Project List
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GET /v1/research/project/?format=api&offset=1820&ordering=begin_effective
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1840&ordering=begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1800&ordering=begin_effective", "results": [ { "id": 7272, "title": { "de": "Die Rolle von Epigenetik und veränderter Zytokinantwort in Stimmlippen-Fibroblasten von Reinke Ödem Patienten", "en": "Role of epigenetics and differential cytokine response in vocal fold fibroblasts of Reinke's edema patients" }, "short": "RE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-08-01T02:00:00+02:00", "begin_effective": "2023-01-16T01:00:00+01:00", "end_planned": "2025-07-31T02:00:00+02:00", "end_effective": "2027-01-15T01:00:00+01:00", "assignment": "2022-11-29T15:14:56+01:00", "program": 72, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 69755, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P36067", "ethics_committee": null, "edudract_number": null, "persons": [ "7272-50670-12", "7272-50698-12", "7272-50899-12", "7272-69755-10", "7272-77116-12", "7272-82902-12", "7272-97517-12", "7272-98190-12", "7272-88652-12", "7272-103118-12", "7272-129518-12" ] }, { "id": 7456, "title": { "de": "VON DER BIOINFORMATISCHEN ANALYSE VON GENOMEN BIS ZUR COMPUTERGESTÜTZTEN STRUKTURBIOLOGIE UND ANWENDUNGEN", "en": "FROM BIOINFORMATICS ANALYSIS OF GENOMES TO COMPUTATIONAL STRUCTURAL BIOLOGY AND APPLICATIONS" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-02-01T01:00:00+01:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2023-11-30T01:00:00+01:00", "end_effective": "2023-11-30T01:00:00+01:00", "assignment": "2023-03-23T16:19:40+01:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 2, "manager": 107189, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1287 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7456-107189-10" ] }, { "id": 7130, "title": { "de": "Profiling und funktionelle Analyse des Immun-Environments des extramedullären Leukämierelapses\r\n\r\n", "en": "Profiling and functional analysis of the Immune environment of eXtramedullary leukemia rELapses\r\n\r\n" }, "short": "PIXEL", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-07-01T02:00:00+02:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2025-07-01T02:00:00+02:00", "end_effective": "2026-04-30T02:00:00+02:00", "assignment": "2022-08-16T10:27:51+02:00", "program": 112, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 1, "manager": 57402, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I6101", "ethics_committee": null, "edudract_number": null, "persons": [ "7130-57402-10", "7130-97430-12", "7130-118869-12" ] }, { "id": 7415, "title": { "de": "Magnetischer Stein", "en": "Magnetic Stone" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2023-02-23T09:38:55+01:00", "program": null, "subprogram": null, "organization": 14012, "category": 10, "type": 10, "partner_function": 4, "manager": 113130, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-87", "ethics_committee": null, "edudract_number": null, "persons": [ "7415-113130-10" ] }, { "id": 7297, "title": { "de": "MICRObiome Biobanking (RI) Enabler", "en": "MICRObiome Biobanking (RI) Enabler" }, "short": "MICROBE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-02-01T01:00:00+01:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2027-01-31T01:00:00+01:00", "end_effective": "2027-01-31T01:00:00+01:00", "assignment": "2022-12-07T11:19:47+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "101094353", "ethics_committee": null, "edudract_number": null, "persons": [ "7297-51870-12", "7297-51663-10" ] }, { "id": 8242, "title": { "de": "Aktivierte Eosinophile als Schlüsselfiguren im Dickdarmkrebs", "en": "Activated eosinophils as key players in colon cancer development" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-02-01T01:00:00+01:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2024-01-31T01:00:00+01:00", "end_effective": "2024-01-31T01:00:00+01:00", "assignment": "2024-06-10T11:06:25+02:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 99558, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894, 