Project List
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GET /v1/research/project/?format=api&offset=1000&ordering=-end_effective
{ "count": 2265, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=1020&ordering=-end_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=980&ordering=-end_effective", "results": [ { "id": 5615, "title": { "de": "Kleinkinder in der digitalen Welt", "en": "Digital childhood" }, "short": "KiD", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-10-01T02:00:00+02:00", "begin_effective": "2018-12-01T01:00:00+01:00", "end_planned": "2020-09-30T02:00:00+02:00", "end_effective": "2021-05-31T02:00:00+02:00", "assignment": "2019-01-15T11:38:22+01:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 1, "manager": 64295, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 55 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5615-64295-10" ] }, { "id": 5817, "title": { "de": "Etablierung von Methoden zur Quantifizierung des Melaningehalts und des Melanocortin- 1-Rezeptors (MC1R) in humanen Melanomzelllinien MUG-Mel1, MUG-Mel2 und WM164", "en": "Establishment of methods for quantification of melanin amount and melanocortin- 1 receptor (MC1R) in human melanoma cell lines MUG-Mel1, MUG-Mel2 and WM164" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-06-01T02:00:00+02:00", "begin_effective": "2019-06-01T02:00:00+02:00", "end_planned": "2020-05-31T02:00:00+02:00", "end_effective": "2021-05-31T02:00:00+02:00", "assignment": "2019-06-05T12:05:36+02:00", "program": null, "subprogram": null, "organization": 28393, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5639, "title": { "de": "Mikrobiomveränderungen als Indikator für einen steroid-refraktären Verlauf bei Colitis ulzerosa\r\n\r\n\r\n", "en": "Study investigating if specific fecal microbiota alterations can predict a refractory disease course to standard steroid therapy in patients with active ulcerative colitis." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-01-01T01:00:00+01:00", "begin_effective": "2019-01-01T01:00:00+01:00", "end_planned": "2020-12-31T01:00:00+01:00", "end_effective": "2021-05-31T02:00:00+02:00", "assignment": "2019-01-24T09:45:52+01:00", "program": null, "subprogram": null, "organization": 14081, "category": 10, "type": 10, "partner_function": 1, "manager": 53167, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": "17936", "ethics_committee": null, "edudract_number": null, "persons": [ "5639-53167-10" ] }, { "id": 5581, "title": { "de": "Visuelle erweiterte Realität zur räumliche Zuordnung", "en": "Visual Augmented Reality Assistant for Spatial Mapping" }, "short": "VizARd", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-11-01T01:00:00+01:00", "begin_effective": "2018-11-01T01:00:00+01:00", "end_planned": "2020-10-31T01:00:00+01:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2018-12-11T12:25:14+01:00", "program": null, "subprogram": null, "organization": 14054, "category": 10, "type": 10, "partner_function": 2, "manager": 57389, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "867536", "ethics_committee": null, "edudract_number": null, "persons": [ "5581-57389-10" ] }, { "id": 6408, "title": { "de": "Psychosoziale Auswirkungen der SARS-CoV-2 Pandemie auf MitarbeiterInnen der Landeskrankenhäuser in der Steiermark", "en": "Psychosocial consequences of SARS-CoV-2 on individuals working in hospitals in styria" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2021-01-13T11:49:13+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 50654, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6408-50654-10" ] }, { "id": 4597, "title": { "de": "DK \"Molecular Fundamentals of Inflammation (2. Förderperiode)", "en": "DK \"Molecular Fundamentals of Inflammation (2. funding period)" }, "short": "DK-MOLIN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-10-01T02:00:00+02:00", "begin_effective": "2016-10-01T02:00:00+02:00", "end_planned": "2020-09-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2016-09-06T10:57:46+02:00", "program": 66, "subprogram": null, "organization": 14080, "category": 10, "type": 10, "partner_function": 4, "manager": 51809, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4597-98005-12", "4597-51809-10", "4597-104611-12" ] }, { "id": 6476, "title": { "de": "Cell