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GET /v1/research/project/?format=api&offset=1080&ordering=begin_planned
{ "count": 2266, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1100&ordering=begin_planned", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1060&ordering=begin_planned", "results": [ { "id": 5271, "title": { "de": "Liquid Biopsies for early Detection of Cancer - Modul 1 Investigation of size distribution, origin and dynamics of plasma DNA", "en": "Liquid Biopsies for early Detection of Cancer - Modul 1 Investigation of size distribution, origin and dynamics of plasma DNA" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-01T02:00:00+02:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2024-09-30T02:00:00+02:00", "end_effective": "2024-09-30T02:00:00+02:00", "assignment": "2018-02-16T13:26:49+01:00", "program": 97, "subprogram": null, "organization": 14021, "category": 10, "type": 10, "partner_function": 4, "manager": 50899, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 23 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5271-50899-10" ] }, { "id": 5640, "title": { "de": "Liquid Biopsy mittels Apherese", "en": "Liquid biopsy by apheresis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-02T02:00:00+02:00", "begin_effective": "2017-10-02T02:00:00+02:00", "end_planned": "2018-09-30T02:00:00+02:00", "end_effective": "2018-09-30T02:00:00+02:00", "assignment": "2019-01-24T14:25:18+01:00", "program": null, "subprogram": "ESMO Fellowship (European Society for Medical Oncology)", "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 86226, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5640-86226-10" ] }, { "id": 6370, "title": { "de": "Untersuchung der Insulinabhängigen globalen und lokalen H2O2 und NO• Signaltransduktionswegen in Kardiomyozyten", "en": "Shining a Light on Global and Local H2O2 and NO• Signals in Cardiac Insulin Signaling" }, "short": "Insulin med. Radikalbldg. Herzmuskelzell", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-30T01:00:00+01:00", "begin_effective": "2021-02-01T01:00:00+01:00", "end_planned": "2020-10-30T01:00:00+01:00", "end_effective": "2022-07-31T02:00:00+02:00", "assignment": "2020-12-15T12:00:05+01:00", "program": 69, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "J4113-B31", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5029, "title": { "de": "Dynamische MRT bei zerebraler Kleingefäßerkrankung", "en": "Understanding the pathophysiology of cerebral small vessel disease using dynamic MRI techniques" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2018-04-30T02:00:00+02:00", "end_effective": "2018-04-30T02:00:00+02:00", "assignment": "2017-08-07T16:31:44+02:00", "program": 103, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 70680, "contact": null, "status": 2, "research": 2, "grant": 20, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5029-70680-10" ] }, { "id": 5134, "title": { "de": "Mechanismen der Chemotherapieresistenz, Immunevasion und Krankheitsprogression bei Krebserkrankungen der Gallenwege: Fokus auf die miR-200-Famile nicht-protein-kodierender microRNAs.", "en": "Mechanisms of chemotherapy resistance, immune evasion and disease progression in biliary tract cancer: Focus on the miR-200-family of nonprotein-coding microRNAs." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2019-12-31T01:00:00+01:00", "assignment": "2017-11-24T09:43:17+01:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 92241, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5134-50229-12", "5134-92241-10" ] }, { "id": 5193, "title": { "de": "Polymorphismen im NLRP3-Inflammasom bei Patienten/-innen mit Uveitis", "en": "Gene Polymorphisms of the NLRP3-Inflammasome in Uveitis" }, "short": "NLRP3-Inflammasom und Uveitis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2018-11-01T01:00:00+01:00", "end_effective": "2018-03-31T02:00:00+02:00", "assignment": "2018-01-10T10:21:36+01:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 1, "manager": 93387, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5193-93387-10" ] }, { "id": 5078, "title": { "de": "Basalzellkarzinom