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GET /v1/research/project/?format=api&offset=2080&ordering=begin_effective
https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=2100&ordering=begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=2060&ordering=begin_effective", "results": [ { "id": 8537, "title": { "de": "AlveOlism: Wie Fettstoffwechsel Lungenregeneration fördert", "en": "AlveOlism: How Lipid CatabOlism fuels AlveOlar Regeneration" }, "short": "AlveOlism", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2028-03-31T02:00:00+02:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-12-03T09:54:10+01:00", "program": 72, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 57409, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PAT9976323", "ethics_committee": null, "edudract_number": null, "persons": [ "8537-57409-10", "8537-112150-12" ] }, { "id": 8412, "title": { "de": "Immunologische Evaluierung des pre-Sjögren Syndromes", "en": "Pre-Sjögren Syndrome Targeted Immunology \r\nEvaluation – The preSStige study" }, "short": "preSStige", "url": null, "abstract": { "de": "Die Sjögren Erkrankung (auch primäres Sjögren-Syndrom genannt) ist eine Autoimmunerkrankung, bei der das körpereigene Immunsystem die Speichel- und Tränendrüsen angreift und zerstört. Seltener können auch lebenswichtige Organe befallen sein. Die Erkrankung verläuft häufig schleichend weswegen sie meist sehr spät erkannt wird. Daher stammt der größte Teil des derzeitigen Wissens über die Sjögren Erkrankung von Patient*innen mit langjähriger Erkrankung. Die Symptome der Patient*innen im Frühstadium der Erkrankung, die initialen immunologischen Veränderungen und die frühen Veränderungen der Speichel- und Tränendrüsen sind völlig unbekannt. Daher gibt es derzeit auch keine Biomarker für die Frühdiagnose der Sjögren Erkrankung. Das vorliegende Projekt ist eine Zusammenarbeit zwischen universitären Zentren in Graz (Österreich) und Brest (Frankreich) und zielt darauf ab, die anfänglichen immunologischen Veränderungen der Sjögren Erkrankung aufzudecken und so die Entstehung der Erkrankung besser zu verstehen. \r\nUm dieses Ziel zu erreichen werden im vorliegenden Projekt etwa 140 Menschen mit hohem Risiko für die Entwicklung einer Sjögren Erkrankung über mehrere Jahre begleitet und eingehend untersucht. Die Methodik verbindet klinische Forschung mit modernsten Labortechniken. Mit Hilfe fortschrittlicher Instrumente werden im Rahmen der Studie eingehende Profile des Immunsystems erstellt. Techniken wie die Einzelzell-RNA-Sequenzierung und Einsatz künstlicher Intelligenz zur Diagnosevorhersage sind integrale Bestandteile des innovativen Forschungsansatzes. Mithilfe der gewonnenen Daten können immunologische Veränderungen von Studienteilnehmer*innen, die im Laufe des Beobachtungszeitraumes eine Sjögren Erkrankung entwickeln, exakt identifiziert und eingeordnet werden. Diese Erkenntnisse sollen das Verständnis zur Entstehung und die Früherkennung der Sjögren Erkrankung revolutionieren.\r\n\r\n", "en": "Sjögren's disease (also known as primary Sjögren's syndrome) is an autoimmune disease in which the body's own immune system attacks and destroys the salivary and lacrimal glands. Vital organs such as the kidneys and lungs can also be affected. The disease often progresses insidiously, which is why it is usually diagnosed very late. It is therefore clear that the majority of current knowledge about Sjögren's disease is derived from patients who have had the disease for many years. In contrast, we know little about the initial immunological events, the symptoms of patients in the early stages of the disease or the early changes in the salivary and lacrimal glands. This means that there are currently no biomarkers for the early diagnosis of Sjögren's disease. This project is a collaboration between university centres in Graz (Austria) and Brest (France). Its aim is to uncover the initial immunological changes of Sjögren's disease in order to better understand the pathogenesis of the disease. \r\nWe will achieve this goal by following and examining in detail around 140 participants at high risk of developing Sjögren's disease over several years. The methodology combines clinical research with state-of-the-art laboratory techniques. The study will create detailed profiles of the immune system using advanced instruments. Techniques such as single-cell RNA sequencing and the use of artificial intelligence for diagnosis prediction are fundamental to this innovative research approach. The data obtained will precisely identify and classify immunological changes in study participants who develop Sjögren's disease during the observation period. These findings will transform our understanding of the development and early diagnosis of Sjögren's disease.