Project List
List projects.
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GET /v1/research/project/?format=api&offset=1680&ordering=-end_planned
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1700&ordering=-end_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1660&ordering=-end_planned", "results": [ { "id": 2954, "title": { "de": "Genetik von Patienten_innen mit Fuchsscher Endotheldystrophie in einer österreichischen Population", "en": "Genetic investigation of Fuchs' endothelial corneal dystrophy in an Austrian population" }, "short": "Genetik bei Fuchsscher Endotheldystroph", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-11-01T01:00:00+01:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-11-01T01:00:00+01:00", "end_effective": "2015-09-20T02:00:00+02:00", "assignment": "2012-08-29T10:24:13+02:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 4, "manager": 65638, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135, 938 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2954-65638-10" ] }, { "id": 3581, "title": { "de": "Kortikale Pathologie und periventrikuläre Läsionen bei Multipler Sklerose – Ausdruck identer pathophysiologischer Prozesse?", "en": "An MRI-study to investigate the pathophysiological link between cortical atrophy and periventricular lesions in multiple sclerosis" }, "short": "MS-KORTEX", "url": null, "abstract": { "de": "Die Pathogenese kortikaler Läsionen sowie der Zusammenhang der verschiedenen degenerativen Prozesse im ZNS bei MS sind bis heute weitgehend unklar. Bisherige Studien zeigten, dass meningeale Entzündungen eine wichtige Rolle bei der Entstehung der kortikalen Pathologie spielen können. Aggregierte Lymphozyten und Antikörper (T- und B- Zellen) infiltrieren Meningen und perivaskuläre Bereiche und führen in weiterer Folge zu einer Progression der Erkrankung. Aus dieser Erkenntnis ergibt sich die Fragestellung, ob unmittelbar periventrikuläre (d.h. liquornahe) Marklagerläsionen mit der kortikalen Pathologie in MS in Zusammenhang stehen.Um diese Fragestellung zu untersuchen, sollen in einem interdisziplinären Forschungsprojekt der Universitätsklinik für Neurologie und der klinischen Abteilung für Neuroradiologie (Universitätsklinik für Radiologie) der Medizinischen Universität Graz existierende MRT-Daten einer unizentrischen prospektiven MS-Studie (n=170) analysiert werden. Die kortikale Pathologie wird anhand der Messung der kortikalen Dicke geschätzt. Periventrikuläre Läsionen der weißen Substanz werden halbautomatisiert segmentiert. Die MR-Parameter werden quantifiziert und mittels Korrelationsanalyse wird die Hypothese überprüft, ob verminderte kortikale Dicke (sogenanntes „cortical thinning“ als Ausdruck subpialer kortikaler Läsionen) mit einer Häufung periventrikulärer Läsionen korreliert. Eine Korrelation zwischen diesen MR-Parametern wäre möglicherweise ein Hinweis dafür, dass die Läsionsprogression in MS durch spezifische Faktoren in der zerebrospinalen Flüssigkeit beschleunigt beziehungsweise vielleicht sogar initiiert wird.", "en": null }, "begin_planned": "2014-05-01T02:00:00+02:00", "begin_effective": "2014-03-01T01:00:00+01:00", "end_planned": "2014-11-01T01:00:00+01:00", "end_effective": "2015-08-31T02:00:00+02:00", "assignment": "2014-02-27T11:39:15+01:00", "program": null, "subprogram": null, "organization": 14108, "category": 10, "type": 10, "partner_function": 4, "manager": 60744, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3581-60744-10", "3581-51882-11", "3581-50173-11" ] }, { "id": 2939, "title": { "de": "Untersuchungen zu den Effekten eines Trainings von Gang und Gleichgewicht auf Gehirnfunktion im Alter - Einblicke anhand der funktionellen Magnetresonanztomographie (fMRT)", "en": "Investigations into the effects of gait and coordinative training on cerebral function in ageing - insights from functional MRI (fMRI)" }, "short": "Training the Brain", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-10-01T02:00:00+02:00", "begin_effective": "2012-08-01T02:00:00+02:00", "end_planned": "2014-10-01T02:00:00+02:00", "end_effective": "2015-02-28T01:00:00+01:00", "assignment": "2012-07-26T17:29:17+02:00", "program": null, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 50173, "contact": 50173, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2939-50173-10" ] }, { "id": 3492, "title": { "de": "Funktionelle Analyse eines neuen familiären kolorektalen Krebssyndrom X Prädispositionsgens", "en": "Functional Analysis of a Novel Familial Colorectal Cancer Type X Predisposition Gene" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2013-12-01T01:00:00+01:00", "end_planned": "2014-10-01T02:00:00+02:00", "end_effective": "2015-01-31T01:00:00+01:00", "assignment": "2014-01-09T11:59:23+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 77615, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1519 ], "funder_projectcode": "MEFO-01", "ethics_committee": null, "edudract_number": null, "persons": [ "3492-77615-10" ] }, { "id": 3131, "title": { "de": "Schwangerschaftserkrankungen-Die Rolle von Metalloproteinasen und Endothelin", "en": "Pregnancy diseases - The role of metalloproteinases and endothelin" }, "short": "Schwangerschaftserkrankungen", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2013-01-07T16:00:05+01:00", "program": 79, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2989, "title": { "de": "Einfluss von Leoligin, einem Inhaltsstoff des Edelweiss, auf den HDL-Cholesterin Stoffwechsel", "en": "Impact of leoligin, a major lignan from Edelweiss, on HDL-cholesterol