Project List
List projects.
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GET /v1/research/project/?format=api&offset=1680&ordering=-end_effective
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1700&ordering=-end_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1660&ordering=-end_effective", "results": [ { "id": 3261, "title": { "de": "Das MorquioBetter Projekt, Tel 2: Neue Chaperones für Defekte des GLB1-Gens", "en": "The MorquioBetter Project part II: Novel Chaperones for GLB1-defiicient diseses" }, "short": "MorquioBetter 2", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-05-01T02:00:00+02:00", "begin_effective": "2013-05-01T02:00:00+02:00", "end_planned": "2014-04-30T02:00:00+02:00", "end_effective": "2014-09-30T02:00:00+02:00", "assignment": "2013-05-03T12:42:18+02:00", "program": null, "subprogram": null, "organization": 14048, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1002 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3709, "title": { "de": "Veränderungen im Blutgefäßsystem der Plazenta als Folge von Schwangerschaftsdiabetes", "en": "Effect of Gestational Diabetes on placental vessels" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-04-15T02:00:00+02:00", "begin_effective": "2014-04-15T02:00:00+02:00", "end_planned": "2014-08-15T02:00:00+02:00", "end_effective": "2014-09-09T02:00:00+02:00", "assignment": "2014-07-17T10:54:41+02:00", "program": null, "subprogram": "Subventionsansuchen an die Stadt Graz/Wissenschaft", "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": 50674, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3709-50674-10" ] }, { "id": 2386, "title": { "de": "Europäisches Forschungs-Ethikkommissions-Netzwerk", "en": "European Research Ethics Committees Network" }, "short": "EURECNET", "url": "http://www.eurecnet.org/index.html", "abstract": { "de": null, "en": "EURECNET is a network that brings together national REC associations, networks or comparable initiatives but also other bodies relevant in the field of research involving human participants like National Ethics Councils and the European Commission's ethical review system. Such a network forms the infrastructural basis to promote awareness of specific working practices of RECs across Europe, to enhance the shared knowledge base of European RECs, to support coherent reviews and opinions and to meet new challenges and emerging ethical issues. The central objective of EURECNET as a Coordinating Action is to foster the already existing network of European REC networks (in short 'EUREC').\r\n\r\nIn particular, the contribution of EURECNET aims at five different levels:\r\n- fostering a sustainable infrastructure for European RECs (including a statute and a secretariat) to promote exchange and cooperation and to allow for international cooperation;\r\n- gathering information on RECs in Europe to build a basis for mutual exchange - collecting and evaluating training materials for REC members to enhance the quality of review;\r\n- conducting capacity building to facilitate the development of national REC networks (as future partners of EUREC);\r\n- identifying emerging ethical issues to develop common solutions for challenges posed by new technologies and scientific methodologies." }, "begin_planned": "2009-07-01T02:00:00+02:00", "begin_effective": "2011-03-01T01:00:00+01:00", "end_planned": "2012-06-30T02:00:00+02:00", "end_effective": "2014-08-31T02:00:00+02:00", "assignment": "2011-01-31T12:01:32+01:00", "program": 24, "subprogram": "Area: 5.1.1.2 Research on Ethics in science and technology\r\nTopic: SiS-2009-1.1.2.2 Networking and capacity-building activities to support ethics committees:", "organization": 14038, "category": 10, "type": 10, "partner_function": 2, "manager": 51627, "contact": 51627, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "244519", "ethics_committee": null, "edudract_number": null, "persons": [ "2386-51627-10" ] }, { "id": 3356, "title": { "de": "Elterlicher Stress bei Frühgeburt und pränatale Vorbereitung", "en": "Stress in parents of preterm infants and preparation of preterm birth" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-09-01T02:00:00+02:00", "begin_effective": "2013-09-01T02:00:00+02:00", "end_planned": "2014-08-31T02:00:00+02:00", "end_effective": "2014-08-31T02:00:00+02:00", "assignment": "2013-08-21T16:06:03+02:00", "program": null, "subprogram": null, "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": 