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8242-99558-10" ] }, { "id": 7385, "title": { "de": "Benützung automatisierter Insulindosierungssysteme während eines kommerziellen Linienflugs - Eine Pilotstudie ", "en": "The Use of the Automated Insulin Delivery Systems During a\r\nCommercial Airplane Flight - a PILOT Study \r\n" }, "short": "AID_PILOT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-02-01T01:00:00+01:00", "begin_effective": "2023-02-01T01:00:00+01:00", "end_planned": "2023-12-01T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2023-02-09T10:40:04+01:00", "program": null, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 4, "manager": 100301, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 151 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7385-100301-10" ] }, { "id": 7239, "title": { "de": "T3-induzierte mitochondriale Ca2+ Veränderung in Krebszellen", "en": "T3-induced rewiring of mitochondrial Ca2+ in cancer cells" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-10-01T02:00:00+02:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2025-09-30T02:00:00+02:00", "end_effective": "2026-05-31T02:00:00+02:00", "assignment": "2022-10-31T13:31:29+01:00", "program": 72, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 85069, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P36235", "ethics_committee": null, "edudract_number": null, "persons": [ "7239-85069-10" ] }, { "id": 7427, "title": { "de": "Morphologische und molekulare Charakterisierung von Sarkomen mit EWSR1/FUS::CREB3L1/2 Fusionen ", "en": "Morphological characterization and molecular profiling of a spectrum of\r\nEWSR1/FUS::CREB3L1/2 rearranged sarcomas\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2024-03-01T01:00:00+01:00", "end_effective": "2024-03-31T01:00:00+01:00", "assignment": "2023-03-03T12:00:08+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 92422, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-90", "ethics_committee": null, "edudract_number": null, "persons": [ "7427-92422-10" ] }, { "id": 8315, "title": { "de": "Der Effekt von therapeutischen ACE2-Fc Fusionsproteinen auf SARS-CoV-2 exponierte Makrophagen", "en": "The effect of therapeutic ACE2-Fc fusion proteins on\r\nmacrophages exposed to SARS-CoV-2" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2026-02-28T01:00:00+01:00", "end_effective": "2026-02-28T01:00:00+01:00", "assignment": "2024-07-29T10:49:51+02:00", "program": null, "subprogram": null, "organization": 29164, "category": 10, "type": 10, "partner_function": 4, "manager": 99430, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8315-99430-10" ] }, { "id": 7468, "title": { "de": "SFB Lipidhydrolyse: Zusatzfinanzierung Land Steiermark (Förderperiode 2)", "en": "SFB Lipidhydrolyse: add-on Land Steiermark (funding periode 2)" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2027-02-28T01:00:00+01:00", "end_effective": "2027-02-28T01:00:00+01:00", "assignment": "2023-04-05T15:19:16+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 3, "manager": 51904, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7468-51904-10" ] }, { "id": 7363, "title": { "de": "Digitale Zwillinge für die Behandlung von Vorhofflimmern", "en": "Digital Twins to Treat Atrial Fibrillation" }, "short": "DAWN-AF", "url": null, "abstract": { "de": "Vorhofflimmern (VHF) ist die häufigste Arrhythmie des Herzens. Bei VHF handelt es sich um eine fortschreitende Erkrankung des Herzens. Je länger VHF andauert, umso schwieriger ist die Behandlung, und das Risiko Folgeschäden wie Schlaganfälle, Demenz oder Herzinsuffizienz zu erleiden nimmt zu. Die effektivste Therapie für VHF ist die Ablationstherapie mittels Herzkatheter, eine Prozedur, bei der Gewebe in den Vorhöfen des Herzens zerstört wird um die Ausbreitungspfade von elektrischen Wellen einzuschränken. Aktuelle Therapieformen sind generisch, die Variabilität der Patienten hinsichtlich der Struktur der Vorhöfe wird nicht berücksichtigt, weshalb VHF-Symptome auch nach anfänglich positiver Therapie häufig zurückkehren.