\r\n" }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2029-12-31T01:00:00+01:00", "end_effective": "2029-12-31T01:00:00+01:00", "assignment": "2024-10-02T16:37:19+02:00", "program": 111, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 3, "manager": 53560, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PIN3316924", "ethics_committee": null, "edudract_number": null, "persons": [ "8412-51002-12", "8412-53560-10", "8412-85048-12", "8412-98028-12", "8412-101167-12", "8412-108758-12", "8412-105947-12", "8412-111407-12", "8412-120209-12", "8412-120630-12" ] }, { "id": 8573, "title": { "de": "Integrierter Ansatz zur Gewebsheilung: Ein bioaktives magnetisches Pflaster mit Hyperthermie und immobilisiertem Humanserumalbumin", "en": "Integrative approach to tissue healing: A bioactive magnetic patch with hyperthermia and immobilized human serum albumin" }, "short": "BIMA-Patch", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-12-19T15:25:02+01:00", "program": 207, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 1, "manager": 124253, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": "BA 07/2025", "ethics_committee": null, "edudract_number": null, "persons": [ "8573-124253-10" ] }, { "id": 8572, "title": { "de": "Biologische Chelatbildner zur Behandlung von Metallionenüberladung: Eine vergleichende Studie mit traditionellen chemischen Chelatoren", "en": "Biological chelation agents for metal ion overload: A comparative study\r\nwith traditional chemical chelators" }, "short": "Bio-Chem-Chel ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-12-19T14:55:05+01:00", "program": 203, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 3, "manager": 124253, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": "ASEA 11/2024", "ethics_committee": null, "edudract_number": null, "persons": [ "8572-124253-10" ] }, { "id": 9076, "title": { "de": "MetAGE: Metabolische Kontrolle von Altern & Krankheit (Zusatzfinanzierung des FWF-geförderten Cluster of Excelence; CoE14)", "en": "MetAGE: Metabolische Kontrolle von Altern & Krankheit (Zusatzfinanzierung des FWF-geförderten Cluster of Excelence; CoE14)" }, "short": "MetAGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-07-07T18:11:47+02:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 1, "manager": 91207, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9076-91207-10" ] }, { "id": 8636, "title": { "de": "LUMES: Lichtaktive Mikropartikel bei degnerativen Augenerkrankungen", "en": "LUMES: Light-Utilizing Microparticles for Eye Sight" }, "short": "LUMES:", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-02-03T14:38:00+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 99325, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8636-99325-10", "8636-114030-12" ] }, { "id": 8362, "title": { "de": "MEK Inhibition bei RAS-mutierter/EZH2-inaktivierter CMML", "en": "MEK inhibition in RAS-mutated/EZH2-inactivated CMML" }, "short": null, "url": null, "abstract": { "de": "Forschungskontext/theoretischer Rahmen:\r\nDie chronische myelomonozytäre Leukämie (CMML) ist eine aggressive hämatopoetische Neoplasie, die häufig auf Aberrationen zurückzuführen ist, die die RAS-Onkogene verändern (RASmut). Leider sind die derzeitigen therapeutischen Ansätze für RASmut-CMML-Patienten unzureichend. Wir zeigen, dass RASmut bei CMML häufig mit inaktivierenden Aberrationen des epigenetischen Modifikators EZH2 (EZH2inact) einhergeht. In-vitro-Zellkulturstudien zeigen, dass myeloische Zellen mit RASmut/EZH2inact eine Hyperaktivierung der RAS-Signaltransduktion aufweisen und besonders stark auf eine RAS-MAPK/ERK-Inhibition mit MEK-Inhibitoren (MEKi) reagieren.\r\n\r\nHypothesen/Forschungsfragen/Zielsetzungen:\r\nForschungsfrage: \r\nWir fragen, ob unterschiedliche pharmakologische Ansätze therapeutisch auf RASmut/EZH2inact CMML abzielen können.\r\nHypothese: \r\nWir stellen die Hypothese auf, dass RASmut und EZH2inact synergistisch RAS-Signalwege in CMML aktivieren und eine erhöhte Empfindlichkeit gegenüber MEKi verleihen.