50907, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3356-50907-10" ] }, { "id": 2463, "title": { "de": "European High Security BSL4 Laboratories", "en": "European High Security BSL4 Laboratories" }, "short": "ERINHA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-06-01T02:00:00+02:00", "begin_effective": "2010-11-01T01:00:00+01:00", "end_planned": "2013-05-31T02:00:00+02:00", "end_effective": "2014-08-31T02:00:00+02:00", "assignment": "2011-04-12T14:42:14+02:00", "program": 24, "subprogram": "Infrastructures\r\nINFRA-2010-2.2.8", "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": 51663, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2463-51663-10" ] }, { "id": 2757, "title": { "de": "Genomweite Kopienzahlvariationen bei bipolar affektiver Störung", "en": "Genome-wide CNV screening in bipolar affective disorder" }, "short": "CNVs bei bipolarer Störung", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-01-01T01:00:00+01:00", "begin_effective": "2012-02-01T01:00:00+01:00", "end_planned": "2013-03-13T01:00:00+01:00", "end_effective": "2014-08-31T02:00:00+02:00", "assignment": "2012-01-19T12:45:01+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 50654, "contact": 50654, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2757-50654-10" ] }, { "id": 3527, "title": { "de": "Genetik und Epigenetik der Uhrengene und Adipositas in der Bipolaren Störung", "en": "Genetics and Epigenetics of Clock Genes and Obesity in Bipolar Disorder" }, "short": "Clock Genes&Obesity in Bipolar Disorder", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-04-01T02:00:00+02:00", "begin_effective": "2013-08-01T02:00:00+02:00", "end_planned": "2014-08-01T02:00:00+02:00", "end_effective": "2014-08-01T02:00:00+02:00", "assignment": "2014-01-22T12:40:43+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 79771, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3527-79771-10" ] }, { "id": 3309, "title": { "de": "Biomarker ErKennenLernen, Projektnr: 839728", "en": "Biomarker ErKennenLernen" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-10-01T02:00:00+02:00", "begin_effective": "2013-08-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2014-07-31T02:00:00+02:00", "assignment": "2013-06-21T10:07:47+02:00", "program": null, "subprogram": null, "organization": 28394, "category": 10, "type": 10, "partner_function": 2, "manager": 58453, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "839728 ", "ethics_committee": null, "edudract_number": null, "persons": [ "3309-58453-10" ] }, { "id": 3355, "title": { "de": "Schwangerschaftserkrankungen - Die Rolle von Metalloproteinasen und Endothelin ", "en": "The role of placental metalloproteinases in inflammation-associated pregnancy diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2015-03-31T02:00:00+02:00", "end_effective": "2014-07-31T02:00:00+02:00", "assignment": "2013-08-20T15:17:51+02:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2655, "title": { "de": "Doktoratskolleg \"Metabolische und kardiovaskuläre Erkrankungen\" ", "en": "Doktoratskolleg: \"Metabolic and cardiovascular disease\"" }, "short": "DK_METABOL_DISORDERS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2009-03-01T01:00:00+01:00", "begin_effective": "2010-07-01T02:00:00+02:00", "end_planned": "2012-02-28T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2010-10-20T13:09:58+02:00", "program": 66, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 2, "manager": 51860, "contact": 51860, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1226", "ethics_committee": null, "edudract_number": null, "persons": [ "2655-51860-10" ] }, { "id": 2654, "title": { "de": "Doktoratskolleg \"Metabolische und kardiovaskuläre Erkrankungen\" ", "en": "Doktoratskolleg \"Metabolic disorders and cellular dysfunction\" " }, "short": "DK_METABOL_DISORDERS", "url": null, "abstract": { "de": "Proteomic investigation of lipotoxicity in tumor-associated cachexia\r\nObjective: To elucidate possible causes and effects of tumor-induced lipotoxicity on the proteome level.\r\nCachexia is commonly recognized as progressive weight loss with depletion of host reserves of adipose tissue and skeletal muscle and associated with cancers of gastrointestinal tract and lung. Survival of cancer patients is directly related to weight loss. The reduction of food intake alone is unable to explain the metabolic changes seen in cachexia. Moreover, loss of muscle and adipose tissue precedes the fall in food intake. The causes and mechanisms responsible for tumor-associated cachexia remain to be unravelled. Preliminary data generated in Gerald Hoefler´s laboratory demonstrate an involvement of adipose triglyceride lipase (ATGL) in the development of cachexia. While implantation of Lewis lung carcinoma cells into wild-type mice resulted in a vast reduction of gastrognemious muscle and white adipose tissue and a minor reduction in heart weight, none of these effects were seen in ATGL-ko mice.