Project List
List projects.
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GET /v1/research/project/?format=api&offset=1660&ordering=-end_planned
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1680&ordering=-end_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1640&ordering=-end_planned", "results": [ { "id": 2455, "title": { "de": "ACIB Austrian Center of industrial Biotechnology", "en": "ACIB Austrian Center of industrial Biotechnology" }, "short": "ACIB", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-04-01T02:00:00+02:00", "begin_effective": "2010-04-01T02:00:00+02:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2022-12-31T01:00:00+01:00", "assignment": "2011-03-28T14:35:51+02:00", "program": 94, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 58794, "contact": 58794, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2455-63257-12", "2455-58794-10" ] }, { "id": 3476, "title": { "de": "Hyperkapnie ist unter präklinischer Reanimation häufig und mit dem Outcome assoziiert", "en": "Hypercapnia is common during out-of-hospital cardiopulmonary resuscitation and affects outcome" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2013-12-19T11:38:05+01:00", "program": null, "subprogram": "Preis", "organization": 14081, "category": 10, "type": 10, "partner_function": 4, "manager": 54296, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1330 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3476-54296-10" ] }, { "id": 3016, "title": { "de": "Reduzierter Opioidverbrauch durch Physostigmin als Dauertropf zur postoperativen PCA - PHANOS (PHysostigmine-enHAnced Opioid analgeSia) Folgestudie", "en": "PHANOS - PHysostigmine-enHAnced Opioid analgeSia" }, "short": "PHANOS", "url": null, "abstract": { "de": "Zahlreiche Studien haben gezeigt, dass cholinerge Mechanismen eine zentrale Rolle im antinozizeptiven System spielen, indem sie synergistisch mit Morphin wirken und den postoperativen Opioidverbrauch reduzieren. Darüber hinaus hat das Anti-Cholinesterase-Medikament Physostigmin, das die synaptische Acetylcholin-Konzentration erhöht, entzündungshemmende Wirkungen. In dieser randomisierten, placebokontrollierten Studie mit 110 Patienten, die sich einer Nephrektomie unterzogen, untersuchten wir die Auswirkungen einer intraoperativen Physostigmin-Infusion von 0,5 mg h-1 i.v. über 24 Stunden auf den Opioidverbrauch, die Hyperalgesie, die Schmerzwerte und die Zufriedenheit mit der Schmerzkontrolle. \r\n\r\nÜbersetzt mit www.DeepL.com/Translator (kostenlose Version)", "en": "Several studies have shown that cholinergic mechanisms play a pivotal role in the anti-nociceptive system by acting synergistically with morphine and reducing postoperative opioid consumption. In addition, the anti-cholinesterase drug physostigmine that increases synaptic acetylcholine concentrations has anti-inflammatory effects. In this randomised placebo-controlled trial including 110 patients undergoing nephrectomy, we evaluated the effects of intraoperative physostigmine 0.5 mg h-1 i.v. for 24 h on opioid consumption, hyperalgesia, pain scores, and satisfaction with pain control. " }, "begin_planned": "2012-07-01T02:00:00+02:00", "begin_effective": "2012-11-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2013-07-30T02:00:00+02:00", "assignment": "2012-10-25T16:06:20+02:00", "program": null, "subprogram": "Land Steiermark unter 5.000,-", "organization": 14069, "category": 10, "type": 10, "partner_function": 4, "manager": 58422, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3016-58422-10", "3016-51915-12" ] }, { "id": 2951, "title": { "de": "Entwicklung von biofunktionellen, Kapselfibrose-vermeidenden Barriere-Schutzschichten für das Packaging von in-vivo Sensoren und Aktuatoren", "en": "Investigation of biofunctional, prevention-of-capsulefibrosis barrier protective layer for the packaging of in-vivo sensors and actuators" }, "short": "HTI:SMApp Sensor Packaging", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-07-01T02:00:00+02:00", "begin_effective": "2012-07-01T02:00:00+02:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-06-30T02:00:00+02:00", "assignment": "2012-08-28T10:52:02+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": "ABT08-35744/2014-3", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2870, "title": { "de": "Entwicklung