Project List
List projects.
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GET /v1/research/project/?format=api&offset=2060&ordering=end_effective
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=2080&ordering=end_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=2040&ordering=end_effective", "results": [ { "id": 8633, "title": { "de": "Messung der bukkalen Knochen- und Mukosadicke mittels Ultraschall und künstlicher Intelligenz in der dentalen Implantologie", "en": "Ultrasound assessment of buccal bone and mucosal thickness using artificial intelligence aided segmentation in dental implantology" }, "short": "Ultimate-Project", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-05-01T02:00:00+02:00", "begin_effective": "2023-05-01T02:00:00+02:00", "end_planned": "2026-01-01T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-01-31T15:35:22+01:00", "program": null, "subprogram": null, "organization": 14111, "category": 10, "type": 10, "partner_function": 4, "manager": 125157, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 35 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8633-125157-10" ] }, { "id": 8140, "title": { "de": "Entschlüsselung von Alzheimer: \r\nTRPC1 als zentrale Figur bei Protein-Entfaltung und Cholesterin-Biosynthese\r\n", "en": "Deciphering Alzheimer's: \r\nTRPC1 as a central player in protein unfolding and cholesterol biosynthesis" }, "short": null, "url": null, "abstract": { "de": "Hintergrund: Die Alzheimer-Krankheit (AD) ist eine irreversible und tödliche Form von Demenz, unterteilt in sporadische (SAD) und familiäre AD (FAD). FAD, mit frühem Beginn aufgrund spezifischer Genmutationen, steht im Gegensatz zu SAD, das einen späten Beginn und eine unklare Ursache aufweist. Die Ca2+-Homöostase- Hypothese von SAD legt nahe, dass eine frühzeitige Ca2+-Dysregulation mit der Fehlfaltung von Proteinen und der Anreicherung von Cholesterin einhergeht. Das endoplasmatische Retikulum (ER) ist entscheidend für die Regulation des intrazellulären Ca2+, die Verarbeitung von Proteinen und die Lipid-Biosynthese. Die Familie der transienten Rezeptorpotenzial-Kanäle (TRPC1-7) umfasst TRPC1, der im Hippocampus stark exprimiert wird. Während TRPC2-7 ausschließlich in der Plasmamembran gefunden werden, befindet sich TRPC1 auch in der ER- Membran.\r\nHypothese: TRPC1 könnte an der Regulation von Ca2+, der Synthese von Proteinen und Cholesterin im ER beteiligt sein.\r\nErgebnisse: Vorläufige Experimente zeigten, dass TRPC1 den Ca2+-Leck aus dem ER signifikant verstärkte, den Cholesterinspiegel in TRPC1-transfizierten HEK293-Zellen erhöhte, den Cholesterinspiegel in den Hippocampi transgener Mäuse im Alter veränderte und die Expression von Transkriptionsfaktoren beeinflusste, die an der Proteinfaltung beteiligt sind.\r\nFazit: Eine weitere Erforschung der Rolle von TRPC1 im ER könnte ihn als potenzielles pharmazeutisches Ziel in der AD-Behandlung etablieren.", "en": "Background: Alzheimer’s disease (AD) is an irreversible and fatal form of dementia, divided into sporadic (SAD) and familial AD (FAD). FAD, with early onset due to specific gene mutations, contrasts SAD, with late onset and an unclear cause. The Ca2+ homeostasis hypothesis of SAD suggests early Ca2+ dyshomeostasis links to protein misfolding and cholesterol accumulation. The endoplasmic reticulum (ER) is crucial, managing intracellular Ca2+, protein processing, and lipid biosynthesis. The transient receptor potential canonical family (TRPC1-7) includes TRPC1, highly expressed in the hippocampus. While TRPC2-7 target the plasma membrane, TRPC1 is also found in the ER membrane.\r\nHypothesis: TRPC1 may be involved in Ca2+ handling, protein, and cholesterol synthesis in the ER.\r\nResults: Preliminary experiments showed TRPC1 increased Ca2+ leak from the ER, elevated cholesterol in TRPC1- transfected HEK293 cells, altered cholesterol levels in hippocampi from aged transgenic mice, and affected expression of transcription factors involved in protein folding.\r\nConclusion: Further exploring TRPC1 role in the ER could establish it as a potential pharmaceutical target in AD treatment." }, "begin_planned": "2024-03-01T01:00:00+01:00", "begin_effective": "2024-03-01T01:00:00+01:00", "end_planned": "2025-02-28T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-04-16T14:17:18+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 90337, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8140-90337-10", "8140-116421-12", "8140-122690-12" ] }, { "id": 8188, "title": { "de": "Pilztranslokation über den Darm gemessen durch 1,3-Beta-D-Glukan und seine Rolle in Patient:innen mit Leberzirrhose", "en": "Gut fungal translocation measured by 1,3-Beta-D-Glucan and its role in patients with liver cirrhosis" }, "short": "BDG-Cirrhosis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-08-01T02:00:00+02:00", "begin_effective": "2024-08-01T02:00:00+02:00", "end_planned": "2026-01-01T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-05-07T15:35:19+02:00", "program": null, "subprogram": null, "organization": 29164, "category": 10, "type": 10, "partner_function": 4, "manager": 