Project List
List projects.
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GET /v1/research/project/?format=api&offset=1740&ordering=-end_planned
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1760&ordering=-end_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1720&ordering=-end_planned", "results": [ { "id": 2566, "title": { "de": "Der Einfluß von hämodynamischen Parametern auf die zerebrale Oxygenierung bei Frühgeborenen mit und ohne arterieller Hypotonie während des ersten Lebenstages. ", "en": "Influence of hemodynamic parameters on cerebral oxygention in preterm neonates with and without hypotonia during the first day of life. " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-09-01T02:00:00+02:00", "begin_effective": "2011-09-01T02:00:00+02:00", "end_planned": "2014-03-30T01:00:00+01:00", "end_effective": "2014-03-30T01:00:00+01:00", "assignment": "2011-09-05T12:37:39+02:00", "program": null, "subprogram": "Initiative für Früh- und Neugeborene", "organization": 14094, "category": 10, "type": 10, "partner_function": null, "manager": 50907, "contact": 59859, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2566-50907-10" ] }, { "id": 2664, "title": { "de": "Der Einfluß von hämodynamischen Parametern auf die zerebrale Oxygenierung bei Frühgeborenen mit und ohne arterieller Hypotonie während des ersten Lebenstages.", "en": "Influence of hemodynamic parameters on cerebral oxygention in preterm neonates with and without hypotonia during the first day of life." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-09-01T02:00:00+02:00", "begin_effective": "2012-01-01T01:00:00+01:00", "end_planned": "2014-03-30T01:00:00+01:00", "end_effective": "2012-12-31T01:00:00+01:00", "assignment": "2011-12-12T11:07:59+01:00", "program": null, "subprogram": "Stadt Graz - Kulturamt-Wissenschaft", "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": 50907, "contact": 50907, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2664-50907-10" ] }, { "id": 3207, "title": { "de": "Klumpfußbehandlung für Kinder in Mali mit der Ponseti-Methode", "en": "Treating Paediatric Clubfeet in Mali with the Ponseti Mathod" }, "short": "Mali", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-01T01:00:00+01:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2014-03-01T01:00:00+01:00", "end_effective": "2016-03-31T02:00:00+02:00", "assignment": "2013-03-12T11:07:57+01:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 54144, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3207-54144-10" ] }, { "id": 5498, "title": { "de": "Anti-atherogene Wirkung neuer Paraoxonase Substrate ", "en": "Athero-protective effects of novel paraoxonase\r\nsubstrates" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-01T01:00:00+01:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2014-02-28T01:00:00+01:00", "end_effective": "2014-03-31T02:00:00+02:00", "assignment": "2018-09-26T15:18:52+02:00", "program": null, "subprogram": "MUG-Start-Förderung", "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 62749, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5498-62749-10" ] }, { "id": 3504, "title": { "de": "Infrastrukturförderung zur Etablierung des BBMRI-ERIC Sitzes", "en": "infrastructure grant to establish the office of BBMRI-ERIC" }, "short": "BBMRI-ERIC Office", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2014-02-28T01:00:00+01:00", "end_effective": "2014-02-28T01:00:00+01:00", "assignment": "2014-01-16T14:45:31+01:00", "program": 90, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51663, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 25 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3504-51663-10" ] }, { "id": 3091, "title": { "de": "Hierarchische poröse Sensorsysteme zur in-vivo Detektion von Änderungen des physiologischen Umgebungsmilieus in der Humanmedizin", "en": "Hierarchic poriferous sensor systems for invivo detection of changes of the physiological environment in human medicin" }, "short": "PhysioNanoAkt", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-09-01T02:00:00+02:00", "begin_effective": "2012-09-01T02:00:00+02:00", "end_planned": "2014-02-28T01:00:00+01:00", "end_effective": "2014-02-28T01:00:00+01:00", "assignment": "2012-12-06T10:30:29+01:00", "program": null, "subprogram": "HTI", "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3854, "title": { "de": "Die Prävalenz von FHH bei PatientInnen mit einem primären Hyperparathyreoidismus", "en": "The Prevalence of FHH in Patients with Primary Hyperparathyroidism" }, "short": "EPATH-FHH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-07-01T02:00:00+02:00", "begin_effective": "2015-02-01T01:00:00+01:00", "end_planned": "2014-02-01T01:00:00+01:00", "end_effective": "2019-01-31T01:00:00+01:00", "assignment": "2015-01-13T10:13:03+01:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 81519, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1565 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3854-81519-10" ] }, { "id": 3159, "title": { "de": "Assoziation von Biomarkern des Knochen- und Nierenstoffwechsels mit der