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GET /v1/research/project/?format=api&offset=1060&ordering=-begin_effective
{ "count": 2329, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1080&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1040&ordering=-begin_effective", "results": [ { "id": 5470, "title": { "de": "Regulation des RGG-vermittelten Kernimports", "en": "Regulation of RGG-mediated Nuclear Import" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2021-12-31T01:00:00+01:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2018-09-06T16:11:59+02:00", "program": 111, "subprogram": "DACH", "organization": 14013, "category": 10, "type": 10, "partner_function": 3, "manager": 91207, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I3792", "ethics_committee": null, "edudract_number": null, "persons": [ "5470-91207-10", "5470-70700-12", "5470-98222-12", "5470-100416-12", "5470-101038-12" ] }, { "id": 5209, "title": { "de": "Echolab", "en": "Echolab" }, "short": "Echolab", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-02-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2018-08-31T02:00:00+02:00", "end_effective": "2019-06-30T02:00:00+02:00", "assignment": "2018-01-18T10:47:08+01:00", "program": null, "subprogram": null, "organization": 27477, "category": 10, "type": 10, "partner_function": 1, "manager": 50826, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5209-60041-11", "5209-50826-10" ] }, { "id": 5433, "title": { "de": "Health Literacy und Diversity für SchülerInnen der Sekundarstufe I ", "en": "Health literacy and diversity for children in secondary school level I " }, "short": "Heli-D", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2020-12-31T01:00:00+01:00", "assignment": "2018-08-08T11:10:59+02:00", "program": null, "subprogram": null, "organization": 27964, "category": 10, "type": 10, "partner_function": 2, "manager": 63287, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2160 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5433-63287-10" ] }, { "id": 5273, "title": { "de": "Erstellung eines Registers zur Erfassung von Patienten mit einer terminalen Herzinsuffizienz in der Steiermark", "en": "Establishment of a styrian end- stage heart failure registry " }, "short": "Styrian end-stage heart failure registry", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2018-12-31T01:00:00+01:00", "end_effective": "2018-12-31T01:00:00+01:00", "assignment": "2018-02-20T10:55:08+01:00", "program": null, "subprogram": "Kulturamt Stadt Graz", "organization": 14075, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 20, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5111, "title": { "de": "Erforschung des Reinke Ödems mittels Proteom-Analyse", "en": "Exploring Reinke’s Edema by Proteomic Analysis" }, "short": "Reinke Ödem", "url": null, "abstract": { "de": "Das Reinke Ödem (RÖ) ist eine ein- oder beidseitige Schwellung der Stimmlippen, die vor allem bei Nikotinabusus und Stimm-Missbrauch auftritt. Das Reinke Ödem ist durch eine erniedrigten Stimmlage und schlechte Stimmqualität gekennzeichnet, was den beruflichen Alltag vor allem von Personen in Sprechberufen (Lehrer, Call Center Agenten etc.) deutlich erschwert. Bis dato gibt es keine kausale Therapie für das RÖ, auch der Goldstandard der Therapie, Stimmlippenchirurgie, bringt keine zufriedenstellenden Ergebnisse und stellt keine kausale Therapie dar.\r\nIm vorgestellten Projekt wollen wir die zellulären Ursachen des RÖ mittels Protein Analyse (Proteomics) erforschen. Damit werden erstmals die kausalen Ursachen dieser Krankheit erforscht. Aus Schleimhaut Biopsien die während Stimmlippen-OPs betroffener Patienten entnommen werden, sollen spezifische RÖ-Stimmlippenzellen kultiviert und für weitere Analysen und Versuche vorbereitet werden. Die Proteomics Analyse liefert eine Auflistung aller Proteine, die diese Zellen produzieren. Diese sollen mit den Proteinen aus Stimmlippenzellen aus gesundem Gewebe verglichen werden.\r\nIn darauffolgenden funktionellen Experimenten sollen bestimmte Proteine („Kandidaten-Proteine“), die vor allem von RÖ-Fibroblasten produziert werden, auf ihre biologische Relevanz überprüft werden. Mittels Verstärkung oder Blockierung dieser Kandidaten Proteine können wesentliche Rückschlüsse auf die Krankheitsmechanismen von RÖ gezogen werden, die den Weg zu neuen (nicht-chirurgischen) Therapieformen ebnen sollen.\r\n", "en": "Reinke’s edema (RE) is a uni- or bilateral swelling of the vocal folds, occurring in patients with nicotine and voice abuse. Voice of patients is characterized by decreased pitch and detrimental voice quality, making it often difficult for voice professionals who rely on their voices (teacher, call center agents etc.)\r\nSo far treatment is only symptomatic, still the gold standard of therapy, microsurgery of the vocal folds, is far from being satisfactory. \r\nIn the proposed project we seek to explore the cellular mechanisms of RE by protein analysis (proteomics), revealing the true pathophysiology of RE for the first time. During routine vocal fold surgery for RE we will take small mucosa specimens. From these we will extract vocal fold fibroblasts for subsequent analysis. Proteomic analysis will deliver a complete list of proteins produces specifically by these cells. These will be compared with vocal fold cells grown out of healthy laryngeal mucosa. In subsequent functional experiments we will explore certain proteins of interest (aka. candidate proteins) that are produced in a high number by RE fibroblasts for their biological relevance. By enhancing or blocking these candidate proteins we aim to draw conclusions on their role in the development of RE, which should pave to way to new (non-surgical) treatment options.