Project List
List projects.
Fields
id (integer)
Primary key.
Expansions
To activate relation expansion add the desired fields as a comma separated
list to the expand query parameter like this:
?expand=<field>,<field>,<field>,...
The following relational fields can be expanded:
organizationcategorytypepartner_functionmanagercontactstatusgrantresearcheventstudylanguageprogramfunders
Filters
To filter for exact value matches:
?<fieldname>=<value>
Possible exact filters:
organizationcategorymanagercontactstatusgrantresearchstudylanguagefundersprogram
For advanced filtering use lookups:
?<fieldname>__<lookup>=<value>
All fields with advanced lookups can also be used for exact value matches as described above.
Possible advanced lookups:
begin_planned:gt,gte,lt,ltebegin_effective:gt,gte,lt,lteend_planned:gt,gte,lt,lteend_effective:gt,gte,lt,lte
GET /v1/research/project/?format=api&offset=1920&ordering=end_planned
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1940&ordering=end_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1900&ordering=end_planned", "results": [ { "id": 7984, "title": { "de": "Gewebe-infiltrierende Lymphozyten - Direkte Evaluierung der Rezeptoren ", "en": "Tissue-infiltrating Lymphocytes - Direct Evaluation of Receptors " }, "short": "TIL-DER", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-04-01T02:00:00+02:00", "begin_effective": "2024-04-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2026-09-30T02:00:00+02:00", "assignment": "2024-01-19T12:01:27+01:00", "program": 117, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 97234, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7984-97234-10" ] }, { "id": 8478, "title": { "de": "Veränderung menschlicher Eosinophiler Granulozyten im Alter abhängig vom Geschlecht", "en": "Phenotypic changes of eosinophil granulocytes in aging and sex" }, "short": "Eosinph. Granulozyten_Alter_Geschlecht", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-10-01T02:00:00+02:00", "begin_effective": "2024-10-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2026-03-31T02:00:00+02:00", "assignment": "2024-11-06T09:30:06+01:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 85658, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8478-85658-10" ] }, { "id": 6703, "title": { "de": "Koordination: RESPIMMUN - Immun Modulation Respiratorischer Krankheiten", "en": "Coordination: RESPIMMUN - Immune Modulation in Respiratory Diseases" }, "short": "RESPIMMUN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2021-10-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2021-09-22T13:35:46+02:00", "program": 114, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 3, "manager": 82090, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "DOC 129-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6703-87378-12", "6703-96374-12", "6703-82090-10" ] }, { "id": 6726, "title": { "de": "RESPIMMUN: Zusammenspiel von Entzündungszellen und Basalmembrankomponenten bei der Entstehung von PH ", "en": "RESPIMMUN: Interplay between inflammatory cells and basement membrane components in the development of PH " }, "short": "RESPIMMUN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2021-10-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2021-10-04T13:47:34+02:00", "program": 114, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 4, "manager": 82090, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "DOC 129-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6726-97528-12", "6726-111207-12", "6726-111474-12", "6726-111487-12", "6726-82090-10", "6726-119568-12" ] }, { "id": 6743, "title": { "de": "RESPIMMUN: Immunophänotypisierung des vaskulären Phänotyps bei COPD", "en": "RESPIMMUN: Immunophenotyping the vascular phenotype within COPD" }, "short": "RESPIMMUN Leigh Marsh_subproject", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2021-10-01T02:00:00+02:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2021-10-13T15:25:57+02:00", "program": 114, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 2, "manager": 100911, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "DOC 129-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6743-111474-12", "6743-100911-10" ] }, { "id": 8734, "title": { "de": "ELPHI: Kontaktlos-gesteuerte Implantate für lokale Chemo in Gehirntumoren", "en": "ELPHI: wireless implants for local chemotherapy in brain tumors" }, "short": "ERC get started ELPHI", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-03-01T01:00:00+01:00", "begin_effective": "2025-04-01T02:00:00+02:00", "end_planned": "2025-10-01T02:00:00+02:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2025-03-21T19:29:34+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 99703, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8734-99703-10" ] }, { "id": 7328, "title": { "de": "ANEMONE: Die Antwort in der Mikroumgebung: Resistenz des malignen Pleuramesothelioms gegen alte und neue Medikamente", "en": "ANEMONE: The ANswer within the microEnvironment: Malignant pleural mesothelioma resistance to Old and NEw drugs " }, "short": "ANEMONE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-10-01T02:00:00+02:00", "begin_effective": "2022-11-01T01:00:00+01:00", "end_planned": "2025-10-01T02:00:00+02:00", "end_effective": "2026-08-31T02:00:00+02:00", "assignment": "2023-01-11T10:20:33+01:00", "program": 112, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 1, "manager": 100911, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I6102", "ethics_committee": null, "edudract_number": null, "persons": [ "7328-100911-10", "7328-119328-12" ] }, { "id": 7255, "title": { "de": "Pilot und ATCO aeromedical - Diabetes", "en": "Pilot and ATCO aeromedical - Diabetes" }, "short": "EASA-Diabetes", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-11-01T01:00:00+01:00", "begin_effective": "2023-01-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2022-11-16T13:53:19+01:00", "program": 211, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 3, "manager": 50877, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": 3, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7255-50877-10", "7255-87054-12", "7255-115130-12", "7255-117401-12", "7255-121710-12", "7255-122513-12" ] }, { "id": 7264, "title": { "de": "PHYSIK-BASIERTE MASCHINEN-LERNEN BASIERTE PRÄDIKTION UND RÜCKBILDUNG VON GESTÖRTER NÜCHTERNGLUKOSE", "en": "PHYSICS INFORMED MACHINE LEARNING-BASED PREDICTION AND REVERSION OF IMPAIRED FASTING GLUCOSE MANAGEMENT" }, "short": "PRAESIIDIUM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-11-01T01:00:00+01:00", "begin_effective": "2023-01-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2022-11-22T17:00:14+01:00", "program": 211, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 2, "manager": 50877, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "101095672", "ethics_committee": null, "edudract_number": null, "persons": [ "7264-50877-10", "7264-87054-12", "7264-118223-12" ] }, { "id": 8021, "title": { "de": "Teaching critical thinking in science through nanolearning and virtual exchange principles", "en": "Teaching critical thinking in science through nanolearning and virtual exchange principles" }, "short": " NANO-THINK ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-02-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2024-02-05T13:49:53+01:00", "program": 220, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 2, "manager": 57932, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8021-57932-10" ] }, { "id": 7959, "title": { "de": "Zusammensetzung und Funktion von Immunzellen bei Patient*innen mit und ohne steroidrefraktärer akuter und chronischer Graft-versus-Host-Krankheit nach allogener hämatopoetischer Zelltransplantation", "en": "Immune cell composition and function in patients with and without steroid-refractory acute and chronic graft-versus-host disease after allogeneic hematopoietic cell transplantation" }, "short": "Immune cell composition in GVHD", "url": null, "abstract": { "de": null, "en": "One of the most serious life-threatening complications of allogeneic hematopoietic stem cell transplantation (allo-HCT) is acute and chronic graft-versus-host disease (GVHD). (1,2) The established first-line therapy of acute GVHD is methylprednisolone with an initial dose of 2 mg/kg body weight per day. But, only half of all patients respond to first-line therapy and the so-called steroid-refractory GVHD (SR-GVHD) is associated with a poor long-term prognosis. There is still an urgent need for biomarkers that predict response to glucocorticoid therapy. In a retrospective study we showed that cellular infiltrates of immune cells, like innate lymphoid cells (ILCs) and tissue-resident memory T cells (TRMs), differ at onset of gastrointestinal (GI) GVHD in patients who subsequently respond to glucocorticoid therapy compared to patients developing steroid-refractory disease. Based on these preliminary data, we hypothesize that GVHD affects the composition of immune cell populations in affected tissues, such as skin and GI tract, and cellular and molecular profiles of immune cells from peripheral blood (PB) and tissue biopsies, as well as the GI microbiome, may predict lack of response to glucocorticoid therapy. Furthermore, these cellular and molecular profiles may be prognostic for immune reconstitution after allo-HCT. Therefore, the aim of this study is to identify cellular and molecular profiles of GVHD in patients. \r\nFor this purpose, we will prospectively collect clinical data of patients undergoing allo-HCT at the Clinical Division of Hematology at the Medical University/University Hospital Graz, to create a database and compare patient’s clinical course with immune cell composition as well as function/activation state of the PB determined by flow cytometry and cytokine production, as we GI microbiome analysis and tissue samples (skin and GI) obtained from routine clinical biopsies using immunofluorescence, immunohistochemistry and High-Definition Spatial Transcriptomics (HDST). Results of blood and tissue immune cell analyses, cytokines and data from GI microbiome will be compared to the cli nical data on occurrence and severity of GVHD, response to GVHD therapy and patient outcome.