von biofunktionellen, Kapselfibrose-vermeidenden Barriere-Schutzschichten für das Packaging von in-vivo Sensoren und Aktuatoren", "en": "Development of biofunctional non fibrosis inducing barrier protection layers for in-vivo sensors" }, "short": "HTI:SMApp Sensor Packaging", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-06-01T02:00:00+02:00", "begin_effective": "2012-07-01T02:00:00+02:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-06-30T02:00:00+02:00", "assignment": "2012-05-21T16:11:32+02:00", "program": null, "subprogram": "Forschung Steiermark Planung, Steuerung, Impulse\r\nHTI-Call Februar 2012", "organization": 17230, "category": 10, "type": 10, "partner_function": 2, "manager": 53900, "contact": 53900, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": "ABT08-35744/2014-3", "ethics_committee": null, "edudract_number": null, "persons": [ "2870-53900-10" ] }, { "id": 3225, "title": { "de": "Diagnostik und Klassifikation von pulmonaler Hypertonie mittels Herz-Magnetresonanzbildgebung ohne Einsatz von Kontrastmitteln", "en": "Non-contrast enhanced cardiac magnetic resonance imaging in the diagnosis and classification of pulmonary hypertension" }, "short": "CMR-PH2012", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-01-01T01:00:00+01:00", "begin_effective": "2013-03-25T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-12-31T01:00:00+01:00", "assignment": "2013-03-27T16:38:26+01:00", "program": null, "subprogram": null, "organization": 14104, "category": 10, "type": 10, "partner_function": 4, "manager": 53950, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3225-53950-10" ] }, { "id": 2432, "title": { "de": "BIOmarkers of Metabolic Homeostatic Robustness for Nutrition-derived Health CLAIMS Made on Food [BIOCLAIMS]", "en": "BIOmarkers of Metabolic Homeostatic Robustness for Nutrition-derived Health CLAIMS Made on Food [BIOCLAIMS]" }, "short": "BIOCLAIMS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-01-01T01:00:00+01:00", "begin_effective": "2010-03-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-02-28T01:00:00+01:00", "assignment": "2011-02-28T11:51:34+01:00", "program": 24, "subprogram": "KBBE-2009-2-2-03", "organization": 14084, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": " 244995", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3301, "title": { "de": "MULTI-CENTER INTER OBSERVER STUDIE ZUR MESSUNG VON SUBKUTANEN FETTSCHICHTEN MIT ULTRASCHALL", "en": "BODY COMPOSITION ASSESSMENT: ULTRASOUND FAT MEASUREMENT MULTI-CENTRE INTER-OBSERVER STUDY" }, "short": "MULTI-CENTRE INTER-OBSERVER STUDY", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-06-01T02:00:00+02:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-12-31T01:00:00+01:00", "assignment": "2013-06-17T10:46:27+02:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 3, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3625, "title": { "de": "Vitamin D bindendes Protein (DBP) und die Effizienz einer Vitamin D Einnahme in der Steirischen Vitamin D Bluthochdruckstudie", "en": "Vitamin D binding protein (DBP) and the efficiency of vitamin D supplementation in the Styrian Hypertension Study" }, "short": "DBP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-03-01T01:00:00+01:00", "begin_effective": "2014-03-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2014-04-03T12:34:07+02:00", "program": null, "subprogram": "ÖGKM Projektpreis", "organization": 14080, "category": 10, "type": 10, "partner_function": 1, "manager": 81051, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1565 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3625-81051-10" ] }, { "id": 3495, "title": { "de": "Does an altered expression of HCN channel isoforms underlie the observed changes in electrophysiological characteristics of the pacemaker current If in cardiomyocytes isolated from a pig model of atrial fibrillation and arterial hypertension?", "en": "Does an altered expression of HCN channel isoforms underlie the observed changes in electrophysiological characteristics of the pacemaker current If in cardiomyocytes isolated from a pig model of atrial fibrillation and arterial hypertension?" