Project List
List projects.
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GET /v1/research/project/?format=api&offset=1040&ordering=begin_effective
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1060&ordering=begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1020&ordering=begin_effective", "results": [ { "id": 4416, "title": { "de": "Serratierte Lesionen bei chronisch-entzündlichen Darmerkrankungen: Genotyp-Phänotyp Korrelation.", "en": "Serrated lesions in inflammatory bowel disease: genotype-phenotype correlation." }, "short": "IBD und SSL", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-02-01T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2017-02-01T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2016-05-03T16:40:29+02:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 4, "manager": 92422, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1765 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4416-92422-10" ] }, { "id": 4194, "title": { "de": "PCK2 in Lungentumoren: Rolle für Metabolismus und Wachstum", "en": "The role of PCK2 in lung cancer metabolism and growth" }, "short": "PCK2 in Lungentumoren", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-11-01T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2018-10-31T01:00:00+01:00", "end_effective": "2020-09-30T02:00:00+02:00", "assignment": "2015-12-15T11:22:27+01:00", "program": 72, "subprogram": null, "organization": 14087, "category": 10, "type": 10, "partner_function": 4, "manager": 57557, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P28692", "ethics_committee": null, "edudract_number": null, "persons": [ "4194-58591-12", "4194-71794-12", "4194-81608-12", "4194-105621-12", "4194-57557-10" ] }, { "id": 4808, "title": { "de": "PR0STATAKREBS: neue Hoffnung dank alter Wirkstoffe.", "en": "Prostate cancer: New hope thanks to old drugs." }, "short": "Prostatakrebs", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-12-15T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2017-04-01T02:00:00+02:00", "end_effective": "2017-03-31T02:00:00+02:00", "assignment": "2017-02-07T11:17:55+01:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-15", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4326, "title": { "de": "Wirkung von Laserakupunktur an Neugeborenen mit Neonatalem Entzugssyndrom(NAS)", "en": "Impact on laseracupuncture in newborns with neonatal abstinence syndrom" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-02-01T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2016-03-31T02:00:00+02:00", "end_effective": "2016-03-31T02:00:00+02:00", "assignment": "2016-02-24T13:42:31+01:00", "program": null, "subprogram": null, "organization": 14094, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4233, "title": { "de": "Die Rolle des Polyamin-Metabolismus in der T-Zell Immunologie bei Patienten mit Rheumatoider Arthritis", "en": "The role of polyamines for T-cell immunology in Rheumatoid Arthritis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-02-01T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2017-01-01T01:00:00+01:00", "end_effective": "2017-06-30T02:00:00+02:00", "assignment": "2016-01-18T11:20:00+01:00", "program": null, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 78952, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 87 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4233-78952-10" ] }, { "id": 4252, "title": { "de": "Zelluläre und molekulare Mechanismen der langen nichtkodierenden\r\nRNA LINC470 beim Kolorektalen Karzinom", "en": "Cellular and molecular mechanisms of the long non-coding RNA\r\nLINC470 in colorectal carcinogenesis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-02-01T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2017-01-31T01:00:00+01:00", "end_effective": "2017-12-31T01:00:00+01:00", "assignment": "2016-01-27T13:58:49+01:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 66005, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4252-66005-10" ] }, { "id": 4312, "title": { "de": "Analyse falsch positiver ß-D-Glucan-Werte nach Verabreichung von intravenösen Immunglobulin-Präparaten und anderen Blutprodukten", "en": "False positive ß-D-Glucan levels after intravenous administration of immunoglobuline preparations and other blodd products" }, "short": "BDG nach IVIG", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-03-01T01:00:00+01:00", "begin_effective": "2016-03-01T01:00:00+01:00", "end_planned": "2018-02-28T01:00:00+01:00", "end_effective": "2018-02-28T01:00:00+01:00", "assignment": "2016-02-12T12:12:08+01:00", "program": null, "subprogram": null, "organization": 14092, "category": 10, "type": 10, "partner_function": 4, "manager": 56810, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4312-56810-10" ] }, { "id": 4773, "title": { "de": "DK \"Molecular Fundamentals of Inflammation\" - Koordination (2. Förderperiode)", "en": "DK \"Molecular Fundamentals of Inflammation\" - Koordination (2. funding periode)" }, "short": "DK-MOLIN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-03-01T01:00:00+01:00", "begin_effective": "2016-03-01T01:00:00+01:00", "end_planned": "2020-02-29T01:00:00+01:00", "end_effective": "2021-06-30T02:00:00+02:00", "assignment": "2017-01-01T13:19:09+01:00", "program": 66, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 1, "manager": 51756, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1241", "ethics_committee": null, "edudract_number": null, "persons": [ "4773-51756-10" ] }, { "id": 4710, "title": { "de": "Mikrobiom bei Schizophrenie", "en": "Microbiome in Schizophrenia " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-01T02:00:00+02:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2017-10-01T02:00:00+02:00", "end_effective": "2017-10-01T02:00:00+02:00", "assignment": "2016-11-29T12:48:26+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4351, "title": { "de": "Suche nach molekularen Veränderungen im Myelosarkom", "en": "Screening for molecular aberrations in myeloid sarcoma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-15T02:00:00+02:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2017-04-15T02:00:00+02:00", "end_effective": "2017-04-15T02:00:00+02:00", "assignment": "2016-03-09T11:08:16+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 57402, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 423 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4351-57402-10", "4351-77371-12", "4351-94596-12", "4351-97430-12" ] }, { "id": 4257, "title": { "de": "Cardiotoxicity of Targeted Anti-Cancer Therapies", "en": "Cardiotoxicity of Targeted Anti-Cancer Therapies" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-01T02:00:00+02:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2018-03-31T02:00:00+02:00", "end_effective": "2025-06-30T02:00:00+02:00", "assignment": "2016-01-28T12:57:10+01:00", "program": null, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 58906, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 468 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4257-58906-10", "4257-98851-12", "4257-99984-12", "4257-104482-12" ] }, { "id": 4528, "title": { "de": "Mangelenernährung bei älteren Personen - Wissensforum", "en": "Malnutrition in the Elderly knowledge hub" }, "short": "MaNuEL", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-03-01T01:00:00+01:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2018-03-01T01:00:00+01:00", "end_effective": "2020-01-31T01:00:00+01:00", "assignment": "2016-07-20T15:39:35+02:00", "program": 90, "subprogram": null, "organization": 14509, "category": 10, "type": 10, "partner_function": 2, "manager": null, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 25 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4358, "title": { "de": "Ganzheitlicher Omics Zugang zur Allergischen Rhinitis", "en": "Holistic Omics approach to Allergic Rhinitis" }, "short": "Holistic Omics approach", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-01T02:00:00+02:00", "begin_effective": "2016-04-01T02:00:00+02:00", "end_planned": "2016-09-30T02:00:00+02:00", "end_effective": "2016-09-30T02:00:00+02:00", "assignment": "2016-03-14T14:45:03+01:00", "program": 103, "subprogram": null, "organization": 14066, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1824 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4350, "title": { "de": "Analyse von durch RAS Mutationen verursachten Genexpressionsmustern in einem murinen in vivo Modell der akuten myeloischen Leukämie", "en": "Analysis of gene expression profiles in a RAS-induced murine in vivo model of leukemia" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-04-15T02:00:00+02:00", "begin_effective": "2016-04-15T02:00:00+02:00", "end_planned": "2017-04-15T02:00:00+02:00", "end_effective": "2017-04-15T02:00:00+02:00", "assignment": "2016-03-09T11:07:13+01:00", "program": null, "subprogram": null, "organization": 14082, "category": 10, "type": 10, "partner_function": 4, "manager": 57402, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 423 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4350-57402-10", "4350-77371-12", "4350-94596-12", "4350-97430-12" ] }, { "id": 4432, "title": { "de": "Aufbau und Etablierung einer Biobank von humanem Stimmlippen-Gewebe.", "en": "Establishing a bio-bank of human vocal fold tissue." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-05-01T02:00:00+02:00", "begin_effective": "2016-05-01T02:00:00+02:00", "end_planned": "2018-04-30T02:00:00+02:00", "end_effective": "2018-04-30T02:00:00+02:00", "assignment": "2016-05-10T10:45:16+02:00", "program": null, "subprogram": null, "organization": 14068, "category": 10, "type": 10, "partner_function": 4, "manager": 50670, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4432-50670-10" ] }, { "id": 4439, "title": { "de": "Investigation of the cooperative function of Runx2 and Runx3 in regulating endochondral ossification", "en": "Investigation of the cooperative function of Runx2 and Runx3 in regulating endochondral ossification" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-05-01T02:00:00+02:00", "begin_effective": "2016-05-01T02:00:00+02:00", "end_planned": "2016-10-31T01:00:00+01:00", "end_effective": "2017-01-31T01:00:00+01:00", "assignment": "2016-05-11T14:38:12+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4220, "title": { "de": "Phospholipide