115781, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 203 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8188-115781-10" ] }, { "id": 9508, "title": { "de": "PAEC Dysfunktion in SSc mit Lungenbeteiligung", "en": "PAEC Dysfunction in SSC with lung involvement" }, "short": "PAEC Dysfunction_SSC_Lungenbetlg", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2026-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-12-18T11:39:10+01:00", "program": null, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 61540, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9508-61540-10" ] }, { "id": 9252, "title": { "de": "Magnetische Analyse von Biomarkern", "en": "Magnetic Analysis of Biomarkers" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2026-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-10-03T11:02:07+02:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 4, "manager": 113130, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9252-113130-10" ] }, { "id": 9270, "title": { "de": "Strukturiertes Kommunikationstraining mit standardisierten Patient*innen für die antenatale neonatologische Beratung bei drohender Frühgeburt", "en": "Antenatal Counselling Training for expected preterm delivery using structured communication training with standardized patients" }, "short": "ACT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-10-01T02:00:00+02:00", "begin_effective": "2025-10-01T02:00:00+02:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-10-15T18:28:23+02:00", "program": null, "subprogram": null, "organization": 14094, "category": 10, "type": 10, "partner_function": 1, "manager": 68534, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 97 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9270-68534-10" ] }, { "id": 8636, "title": { "de": "LUMES: Lichtaktive Mikropartikel bei degnerativen Augenerkrankungen", "en": "LUMES: Light-Utilizing Microparticles for Eye Sight" }, "short": "LUMES:", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-01-01T01:00:00+01:00", "begin_effective": "2025-01-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-02-03T14:38:00+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 99325, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8636-99325-10" ] }, { "id": 9483, "title": { "de": "Gestörtes Lipid-Signaling in Typ II Alveolarepithelzellen bei Lungenfibrose", "en": "Lipid signalling impairment in alveolar type II cells in pulmonary fibrosis" }, "short": "Lipid-Signaling_Typ II Alveloarepithelz", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2025-12-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-12-15T09:54:58+01:00", "program": null, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 57409, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9483-57409-10", "9483-133023-12" ] }, { "id": 6857, "title": { "de": "Predicting Cardiovascular Events Using Machine Learning", "en": "Predicting Cardiovascular Events Using Machine Learning" }, "short": "PRE-CARE ML", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-01-01T01:00:00+01:00", "begin_effective": "2022-01-01T01:00:00+01:00", "end_planned": "2024-12-31T01:00:00+01:00", "end_effective": "2027-01-01T01:00:00+01:00", "assignment": "2021-12-21T14:20:28+01:00", "program": 112, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 3, "manager": 58906, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I5898", "ethics_committee": null, "edudract_number": null, "persons": [ "6857-58906-10" ] }, { "id": 7272, "title": { "de": "Die Rolle von Epigenetik und veränderter Zytokinantwort in Stimmlippen-Fibroblasten von Reinke Ödem Patienten", "en": "Role of epigenetics and differential cytokine response in vocal fold fibroblasts of Reinke's edema patients" }, "short": "RE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-08-01T02:00:00+02:00", "begin_effective": "2023-01-16T01:00:00+01:00", "end_planned": "2025-07-31T02:00:00+02:00", "end_effective": "2027-01-15T01:00:00+01:00", "assignment": "2022-11-29T15:14:56+01:00", "program": 72, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 69755, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P36067", "ethics_committee": null, "edudract_number": null, "persons": [ "7272-50670-12", "7272-50698-12", "7272-50899-12", "7272-69755-10", "7272-77116-12", "7272-82902-12", "7272-97517-12", "7272-98190-12", "7272-88652-12", "7272-103118-12", "7272-129518-12" ] }, { "id": 6349, "title": { "de": "Central Repository for Digital Pathology", "en": "Central Repository for Digital Pathology" }, "short": "BIGPICTURE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-01-01T01:00:00+01:00", "begin_effective": "2021-02-01T01:00:00+01:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2020-11-30T11:10:17+01:00", "program": 109, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": " 945358", "ethics_committee": null, "edudract_number": null, "persons": [ "6349-51663-10" ] }, { "id": 8648, "title": { "de": "In-silico-Charakterisierung der 1q21-Amplifikation bei fortgeschrittenem Lungenadenokarzinom", "en": "In silico characterization of 1q21 amplification in advanced lung