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GET /v1/research/project/?format=api&offset=100&ordering=-begin_effective
{ "count": 2261, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=120&ordering=-begin_effective", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=80&ordering=-begin_effective", "results": [ { "id": 9045, "title": { "de": "Die Bedeutung von IL-36-Signalübertragung und angeborenen Immunzellen bei pustulösen Hauterkrankungen", "en": "The role of IL-36 signaling and innate immune cells in pustular skin diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-07-01T02:00:00+02:00", "begin_effective": "2025-07-01T02:00:00+02:00", "end_planned": "2027-06-30T02:00:00+02:00", "end_effective": "2027-06-30T02:00:00+02:00", "assignment": "2025-06-23T13:56:58+02:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 88082, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1983 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9045-88082-10" ] }, { "id": 9062, "title": { "de": "In-vitro-Untersuchung der ZX00-Implantate für die Bildung von Knorpelgewebe", "en": "In vitro investigation of the ZX00 implants for the cartilage tissue formation" }, "short": null, "url": null, "abstract": { "de": null, "en": "In children and adolescents, cartilage defects have significant impact on their quality of life due to impairment of joint function in older age. The refixation of loose cartilage, tissue engineering templates or refixation of cartilage after trauma are important to rescue the function of the knee joint. Consequently, the development of innovative techniques for fixation and the optimization of existing ones remain key priorities, driving extensive research efforts from basic science to clinical applications. In the last decade, magnesium (Mg)-based implants become promising alternatives in the orthopedic field because of its biocompatibility, good mechanical properties, biodegradability, and other functional properties. Our research group showed cartilage regeneration after putting an Mg-based screw through the joint surface and the growth plate in ovine model. Besides, tissue regeneration during degradation of the Mg-based screw did not lead to growth disturbances in comparison to titanium-based screws. However, the limited information about effects of Mg-based implants on chondrogenic differentiation, both in direct contact and as extract, point out the need for further investigations. Possible effects due to the alloying elements also need to be better understood. Therefore, this proposed study aims to investigate the potential effects of one of the most commonly used Mg-based implants, ZX00 alloy (Mg-Zn-Ca alloy) on cartilage tissue formation and provide a preliminary data for in vivo experiments.\r\n" }, "begin_planned": "2025-06-02T02:00:00+02:00", "begin_effective": "2025-07-01T02:00:00+02:00", "end_planned": "2026-06-01T02:00:00+02:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2025-06-30T11:23:18+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 4, "manager": 102252, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1566 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9062-102252-10" ] }, { "id": 9104, "title": { "de": "Wirkung von S. auf die Adipozyten–Makrophagen-Kommunikation im Lipödem", "en": "Effect of S. on the adipocyte-macrophage-crosstalk in lipedema" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-07-01T02:00:00+02:00", "begin_effective": "2025-07-01T02:00:00+02:00", "end_planned": "2026-06-30T02:00:00+02:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2025-07-28T16:29:26+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 90806, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9104-90806-10" ] }, { "id": 9091, "title": { "de": "Erforschung der zellulären Stressreaktion nach UV-Bestrahlung aus schonenden Hautbiopsien", "en": "Exploring cellular stress response of UV irradiation with gentle skin biopsy\r\n" }, "short": "GentleSkinBiopsie", "url": null, "abstract": { "de": "Hypothese\r\n\r\n Sanfte Harpera-Biopsien reichen für die Transkriptomik (genomweite Expressionsprofile) aus.\r\n 222 nm UVC desinfiziert die Haut effektiv mit weniger zellulären Stressreaktionen als nb-UVB-Phototherapie.\r\n\r\n\r\nAnsatz\r\n\r\n Transkriptomik von sanften Harpera-Biopsien messen und mit 3 mm Biopsien vergleichen.\r\n Zelluläre Stressreaktionen mit und ohne UVC- und UVB-Bestrahlung vergleichen.\r\n", "en": "Skin diseases affect up to 30% of the current population and many undergo a long diagnostic process, often with a 3 mm punch biopsy, leaving a small scar. The gentle, 0.2 mm tiny Harpera microbiopsy could be a scar-free alternative if suitable for transcriptomics. \r\nAnother challenge in dermatology is the cellular stress from nb-UVB irradiation, the first-line therapy for e.g. atopic dermatitis (AD). Here, 222 nm UVC could be a safer, yet as anti-microbial effective, alternative, thanks to low penetration depth of UVC. Studying the cellular stress response of UVC would bring it closer to clinical routine. \r\n\r\nHypothesis\r\n1.\tGentle Harpera biopsies suffice for transcriptomics (genome-wide expression profiles).\r\n2.