und deren Rezeptoren in Erkrankungen des Kolons", "en": "Phospholipids and their receptors in diseases of the colon" }, "short": null, "url": null, "abstract": { "de": "Phospholipide und deren Rezeptoren: mögliche Rolle in entzündlichen Darmerkrankungen und im Dickdarmkrebs \r\nLipidmoleküle sind nicht nur wichtige Spieler im Energiestoffwechsel, sondern dienen auch als Botenstoffe zur Signalübertragung. Mehrere neue Arten solcher Lipidmoleküle, welche die Funktion von Krebszellen beeinflussen können, wurden in den letzten Jahren entdeckt. Unter ihnen befinden sich die sogenannten Endocannabinoide, die ähnliche Wirkung haben wie die Inhaltsstoffe von Cannabis sativa, aber im Organismus selbst gebildet werden. Diese Lipide sind Botenstoffe an Krebszellen, wo sie an Rezeptoren binden und die Funktion der Zellen beeinflussen.\r\nIm vorliegenden Projekt wollen wir einen sogenannten atypischen Cannabinoid Rezeptor mit dem Namen GPR55, der an Dickdarmkrebszellen vorkommt, untersuchen. Dieser Rezeptor besitzt als aktivierenden Botenstoff nicht nur Endocannabinoide, sondern auch ein Phospholipidmolekül, genannt LPI (Lysophophatidylinositol). LPI und GPR55 bilden zusammen eine Achse, von der man glaubt, dass sie eine treibende Rolle im Dickdarmkrebs und in entzündlichen Darmerkrankungen spielt. Diese Hypothese wird durch die Tatsache untermauert, dass GPR55 sowohl in Dickdarmkrebszellen als auch im gesunden Darm vorhanden ist und in experimentellen Modellen die Entzündung und das Krebswachstum fördert. Zur Klärung der Frage, ob diese molekulare Achse auch in Darmentzündungen und im Dickdarmkrebs des Menschen Bedeutung hat, wird der Gehalt an GPR55 Rezeptoren im Tumorgewebe von Kolonkarzinompatienten und in Darmbiopsien von Patienten mit entzündlichen Darmerkrankungen mittels geeigneten biochemischen und histologischen Methoden nachgewiesen. LPI wird im Serum mittels hochauflösender Massenspektrometrie gemessen. \r\nDie wenig erforschte Rolle von GPR55 in diesen Erkrankungen wird in diesem Projekt erstmals in humanen Proben untersucht. Es wird vermutet, dass GPR55 als Bestandteil des Endocannabinoidsystems an wichtigen Schaltstellen zur Entstehung dieser Erkrankungen sitzt. Diese Tatsache macht GPR55 zu einem wichtigen Angriffspunkt einer pharmakologischen Therapie. Schließlich wird in diesem Projekt auch die Möglichkeit erforscht, ob LPI als Biomarker zur Bestimmung dieser Krankheiten geeignet ist.\r\n", "en": null }, "begin_planned": "2015-10-01T02:00:00+02:00", "begin_effective": "2016-05-01T02:00:00+02:00", "end_planned": "2018-09-30T02:00:00+02:00", "end_effective": "2019-10-31T01:00:00+01:00", "assignment": "2016-01-11T13:59:08+01:00", "program": 108, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 56687, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI521", "ethics_committee": null, "edudract_number": null, "persons": [ "4220-56687-10" ] }, { "id": 4594, "title": { "de": "DK \"Molecular Fundamentals of Inflamation\" (2. Förderperiode)", "en": "DK \"Molecular Fundamentals of Inflamation\" (2. funding period)" }, "short": "DK-MOLIN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-10-01T02:00:00+02:00", "begin_effective": "2016-05-01T02:00:00+02:00", "end_planned": "2020-09-30T02:00:00+02:00", "end_effective": "2020-04-30T02:00:00+02:00", "assignment": "2016-09-06T10:45:26+02:00", "program": 66, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 2, "manager": 51529, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "W1241", "ethics_committee": null, "edudract_number": null, "persons": [ "4594-71386-12", "4594-77692-12", "4594-96374-12", "4594-51529-10" ] }, { "id": 4506, "title": { "de": "Dermal open flow microperfusion for the assessment of cytokine levels in thermal burns", "en": "Dermal open flow microperfusion for the assessment of cytokine levels in thermal burns" }, "short": "Dermal open flow microperfusion ", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-05-01T02:00:00+02:00", "begin_effective": "2016-05-01T02:00:00+02:00", "end_planned": "2018-04-30T02:00:00+02:00", "end_effective": "2018-04-30T02:00:00+02:00", "assignment": "2016-07-08T14:56:46+02:00", "program": null, "subprogram": null, "organization": 14076, "category": 10, "type": 10, "partner_function": 4, "manager": 80111, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1886 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4506-80111-10" ] }, { "id": 4141, "title": { "de": "Verbesserung der Studiendesigns von Beobachtungsstudien bei Infektionskrankheiten mittels mathematischer Modelle", "en": "Enhancing observational study designs of infectious disease surveys using mathematical modelling techniques" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-05-01T02:00:00+02:00", "begin_effective": "2016-05-01T02:00:00+02:00", "end_planned": "2016-07-31T02:00:00+02:00", "end_effective": "2016-07-31T02:00:00+02:00", "assignment": "2015-11-05T13:28:54+01:00", "program": null, "subprogram": null, "organization": 14026, "category": 10, "type": 10, "partner_function": 4, "manager": 83644, "contact": null, "status": 2, "research": 5, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4141-83644-10" ] } ] }