\r\nTissues from cachexia mouse models will be obtained from G. Hoefler. Proteomes from gastrognemious muscle, adipose tissues, liver, heart and spleen of wild-type and ATGL-ko mice with and without transplanted tumor will be profiled with respect to protein abundance by differential gelelectrophoresis (DIGE) and/or isotope labeling, liquid chromatography and mass spectrometry (LC-MS). Phosphoproteomics of selected cellular fractions will be performed using immobilized metal affinity chromatography (IMAC, TiO2) for phosphopeptide enrichment, isotopic labeling for quantification, LC-MS with phospho-group neutral loss scanning and database search for phospho-group modifications. Differences in lipase and esterase activities will be assessed by activity-based proteomics employing suitable probes (developed by the applicant) and by standard proteomic techniques.\r\n\r\nRegulatory and compensatory mechanisms of lipolytic pathways\r\nBackground: While the lipolytic proteome of mouse adipose tissue has been identified (3), many of the underlying regulatory processes remain unknown. Therefore, regulatory and compensatory mechanisms of lipolytic pathways as well as changes in the overall proteome will be determined upon shut down of individual pathways (e.g. in hormone sensitive lipase (HSL)- and ATGL-deficient mice). The phenotypes of the respective mouse models differ greatly with regard to body weight, lipid accumulation, fertility and organ specific defects. Thus, large effects are expected to be observed on the protein level in adipose and other tissues as well as in macrophages and foam cells.\r\nObjective: To elucidate the underlying regulatory, compensatory and pathogenic mechanisms of lipid accumulation on the proteome level.\r\nProteins interacting with recently identified lipases, as well as lipid droplet-associated proteins, which might regulate substrate accessibility, will be isolated from tissue fractions or cell lines, identified by LC-MS and analyzed for the presence of isomers and post-translational modifications, especially phosphorylation. Related tissue/cell fractions or immunoprecipitations will be profiled with respect to protein abundance by DIGE and/or isotopic labelling and LC-MS. Selected proteins will be confirmed by Western blotting. Phosphoproteomics and activity-based proteomics will be applied as described in Project 1.\r\n", "en": null }, "begin_planned": "2009-03-01T01:00:00+01:00", "begin_effective": "2010-07-01T02:00:00+02:00", "end_planned": "2012-02-28T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2010-10-20T13:09:58+02:00", "program": 66, "subprogram": null, "organization": 28394, "category": 10, "type": 10, "partner_function": 2, "manager": 58794, "contact": 58794, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1226", "ethics_committee": null, "edudract_number": null, "persons": [ "2654-58794-10" ] }, { "id": 2351, "title": { "de": "Effekte einer Vitamin D Supplementierung auf die arterielle Gefäßsteifigkeit in Vitamin D deffzienten Patienten mit Typ 2 Diabetes (EVITDAS-DM) - eine randomisierte doppelblinde Studie", "en": "Effects of Vitamin D supplementation on arterial stiffness in Vitamin D defficient patients with type 2 diabetes mellitus (EVITDAS-DM) - a randomized double-blind placebo controlled trial" }, "short": "EVITDAS-DM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-08-01T02:00:00+02:00", "begin_effective": "2011-01-01T01:00:00+01:00", "end_planned": "2013-08-31T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2010-12-06T11:49:18+01:00", "program": 79, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 4, "manager": 50877, "contact": 50877, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2351-50877-10" ] }, { "id": 3350, "title": { "de": "Etablierung eines in-vitro Modells zur Stimmlippenvernarbung", "en": "Establishment of an in-vitro model for vocal fold scarring" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-08-01T02:00:00+02:00", "begin_effective": "2013-08-01T02:00:00+02:00", "end_planned": "2014-07-31T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2013-08-14T11:38:53+02:00", "program": null, "subprogram": null, "organization": 