Project List
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GET /v1/research/project/?format=api&offset=1520&ordering=-begin_effective
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1540&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1500&ordering=-begin_effective", "results": [ { "id": 2911, "title": { "de": "Psoriasis, dysfunktionales HDL und koronare Herzkrankheit ", "en": "Psoriasis, dysfunctional HDL und coronary artery disease" }, "short": "Psoriasis verände3rt gutes Cholesterin", "url": null, "abstract": { "de": "Psoriasis, dysfunktionales HDL und koronare Herzkrankheit \r\n\r\nPsorias, eine chronisch entzündliche Hautererkrankung, betrifft etwa 3% der Menschen weltweit. Psoriasis ist ein eigenständiger erheblicher Risikofaktor für arterielle Erkrankungen des Herz-Kreislauf-Systems, die Ursachen für den beobachteten Zusammenhang sind jedoch unklar. In diesem Projektantrag soll untersucht werden, ob Psoriasis mit einer funktionellen Beeinträchtigung des high-density lipoproteins (HDL) assoziiert ist. Unter physiologischen Bedingungen vermittelt anti-atherogenes HDL den reversen Cholesterintransport und wirkt vaskuloprotektiv. Mittels massenspektroskopischen und biochemischen Analysen sollen Veränderungen im Proteom und in der Lipidzusammensetzung des HDL von Psoriasis Patienten im Vergleich zu gesunden Kontrollen untersucht werden. In weiterer Folge soll untersucht werden, ob eine veränderte HDL-Zusammensetzung mit einer funktionellen Beeinträchtigung des HDL-Partikels einhergeht. \r\n", "en": "Psoriasis, a very common skin disease, is nowadays considered as a systemic inflammatory condition. Psoriasis patients harbor an increased risk of myocardial infarction and stroke, and numerous studies indicate that psoriasis and cardiovascular disease - particularly atherosclerosis - share common pathogenic features. \r\nPatients with autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis have decreased levels of high-density lipoprotein (HDL), suggesting that HDL may be important in preventing autoimmunity and the loss of self-tolerance. Proposed mechanisms for the atheroprotective functions of HDL include reverse cholesterol transport, reduction of oxidative stress and potent anti-inflammatory effects. On the other hand, HDL was shown to lose its-anti-atherogenic properties by post-translational modifications such as oxidation and carbamylation. There is emerging evidence suggesting that anti-atherogenic activities of HDL cannot be described by its plasma concentrations alone. For example, cholesterol efflux capacity, a functional measure of HDL, has an inverse association with the likelihood of coronary artery disease independent of HDL-cholesterol levels. Recent studies that elucidated the proteome of HDL from healthy individuals and patients with coronary artery disease or renal disease by mass spectrometry revealed that the protein cargo is a major determinant of the anti-atherogenic and anti-inflammatory properties of HDL. As qualitative alterations of HDL seem to be directly linked with increased cardiovascular complications, we hypothesize that HDL from psoriatic patients might display defective cholesterol efflux capability and anti-oxidative activities. \r\n" }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2015-09-30T02:00:00+02:00", "assignment": "2012-07-06T12:57:50+02:00", "program": 79, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 53252, "contact": 53252, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "2911-53252-10" ] }, { "id": 3335, "title": { "de": "Development of micro medical analyzer for ammonia monitoring in expiratory gas of critically ill", "en": "Development of micro medical analyzer for ammonia monitoring in expiratory gas of critically ill" }, "short": "AMMSE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2016-03-31T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2013-07-17T10:58:16+02:00", "program": 105, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": 58323, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "840940", "ethics_committee": null, "edudract_number": null, "persons": [ "3335-58323-10" ] }, { "id": 3225, "title": { "de": "Diagnostik und Klassifikation von pulmonaler Hypertonie mittels Herz-Magnetresonanzbildgebung ohne Einsatz von Kontrastmitteln", "en": "Non-contrast enhanced cardiac magnetic resonance imaging in the diagnosis and classification of pulmonary hypertension" }, "short": "CMR-PH2012", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-01-01T01:00:00+01:00", "begin_effective": "2013-03-25T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-12-31T01:00:00+01:00", "assignment": "2013-03-27T16:38:26+01:00", "program": null, "subprogram": null, "organization": 14104, "category": 10, "type": 10, "partner_function": 4, "manager": 53950, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3225-53950-10" ] }, { "id": 3109, "title": { "de": "GENETISCHE ABERRATIONEN IN SUBTYPEN DES ADENOKARZINOMS DER LUNGE", "en": "Genetic aberrations in subtypes of pulmonary