\r\n\r\nDas Ziel des DAWN-AF Projektes ist es, einen personalisierten medizinischen Ansatz zu entwickeln, der auf Computermodellierung basiert. Konkret werden digitale Zwillinge der Vorhöfe des Herzens entwickelt. Diese können zur verbesserten Planung der VHF-Ablation im Computer verwendet werden, um ein Wiederauftreten von VHF zu verhindern. Dazu werden präoperative Messungen wie das Elektrokardiogramm und tomographische Bildgebung (MRT/CT) verwendet, um anatomisch und funktionell detaillierte digitale Zwillinge zu erstellen. Da diese Daten jedoch nicht ausreichen, um die Vorhöfe eindeutig zu charakterisieren, wird für jeden Patienten ein Satz an potenziellen digitalen Zwillingen erstellt, um dann für jede einzelne Variation die jeweils ideale Ablationsbehandlung zu bestimmen. Anhand von invasiven Messungen während des Eingriffs wird dann derjenige digitale Zwilling ausgewählt, der am besten zum Patienten passt. Eine wirtschaftliche Analyse der VHF-Therapie wird den Nutzen unseres mittels digitaler Zwillinge personalisierten Therapiezugangs bewerten. Dieser Nutzen ergibt sich aus einer frühzeitigen präventiven Behandlung, aus einem länger anhaltenden Therapieerfolg, aus einer verkürzten Eingriffsdauer und einer Reduktion des Eingriffsrisikos.\r\n", "en": "Atrial Fibrillation (AF) is the most common cardiac arrhythmia. Since AF is progressive, the longer one has it, the harder it is to treat, and the risks of stroke, dementia and heart failure increase. The most effective treatment is catheter ablation therapy, a procedure that strategically destroys tissue to restrict propagation of electrical waves. However, approaches are currently generic, ignoring patient variability in atrial structure, and AF usually recurs. We aim to develop a personalised medicine approach based on computer modelling, to use digital twins to plan AF ablation to prevent recurrence. We propose to use preoperative measurements, imaging (MRI/CT) and the ECG, to build digital twins. However, these data are insufficient to uniquely characterize the atria, so we will build sets of potential digital twins for each patient, each of which will have its ideal ablation treatment determined. Invasive measurements acquired during the ablation procedure will be then used to select the digital twin that best matches the patient. Economic analysis will evaluate benefits arising from early preventative and longer-lasting treatment, reduced duration and procedural risks of interventions." }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-09-28T02:00:00+02:00", "assignment": "2023-02-01T16:15:05+01:00", "program": 112, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 50966, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I 6476-B", "ethics_committee": null, "edudract_number": null, "persons": [ "7363-50966-10", "7363-91352-12", "7363-96212-12", "7363-50967-12", "7363-122514-12" ] }, { "id": 7247, "title": { "de": "Therapeutische Ansätze für die Regulation von Mitochondrien und Autophagie bei Herzinsuffizienz", "en": "Targeting mitochondria-autophagy circuits in heart failure" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2027-02-28T01:00:00+01:00", "end_effective": "2027-02-28T01:00:00+01:00", "assignment": "2022-11-10T12:19:42+01:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 94512, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2325 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7247-94512-10", "7247-94653-12", "7247-119110-12", "7247-119113-12", "7247-129380-12" ] }, { "id": 7551, "title": { "de": "SFB Lipidhydrolyse - Zusatzförderung Stadt Graz (2. Förderperiode)", "en": "SFB Lipidhydrolysis - add-on Stadt Graz (2. funding periode)" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2024-02-28T01:00:00+01:00", "end_effective": "2025-02-28T01:00:00+01:00", "assignment": "2023-05-09T16:21:34+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 3, "manager": 51904, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7551-51904-10" ] }, { "id": 7344, "title": { "de": "SFB Lipidydrolyse (Koordination): Zelluläre Lipidabbauwege in Gesundheit und Krankheit (Koordinationsprojekt) - 2. Förderperiode", "en": "SFB Lipid Hydrolysis (coordination): Cellular lipid