Studie", "en": "BCC – basal cell carcinoma study" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2018-05-01T02:00:00+02:00", "end_effective": "2019-07-31T02:00:00+02:00", "assignment": "2017-09-28T17:10:48+02:00", "program": null, "subprogram": null, "organization": 27477, "category": 10, "type": 10, "partner_function": 4, "manager": 50826, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5078-50826-10" ] }, { "id": 5299, "title": { "de": "Entwicklung eines Grazer Notfallventilations- und Metabolismusmonitors", "en": "Development of an Emergency Ventilatory and Metabolic Monitor" }, "short": "VICA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-12-01T01:00:00+01:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2018-06-01T02:00:00+02:00", "end_effective": "2018-06-01T02:00:00+02:00", "assignment": "2018-02-27T13:51:07+01:00", "program": null, "subprogram": null, "organization": 14069, "category": 10, "type": 10, "partner_function": 4, "manager": 74176, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5299-74176-10" ] }, { "id": 5120, "title": { "de": "Fasten-induzierte p53 Aktivierung als Unterstützung zur Chemotherapie bei Leberkrebs", "en": "STARVATION-INDUCED P53 ACTIVATION TO SUPPORT LIVER CANCER CHEMOTHERAPY" }, "short": "p53 activation in liver cancer", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-12-01T01:00:00+01:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2019-11-30T01:00:00+01:00", "end_effective": "2019-11-30T01:00:00+01:00", "assignment": "2017-11-06T14:30:31+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 89979, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-26", "ethics_committee": null, "edudract_number": null, "persons": [ "5120-89979-10" ] }, { "id": 5405, "title": { "de": "Health Literacy und Diversity für SchülerInnen der Sekundarstufe I", "en": "Health Literacy und Diversity" }, "short": "Heli-D", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2020-12-31T01:00:00+01:00", "assignment": "2018-06-27T15:32:18+02:00", "program": null, "subprogram": null, "organization": 14076, "category": 10, "type": 10, "partner_function": 2, "manager": 80111, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2160 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5405-80111-10" ] }, { "id": 5227, "title": { "de": "Schlaganfallfolgen im jungen Erwachsenenalter – Einfluss von sozioökonomischen Status und Bildung als Chance!", "en": "Stroke in the young - the influence of socioeconomic state" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-03-01T01:00:00+01:00", "end_planned": "2019-12-21T01:00:00+01:00", "end_effective": "2020-03-01T01:00:00+01:00", "assignment": "2018-01-31T14:22:52+01:00", "program": null, "subprogram": "Land Steiermark: Referat Wissenschaft und Forschung: 4. Ausschreibung in der Reihe Polaritäten in der Wissensgesellschaft.", "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 66708, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135, 2160 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5227-66708-10" ] }, { "id": 5431, "title": { "de": "Koordination des Doktoratsprogramms: Inflammatorische Erkrankungen in der Schwangerschaft", "en": "Coordination of the Doctoral Program: Inflammatory Disorders in Pregnancy " }, "short": "DP-iDP", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-10-01T02:00:00+02:00", "end_planned": "2021-12-31T01:00:00+01:00", "end_effective": "2022-09-30T02:00:00+02:00", "assignment": "2018-09-26T15:31:56+02:00", "program": 114, "subprogram": "doc.funds", "organization": 14038, "category": 10, "type": 10, "partner_function": 3, "manager": 50442, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "Doc 31-B26", "ethics_committee": null, "edudract_number": null, "persons": [ "5431-50442-10", "5431-56938-12", "5431-59816-12", "5431-83661-12", "5431-90214-12", "5431-95608-12", "5431-100813-12", "5431-100803-12", "5431-105059-12" ] }, { "id": 5218, "title": { "de": "15d-PGJ2: ein möglicher Therapieansatz gegen Osteosarkom?", "en": "15-deoxy-Δ12,14-PGJ2 (15d-PGJ2): a plausible therapeutic agent against osteosarcoma?" }, "short": "15d-PGJ2 und