\r\n" }, "begin_planned": "2023-11-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-01-04T15:27:07+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 82501, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894, 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7959-100134-12", "7959-59183-12", "7959-82501-10", "7959-111069-12" ] }, { "id": 6869, "title": { "de": "Peptidomimetisce INhibitoren für CRAC-Kanal", "en": "Light-activatable peptidomimetic inhibitors for CRAC-channel" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-11-01T01:00:00+01:00", "begin_effective": "2021-11-01T01:00:00+01:00", "end_planned": "2025-10-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2022-01-05T15:23:09+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 86144, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I5611", "ethics_committee": null, "edudract_number": null, "persons": [ "6869-86144-10", "6869-116508-12" ] }, { "id": 6706, "title": { "de": "RESPIMMUN - Die Rolle der mehrfach ungesättigten Fettsäuren bei allergischer Lungenentzündung", "en": "RESPIMMUN - Role of poly unsaturated fatty acids in allergic lung inflammation " }, "short": "RESPIMMUN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2021-10-01T02:00:00+02:00", "end_planned": "2025-11-30T01:00:00+01:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2021-09-22T14:11:20+02:00", "program": 114, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 2, "manager": 53252, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "DOC 129-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6706-53252-10" ] }, { "id": 6727, "title": { "de": "RESPIMMUN\r\n", "en": "RESPIMMUN\r\n" }, "short": "RESPIMMUN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-10-01T02:00:00+02:00", "begin_effective": "2021-10-01T02:00:00+02:00", "end_planned": "2025-11-30T01:00:00+01:00", "end_effective": "2025-11-30T01:00:00+01:00", "assignment": "2021-10-04T13:53:34+02:00", "program": 114, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 2, "manager": 60706, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "DOC 129-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6727-60706-10" ] }, { "id": 8077, "title": { "de": "Smart FOX - Smart and Federated Open Data eXchange of citizen-based data donations for clinical research", "en": "Smart FOX - Smart and Federated Open Data eXchange of citizen-based data donations for clinical research" }, "short": "Smart FOX", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-12-01T01:00:00+01:00", "begin_effective": "2024-07-01T02:00:00+02:00", "end_planned": "2025-11-30T01:00:00+01:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2024-03-08T10:12:02+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8077-51663-10" ] }, { "id": 8230, "title": { "de": "Untersuchung von anti EGF-R virus-ähnlicher Partikel", "en": "Testing of anti EGF-R virus-like particles (VLPs)" }, "short": "VLPs", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-06-01T02:00:00+02:00", "begin_effective": "2024-05-01T02:00:00+02:00", "end_planned": "2025-12-30T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2024-05-27T14:59:52+02:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 1, "manager": 50593, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8230-50593-10" ] }, { "id": 6518, "title": { "de": "Entwicklung von interaktiven adaptierbaren und visulisierten qualitativ hochwertigen Gesundheitsinformationen ", "en": "Human-Centered Interactive Adaptive Visual\r\nApproaches in High-Quality Health Information" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2021-01-01T01:00:00+01:00", "begin_effective": "2021-05-01T02:00:00+02:00", "end_planned": "2025-12-30T01:00:00+01:00", "end_effective": "2026-10-31T01:00:00+01:00", "assignment": "2021-04-08T14:18:36+02:00", "program": 113, "subprogram": null, "organization": 27964, "category": 10, "type": 10, "partner_function": 2, "manager": 51098, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 11-B", "ethics_committee": null, "edudract_number": null, "persons": [ "6518-51098-10" ] }, { "id": 8562, "title": { "de": "Pilotprojekt Telemedizin in der klinisch-forensischen