Project List
List projects.
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GET /v1/research/project/?format=api&offset=1400&ordering=-end_effective
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1420&ordering=-end_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1380&ordering=-end_effective", "results": [ { "id": 2792, "title": { "de": "Immunmodulierende Strategien für die Behandlung des Merkelzell-Karzinoms (IMMOMEC).", "en": "Immune modulating strategies for treatment of Merkel cell carcinoma (IMMOMEC)." }, "short": "IMMOMEC", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-10-01T02:00:00+02:00", "begin_effective": "2012-01-01T01:00:00+01:00", "end_planned": "2015-09-30T02:00:00+02:00", "end_effective": "2016-12-31T01:00:00+01:00", "assignment": "2012-02-15T16:29:57+01:00", "program": 24, "subprogram": "Health 2011.2.4.1-1 ", "organization": 14047, "category": 10, "type": 10, "partner_function": 3, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "277775", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3563, "title": { "de": "Neu Biomarker zur Beobachtung von kardiovaskulären Risiken nach Nierentransplantation", "en": "New Biomarkers for Monitoring of Vascular Calcification after Renal Transplantation" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2016-12-31T01:00:00+01:00", "assignment": "2014-02-10T14:20:55+01:00", "program": 79, "subprogram": null, "organization": 14073, "category": 10, "type": 10, "partner_function": 4, "manager": 51982, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3563-51982-10" ] }, { "id": 4006, "title": { "de": "Untersuchung der Rolle von p53 in gefasteter Leber", "en": "Elucidating the role of p53 in fasted liver" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-01-01T01:00:00+01:00", "begin_effective": "2015-01-01T01:00:00+01:00", "end_planned": "2016-12-31T01:00:00+01:00", "end_effective": "2016-12-31T01:00:00+01:00", "assignment": "2015-05-11T15:45:30+02:00", "program": null, "subprogram": "START - Med Uni Graz", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 89979, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4006-89979-10" ] }, { "id": 4184, "title": { "de": "Kohlendioxid (CO2) in der Anpassungsphase unmittelbar nach\r\nder Geburt: Verlauf und Einfluss auf den Sauerstoffgehalt des Gehirns\r\n- eine prospektive Beobachtungsstudie", "en": "Carbondioxid (CO2) during immediate transition after birth: course and influence on cerebral oxygenation\r\n- a prospective observational study\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-10-01T02:00:00+02:00", "begin_effective": "2015-10-01T02:00:00+02:00", "end_planned": "2016-10-01T02:00:00+02:00", "end_effective": "2016-12-31T01:00:00+01:00", "assignment": "2015-12-09T13:03:30+01:00", "program": null, "subprogram": "Kulturamt Stadt Graz", "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": 50907, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4184-50907-10" ] }, { "id": 4867, "title": { "de": "In situ detektion von Androgenrezeptor Spleißvarianten in Prostatakrebszellen ", "en": "In situ detection of Androgen Receptor splice variants in prostate cancer cells" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-01-01T01:00:00+01:00", "begin_effective": "2016-01-01T01:00:00+01:00", "end_planned": "2016-12-31T01:00:00+01:00", "end_effective": "2016-12-31T01:00:00+01:00", "assignment": "2017-03-03T13:04:09+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 66435, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4867-66435-10" ] }, { "id": 2448, "title": { "de": "Onco Track - Methods for systematic next generation oncology biomarker development", "en": "Onco Track - Methods for systematic next generation oncology biomarker development" }, "short": "OncoTrack", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2011-01-01T01:00:00+01:00", "begin_effective": "2011-01-01T01:00:00+01:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2016-12-31T01:00:00+01:00", "assignment": "2011-03-22T10:18:00+01:00", "program": 24, "subprogram": "IMI_FP7-Health.2010.4.2.9-6:Integrated data analyses and servicing.", "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "115234", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3793, "title": { "de": "Identifizierung von putativen Krebs-Stammzellen in Adenocarcinoma der Lunge mittels Next Generation Sequencing.", "en": "Biomarkers of putative cancer stem cells in adenocarcinoma of the lung identified by\r\nnext generation sequencing\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-10-01T02:00:00+02:00", "begin_effective": "2014-10-01T02:00:00+02:00", "end_planned": "2015-09-30T02:00:00+02:00", "end_effective": "2016-11-30T01:00:00+01:00", "assignment": "2014-10-23T11:54:42+02:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 122 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3793-50539-12", "3793-50563-12", "3793-59188-12" ] }, { "id": 3421, "title": { "de": "Wert des Ultraschalls bei der Hämochromatose Arthropathie.", "en": "Value of ultrasound in hemochromatosis associated arthropathy" }, "short": "Ultrasound