culture system for antiviral testing", "en": "Cell culture system for antiviral testing" }, "short": "WP 91011", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-05-01T02:00:00+02:00", "begin_effective": "2020-05-01T02:00:00+02:00", "end_planned": "2021-04-30T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2021-03-03T15:30:32+01:00", "program": null, "subprogram": null, "organization": 14020, "category": 10, "type": 10, "partner_function": 2, "manager": 51663, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6476-51663-10" ] }, { "id": 4962, "title": { "de": "Die Funktion des Enzyms Phosphatidylethanolamine N‐Methyltransferase (PEMT) für die Chylomicronen-Biosynthese. ", "en": "Establishment of in vitro models for primary mouse enterocytes to study chylomicron biosynthesis: Role of the enzyme phosphatidylethanolamine N‐methyltransferase (PEMT)" }, "short": "PEMT und Chylomicronen-Biosynthese", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-05-01T02:00:00+02:00", "end_planned": "2018-12-31T01:00:00+01:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2017-05-22T12:39:11+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 51817, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 25 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4962-51817-10" ] }, { "id": 5983, "title": { "de": "AHNAK das riesen Protein: Lokalisierung und Expression in humanen Chordom-Zelllinien", "en": "AHNAK the giant Protein: Localization and Expression in human Chordoma Cell Lines" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-01-01T01:00:00+01:00", "begin_effective": "2020-01-01T01:00:00+01:00", "end_planned": "2020-08-31T02:00:00+02:00", "end_effective": "2021-04-30T02:00:00+02:00", "assignment": "2019-12-09T09:19:25+01:00", "program": null, "subprogram": null, "organization": 27477, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4191, "title": { "de": "Ultraschall basiertes Absetzen von Biologika bei Rheumatoider Arthritis", "en": "Ultrasound based withdrawal of biologics in Rheumatoid Arthritis" }, "short": "RA-BioStop", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-01-01T01:00:00+01:00", "begin_effective": "2016-01-01T01:00:00+01:00", "end_planned": "2019-03-31T01:00:00+01:00", "end_effective": "2021-03-31T02:00:00+02:00", "assignment": "2015-12-11T11:13:50+01:00", "program": 108, "subprogram": null, "organization": 14086, "category": 10, "type": 10, "partner_function": 4, "manager": 66227, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "KLI514", "ethics_committee": null, "edudract_number": null, "persons": [ "4191-53560-12", "4191-78952-12", "4191-100419-12", "4191-100821-12", "4191-105947-12", "4191-111407-12", "4191-66227-10" ] }, { "id": 4865, "title": { "de": "Kalziumdomäne in Orai1 reguliert NFAT abhängige Gene", "en": "Calcium domain in Orai1 regulates NFAT dependent genes" }, "short": null, "url": null, "abstract": { "de": "Kalziumdomäne in Orai1 reguliert Gene im Immunsystem\r\nKalzium steuert das Immunsystem vielseitig, etwa indem es spezielle Gene aktiviert. Diese Gen-regulation führt zur raschen Teilung von Immunzellen oder zur Abwehr eindringender Bakterien. Für diese zellulären Prozesse strömt Kalzium über eine Pore, den sogenannte Ionenkanal Orai1, in die Immunzelle ein. Orai1 wirkt somit wie ein Schalter, den die Immunzelle entweder oszillatorisch oder langanhaltend öffnen kann. Mutationen in Orai1 können zu schweren Immunkrankheiten führen. In diesem Projekt möchten Dr. Rainer Schindl und seine Mitarbeiter herausfinden, wie die Genregulation der Immunzellen durch molekulare Strukturen des Kalziumtransports gesteuert wird. In Vorexperimenten konnten wir bereits mit Supercomputern eine Bindung von Kalzium an den Ionenkanal Orai1 simulieren. Unsere Hypothese ist, dass diese Kalzium Bindedomäne den Kalzium Einstrom reguliert, und für die Genregulation von entscheidender Bedeutung ist. Zur experimentellen Untersuchung wird die Kalzium Bindestruktur genetisch verändert und mit dem ursprünglichen Orai1 Ionenkanal verglichen. Sowohl der Einstrom von Kalzium in die Zelle, die Aktivierung von Genen als auch die anschließende Produktion von Proteinen werden gemessen. Diese Methoden erlauben es eine mechanistische Verbindung von molekularen Orai1 Strukturen über Kalzium Transportwege bis hin zur Produktion von Proteinen herzustellen. Die Charakterisierung der Kalzium Bindestruktur im Orai1 Kanal verspricht fundamental neue Erkenntnisse über den Kalziumtransport in die Immunzelle. Die Regulation des Kalzium Einstroms wird klären wie Gene effizient aktiviert werden können.