metabolism" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-02-28T01:00:00+01:00", "assignment": "2012-10-01T17:43:51+02:00", "program": null, "subprogram": "Joseph Skoda-Projektförderungspreis der ÖGIM ", "organization": 14079, "category": 10, "type": 10, "partner_function": 4, "manager": 74175, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 204 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2989-74175-10" ] }, { "id": 2962, "title": { "de": "Kupfer Resistenzmechanismen in multiresistenten Bakterien", "en": "Mechanisms of copper resistance in multiresistant bacteria" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-02-28T01:00:00+01:00", "assignment": "2012-09-03T16:36:06+02:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": 54018, "contact": 54018, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 895 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2962-54018-10", "2962-58733-12", "2962-65782-12" ] }, { "id": 3782, "title": { "de": "Mitochondrien als neues Ziel in der Behandlung diverser Erkrankungen", "en": "Mitochondria- a novel target for treatment of many diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-01T01:00:00+01:00", "begin_effective": "2014-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-09-30T02:00:00+02:00", "assignment": "2014-10-07T15:55:58+02:00", "program": null, "subprogram": null, "organization": 28392, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2615, "title": { "de": "Tailored biodegradable magnesium implant materials", "en": "Tailored biodegradable magnesium implant materials" }, "short": "MagnIM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-10-01T02:00:00+02:00", "begin_effective": "2011-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-09-30T02:00:00+02:00", "assignment": "2011-10-18T11:42:58+02:00", "program": 24, "subprogram": "Marie Curie Initial Training Network (ITN)", "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": 50785, "contact": 50785, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "289163", "ethics_committee": null, "edudract_number": null, "persons": [ "2615-50785-10" ] }, { "id": 3309, "title": { "de": "Biomarker ErKennenLernen, Projektnr: 839728", "en": "Biomarker ErKennenLernen" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-10-01T02:00:00+02:00", "begin_effective": "2013-08-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2014-07-31T02:00:00+02:00", "assignment": "2013-06-21T10:07:47+02:00", "program": null, "subprogram": null, "organization": 28394, "category": 10, "type": 10, "partner_function": 2, "manager": 58453, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "839728 ", "ethics_committee": null, "edudract_number": null, "persons": [ "3309-58453-10" ] }, { "id": 2911, "title": { "de": "Psoriasis, dysfunktionales HDL und koronare Herzkrankheit ", "en": "Psoriasis, dysfunctional HDL und coronary artery disease" }, "short": "Psoriasis verände3rt gutes Cholesterin", "url": null, "abstract": { "de": "Psoriasis, dysfunktionales HDL und koronare Herzkrankheit \r\n\r\nPsorias, eine chronisch entzündliche Hautererkrankung, betrifft etwa 3% der Menschen weltweit. Psoriasis ist ein eigenständiger erheblicher Risikofaktor für arterielle Erkrankungen des Herz-Kreislauf-Systems, die Ursachen für den beobachteten Zusammenhang sind jedoch unklar. In diesem Projektantrag soll untersucht werden, ob Psoriasis mit einer funktionellen Beeinträchtigung des high-density lipoproteins (HDL) assoziiert ist. Unter physiologischen Bedingungen vermittelt anti-atherogenes HDL den reversen Cholesterintransport und wirkt vaskuloprotektiv. Mittels massenspektroskopischen und biochemischen Analysen sollen Veränderungen im Proteom und in der Lipidzusammensetzung des HDL von Psoriasis Patienten im Vergleich zu gesunden Kontrollen untersucht werden. In weiterer Folge soll untersucht werden, ob eine veränderte HDL-Zusammensetzung mit einer funktionellen Beeinträchtigung des HDL-Partikels einhergeht. \r\n", "en": "Psoriasis, a very common skin disease, is nowadays considered as a systemic inflammatory condition. Psoriasis patients harbor an increased risk of myocardial infarction and stroke, and numerous studies indicate that psoriasis and cardiovascular disease - particularly atherosclerosis - share common pathogenic features. \r\nPatients with autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis have decreased levels of high-density lipoprotein (HDL), suggesting that HDL may be important in preventing autoimmunity and the loss of self-tolerance. Proposed mechanisms for the atheroprotective functions of HDL include reverse cholesterol transport, reduction of oxidative stress and potent anti-inflammatory effects. On the other hand, HDL was shown to lose its-anti-atherogenic properties by post-translational modifications such as oxidation and carbamylation. There is emerging evidence suggesting that anti-atherogenic activities of HDL cannot be described by its plasma concentrations alone. For example, cholesterol efflux capacity, a functional measure of HDL, has an inverse association with the likelihood of coronary artery disease independent of HDL-cholesterol levels. Recent studies that elucidated the proteome of HDL from healthy individuals and patients with coronary artery disease or renal disease by mass spectrometry revealed that the protein cargo is a major determinant of the anti-atherogenic and anti-inflammatory properties of HDL. As qualitative alterations of HDL seem to be directly linked with increased cardiovascular complications, we hypothesize that HDL from psoriatic patients might display defective cholesterol efflux capability and anti-oxidative