in hemochromatosis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-11-01T01:00:00+01:00", "begin_effective": "2013-11-01T01:00:00+01:00", "end_planned": "2016-09-30T02:00:00+02:00", "end_effective": "2016-11-30T01:00:00+01:00", "assignment": "2013-11-05T14:35:06+01:00", "program": 108, "subprogram": "KLIF", "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 66227, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI308", "ethics_committee": null, "edudract_number": null, "persons": [ "3421-77590-12", "3421-66227-10" ] }, { "id": 3646, "title": { "de": "Determinants of Diet and Physical Activity; Knowledge Hub to integrate and develop infrastructure for research across Europe", "en": "Determinants of Diet and Physical Activity; Knowledge Hub to integrate and develop infrastructure for research across Europe" }, "short": "DEDIPAC KH", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-12-01T01:00:00+01:00", "begin_effective": "2013-12-01T01:00:00+01:00", "end_planned": "2016-11-30T01:00:00+01:00", "end_effective": "2016-11-30T01:00:00+01:00", "assignment": "2014-04-30T13:12:06+02:00", "program": null, "subprogram": "Joint Programming - \"A Healthy Diet for a Healthy Life\"", "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 25, 1029 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3646-51663-10" ] }, { "id": 4242, "title": { "de": "Elektronenmikroskopische Lokalisation nikotinischer Acetylcholinrezeptoren an einem neuronalen Bewegungsdetektor", "en": "Electron Microscopic Localisation of a Nicotinic Acetylcholine Receptor of a neuronal movement detector" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-11-19T01:00:00+01:00", "begin_effective": "2015-11-19T01:00:00+01:00", "end_planned": "2016-11-19T01:00:00+01:00", "end_effective": "2016-11-19T01:00:00+01:00", "assignment": "2016-01-21T11:13:20+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 50960, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4242-50960-10" ] }, { "id": 3501, "title": { "de": "Zelluläre Immunrekonstitution gegenüber dem Humanen Herpesvirus Typ 6 (HHV-6) bei Kindern und Jugendlichen nach allogener Stammzelltransplantion", "en": "Cellular Immune Reconstitution against Human Herpesvirus Type 6 (HHV-6) in Children and Adolescent after allogeneic Stem Cell Transplantation" }, "short": "HHV-6 Immunität nach SCT", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-01-01T01:00:00+01:00", "begin_effective": "2014-03-01T01:00:00+01:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2014-01-15T10:39:08+01:00", "program": 81, "subprogram": null, "organization": 14092, "category": 10, "type": 10, "partner_function": 4, "manager": 56810, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3501-91769-12", "3501-56810-10" ] }, { "id": 4017, "title": { "de": "MUGIES - Forschen macht schlau", "en": "MUGies" }, "short": "MUGIES", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-06-01T02:00:00+02:00", "begin_effective": "2015-06-01T02:00:00+02:00", "end_planned": "2016-10-31T01:00:00+01:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2015-05-21T10:40:38+02:00", "program": null, "subprogram": "FFG Talente Praktika für Schülerinnen und Schüler", "organization": 28394, "category": 10, "type": 10, "partner_function": 2, "manager": 58453, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 3023 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4017-58453-10" ] }, { "id": 3222, "title": { "de": "GPR55 in der Entwicklung des Kolonkarzinoms", "en": "GPR55 in tumorigenesis and metastasis of colon cancer" }, "short": null, "url": null, "abstract": { "de": "GPR55 in der Entwicklung des Kolonkarzinoms\r\nG Protein gekoppelte Rezeptoren spielen eine wichtige Rolle im Tumorwachstum und in der Metastasierung von Krebszellen und stellen somit ein wichtiges pharmakologisches Target für die Krebstherapie dar. Auf Grund seiner fördernden Wirkung in der Proliferation und Invasion von Tumorzellen, aber auch in der Angiogenese, ist der G Protein gekoppelte Rezeptor 55 (GPR55) in jüngster Zeit als ein mögliches neues Target in Erscheinung getreten. Das bioaktive Phospholipid Lysophosphatidylinositol (LPI) ist seit längerem als der endogene Ligand des GPR55 Rezeptors bekannt. Erhöhte LPI Werte wurden im Ovarialkarzinom nachgewiesen und lassen auf einen Zusammenhang zwischen der LPI/GPR55 Achse und Krebswachstum schließen.