Untersuchung", "en": "-" }, "short": "Telemedizin_klin-foren_Untersuchungen", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-07-01T02:00:00+02:00", "begin_effective": "2024-06-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2024-12-12T14:49:41+01:00", "program": null, "subprogram": null, "organization": 14019, "category": 10, "type": 10, "partner_function": 4, "manager": 115441, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8562-115441-10" ] }, { "id": 6787, "title": { "de": "Apolipoprotein AI (apo-AI) Mimetische \r\nPeptid-Lipid-Assemblies", "en": "Apolipoprotein AI (apo-AI) Mimetic \r\nPeptide Lipid Assemblies" }, "short": "AAMLA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-01-01T01:00:00+01:00", "begin_effective": "2022-01-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-11-30T01:00:00+01:00", "assignment": "2021-11-17T15:51:22+01:00", "program": 111, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 2, "manager": 53252, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I5703", "ethics_committee": null, "edudract_number": null, "persons": [ "6787-53252-10" ] }, { "id": 7363, "title": { "de": "Digitale Zwillinge für die Behandlung von Vorhofflimmern", "en": "Digital Twins to Treat Atrial Fibrillation" }, "short": "DAWN-AF", "url": null, "abstract": { "de": "Vorhofflimmern (VHF) ist die häufigste Arrhythmie des Herzens. Bei VHF handelt es sich um eine fortschreitende Erkrankung des Herzens. Je länger VHF andauert, umso schwieriger ist die Behandlung, und das Risiko Folgeschäden wie Schlaganfälle, Demenz oder Herzinsuffizienz zu erleiden nimmt zu. Die effektivste Therapie für VHF ist die Ablationstherapie mittels Herzkatheter, eine Prozedur, bei der Gewebe in den Vorhöfen des Herzens zerstört wird um die Ausbreitungspfade von elektrischen Wellen einzuschränken. Aktuelle Therapieformen sind generisch, die Variabilität der Patienten hinsichtlich der Struktur der Vorhöfe wird nicht berücksichtigt, weshalb VHF-Symptome auch nach anfänglich positiver Therapie häufig zurückkehren.\r\n\r\nDas Ziel des DAWN-AF Projektes ist es, einen personalisierten medizinischen Ansatz zu entwickeln, der auf Computermodellierung basiert. Konkret werden digitale Zwillinge der Vorhöfe des Herzens entwickelt. Diese können zur verbesserten Planung der VHF-Ablation im Computer verwendet werden, um ein Wiederauftreten von VHF zu verhindern. Dazu werden präoperative Messungen wie das Elektrokardiogramm und tomographische Bildgebung (MRT/CT) verwendet, um anatomisch und funktionell detaillierte digitale Zwillinge zu erstellen. Da diese Daten jedoch nicht ausreichen, um die Vorhöfe eindeutig zu charakterisieren, wird für jeden Patienten ein Satz an potenziellen digitalen Zwillingen erstellt, um dann für jede einzelne Variation die jeweils ideale Ablationsbehandlung zu bestimmen. Anhand von invasiven Messungen während des Eingriffs wird dann derjenige digitale Zwilling ausgewählt, der am besten zum Patienten passt. Eine wirtschaftliche Analyse der VHF-Therapie wird den Nutzen unseres mittels digitaler Zwillinge personalisierten Therapiezugangs bewerten. Dieser Nutzen ergibt sich aus einer frühzeitigen präventiven Behandlung, aus einem länger anhaltenden Therapieerfolg, aus einer verkürzten Eingriffsdauer und einer Reduktion des Eingriffsrisikos.\r\n", "en": "Atrial Fibrillation (AF) is the most common cardiac arrhythmia. Since AF is progressive, the longer one has it, the harder it is to treat, and the risks of stroke, dementia and heart failure increase. The most effective treatment is catheter ablation therapy, a procedure that strategically destroys tissue to restrict propagation of electrical waves. However, approaches are currently generic, ignoring patient variability in atrial structure, and AF usually recurs. We aim to develop a personalised medicine approach based on computer modelling, to use digital twins to plan AF ablation to prevent recurrence. We propose to use preoperative measurements, imaging (MRI/CT) and the ECG, to build digital twins. However, these data are insufficient to uniquely characterize the atria, so we will build sets of potential digital twins for each patient, each of which will have its ideal ablation treatment determined. Invasive measurements acquired during the ablation procedure will be then used to select the digital twin that best matches the patient. Economic analysis will evaluate benefits arising from early preventative and longer-lasting treatment, reduced duration and procedural risks of interventions." }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-09-28T02:00:00+02:00", "assignment": "2023-02-01T16:15:05+01:00", "program": 112, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 50966, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I 6476-B", "ethics_committee": null, "edudract_number": null, "persons": [ "7363-50966-10", "7363-91352-12", "7363-96212-12", "7363-50967-12", "7363-122514-12" ] } ] }