\r\nZielsetzungen: \r\nDurch die strategische Einbindung unserer Biobank mit klinisch gut annotierten Patientenproben in modernste In-vitro- und In-vivo-Ansätze werden wir zunächst unser Wissen über die Auswirkungen des gemeinsamen Auftretens von RASmut/EZH2inact auf die RAS-MAPK/ERK-Signalübertragung bei CMML erweitern. Anschließend werden wir die MEKi-Therapie in diesen Modellen analysieren und nach einer bevorzugten Empfindlichkeit des RASmut/EZH2inact-Genotyps fragen. Schließlich werden wir die Auswirkungen von MEKi auf RASmut/EZH2inact CMML-Leukämie-Stammzellen (LSC) und die klonale Evolution untersuchen. \r\n\r\nHerangehensweise/Methoden:\r\nWir werden zunächst die Auswirkungen von EZH2inact auf die Aktivierung der RASmut-Signalübertragung in transgenen In-vivo-Mausmodellen, primären CMML-Patientenproben und von Patienten stammenden Xenografts (PDX) untersuchen. Diese Analysen werden die durchflusszytometrische Bewertung des RAS-signalisings in hämatopoetischen Stamm- und Vorläuferzellen (HSPC) und LSC umfassen. Anschließend werden wir diese Modelle verwenden, um die Auswirkungen des gleichzeitigen Auftretens von RASmut/EZH2inact auf MEKi zu bewerten. Letztendlich wollen wir das therapeutische Potenzial von MEKi zur Heilung von RASmut/EZH2inact CMML bewerten. Daher werden wir die Auswirkungen der MEKi-Behandlung auf RASmut/EZH2inact-HSPC-Kompartimente, CMML-LSC und die klonale Evolution der CMML untersuchen. \r\n\r\nGrad der Originalität/Innovation:\r\nDie gezielte Beeinflussung der aberranten RAS-Signalübertragung ist seit Jahrzehnten ein wichtiger Forschungsschwerpunkt. Obwohl seit kurzem direkte RAS-Inhibitoren der nächsten Generation zur Verfügung stehen, war der therapeutische Nutzen für RASmut-CMML-Patienten begrenzt. Dieses Projekt untersucht einen neuartigen Ansatz und schlägt vor, dass eine erfolgreiche molekular gesteuerte Behandlung bei RASmut CMML den Einfluss von koexistierenden und funktionell interagierenden Läsionen berücksichtigen muss.\r\n\r\nBeteiligte Hauptforscher:\r\nArmin Zebisch, der über eine langjährige Erfahrung auf dem Gebiet der RAS-Signalübertragung bei myeloischen Neoplasien verfügt, wird der Hauptforscher sein. Er wird von klinischen Hämatologen und Grundlagenforschern unterstützt, die über profunde Kenntnisse der CMML und der in diesem Projekt verwendeten Modelle verfügen. Ein Doktorand und ein Techniker werden sein Laborteam bei der Durchführung dieses Projekts unterstützen.\r\n", "en": "Wider research context/theoretical framework:\r\nChronic myelomonocytic leukemia (CMML) is an aggressive hematopoietic neoplasia and is frequently driven by aberrations modifying the RAS oncogenes (RASmut). Unfortunately, current therapeutic approaches for RASmut CMML patients are insufficient. We demonstrate that RASmut in CMML often co-occur with inactivating aberrations of the epigenetic modifier EZH2 (EZH2inact). In-vitro cell culture studies reveal that RASmut/EZH2inact myeloid cells exhibit RAS-signaling hyperactivation and might be preferentially sensitive to RAS-MAPK/ERK inhibition with MEK inhibitors (MEKi).\r\n\r\nHypotheses/research questions/objectives:\r\nResearch question: \r\nWe ask whether distinctive pharmacological approaches can therapeutically target RASmut/EZH2inact CMML.\r\nHypothesis:\r\nWe hypothesize that RASmut and EZH2inact synergistically activate RAS-signaling pathways in CMML and confer increased sensitivity to MEKi.\r\nObjectives: \r\nBy strategically incorporating our biobank with clinically well-annotated patient specimens into state-of-the-art in-vitro and in-vivo approaches, we will initially extend our knowledge on the effects of RASmut/EZH2inact co-occurrence on RAS-MAPK/ERK signaling in CMML. We will then analyze MEKi therapy within these models and ask for preferential sensitivity in the RASmut/EZH2inact genotype. Ultimately, we will assess the effects of MEKi on RASmut/EZH2inact CMML-leukemic stem cells (LSC) and clonal evolution. \r\n\r\nApproach/methods:\r\nWe will initially elaborate on the effects of EZH2inact on the activation of RASmut-signaling in transgenic murine in-vivo models, primary CMML patient specimens, and patient-derived xenografts (PDX). These analyses will include the flow-cytometry-based assessment of RAS-signaling in hematopoietic stem and progenitor cells (HSPC) and LSC. We will then use these models to assess the effects of RASmut/EZH2inact co-occurrence on MEKi. Ultimately, we will aim to assess the therapeutic potential of MEKi to cure RASmut/EZH2inact CMML. Therefore, we will study the effects of MEKi treatment on RASmut/EZH2inact HSPC compartments, CMML-LSC and clonal evolution of CMML. \r\nLevel of originality/innovation\r\nTargeting aberrant RAS signaling has been a significant focus of research for the last decades. Despite the recent advent of direct next-generation RAS inhibitors, the therapeutic benefit for RASmut CMML patients was limited. This project assesses a novel approach and proposes that successful molecular-guided treatment in RASmut CMML must consider the influence of co-existing and functionally interacting lesions.