activities. \r\n" }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-09-30T02:00:00+02:00", "assignment": "2012-07-06T12:57:50+02:00", "program": 79, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 53252, "contact": 53252, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2911-53252-10" ] }, { "id": 2980, "title": { "de": "Gewebedatenbank zur Erforschung der stadienabhängigen Herzinsuffizienz Graz", "en": "Tissue database Graz for the investigation of stage-dependent heart failure" }, "short": "GESHG", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2013-09-30T02:00:00+02:00", "assignment": "2012-09-20T11:36:28+02:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 59941, "contact": 59941, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2980-59941-10" ] }, { "id": 3116, "title": { "de": "Qualifizierungsnetz Humantechnologie Projekt Nr. 836248", "en": "Qualifizierungsnetz Humantechnologie" }, "short": "QnHT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2014-09-30T02:00:00+02:00", "assignment": "2012-12-19T11:08:50+01:00", "program": null, "subprogram": null, "organization": 14026, "category": 10, "type": 10, "partner_function": 4, "manager": 51344, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3116-51344-10" ] }, { "id": 2834, "title": { "de": "Vitamin D3 Supplementierung bei polymorpher Lichtdermatose: Randomisierte doppelblinde plazebo-kontrollierte Studie", "en": "Vitamin D3 supplementation in polymorphic light eruption: Randomized double-blinded placebo-controlled trial" }, "short": "Vitamin D und polymorphe Lichtdermatose", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-10-01T02:00:00+02:00", "begin_effective": "2011-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-03-31T02:00:00+02:00", "assignment": "2012-04-04T13:19:59+02:00", "program": 108, "subprogram": "KLIF", "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 51618, "contact": 51618, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI132", "ethics_committee": null, "edudract_number": null, "persons": [ "2834-62056-12", "2834-51618-10" ] }, { "id": 2964, "title": { "de": "Die Rolle des IL-33/ST2 Signalwegs in Knorpelzellen aus der Wachstumsfuge", "en": "Investigating the role of the IL-33/ST2 signaling pathway in growth plate chondrocytes" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-10-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2014-09-30T02:00:00+02:00", "assignment": "2012-09-05T17:41:55+02:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 895 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2751, "title": { "de": "Pollen-Enzyme schädigen menschliche Tränenflüssigkeit und Zellen der Augenoberfläche - Ein Ansatz zum Verständnis des SNAK (saisonale nicht-allergische Konjunktivitis)-Syndroms.", "en": "Pollen enzymes degrade human tear fluid and cells of the ocular surface - an approach for understanding the SNAC (saisonal non-allergic conjunctivitis) syndrome." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-12-01T01:00:00+01:00", "begin_effective": "2012-02-01T01:00:00+01:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2018-12-31T01:00:00+01:00", "assignment": "2012-01-18T13:48:45+01:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2935, "title": { "de": "Validierung von MicroRNAs als neue Drug Targets beim hepatozellulären Karzinom", "en": "Validation of microRNAs as novel drug targets in hepatocellular carcinoma cancer cells" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-08-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2014-09-30T02:00:00+02:00", "assignment": "2012-07-26T11:33:50+02:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 50919, "contact": 50919, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 140 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2935-50919-10" ] }, { "id": 3447, "title": { "de": "Charakterisierung eines neuen familiäres kolorektales Syndrom X Prädispositionsgens", "en": "Characterization of a Novel Familial Colorectal Cancer Type X Predisposition Gene" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-09-01T02:00:00+02:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2014-09-01T02:00:00+02:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2013-11-27T09:50:43+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 77615, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1375 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3447-77615-10", "3447-51857-10" ] }, { "id": 2721, "title": { "de": "Kopfschmerz, Reaktive Sauerstoff und Stickstoff Studie", "en": "Headache, Reactive Oxygen and Nitrogen Study" }, "short": "HEADRON", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-09-01T02:00:00+02:00", "begin_effective": "2012-01-01T01:00:00+01:00", "end_planned": "2014-09-01T02:00:00+02:00", "end_effective": "2012-12-30T01:00:00+01:00", "assignment": "2012-01-12T09:20:38+01:00", "program": null, "subprogram": null, "organization": 14028, "category": 10, "type": 10, "partner_function": 4, "manager": 50562, "contact": 50562, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2721-50562-10" ] }, { "id": 3356, "title": { "de": "Elterlicher Stress bei Frühgeburt und pränatale Vorbereitung", "en": "Stress in parents of preterm infants and preparation of preterm birth" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-09-01T02:00:00+02:00", "begin_effective": "2013-09-01T02:00:00+02:00", "end_planned": "2014-08-31T02:00:00+02:00", "end_effective": "2014-08-31T02:00:00+02:00", "assignment": "2013-08-21T16:06:03+02:00", "program": null, "subprogram": null, "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": 50907, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3356-50907-10" ] } ] }