\r\nGPR55 ist auch in Epithelzellen des Darmtrakts vorhanden, was auf eine mögliche Rolle in der Entwicklung des Kolonkarzinoms vermuten läßt. Im vorliegenden Projekt untersuchen wir die Funktion von GPR55 und LPI in der Tumorgenese und in der Metastasierung des Kolonkarzinoms zuerst an Hand der Kolonkarzinom Zelllinien HCT116 und SW480. Dabei werden Proliferations-, Apoptose-, Migration- und Invasionsassays verwendet ebenso wie molekularbiologische Methoden, um LPI-induzierte Signaltransduktionswege zu untersuchen. In einem Kolitis-assoziierten Kolonkarzinom Modell der Maus soll die Bedeutung von GPR55 in der Tumorentstehung in vivo untersucht werden, insbesondere ob GPR55 an der Proliferation von malignen Zellen und der Expression von onkogenen Transkriptionsfaktoren, wie NF-kappa B und STAT3, beteiligt ist. Die Rolle von GPR55 in der Verbreitung der Kolonkarzinomzellen in Sekundärorgane soll in einem in vivo Metastasierungsmodell untersucht werden. An Hand von histologischen Schnitten und Biopsien von humanem Kolonkarzinomgewebe wollen wir schließlich noch die Bedeutung von GPR55 und LPI in der Entstehung des Kolonkarzinoms beim Menschen untersuchen. Das Projekt sollte wesentliche Aussagen bezüglich einer möglichen pharmakologischen Therapie gegen Dickdarmkrebs basierend auf GPR55 geben. Weiters soll es eine Aussage liefern, ob LPI als möglicher Biomarker bei Dickdarmkrebs Verwendung finden könnte. \r\n", "en": null }, "begin_planned": "2013-06-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2016-05-31T02:00:00+02:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2013-03-26T10:24:55+01:00", "program": 72, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 56687, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25633", "ethics_committee": null, "edudract_number": null, "persons": [ "3222-56687-10" ] }, { "id": 4018, "title": { "de": "MUGies - Forschen macht schlau", "en": "MUGies - Forschen macht schlau" }, "short": "MUGies ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-05-01T02:00:00+02:00", "begin_effective": "2015-05-01T02:00:00+02:00", "end_planned": "2016-10-31T01:00:00+01:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2015-05-21T10:42:08+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 4, "manager": 53237, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4018-53237-10" ] }, { "id": 4034, "title": { "de": "MUGIES - Forschen macht schlau", "en": "MUGIES - Forschen macht schlau" }, "short": "MUGies", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-06-01T02:00:00+02:00", "begin_effective": "2015-06-01T02:00:00+02:00", "end_planned": "2016-10-31T01:00:00+01:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2015-06-01T15:18:33+02:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 54018, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4034-54018-10" ] }, { "id": 3044, "title": { "de": "Identifizierung von Brustkrebsstammzell-assoziierten ultrakonservierten nicht-kodierenden RNAs und deren klinische Relevanz bei Patienten mit Brustkrebs", "en": "Identification of breast cancer stem cell-associated non-coding ultraconserved genes and their clinical relevance for breast cancer patients" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-12-01T01:00:00+01:00", "begin_effective": "2012-12-01T01:00:00+01:00", "end_planned": "2015-11-30T01:00:00+01:00", "end_effective": "2016-10-31T01:00:00+01:00", "assignment": "2012-11-16T13:59:33+01:00", "program": 79, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3044-100192-12", "3044-50229-12", "3044-65726-12", "3044-77970-12", "3044-59188-12" ] }, { "id": 4135, "title": { "de": "Neue therapeutische Agentien in der Chordomtherapie", "en": "New therapeutic agents for chordoma" }, "short": "chordoma drug screen", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-10-06T02:00:00+02:00", "begin_effective": "2014-10-06T02:00:00+02:00", "end_planned": "2016-10-05T02:00:00+02:00", "end_effective": "2016-10-05T02:00:00+02:00", "assignment": "2015-11-02T09:49:01+01:00", "program": 69, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": 50448, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "J 3640", "ethics_committee": null, "edudract_number": null, "persons": [ "4135-50448-10" ] }, { "id": 3131, "title": { "de": "Schwangerschaftserkrankungen-Die Rolle von Metalloproteinasen und Endothelin", "en": "Pregnancy diseases - The role of metalloproteinases and endothelin" }, "short": "Schwangerschaftserkrankungen", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2014-09-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2013-01-07T16:00:05+01:00", "program": 79, "subprogram": null, "organization": 14038, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4358, "title": { "de": "Ganzheitlicher Omics Zugang zur Allergischen Rhinitis", "en": "Holistic Omics approach to Allergic Rhinitis" }, "short": "Holistic Omics approach", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-01T02:00:00+02:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2016-09-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2016-03-14T14:45:03+01:00", "program": 103, "subprogram": null, "organization": 14066, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1824 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3052, "title": { "de": "Adrenerge Regulation der CaV1.2 L-Typ Kalziumkanäle Dynamik in Neuronen", "en": "Adrenergic regulation of CaV1.2 L-type calcium channel dynamics in neurons" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2012-10-01T02:00:00+02:00", "begin_effective": "2012-11-01T01:00:00+01:00", "end_planned": "2015-09-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2012-11-26T15:44:00+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25085", "ethics_committee": null, "edudract_number": null, "persons": [] } ] }