adenocarcinomas" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-15T01:00:00+01:00", "begin_effective": "2013-03-15T01:00:00+01:00", "end_planned": "2013-12-01T01:00:00+01:00", "end_effective": "2015-10-31T01:00:00+01:00", "assignment": "2012-12-13T14:59:25+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5498, "title": { "de": "Anti-atherogene Wirkung neuer Paraoxonase Substrate ", "en": "Athero-protective effects of novel paraoxonase\r\nsubstrates" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-01T01:00:00+01:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2014-02-28T01:00:00+01:00", "end_effective": "2014-03-31T02:00:00+02:00", "assignment": "2018-09-26T15:18:52+02:00", "program": null, "subprogram": "MUG-Start-Förderung", "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 62749, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5498-62749-10" ] }, { "id": 3207, "title": { "de": "Klumpfußbehandlung für Kinder in Mali mit der Ponseti-Methode", "en": "Treating Paediatric Clubfeet in Mali with the Ponseti Mathod" }, "short": "Mali", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-01T01:00:00+01:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2014-03-01T01:00:00+01:00", "end_effective": "2016-03-31T02:00:00+02:00", "assignment": "2013-03-12T11:07:57+01:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 54144, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3207-54144-10" ] }, { "id": 2916, "title": { "de": "ApoA-I und ApoJ beeinflussen den Amyloid-beta Metabolismus an der Blut-Hirn-Schranke", "en": "Implications of apoA-I and apoJ as modulators of amyloid beta metabolism in brain capillary endothelial cells of the blood-brain barrier" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2015-09-30T02:00:00+02:00", "end_effective": "2018-02-28T01:00:00+01:00", "assignment": "2012-07-17T12:22:27+02:00", "program": 72, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P24783", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3133, "title": { "de": "Graz Studie an Gesundheit und Altern", "en": "Graz Study on Health and Aging" }, "short": "GSHA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-12-01T01:00:00+01:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2015-03-31T02:00:00+02:00", "assignment": "2013-01-14T14:45:13+01:00", "program": null, "subprogram": "Subventionsansuchen Stadt Graz", "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 51912, "contact": 51912, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3133-51912-10" ] }, { "id": 3180, "title": { "de": "Spiegelbestimmung ausgewählter antimikrobieller Substanzen im Liquor cerebrospinalis bei pädiatrischen, hämato-/onkologischen Patienten", "en": "Levels of selected antimicrobial agents in cerebrospinal fluid (CSF) of paediatric haemato-/oncologic patients" }, "short": "Antimicrobials in CSF", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2017-12-31T01:00:00+01:00", "end_effective": "2017-03-31T02:00:00+02:00", "assignment": "2013-02-20T09:59:20+01:00", "program": null, "subprogram": "Land Steiermark < 5.000,- Euro", "organization": 14092, "category": 10, "type": 10, "partner_function": 4, "manager": 56810, "contact": 56810, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3180-56810-10" ] }, { "id": 2974, "title": { "de": "DK \"Molecular Fundametals of Inflammation\"", "en": "DK \"Molecular Fundametals of Inflammation\"" }, "short": "DK-MOLIN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-03-01T01:00:00+01:00", "begin_effective": "2013-03-01T01:00:00+01:00", "end_planned": "2016-02-28T01:00:00+01:00", "end_effective": "2017-10-30T01:00:00+01:00", "assignment": "2012-09-06T13:05:36+02:00", "program": 66, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 2, "manager": 51632, "contact": 51632, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1241", "ethics_committee": null, "edudract_number": null, "persons": [ "2974-56938-12", "2974-83661-12", "2974-51632-10" ] }, { "id": 3355, "title": { "de": "Schwangerschaftserkrankungen - Die Rolle von Metalloproteinasen und Endothelin ", "en": "The role of placental metalloproteinases in inflammation-associated pregnancy diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-04-01T02:00:00+02:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2015-03-31T02:00:00+02:00", "end_effective": "2014-07-31T02:00:00+02:00", "assignment": "2013-08-20T15:17:51+02:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3440, "title": { "de": "Der Basophilen-Aktivierungstest als Diskriminator zwischen Bienen- und Wespengiftallergie", "en": "Accuracy of the basophil activation test in the differentiation between bee and wasp venom allergy" }, "short": "ISIREDS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-11-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2012-10-31T01:00:00+01:00", "end_effective": "2014-12-31T01:00:00+01:00", "assignment": "2013-11-21T11:59:18+01:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 87717, "contact": 87717, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1161 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3440-87717-10" ] }, { "id": 