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2014-01-02T15:01:14+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 50969, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3495-50615-12", "3495-50969-10", "3495-50990-12" ] }, { "id": 3372, "title": { "de": "Über den Einfluß einer mechanischen Stimulierung auf die Regeneration von durch Platelet-rich Plasma stimulierte Zellen der menschlichen Rotatorenmanschette", "en": "Impact of Mechanical Stimulation on Fibroblast Proliferation of the Human Rotator Cuff using Platelet-rich Plasma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2013-09-17T15:45:41+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 4, "manager": 59379, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1270 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3372-50696-12", "3372-59782-12", "3372-61131-12", "3372-59379-10" ] }, { "id": 3577, "title": { "de": "Vergleich der von Qualitätssicherung und Qualitätskontrolle in der Diagnostischen Radiologie von Österreich und Montenegro", "en": "Comparision of QA/QC in diagnostic radiology in Montenegro and Austria" }, "short": " ME 10/2013", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2014-02-17T15:34:51+01:00", "program": 92, "subprogram": "WTZ -- Wissenschaftlich technische Zusammenarbeit -- wurde verlängert bis 30.6.2015", "organization": 14106, "category": 10, "type": 10, "partner_function": 1, "manager": 51913, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3577-51913-10" ] }, { "id": 2647, "title": { "de": "Die Rolle von GPR55 in der humanen Trophoblastdifferenzierung", "en": "The role of G-protein coupled receptor (GPR) 55 in human trophoblast differentiation" }, "short": "GPR_HUMAN TROPHOBLAT DIFFERENTIATION", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-01-01T01:00:00+01:00", "begin_effective": "2012-05-01T02:00:00+02:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-10-31T01:00:00+01:00", "assignment": "2011-11-24T11:22:38+01:00", "program": 72, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 53232, "contact": 53232, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P23859", "ethics_committee": null, "edudract_number": null, "persons": [ "2647-53232-10" ] }, { "id": 3954, "title": { "de": "Weiterführung LBI HI - LBG", "en": "Weiterführung LBI HI - LBG" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-05-01T02:00:00+02:00", "begin_effective": "2014-05-01T02:00:00+02:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2015-03-24T10:59:43+01:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 19 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3496, "title": { "de": "Protein kinase D2 (PRKD2): a candidate regulator of glioblastoma metabolism", "en": "Protein kinase D2 (PRKD2): a candidate regulator of glioblastoma metabolism" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2014-01-02T15:06:25+01:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 50990, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3496-50990-10" ] }, { "id": 3473, "title": { "de": "Eukaryotische Initiationsfaktoren in pädiatrischen Hirntumoren", "en": "Eukaryotische Initiationsfaktoren in pädiatrischen Hirntumoren" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-12-15T01:00:00+01:00", "begin_effective": "2013-12-15T01:00:00+01:00", "end_planned": "2014-12-15T01:00:00+01:00", "end_effective": "2019-06-30T02:00:00+02:00", "assignment": "2013-12-17T15:15:42+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2336, "title": { "de": "Multiskalen-Modellierung von Kalzium-vermittelter getriggerter Aktivität im Herzen", "en": "Multi-scale Modeling of Calcium Mediated Triggered Activity in the Heart" }, "short": "Calcium_Mediated_Heart_Activity", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2010-12-01T01:00:00+01:00", "begin_effective": "2011-01-01T01:00:00+01:00", "end_planned": "2014-12-01T01:00:00+01:00", "end_effective": "2015-06-30T02:00:00+02:00", "assignment": "2010-11-10T12:06:47+01:00", "program": null, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 2, "manager": 50966, "contact": 50966, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 724 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2336-50966-10" ] }, { "id": 3165, "title": { "de": "Phenotyping Fragile X Syndrome for the first two years of