\r\n", "en": "Calcium domain in Orai1 regulates genes in the immune system\r\nCalcium is a main trigger for the immune system due to its regulation of gene expression. This signaling process controls both the proliferation of immune cells and the defense against bacteria. To mediate these cellular processes, calcium influx occurs via special pores, termed the Orai1 ion channel. Orai1 acts like a trigger that can be oscillatory or sustained opened by an immune cell. Mutations within Orai1 can result in severe immune diseases. Within this project, Dr. Rainer Schindl and his team aim to resolve which molecular structures are required for the calcium transport into immune cells and subsequent gene regulation. In preliminary experiments, we used super computers to simulate the binding of calcium with the ion channel Orai1. We hypothesize that this calcium binding domain is crucial for gene regulation. Hence the calcium binding structure will be genetically modified and compared experimentally with the function of the original Orai1 ion channel. We will record the influx of calcium into the cell, the activation of genes and the production of proteins. These methods allow to mechanistically link the molecular Orai1 structures, with calcium transport pathways and the production of proteins. The characterization of Orai1 calcium binding structure aims to provide fundamental insight into calcium transport in immune cells. Regulation of calcium influx will determine how genes are activated efficiently. \r\n" }, "begin_planned": "2017-03-01T01:00:00+01:00", "begin_effective": "2017-03-01T01:00:00+01:00", "end_planned": "2020-02-29T01:00:00+01:00", "end_effective": "2021-03-31T02:00:00+02:00", "assignment": "2017-03-02T14:37:06+01:00", "program": 72, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 98848, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 28701", "ethics_committee": null, "edudract_number": null, "persons": [ "4865-98848-10" ] }, { "id": 5222, "title": { "de": "Funktionelle Charakterisierung von neutrophilen Granulozyten im Lungenkarzinom\r\n", "en": "Functional characterization of tumor-associated neutrophils in non-small cell lung cancer\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-04-01T02:00:00+02:00", "begin_effective": "2018-04-01T02:00:00+02:00", "end_planned": "2021-02-28T01:00:00+01:00", "end_effective": "2021-03-31T02:00:00+02:00", "assignment": "2018-01-31T09:29:42+01:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 1, "manager": 60706, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 12 ], "funder_projectcode": "17584", "ethics_committee": null, "edudract_number": null, "persons": [ "5222-50777-12", "5222-60706-10" ] }, { "id": 4654, "title": { "de": "Einfluss adhärenter Blutplättchen auf den Zottentrophoblast", "en": "The role of adhering maternal platelets on villous trophoblast" }, "short": "Platelets and trophoblasts", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-03-01T01:00:00+01:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2020-02-28T01:00:00+01:00", "end_effective": "2021-03-31T02:00:00+02:00", "assignment": "2016-10-14T13:12:11+02:00", "program": 72, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 53232, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P29639", "ethics_committee": null, "edudract_number": null, "persons": [ "4654-53232-10" ] }, { "id": 4204, "title": { "de": "Gehirn Imaging, Kognition, Demenz und Next Generation Genomics: interdisziplinäre Forschung um Risiko und protektive Faktoren bei neurodegenerativen Erkrankungen zu identifizieren", "en": "BRain Imaging, cognition, Dementia and next generation GEnomics: a Transdisciplinary approach to search for risk and protective factors of neurodegenerative disease" }, "short": "BRIDGET", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-01-01T01:00:00+01:00", "begin_effective": "2015-12-01T01:00:00+01:00", "end_planned": "2018-12-31T01:00:00+01:00", "end_effective": "2021-03-31T02:00:00+02:00", "assignment": "2015-12-21T09:15:49+01:00", "program": null, "subprogram": "Joint