degradation pathways in health and disease (Coordination Project) - 2. funding periode" }, "short": "SFB Lipid Hydrolysis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2027-02-28T01:00:00+01:00", "end_effective": "2027-02-28T01:00:00+01:00", "assignment": "2023-01-23T12:02:41+01:00", "program": 67, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 3, "manager": 51904, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "F 73", "ethics_committee": null, "edudract_number": null, "persons": [ "7344-76131-12", "7344-51904-10", "7344-103617-12", "7344-107151-12", "7344-107153-12", "7344-102005-12", "7344-121750-12", "7344-133941-12", "7344-135873-12", "7344-122612-12", "7344-122630-12" ] }, { "id": 7339, "title": { "de": "Targeting der zellulären Seneszenz basierend auf inter-organellarer Kommunikation, Proteostasis und metabolischer Kontrolle", "en": "Targeting cellular senescence based on inter-organelle communication, multi-level proteostasis and metabolic control " }, "short": "SenioProm", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2027-02-28T01:00:00+01:00", "end_effective": "2026-08-31T02:00:00+02:00", "assignment": "2023-01-18T15:33:07+01:00", "program": 113, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 2, "manager": 85069, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "FG 2400-B", "ethics_committee": null, "edudract_number": null, "persons": [ "7339-85069-10" ] }, { "id": 7309, "title": { "de": "Bewertung der Rolle der Succinat-Sensierung über GPR91 bei der T-Zell-vermittelten Anti-Tumor-Immunität ", "en": "Evaluating the role of succinate sensing via GPR91 in T cell-mediated \r\nanti-tumour immunity " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-01-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2026-09-30T02:00:00+02:00", "assignment": "2022-12-20T13:44:44+01:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": 107391, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2576 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7309-60706-12", "7309-107391-10" ] }, { "id": 7437, "title": { "de": "Evaluierung von protektiven molekularen Mechanismen einer ketogenen Diät in der experimentellen Glomerulonephritis", "en": "INVESTIGATION OF PROTECTIVE MOLECULAR MECHANISMS OF A KETOGENIC DIET IN EXPERIMENTAL GLOMERULONEPHRITIS" }, "short": "Mechanismen ketogene Diät", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2024-02-27T01:00:00+01:00", "end_effective": "2024-12-31T01:00:00+01:00", "assignment": "2023-03-08T15:38:26+01:00", "program": null, "subprogram": null, "organization": 14084, "category": 10, "type": 10, "partner_function": 4, "manager": 74174, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-85", "ethics_committee": null, "edudract_number": null, "persons": [ "7437-74174-10" ] }, { "id": 7407, "title": { "de": "Bioorthogonal Implantable Iontronic Switch to Temporally Control the Local Release of Chemotherapeutics", "en": "Bioorthogonal Implantable Iontronic Switch to Temporally Control the Local Release of Chemotherapeutics" }, "short": "bioSWITCH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2022-12-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2027-02-28T01:00:00+01:00", "assignment": "2023-02-17T11:53:05+01:00", "program": 218, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 98848, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "101099963", "ethics_committee": null, "edudract_number": null, "persons": [ "7407-99703-11", "7407-57129-12", "7407-98848-10", "7407-107229-12", "7407-114534-12", "7407-119850-12", "7407-122232-12" ] }, { "id": 7431, "title": { "de": "Mikrobieller Fingerabdruck von Flüssigbiopsien", "en": "Microbial fingerprint of liquid biopsies" }, "short": "MFLB", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2023-03-01T01:00:00+01:00", "begin_effective": "2023-03-01T01:00:00+01:00", "end_planned": "2025-02-28T01:00:00+01:00", "end_effective": "2026-02-28T01:00:00+01:00", "assignment": "2023-03-06T09:47:38+01:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": 100035, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "7431-76215-11", "7431-100035-10", "7431-113714-12" ] } ] }