kardiovaskulären Mortalität", "en": "Association of biomarkers of kidney, bone and vitamin D metabolism with cardiovascular mortality " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2014-01-31T01:00:00+01:00", "end_effective": "2014-01-31T01:00:00+01:00", "assignment": "2013-01-29T09:41:32+01:00", "program": 79, "subprogram": null, "organization": 14028, "category": 10, "type": 10, "partner_function": 4, "manager": 50886, "contact": 50886, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3159-50886-10" ] }, { "id": 2525, "title": { "de": "Genetische Typisierung von Klebsiella oxytoca Stämmen in Bezug auf deren Fähigkeit zur Toxinproduktion und Assoziation zur Entstehung von Colitis.", "en": "Typing of Klebsiella oxytoca Strains Concerning to their Ability for Toxin-Production and their Association to the Develoment of Colitis." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-07-01T02:00:00+02:00", "begin_effective": "2011-07-01T02:00:00+02:00", "end_planned": "2014-01-01T01:00:00+01:00", "end_effective": "2014-10-31T01:00:00+01:00", "assignment": "2011-07-12T16:25:15+02:00", "program": 79, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 53167, "contact": 53167, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2525-53167-10" ] }, { "id": 3197, "title": { "de": "Antibiotika-assoziierte hämorrhagische Kolitis ausgelöst durch Klebsiella oxytoca bei Kindern", "en": "Antibiotic-associated hemorrhagic colitis (AAHC) caused by Klebsiella oxytoca in children and adolescents" }, "short": "AAHC bei Kindern", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2014-01-01T01:00:00+01:00", "end_effective": "2016-02-28T01:00:00+01:00", "assignment": "2013-03-01T09:57:45+01:00", "program": null, "subprogram": null, "organization": 14091, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4136, "title": { "de": "\"Chordome - Erforschung neuer therapeutischer Targets\"", "en": "“Chordomas – Studying Possible Therapeutic Targets”" }, "short": "Chordom HDAC", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2013-12-31T01:00:00+01:00", "assignment": "2015-11-02T09:51:00+01:00", "program": 92, "subprogram": "Marietta Blau-Stipendium", "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": 50448, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4136-50448-10" ] }, { "id": 2154, "title": { "de": "Contribution of cell-cell contacts and cross-talk to cell conversion into cardiomyocytes ", "en": "Contribution of cell-cell contacts and cross-talk to cell conversion into cardiomyocytes " }, "short": "CARDIOMYOCYTES", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-01-01T01:00:00+01:00", "begin_effective": "2011-02-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-01-31T01:00:00+01:00", "assignment": "2010-03-04T15:03:51+01:00", "program": 72, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P22466", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3289, "title": { "de": "Hepcidin als diagnostischer Marker der Appendicitis im Kindesalter", "en": "Hepcidin as a diagnositic tool of appendicits in childhood" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2013-05-23T15:41:16+02:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 50778, "contact": 50778, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3289-50778-10" ] }, { "id": 3226, "title": { "de": "Von Hypertrophie zur Herzinsuffizienz-die Rolle des spontanen SR Ca2+ Lecks", "en": "From hypertrophy to heart failure-the role of spontaneous SR Ca2+ leak" }, "short": "MUG Start", "url": null, "abstract": { "de": null, "en": "Heart failure (HF) is a leading cause of death in the developed countries. Despite considerable progress in the past decade in our understanding of cellular and molecular mechanisms involved in the progression of HF, therapeutic agents that specifically target the underlying cellular defects remain rare and ineffective. In HF, intracellular Ca2+ homeostasis is altered and increased cytosolic Ca2+ has been proposed as a potential activator of hypertrophic signalling cascades, ultimately culminating in overt HF phenotype. Recent studies pointed out that increased spontaneous Ca2+ release (Ca2+ leak) from the sarcoplasmic reticulum (SR) Ca2+ release channel (ryanodine receptor, RyR2) due to defective regulation of the RyR2 occurs during HF and causes contractile dysfunction and development of arrhythmias. However, it remains controversial whether increased SR Ca2+ leak is an epiphenomenon accompanying HF only or a pathophysiologically relevant process contributing to accelerated decompensation from hypertrophy to HF.