\r\n" }, "begin_planned": "2018-01-01T01:00:00+01:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2022-02-28T01:00:00+01:00", "assignment": "2017-10-30T10:42:53+01:00", "program": 72, "subprogram": null, "organization": 14068, "category": 10, "type": 10, "partner_function": 4, "manager": 50670, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P30496", "ethics_committee": null, "edudract_number": null, "persons": [ "5111-50670-10", "5111-50698-12", "5111-51047-12", "5111-69755-12", "5111-77116-12", "5111-82902-12", "5111-51982-12", "5111-88652-12", "5111-103118-12", "5111-104099-12", "5111-58794-12", "5111-57544-12" ] }, { "id": 5343, "title": { "de": "CD Labor für Gas- und Partikeltransport durch Papier", "en": "CD Laboratory for Gas and Particle Transport through Paper" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-01T02:00:00+02:00", "begin_effective": "2018-01-01T01:00:00+01:00", "end_planned": "2024-10-31T01:00:00+01:00", "end_effective": "2024-12-31T01:00:00+01:00", "assignment": "2018-04-16T11:35:10+02:00", "program": 97, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 2, "manager": 54018, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 23 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5343-54018-10" ] }, { "id": 5299, "title": { "de": "Entwicklung eines Grazer Notfallventilations- und Metabolismusmonitors", "en": "Development of an Emergency Ventilatory and Metabolic Monitor" }, "short": "VICA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-12-01T01:00:00+01:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2018-06-01T02:00:00+02:00", "end_effective": "2018-06-01T02:00:00+02:00", "assignment": "2018-02-27T13:51:07+01:00", "program": null, "subprogram": null, "organization": 14069, "category": 10, "type": 10, "partner_function": 4, "manager": 74176, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5299-74176-10" ] }, { "id": 5139, "title": { "de": "Immissions- und Emissionsmessungen von Bioaerosolen im Bereich von Geflügel- und Schweinestallungen", "en": "Emissions and Immissions of Bioaerosols in the Area of different Barns" }, "short": "LUQUASTA", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-09-01T02:00:00+02:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2020-10-01T02:00:00+02:00", "end_effective": "2021-06-30T02:00:00+02:00", "assignment": "2017-11-28T10:56:06+01:00", "program": 90, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 3, "manager": 50497, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 957 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5139-50497-10", "5139-51198-12" ] }, { "id": 5149, "title": { "de": "PREvention of STroke in Intracerebral haemorrhaGE survivors with Atrial Fibrillation (PRESTIGE-AF)", "en": "PREvention of STroke in Intracerebral haemorrhaGE survivors with Atrial Fibrillation (PRESTIGE-AF)" }, "short": "PRESTIGE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-07-01T02:00:00+02:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2022-06-30T02:00:00+02:00", "end_effective": "2024-11-30T01:00:00+01:00", "assignment": "2017-12-05T13:36:53+01:00", "program": 109, "subprogram": "Call: H2020-SC1-2016-2017 (Personalised Medicine)\r\nTopic: SC1-PM-10-2017\r\nType of action: RIA (Research and Innovation action)", "organization": 14051, "category": 10, "type": 10, "partner_function": 2, "manager": 50173, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "754517", "ethics_committee": null, "edudract_number": null, "persons": [ "5149-50173-10" ] }, { "id": 5126, "title": { "de": "Der Einfluss des Neuroblastoms und dessen Chemotherapie auf die volatilen organischen Substanzen im Stuhl", "en": "Influence of Neuroblastoma and its Chemotherapy on volatile organic compounds." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-09-01T02:00:00+02:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2018-12-31T01:00:00+01:00", "end_effective": "2018-11-30T01:00:00+01:00", "assignment": "2017-11-16T09:30:48+01:00", "program": null, "subprogram": null, "organization": 14049, "category": 10, "type": 10, "partner_function": 4, "manager": 50778, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5126-50778-10", "5126-54087-12", "5126-82670-12" ] }, { "id": 5120, "title": { "de": "Fasten-induzierte p53 Aktivierung als Unterstützung zur Chemotherapie bei Leberkrebs", "en": "STARVATION-INDUCED P53 ACTIVATION TO SUPPORT LIVER CANCER CHEMOTHERAPY" }, "short": "p53 activation in liver cancer", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-12-01T01:00:00+01:00", "begin_effective": "2017-12-01T01:00:00+01:00", "end_planned": "2019-11-30T01:00:00+01:00", "end_effective": "2019-11-30T01:00:00+01:00", "assignment": "2017-11-06T14:30:31+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 89979, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-26", "ethics_committee": null, "edudract_number": null, "persons": [ "5120-89979-10" ] }, { "id": 5029, "title": { "de": "Dynamische MRT bei zerebraler Kleingefäßerkrankung", "en": "Understanding the pathophysiology