\r\nPrimary researchers involved\r\nArmin Zebisch has a strong track record on RAS-signaling in myeloid neoplasms and will be the principal investigator. He will be supported by clinical hematologists and basic researchers with profound expertise in CMML and the models used within this project. A PhD student and technician will further support his lab team in executing this project.\r\n" }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2028-01-01T01:00:00+01:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-08-21T15:56:58+02:00", "program": 72, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 57402, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PAT 1753824", "ethics_committee": null, "edudract_number": null, "persons": [ "8362-57402-10", "8362-97430-12", "8362-97983-12", "8362-50116-12" ] }, { "id": 8463, "title": { "de": "Fortschritte in der Sepsiserkennung: Fortschrittliche magnetischen Anreicherung für eine frühere Diagnose", "en": "Advancing sepsis detection: Pioneering magnetic enrichment for earlier diagnosis" }, "short": "SEPMAG", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-10-23T11:36:06+02:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 4, "manager": 124253, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 35 ], "funder_projectcode": "EI 1326/1-1", "ethics_committee": null, "edudract_number": null, "persons": [ "8463-124253-10" ] }, { "id": 8728, "title": { "de": "Vergleich der konvektive Wasserdampfablation (convective water vapor energy, WAVE™)\r\nmit dem Rezum™-System versus Holmium Laser Enukleation der Prostata (HoLEP) versus\r\nbipolare transurethrale Resektion der Prostata (TUR-P) bei Patienten mit benignen\r\nProstatasyndrom (BPS) – eine randomisierte Studie", "en": "Comparison of Convective Water Vapor Ablation (convective water vapor energy, WAVE™)\r\nwith the Rezum™ System versus Holmium Laser Enucleation of the Prostate (HoLEP) versus\r\nBipolar Transurethral Resection of the Prostate (TUR-P) in Patients with Benign Prostatic\r\nSyndrome (BPS) – A Randomized Study" }, "short": "Vektor", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2030-12-31T01:00:00+01:00", "end_effective": "2030-12-31T01:00:00+01:00", "assignment": "2025-03-17T15:43:09+01:00", "program": null, "subprogram": null, "organization": 14056, "category": 10, "type": 10, "partner_function": 3, "manager": 121670, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": 12, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8728-121670-10" ] }, { "id": 8299, "title": { "de": "Energetik-Transkriptions Kopplung im hypertensiven Herzen", "en": "Energetics-transcription coupling in hypertensive heart" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2029-12-31T01:00:00+01:00", "end_effective": "2029-12-31T01:00:00+01:00", "assignment": "2024-07-17T18:19:55+02:00", "program": 110, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 62747, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "STA 194", "ethics_committee": null, "edudract_number": null, "persons": [ "8299-62747-10", "8299-75758-12", "8299-105142-12", "8299-110709-12", "8299-117943-12", "8299-131037-12", "8299-122231-12" ] }, { "id": 8532, "title": { "de": "Identifizierung Glykosylierungs-bezogener Biomarker\r\nzur Stratifizierung des Schweregrads beim chronischen Fatigue Syndrom", "en": "Exploring the Glycome: Identifying Glycosylation-Related Biomarkers\r\nfor severity stratification in Chronic Fatigue Syndrome" }, "short": "GlycoExplore-CFS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-11-27T12:11:08+01:00", "program": null, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 1, "manager": 120271, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1844 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8532-120271-10" ] }, { "id": 8579, "title": { "de": "Eine offene, multizentrische Folgestudie an erwachsenen Patienten mit Diabetes mellitus Typ 1, zur Untersuchung der Langzeitwirkung der Verapamil-SR-Therapie auf die Erhaltung der Beta-Zell-Funktion", "en": "An open-label extension multi-centre trial in adult subjects diagnosed with Type 1 diabetes mellitus exploring the effect of long-term Verapamil SR therapy on the preservation of beta cell function." }, "short": "Ver-A-Long", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2027-12-31T01:00:00+01:00", "end_effective": "2027-12-31T01:00:00+01:00", "assignment": "2025-01-04T08:35:44+01:00", "program": null, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 3, "manager": 51831, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2528 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8579-51831-10" ] }, { "id": 8635, "title": { "de": "Untersuchung der Pathologie pustulöser Hautkrankheiten: Integration von Spatial Transcriptomics und In-situ-Analysen