Programme - Neurodegenerative Disease Research", "organization": 14013, "category": 10, "type": 10, "partner_function": 2, "manager": 51912, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "4204-51912-10" ] }, { "id": 6063, "title": { "de": "Oxidative Stressparameter bei Anorexia nervosa PatientInnen", "en": "Oxidative stress in anorexia nervosa patients" }, "short": "ILSD-AN", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-03-20T01:00:00+01:00", "begin_effective": "2020-03-01T01:00:00+01:00", "end_planned": "2021-03-20T01:00:00+01:00", "end_effective": "2021-02-28T01:00:00+01:00", "assignment": "2020-02-21T10:32:13+01:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 4, "manager": 84449, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6063-84449-10" ] }, { "id": 5723, "title": { "de": "Einfluss des Exposoms auf das humane Hautmikrobiom", "en": "Impact of the exposome on the human skin microbiome" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-03-01T01:00:00+01:00", "begin_effective": "2019-03-01T01:00:00+01:00", "end_planned": "2020-02-29T01:00:00+01:00", "end_effective": "2021-02-28T01:00:00+01:00", "assignment": "2019-03-07T13:25:39+01:00", "program": null, "subprogram": null, "organization": 14023, "category": 10, "type": 10, "partner_function": 4, "manager": 90021, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5723-90021-10" ] }, { "id": 5673, "title": { "de": "T-Zell-Telomer-Dynamik und Ansprechen auf Immun-Checkpoint-Inhibitor-Therapie bei Lungenkrebs", "en": "T-cell Telomere Dynamics and Immune Checkpoint Inhibitor Response in Lung Cancer\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-01-01T01:00:00+01:00", "begin_effective": "2019-01-01T01:00:00+01:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2021-02-28T01:00:00+01:00", "assignment": "2019-02-12T11:16:33+01:00", "program": null, "subprogram": null, "organization": 14028, "category": 10, "type": 10, "partner_function": 4, "manager": 50910, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1765 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5673-50910-10" ] }, { "id": 6065, "title": { "de": "Klinische und molekulargenetische Daten von Kindern und Jugendlichen mit spinalem Ependymomen", "en": "Clinical and molecular data of children and adolescents with spinal cord ependymoma" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-04-01T02:00:00+02:00", "begin_effective": "2020-04-01T02:00:00+02:00", "end_planned": "2020-09-01T02:00:00+02:00", "end_effective": "2021-02-28T01:00:00+01:00", "assignment": "2020-02-24T09:40:40+01:00", "program": null, "subprogram": null, "organization": 14092, "category": 10, "type": 10, "partner_function": 2, "manager": 51369, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1550 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6065-51369-10" ] }, { "id": 5044, "title": { "de": "Diabetes mellitus und assoziierte Risikofaktoren bei bipolarer Störung", "en": "Diabetes mellitus und associated risk factors in bipolar disorder" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-04-01T02:00:00+02:00", "begin_effective": "2017-09-01T02:00:00+02:00", "end_planned": "2018-04-01T02:00:00+02:00", "end_effective": "2021-02-28T01:00:00+01:00", "assignment": "2017-08-23T12:39:33+02:00", "program": null, "subprogram": null, "organization": 29444, "category": 10, "type": 10, "partner_function": 1, "manager": 79733, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5044-79733-10" ] }, { "id": 4593, "title": { "de": "Magnetische Eigenschaften weißer Gehirnsubstanz bei Multipler Sklerose Patienten", "en": "Magnetic Properties of Normal Appearing Brain White Matter in Multiple Sclerosis" }, "short": "QMTinMS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-07-01T02:00:00+02:00", "begin_effective": "2017-02-01T01:00:00+01:00", "end_planned": "2019-06-30T02:00:00+02:00", "end_effective": "2021-01-31T01:00:00+01:00", "assignment": "2016-09-06T10:24:56+02:00", "program": 64, "subprogram": "DACH", "organization": 14051, "category": 10, "type": 10, "partner_function": 4, "manager": 51279, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I3001", "ethics_committee": null, "edudract_number": null, "persons": [ "4593-51279-10" ] } ] }