of cerebral small vessel disease using dynamic MRI techniques" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2018-04-30T02:00:00+02:00", "end_effective": "2018-04-30T02:00:00+02:00", "assignment": "2017-08-07T16:31:44+02:00", "program": 103, "subprogram": null, "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 70680, "contact": null, "status": 2, "research": 2, "grant": 20, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5029-70680-10" ] }, { "id": 5193, "title": { "de": "Polymorphismen im NLRP3-Inflammasom bei Patienten/-innen mit Uveitis", "en": "Gene Polymorphisms of the NLRP3-Inflammasome in Uveitis" }, "short": "NLRP3-Inflammasom und Uveitis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2018-11-01T01:00:00+01:00", "end_effective": "2018-03-31T02:00:00+02:00", "assignment": "2018-01-10T10:21:36+01:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 1, "manager": 93387, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5193-93387-10" ] }, { "id": 5078, "title": { "de": "Basalzellkarzinom Studie", "en": "BCC – basal cell carcinoma study" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2018-05-01T02:00:00+02:00", "end_effective": "2019-07-31T02:00:00+02:00", "assignment": "2017-09-28T17:10:48+02:00", "program": null, "subprogram": null, "organization": 27477, "category": 10, "type": 10, "partner_function": 4, "manager": 50826, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5078-50826-10" ] }, { "id": 5134, "title": { "de": "Mechanismen der Chemotherapieresistenz, Immunevasion und Krankheitsprogression bei Krebserkrankungen der Gallenwege: Fokus auf die miR-200-Famile nicht-protein-kodierender microRNAs.", "en": "Mechanisms of chemotherapy resistance, immune evasion and disease progression in biliary tract cancer: Focus on the miR-200-family of nonprotein-coding microRNAs." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-11-01T01:00:00+01:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2019-12-31T01:00:00+01:00", "assignment": "2017-11-24T09:43:17+01:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 92241, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5134-50229-12", "5134-92241-10" ] }, { "id": 5387, "title": { "de": "Motivation von Trainingsaktivitäten für Menschen mit Demenz mit Sozial Robotik und Dialog-gestütztem Coaching", "en": "Motivation of training activities for people with dementia with social robotics and dialogue-supported coaching" }, "short": "AMIGO", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-09-01T02:00:00+02:00", "begin_effective": "2017-11-01T01:00:00+01:00", "end_planned": "2019-08-31T02:00:00+02:00", "end_effective": "2020-06-30T02:00:00+02:00", "assignment": "2018-06-11T12:37:11+02:00", "program": null, "subprogram": "FFG benefit", "organization": 14509, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 3, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "865646", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4552, "title": { "de": "Die Rolle der Calmodulin Kinase II in der Herzinsuffizienz ", "en": "Calmodulin kinase II cascade in cardiac (patho)physiology" }, "short": "CaMKII und Herzinsuffizienz", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-10-01T02:00:00+02:00", "begin_effective": "2017-10-21T02:00:00+02:00", "end_planned": "2019-09-30T02:00:00+02:00", "end_effective": "2022-07-20T02:00:00+02:00", "assignment": "2016-08-09T14:57:20+02:00", "program": 87, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 62747, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "V 530-B27", "ethics_committee": null, "edudract_number": null, "persons": [ "4552-62747-10", "4552-75758-12" ] }, { "id": 5640, "title": { "de": "Liquid Biopsy mittels Apherese", "en": "Liquid biopsy by apheresis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-02T02:00:00+02:00", "begin_effective": "2017-10-02T02:00:00+02:00", "end_planned": "2018-09-30T02:00:00+02:00", "end_effective": "2018-09-30T02:00:00+02:00", "assignment": "2019-01-24T14:25:18+01:00", "program": null, "subprogram": "ESMO Fellowship (European Society for Medical Oncology)", "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 86226, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5640-86226-10" ] }, { "id": 5064, "title": { "de": "In vitro Studie zur Minimierung von Infektionen großer Endoprothesen ", "en": "In vitro study to minimize infections of large endoprostheses" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-10-01T02:00:00+02:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2020-06-30T02:00:00+02:00", "assignment": "2017-09-19T15:24:02+02:00", "program": 60, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 4, "manager": 50696, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "861608", "ethics_committee": null, "edudract_number": null, "persons": [ "5064-50696-10", "5064-59782-12", "5064-61131-12", "5064-87214-12" ] }, { "id": 4967, "title": { "de": "Der Einfluss von Angiotensin II auf das plazentale Fraktalkin", "en": "The role of angiotensin II on placental fractalkine" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2021-09-30T02:00:00+02:00", "assignment": "2017-05-24T14:53:01+02:00", "program": 71, "subprogram": "DACH", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 53232, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I 3304", "ethics_committee": null, "edudract_number": null, "persons": [ "4967-53232-10" ] } ] }