Osteosarkom", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-10-01T02:00:00+02:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2021-10-31T02:00:00+02:00", "assignment": "2018-01-22T13:01:57+01:00", "program": 79, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 4, "manager": 50610, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5218-50610-10", "5218-50990-12", "5218-51705-12", "5218-101018-12" ] }, { "id": 5370, "title": { "de": "LipoLUNG: Adipose Triglyzerid Lipase bei Lungenkrebs", "en": "LipoLUNG: Molecular and metabolic roles of Adipocyte Triglyceride Lipase in lung cancer" }, "short": "LipoLUNG", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-10-01T02:00:00+02:00", "end_planned": "2021-12-31T01:00:00+01:00", "end_effective": "2023-09-30T02:00:00+02:00", "assignment": "2018-05-23T11:31:07+02:00", "program": 72, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 51691, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P30968", "ethics_committee": null, "edudract_number": null, "persons": [ "5370-50903-12", "5370-57409-12", "5370-51691-10" ] }, { "id": 5335, "title": { "de": "Vorhersage der richtigen Therapie bei Brustkrebs", "en": "Prediction of the correct therapy for breast cancer" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2018-12-31T01:00:00+01:00", "end_effective": "2019-06-30T02:00:00+02:00", "assignment": "2018-04-11T11:12:37+02:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 54142, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-28", "ethics_committee": null, "edudract_number": null, "persons": [ "5335-54142-10" ] }, { "id": 5178, "title": { "de": "Treatment of pediatric acute lymphoblastic leukemia with a modified resource-conserved BFM protocol in Kosovo: Monitoring outcome using minimal residual disease evaluation by flow cytometry and evaluation of toxicity and costs from dependence to independence", "en": "Treatment of pediatric acute lymphoblastic leukemia with a modified resource-conserved BFM protocol in Kosovo: Monitoring outcome using minimal residual disease evaluation by flow cytometry and evaluation of toxicity and costs from dependence to independence" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2019-10-31T01:00:00+01:00", "end_effective": "2019-12-31T01:00:00+01:00", "assignment": "2017-12-22T14:06:10+01:00", "program": null, "subprogram": null, "organization": 14092, "category": 10, "type": 10, "partner_function": 4, "manager": 51859, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1415 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5178-51859-10" ] }, { "id": 5260, "title": { "de": "Entwicklung genetisch kodierter K+-Fluoreszenzsensoren", "en": "Development of genetically encoded fluorescent K+ probes" }, "short": "Shining Light on (sub)cellular K+ fluxes", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-10-01T02:00:00+02:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2022-12-31T01:00:00+01:00", "assignment": "2018-02-15T10:36:01+01:00", "program": 64, "subprogram": "I - Internationale Projekte - Joint Project - Austria/Germany", "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 50810, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "3716-B27", "ethics_committee": null, "edudract_number": null, "persons": [ "5260-50810-10" ] }, { "id": 5197, "title": { "de": "HHcy und Atherosklerose: Molekulare Mechanismen und Pathophysiologie", "en": "Hyperhomocysteinemia and atherosclerosis: molecular mechanisms and pathophysiology" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-04-01T02:00:00+02:00", "end_planned": "2022-12-31T01:00:00+01:00", "end_effective": "2022-05-31T02:00:00+02:00", "assignment": "2018-01-10T14:05:54+01:00", "program": 72, "subprogram": null, "organization": 14028, "category": 10, "type": 10, "partner_function": 2, "manager": 52854, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P31105 ", "ethics_committee": null, "edudract_number": null, "persons": [ "5197-52854-10", "5197-56571-12" ] }, { "id": 5111, "title": { "de": "Erforschung des Reinke Ödems mittels Proteom-Analyse", "en": "Exploring Reinke’s Edema by Proteomic Analysis" }, "short": "Reinke Ödem", "url": null, "abstract": { "de": "Das Reinke Ödem (RÖ) ist eine ein- oder beidseitige Schwellung der Stimmlippen, die vor allem bei Nikotinabusus und Stimm-Missbrauch auftritt. Das Reinke Ödem ist durch eine erniedrigten Stimmlage und schlechte Stimmqualität gekennzeichnet, was den beruflichen Alltag vor allem von Personen in Sprechberufen (Lehrer, Call Center Agenten etc.) deutlich erschwert. Bis dato gibt es keine kausale Therapie für das RÖ, auch der Goldstandard der Therapie, Stimmlippenchirurgie, bringt keine zufriedenstellenden Ergebnisse und stellt keine kausale Therapie dar.