adenocarcinoma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-02-01T01:00:00+01:00", "end_planned": "2026-05-31T02:00:00+02:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2025-02-13T10:16:53+01:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 1, "manager": 124172, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8648-133063-12", "8648-124172-10" ] }, { "id": 7297, "title": { "de": "MICRObiome Biobanking (RI) Enabler", "en": "MICRObiome Biobanking (RI) Enabler" }, "short": "MICROBE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-02-01T01:00:00+01:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2027-01-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2022-12-07T11:19:47+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "101094353", "ethics_committee": null, "edudract_number": null, "persons": [ "7297-51870-12", "7297-51663-10", "7297-129561-12" ] }, { "id": 6869, "title": { "de": "Peptidomimetisce INhibitoren für CRAC-Kanal", "en": "Light-activatable peptidomimetic inhibitors for CRAC-channel" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-11-01T01:00:00+01:00", "begin_effective": "2021-11-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2022-01-05T15:23:09+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 86144, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I5611", "ethics_committee": null, "edudract_number": null, "persons": [ "6869-86144-10", "6869-116508-12" ] }, { "id": 8668, "title": { "de": "Entschlüsselung molekularer Signalwege der Sarkopenie bei chronischer Niereninsuffizienz", "en": "Deciphering molecular pathways of sarcopenia in chronic kidney disease" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-02-01T01:00:00+01:00", "begin_effective": "2025-02-01T01:00:00+01:00", "end_planned": "2027-01-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2025-02-17T15:00:01+01:00", "program": null, "subprogram": null, "organization": 14084, "category": 10, "type": 10, "partner_function": 1, "manager": 100601, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8668-100601-10" ] }, { "id": 8021, "title": { "de": "Teaching critical thinking in science through nanolearning and virtual exchange principles", "en": "Teaching critical thinking in science through nanolearning and virtual exchange principles" }, "short": " NANO-THINK ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-02-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2024-02-05T13:49:53+01:00", "program": 220, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 2, "manager": 57932, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8021-57932-10" ] }, { "id": 9576, "title": { "de": "Synthese und Modifizierung von Briciclib-Phosphonat-Analoga zur topischen Behandlung der Psoriasis", "en": "Synthesis and modification of Briciclib phosphonate analogs for the topical treatment of psoriasis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-02-01T01:00:00+01:00", "begin_effective": "2026-02-01T01:00:00+01:00", "end_planned": "2027-01-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2026-02-02T10:10:25+01:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 84167, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9576-84167-10" ] }, { "id": 9273, "title": { "de": "Beurteilung der Passgenauigkeit von nicht originalen Abutments bei verschraubten implantatgetragenen Brücken", "en": "Fit evaluation of nonoriginal abutments in the partial screw-retained implant-supported prosthesis on internal connection implants" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-10-20T02:00:00+02:00", "begin_effective": "2025-10-20T02:00:00+02:00", "end_planned": "2027-02-01T01:00:00+01:00", "end_effective": "2027-02-01T01:00:00+01:00", "assignment": "2025-10-21T18:05:25+02:00", "program": null, "subprogram": null, "organization": 14111, "category": 10, "type": 10, "partner_function": 4, "manager": 101246, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2591 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9273-101246-10" ] }, { "id": 9468, "title": { "de": "Das Dopaminsystem in einem neuen Cav1.3 Mausmodell einer neurologischen Entwicklungsstörung", "en": "The dopamine system in a new Cav1.3 Ca2+ channelopathy mouse model of a neurodevelopmental disorder" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2026-01-01T01:00:00+01:00", "begin_effective": "2026-01-01T01:00:00+01:00", "end_planned": "2027-02-09T01:00:00+01:00", "end_effective": "2027-02-09T01:00:00+01:00", "assignment": "2025-12-04T12:34:29+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": 136954, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9468-136954-10" ] }, { "id": 7468, "title": { "de": "SFB Lipidhydrolyse: Zusatzfinanzierung Land Steiermark (Förderperiode 2)", "en": "SFB Lipidhydrolyse: add-on Land Steiermark (funding periode 2)" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2027-02-28T01:00:00+01:00", "end_effective": "2027-02-28T01:00:00+01:00", "assignment": "2023-04-05T15:19:16+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 3, "manager": 51904, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7468-51904-10" ] } ] }