3112, "title": { "de": "Entwicklung eines Fragebogens zur sexuellen Gesundheit von KrebspatientInnen", "en": "Development of a questionnaire for assessing sexual health in cancer patients" }, "short": "Sx Health", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-02-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2015-01-31T01:00:00+01:00", "end_effective": "2015-03-31T02:00:00+02:00", "assignment": "2012-12-17T11:17:51+01:00", "program": null, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 442 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3189, "title": { "de": "BBMRI-LPC - Großangelegte prospektive Kohortenstudien ", "en": "BBMRI-LPC - Large-scale prospective cohort studies " }, "short": "BBMRI-LPC", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2016-12-31T01:00:00+01:00", "end_effective": "2017-10-30T01:00:00+01:00", "assignment": "2013-02-27T11:31:58+01:00", "program": 24, "subprogram": "INFRA-2012-1.1.9", "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "313010", "ethics_committee": null, "edudract_number": null, "persons": [ "3189-51663-10" ] }, { "id": 3152, "title": { "de": "Cardiac awareness, arterielle Gefäßsteifigkeit, psychophysiologische Parameter und Persönlichkeit", "en": "Cardiac awareness, arterial stiffness, psychophysiological parameters and personality" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-20T02:00:00+02:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2013-10-20T02:00:00+02:00", "end_effective": "2013-12-30T01:00:00+01:00", "assignment": "2013-01-23T16:04:22+01:00", "program": null, "subprogram": null, "organization": 29447, "category": 10, "type": 10, "partner_function": 4, "manager": 60388, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3152-60388-10" ] }, { "id": 3137, "title": { "de": "Überwachung von Patienten mit colorektalen Karzinomen durch serielle Plasma DNA Untersuchungen", "en": "Monitoring colorectal cancer by serial plasma DNA analyses" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2014-12-31T01:00:00+01:00", "end_effective": "2015-01-31T01:00:00+01:00", "assignment": "2013-01-16T10:11:09+01:00", "program": 79, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3145, "title": { "de": "Mobilitätsförderung WTZ Österreich-China", "en": "Mobility grants WTZ Austria-China" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2016-01-31T01:00:00+01:00", "assignment": "2013-01-21T15:56:24+01:00", "program": null, "subprogram": null, "organization": 14044, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": "CN 09/2013", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3236, "title": { "de": "Behandlung der kindlichen akuten lymphoblastischen Leukämie mit einem modifiziertem resourcenreduzierten BFM Protokoll im Kosovo: Messung des outcome mittels minimaler Resterkrankung durch Durchflusszytometrie und Evaluierung der Toxizität und Kosten (PP-03-2012)", "en": "Treatment of paediatric acute lymphoblastic leukaemia with a modified resource-conserved BFM protocol in Kosovo: Monitoring outcome using minimal residual disease evaluation by flow cytometry and evaluation of toxicity and costs (PP-03-2012)" }, "short": "ALL in Kosovo ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-02-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2014-11-14T01:00:00+01:00", "end_effective": "2015-06-30T02:00:00+02:00", "assignment": "2013-04-19T12:20:27+02:00", "program": 90, "subprogram": "\"HigherKOS Program\" ( OEZA 8116-02/2011) der Austrian Development Agency (ADA) - Agentur der Österreichischen Entwicklungszusammenarbeit (OEZA). ", "organization": 14092, "category": 10, "type": 10, "partner_function": 3, "manager": 51657, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1415 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3236-51657-10" ] }, { "id": 3166, "title": { "de": "Zusammenhang zwischen IQ und Biofeedbackstrategien unter Berücksichtigung des körperlichen Aktivitätsniveaus Gibt es psychosomatische Intelligenz?", "en": "Association between IQ and biofeedback strategies with consideration of bodily activity: is there evidence for psychosomatic intelligence?" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-03-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2015-03-01T01:00:00+01:00", "end_effective": "2013-12-30T01:00:00+01:00", "assignment": "2013-02-06T16:32:49+01:00", "program": null, "subprogram": null, "organization": 29447, "category": 10, "type": 10, "partner_function": 4, "manager": 50774, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3166-50774-10" ] }, { "id": 3265, "title": { "de": "HOMAGE", "en": "HOMAGE" }, "short": "HOMAGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-11-01T01:00:00+01:00", "begin_effective": "2013-02-01T01:00:00+01:00", "end_planned": "2017-10-30T01:00:00+01:00", "end_effective": "2019-01-31T01:00:00+01:00", "assignment": "2013-05-13T17:29:05+02:00", "program": 24, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "305507", "ethics_committee": null, "edudract_number": null, "persons": [] } ] }