\r\nIn the proposed project, we will pursue the hypothesis, that an increased spontaneous SR Ca2+ leak per se is causally involved in accelerated decompensation from cardiac hypertrophy to HF. We will take advantage of the minimally invasive transverse aortic constriction (TAC) as a pressure overload model for HF, and apply it to a mouse model with an inherited SR Ca2+ leak (knock-in RyR2R4496C+/- human mutation). Our preliminary results show strikingly increased hypertrophy and accelerated transition from hypertrophy to HF in RyR2R4496C+/- hearts after TAC, confirming our initial hypothesis. In the current project, we aim to identify the mechanism(s) of the transition from hypertrophy to overt HF. We will investigate, whether congenital SR Ca2+ leak in RyR2R4496C+/- cardiomyocytes is increased after TAC and, subsequently, leads to alterations in expression and/or phosphorylation pattern of Ca2+ regulatory proteins and transcription factors involved in Ca2+-dependent hypertrophic signalling pathways. Using in vivo ECG recordings, we will further determine the cause for premature cardiac death in RyR2R4496C+/--TAC mice. Additionally, rescue experiments will reveal, whether a putative RyR2 stabilizer (JTV-519) effectively decelerates the HF progression. \r\nWe anticipate that these results will help to define a new role for SR Ca2+ release in the transition from cardiac hypertrophy to HF. Since abnormal RyR2 Ca2+ release is regarded as the underlying mechanism for contractile dysfunction and arrhythmias, this project may contribute to the identification of novel molecular therapeutic targets in HF and thus, possibly improve clinical outcome in HF patients in the future.\r\n" }, "begin_planned": "2011-01-01T01:00:00+01:00", "begin_effective": "2011-01-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2013-12-31T01:00:00+01:00", "assignment": "2013-04-02T15:52:03+02:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 60041, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3226-60041-10" ] }, { "id": 3230, "title": { "de": "Eye-Tracking mit 500Hz vs. 1250Hz: Höhere Abtastrate, neue Erkenntnisse...", "en": "Eye tracking with 500Hz vs. 1250Hz: Higher sampling rate, new findings¿" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-03-30T01:00:00+01:00", "assignment": "2013-04-11T10:33:06+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 77049, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3230-77049-10" ] }, { "id": 2626, "title": { "de": "Identifizierung neuer genetischer Ursachen für familiäres Primäres Offenwinkelglaukom (POWG) mittels Komplett-Exom-Sequenzierung", "en": "Identification of novel genes associated with familial Primary Open Angle Glaucoma by use of Whole-Exome-Sequencing" }, "short": "Genetik POWG", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-08-16T02:00:00+02:00", "begin_effective": "2011-08-16T02:00:00+02:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2013-12-31T01:00:00+01:00", "assignment": "2011-11-07T09:56:07+01:00", "program": null, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2293, "title": { "de": "Die pulmonale Mikrozirkulation bei Sepsis und Adipositas", "en": "Pulmonary Microcirculation during Sepsis and Obesity The Role of Cytokines and Adhesion Molecules" }, "short": "PULMONALE MIKROZIRK SEPSIS ADIPOS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-01-01T01:00:00+01:00", "begin_effective": "2010-11-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2015-10-31T01:00:00+01:00", "assignment": "2010-09-07T13:56:50+02:00", "program": 72, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 50778, "contact": 50778, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P22567", "ethics_committee": null, "edudract_number": null, "persons": [ "2293-50778-10" ] }, { "id": 2546, "title": { "de": "MSc in Migrant Health: Adressing New Challenges in Europe", "en": "MSc in Migrant Health: Adressing New Challenges in Europe" }, "short": "MSC IN MIGRANT HEALTH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-01-01T01:00:00+01:00", "begin_effective": "2010-10-01T02:00:00+02:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2013-09-30T02:00:00+02:00", "assignment": "2011-07-28T12:19:44+02:00", "program": null, "subprogram": "Erasmus", "organization": 29447, "category": 10, "type": 10, "partner_function": 2, "manager": 51521, "contact": 51521, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2546-51521-10" ] }, { "id": 2146, "title": { "de": "AP@home", "en": "AP@home" }, "short": "AP@home", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-10-01T02:00:00+02:00", "begin_effective": "2010-02-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-10-31T01:00:00+01:00", "assignment": "2010-03-02T11:22:16+01:00", "program": 24, "subprogram": "ICT: FP7-ICT-2009-4", "organization": 14080, "category": 10, "type": 10, "partner_function": 2, "manager": 51831, "contact": 51831, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2146-51831-10", "2146-50877-12", "2146-61759-12", "2146-56674-12", "2146-50731-12" ] }, { "id": 3047, "title": { "de": "Bild- und Tiefeninformation zur automatischen Lagekorrektur von Patienten in medizinischen Geräten", "en": "Bild- und Tiefeninformation zur automatischen Lagekorrektur von Patienten in medizinischen Geräten" }, "short": "BTAL", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-05-01T02:00:00+02:00", "begin_effective": "2012-05-01T02:00:00+02:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2012-11-21T14:39:21+01:00", "program": null, "subprogram": "HTI-Call 2012", "organization": 14043, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] } ] }