14068, "category": 10, "type": 10, "partner_function": 4, "manager": 50670, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3350-50562-12", "3350-50464-12", "3350-50670-10" ] }, { "id": 2400, "title": { "de": "Etablierung einer Forschungsinfrastruktur für Biobanken und biologische Ressourcen an der Medizinischen Universität Graz", "en": "-" }, "short": "Biobank der MUG ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-01-01T01:00:00+01:00", "begin_effective": "2010-11-01T01:00:00+01:00", "end_planned": "2014-06-30T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2011-02-08T09:39:21+01:00", "program": 75, "subprogram": null, "organization": 28392, "category": 10, "type": 10, "partner_function": 4, "manager": 54033, "contact": 54033, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 55 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2400-54033-10" ] }, { "id": 3329, "title": { "de": " Molekulare Wirkungsweise von therapeutische Antikörper in der Lymphomtherapie ", "en": " Molecular Mechanism of therapeutic Antibodies in Lymphomatherapy " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-02-01T01:00:00+01:00", "begin_effective": "2013-07-01T02:00:00+02:00", "end_planned": "2013-10-31T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2013-07-15T12:59:46+02:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 59183, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3329-59183-10" ] }, { "id": 3015, "title": { "de": "Langzeitergebnisse nach operativer versus konservativer Klumpfußbehandlung", "en": "Longterm outcomes of operative versus conservative clubfoot treatment" }, "short": "LOKK", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-09-01T02:00:00+02:00", "begin_effective": "2012-11-01T01:00:00+01:00", "end_planned": "2013-07-01T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2012-10-25T10:05:43+02:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 54144, "contact": 54144, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3015-54144-10" ] }, { "id": 3047, "title": { "de": "Bild- und Tiefeninformation zur automatischen Lagekorrektur von Patienten in medizinischen Geräten", "en": "Bild- und Tiefeninformation zur automatischen Lagekorrektur von Patienten in medizinischen Geräten" }, "short": "BTAL", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-05-01T02:00:00+02:00", "begin_effective": "2012-05-01T02:00:00+02:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2012-11-21T14:39:21+01:00", "program": null, "subprogram": "HTI-Call 2012", "organization": 14043, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2660, "title": { "de": "Doktoratskolleg \"Metabolische und kardiovaskuläre Erkrankungen\" ", "en": "Doktoratskolleg: \"Metabolic and cardiovascular disease\"" }, "short": "DK_METABOL_DISORDERS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2009-03-01T01:00:00+01:00", "begin_effective": "2010-07-01T02:00:00+02:00", "end_planned": "2012-02-28T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2010-10-20T13:09:58+02:00", "program": 66, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1226", "ethics_committee": null, "edudract_number": null, "persons": [ "2660-66436-12" ] }, { "id": 2661, "title": { "de": "Doktoratskolleg \"Metabolische und Kardiovaskuläre Erkrankungen\"", "en": "Doktoratskolleg: \"Metabolic and cardiovascular disease\"" }, "short": "DK_METABOL_DISORDERS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2009-03-01T01:00:00+01:00", "begin_effective": "2010-07-01T02:00:00+02:00", "end_planned": "2012-02-28T01:00:00+01:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2010-10-20T13:09:58+02:00", "program": 66, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1226", "ethics_committee": null, "edudract_number": null, "persons": [ "2661-51663-10" ] }, { "id": 3554, "title": { "de": "Darmflora bei metabolischem Syndrom: Einfluss eines probiotischen Milchgetränks", "en": "Gut microbiota in metabolic syndrome: Influence of a probiotic milk drink " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-09-01T02:00:00+02:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2014-04-01T02:00:00+02:00", "end_effective": "2014-06-30T02:00:00+02:00", "assignment": "2014-02-05T14:27:45+01:00", "program": null, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 50989, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3554-50989-10" ] } ] }