life", "en": "Phenotyping Fragile X Syndrome for the first two years of life" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-12-01T01:00:00+01:00", "begin_effective": "2012-12-01T01:00:00+01:00", "end_planned": "2014-11-30T01:00:00+01:00", "end_effective": "2014-11-30T01:00:00+01:00", "assignment": "2013-02-06T14:50:06+01:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 2785, "title": { "de": "Genetische Analyse der Multiplen Chemikalien-Sensitivität (MCS) mit Exom-Sequenzierung", "en": "Analysis of the genetic basis of multiple chemical sensitivity (MCS) by exome sequencing" }, "short": "MCSEXOM", "url": null, "abstract": { "de": "Multiple Chemikalien-Sensitivität (MCS) ist ein Krankheitsbild der Umweltmedizin, das unzureichend charakterisiert ist und nur symptomatisch im Ausschlussverfahren diagnostiziert werden kann, da die genaue Pathogenese unbekannt ist. Das vorliegende Projekt will herausfinden, ob (1) Exom-Sequenzierung genetische Risikofaktoren für MCS identifizieren kann, (2) MCS mit genetisch bedingten Unterschieden molekularer Chemosensoren zusammenhängt und (3) Genvarianten, MCS-Symptome und psychometrische Eigenschaften der Patienten/innen zusammenhängen. Erstmals an MCS-PatientInnen angewandt, kann die kostengünstige Technologie der Exom-Sequenzierung ganz neue genetische\r\nRisikofaktoren und Gen-Komplexe mit Relevanz für MCS aufklären. Außerdem wird mit dieser Methode untersucht, ob MCS-PatientInnen deshalb verstärkt auf Chemikalien reagieren, weil Unterschiede in den Genen für Chemosensoren eine\r\nChemikalienüberempfindlichkeit bedingen.", "en": "Multiple chemical sensitivity (MCS) is an environmental illness of unkown aetiology. Since evidence for an involvement of xenobiotic-metabolizing enzymes is lacking, the current proposal will test the hypotheses that (1) genetic risk factors for MCS can be identified by exome sequencing and (2) MCS is related to polymorphisms in genes relevant to chemosensation. First applied to MCS patients, exome sequencing will break new ground in the elucidation of the genetic basis of this illness. This cost-efficient technology will identify not only target genes associated with MCS but also complex genetic patterns underlying MCS. Exome sequencing will also be used to examine whether MCS is due to exaggerated chemosensation, because\r\npolymorphisms in genes relevant to chemosensation are likely to predispose for hypersensitivity to chemicals. In these goals, the project has great potential in identifying a possibly genetic cause of MCS and providing leads for the diagnosis and therapy\r\nof MCS." }, "begin_planned": "2011-12-01T01:00:00+01:00", "begin_effective": "2012-02-01T01:00:00+01:00", "end_planned": "2014-11-30T01:00:00+01:00", "end_effective": "2014-11-30T01:00:00+01:00", "assignment": "2012-02-14T14:26:33+01:00", "program": 90, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 3, "manager": 51529, "contact": 51529, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 957 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2785-51529-10" ] }, { "id": 3236, "title": { "de": "Behandlung der kindlichen akuten lymphoblastischen Leukämie mit einem modifiziertem resourcenreduzierten BFM Protokoll im Kosovo: Messung des outcome mittels minimaler Resterkrankung durch Durchflusszytometrie und Evaluierung der Toxizität und Kosten (PP-03-2012)", "en": "Treatment of paediatric acute lymphoblastic leukaemia with a modified resource-conserved BFM protocol in Kosovo: Monitoring outcome using minimal residual disease evaluation by flow cytometry and evaluation of toxicity and costs (PP-03-2012)" }, "short": "ALL in Kosovo ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-02-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2014-11-14T01:00:00+01:00", "end_effective": "2015-06-30T02:00:00+02:00", "assignment": "2013-04-19T12:20:27+02:00", "program": 90, "subprogram": "\"HigherKOS Program\" ( OEZA 8116-02/2011) der Austrian Development Agency (ADA) - Agentur der Österreichischen Entwicklungszusammenarbeit (OEZA). ", "organization": 14092, "category": 10, "type": 10, "partner_function": 3, "manager": 51657, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1415 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3236-51657-10" ] } ] }