\r\nIm vorgestellten Projekt wollen wir die zellulären Ursachen des RÖ mittels Protein Analyse (Proteomics) erforschen. Damit werden erstmals die kausalen Ursachen dieser Krankheit erforscht. Aus Schleimhaut Biopsien die während Stimmlippen-OPs betroffener Patienten entnommen werden, sollen spezifische RÖ-Stimmlippenzellen kultiviert und für weitere Analysen und Versuche vorbereitet werden. Die Proteomics Analyse liefert eine Auflistung aller Proteine, die diese Zellen produzieren. Diese sollen mit den Proteinen aus Stimmlippenzellen aus gesundem Gewebe verglichen werden.\r\nIn darauffolgenden funktionellen Experimenten sollen bestimmte Proteine („Kandidaten-Proteine“), die vor allem von RÖ-Fibroblasten produziert werden, auf ihre biologische Relevanz überprüft werden. Mittels Verstärkung oder Blockierung dieser Kandidaten Proteine können wesentliche Rückschlüsse auf die Krankheitsmechanismen von RÖ gezogen werden, die den Weg zu neuen (nicht-chirurgischen) Therapieformen ebnen sollen.\r\n", "en": "Reinke’s edema (RE) is a uni- or bilateral swelling of the vocal folds, occurring in patients with nicotine and voice abuse. Voice of patients is characterized by decreased pitch and detrimental voice quality, making it often difficult for voice professionals who rely on their voices (teacher, call center agents etc.)\r\nSo far treatment is only symptomatic, still the gold standard of therapy, microsurgery of the vocal folds, is far from being satisfactory. \r\nIn the proposed project we seek to explore the cellular mechanisms of RE by protein analysis (proteomics), revealing the true pathophysiology of RE for the first time. During routine vocal fold surgery for RE we will take small mucosa specimens. From these we will extract vocal fold fibroblasts for subsequent analysis. Proteomic analysis will deliver a complete list of proteins produces specifically by these cells. These will be compared with vocal fold cells grown out of healthy laryngeal mucosa. In subsequent functional experiments we will explore certain proteins of interest (aka. candidate proteins) that are produced in a high number by RE fibroblasts for their biological relevance. By enhancing or blocking these candidate proteins we aim to draw conclusions on their role in the development of RE, which should pave to way to new (non-surgical) treatment options.\r\n" }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2017-10-30T10:42:53+01:00", "program": 72, "subprogram": null, "organization": 14068, "category": 10, "type": 10, "partner_function": 4, "manager": 50670, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P30496", "ethics_committee": null, "edudract_number": null, "persons": [ "5111-50670-10", "5111-50698-12", "5111-51047-12", "5111-69755-12", "5111-77116-12", "5111-82902-12", "5111-51982-12", "5111-88652-12", "5111-103118-12", "5111-104099-12", "5111-58794-12", "5111-57544-12" ] }, { "id": 5145, "title": { "de": "Novel Bone Regeneration Drug Osteogrow:Therapeutic Solution for Lumbar Back Pain — OSTEOproSPINE", "en": "Novel Bone Regeneration Drug Osteogrow:Therapeutic Solution for Lumbar Back Pain — OSTEOproSPINE" }, "short": "OSTEOproSPINE_Horizon", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2023-12-31T01:00:00+01:00", "end_effective": "2023-06-30T02:00:00+02:00", "assignment": "2017-12-01T13:52:28+01:00", "program": 109, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "779340", "ethics_committee": null, "edudract_number": null, "persons": [ "5145-91941-12", "5145-59379-11" ] } ] }