are to gain insight into the spatial expression of genes relevant for trophoblast differentiation. Furthermore, this project should deliver the basis for follow-up studies comparing placentas from healthy and pathologic pregnancies."
            },
            "begin_planned": "2010-02-01T01:00:00+01:00",
            "begin_effective": "2010-02-01T01:00:00+01:00",
            "end_planned": "2011-07-31T02:00:00+02:00",
            "end_effective": "2011-07-31T02:00:00+02:00",
            "assignment": "2010-02-09T11:47:12+01:00",
            "program": null,
            "subprogram": null,
            "organization": 14017,
            "category": 10,
            "type": 10,
            "partner_function": 4,
            "manager": 53232,
            "contact": null,
            "status": 2,
            "research": 1,
            "grant": 10,
            "event": null,
            "study": null,
            "language": null,
            "funders": [
                894
            ],
            "funder_projectcode": null,
            "ethics_committee": null,
            "edudract_number": null,
            "persons": [
                "2091-53232-10"
            ]
        }
    ]
}