von seltenen Krankheiten", "en": "Deciphering Pustular Skin Disease Pathology: Integrating Spatial Transcriptomics and In Situ Analysis of rare diseases " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-02-03T14:35:54+01:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 88082, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8635-88082-10" ] }, { "id": 8425, "title": { "de": "Nanoträger für die selektive Behandlung von HER2+ Brustkrebs", "en": "Nanocarriers for selective HER2+ breast cancer treatment" }, "short": "MIP-Magic", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-10-01T02:00:00+02:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-03-31T02:00:00+02:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2024-10-07T16:23:56+02:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 3, "manager": 124253, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8425-124253-10" ] }, { "id": 8707, "title": { "de": "Pilotprojekt: 5 Präventionsfaktoren der Grazer Gehirngesundheit", "en": "Pilot project: 5 Preventive Factors of brain health" }, "short": "5P_3G", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-27T01:00:00+01:00", "begin_effective": "2025-01-27T01:00:00+01:00", "end_planned": "2026-01-27T01:00:00+01:00", "end_effective": "2026-01-27T01:00:00+01:00", "assignment": "2025-03-04T18:18:04+01:00", "program": null, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 66708, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8707-66708-10" ] }, { "id": 8589, "title": { "de": "Rejuvenated yeasts for better biorefineries", "en": "Rejuvenated yeasts for better biorefineries" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-31T01:00:00+01:00", "begin_effective": "2025-01-31T01:00:00+01:00", "end_planned": "2028-01-30T01:00:00+01:00", "end_effective": "2028-01-30T01:00:00+01:00", "assignment": "2025-01-10T10:29:19+01:00", "program": 94, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 1, "manager": 113130, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8589-113130-10", "8589-132237-12" ] }, { "id": 8585, "title": { "de": "AKUTE EFFEKTE UND VERTRÄGLICHKEIT VON TRAININGSBELASTUNGEN BEI LUNGENKREBSPATIENTINNEN UNTER IMMUNTHERAPIE", "en": "ACUTE EFFECTS AND TOLERABLITY OF EXERCISE IN LUNG CANCER PATIENTS UPON IMMUNOTHERAPY" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-02-01T01:00:00+01:00", "begin_effective": "2025-02-01T01:00:00+01:00", "end_planned": "2026-02-01T01:00:00+01:00", "end_effective": "2026-02-01T01:00:00+01:00", "assignment": "2025-01-07T16:03:50+01:00", "program": null, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 1, "manager": 71794, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": "2024 - FB Wissenschaft 10_24", "ethics_committee": null, "edudract_number": null, "persons": [ "8585-71794-10" ] }, { "id": 8622, "title": { "de": "GREENS ", "en": "GREENS Responsible microrobots" }, "short": "GREENS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-10-01T02:00:00+02:00", "begin_effective": "2025-02-01T01:00:00+01:00", "end_planned": "2028-09-30T02:00:00+02:00", "end_effective": "2029-01-31T01:00:00+01:00", "assignment": "2025-01-24T11:20:32+01:00", "program": 209, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 2, "manager": 107189, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "101169173 — GREENS", "ethics_committee": null, "edudract_number": null, "persons": [ "8622-107189-10" ] }, { "id": 8548, "title": { "de": "Multivariater optoakustischer Sensor für Langzeitmonitoring bei Diabetes mellitus", "en": "Multivariate optoacoustic sensor for longitudinal diabetes monitoring" }, "short": "MOSAIC_(vormals LongDip)", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-02-01T01:00:00+01:00", "begin_effective": "2025-02-01T01:00:00+01:00", "end_planned": "2029-01-31T01:00:00+01:00", "end_effective": "2029-01-31T01:00:00+01:00", "assignment": "2024-12-10T13:27:09+01:00", "program": 218, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 1, "manager": 51831, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8548-51831-10" ] }, { "id": 8648, "title": { "de": "In-silico-Charakterisierung der 1q21-Amplifikation bei fortgeschrittenem Lungenadenokarzinom", "en": "In silico characterization of 1q21 amplification in advanced lung adenocarcinoma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-02-01T01:00:00+01:00", "end_planned": "2026-05-31T02:00:00+02:00", "end_effective": "2026-01-31T01:00:00+01:00", "assignment": "2025-02-13T10:16:53+01:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 1, "manager": 124172, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8648-133063-12", "8648-124172-10" ] } ] }{ "count": 2183, "next": "