\t222 nm UVC effectively disinfects skin with less cellular stress responses than nb-UVB phototherapy.\r\n\r\nApproach\r\n1.\tMeasure transcriptomics from gentle Harpera, benchmarking to 3 mm biopsies. \r\n2.\tCompare cellular stress responses with and without UVC and UVB irradiation.\r\n\r\nThe proof that gentle skin biopsies deliver reliable transcriptomics would revolutionize clinical and basic research, enabling longitudinal studies and expanding outreach to underserved, rural populations. Styria’s excellent teledermatology could be further improved with remote sampling. \r\nThe proof that UVC is safely anti-microbial is one more step towards routine use, enabling disinfection without resistances, benefiting a plethora of patients and ultimately reducing health care costs.\r\n" }, "begin_planned": "2025-07-01T02:00:00+02:00", "begin_effective": "2025-07-01T02:00:00+02:00", "end_planned": "2026-06-30T02:00:00+02:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2025-07-21T12:59:36+02:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 87663, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9091-87663-10" ] }, { "id": 9609, "title": { "de": "Ex-vivo-Untersuchung von Biglykan in Lungenschnitten", "en": "Ex-vivo investigation of biglycan in precision cut lung slices" }, "short": "BiLS", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-25T02:00:00+02:00", "begin_effective": "2025-06-25T02:00:00+02:00", "end_planned": "2026-06-25T02:00:00+02:00", "end_effective": "2026-06-25T02:00:00+02:00", "assignment": "2026-02-17T11:38:32+01:00", "program": null, "subprogram": null, "organization": 14006, "category": 10, "type": 10, "partner_function": 1, "manager": 114963, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 530 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9609-114963-10" ] }, { "id": 8844, "title": { "de": "Metabolomics für Empagliflozin nach Myokardinfarkt", "en": "Metabolomics for empagliflozin after myocardial infarction\r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2027-05-31T02:00:00+02:00", "end_effective": "2027-05-31T02:00:00+02:00", "assignment": "2025-05-13T10:38:24+02:00", "program": 108, "subprogram": null, "organization": 14083, "category": 10, "type": 10, "partner_function": 4, "manager": 59317, "contact": null, "status": 2, "research": 4, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "PAT3914524", "ethics_committee": null, "edudract_number": null, "persons": [ "8844-59317-10" ] }, { "id": 8929, "title": { "de": "Anatomisches Erbe: Unseren Vergangenheit digital bewahren, Unsere Zukunft sichern", "en": "ANATOMICAL LEGACY: DIGITALLY PRESERVING OUR PAST, SECURING OUR FUTURE" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-04-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2026-01-12T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-05-23T11:40:55+02:00", "program": 207, "subprogram": null, "organization": 14018, "category": 10, "type": 10, "partner_function": 1, "manager": 102804, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 20 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8929-97024-12", "8929-102804-10" ] }, { "id": 8609, "title": { "de": "Exogene eletrische und mechanische Stimulation durch eletronische Haut stimuliert die Zellprofileration der oralen Mundschleimhaut", "en": "Exogenous electrical and mechanical motion stimulation by using an electronic skin for support oral cell proliferation." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-02-01T01:00:00+01:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2028-01-31T01:00:00+01:00", "end_effective": "2028-05-31T02:00:00+02:00", "assignment": "2025-01-21T17:58:12+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 133140, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "ESP6372324", "ethics_committee": null, "edudract_number": null, "persons": [ "8609-133140-10" ] }, { "id": 8952, "title": { "de": "Partikeltherapie bei PatientInnen mit Sarkomen. Retrospektive, multizentrische Analyse des klinischen und onkologischen Outcomes in Österreich.", "en": "Particle therapy in patients with sarcoma. Retrospective, multicentre study of clinical and oncological outcomes in Austria." }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2025-05-31T02:00:00+02:00", "end_effective": "2026-11-30T01:00:00+01:00", "assignment": "2025-05-28T10:29:07+02:00", "program": null, "subprogram": null, "organization": 14052, "category": 10, "type": 10, "partner_function": 1, "manager": 95171, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1270 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8952-95171-10" ] }, { "id": 8917, "title": { "de": "Mastzellen als Trendsetter im Übergang von Immunantworten", "en": "Mast cells as trendsetters in the transition of immune responses" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2026-05-31T02:00:00+02:00", "end_effective": "2026-05-31T02:00:00+02:00", "assignment": "2025-05-22T12:13:41+02:00", "program": null, "subprogram": null, "organization": 14047, "category": 10, "type": 10, "partner_function": 4, "manager": 107955, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8917-107955-10" ] }, { "id": 8879, "title": { "de": "Wirkung von Tirzepatid und Inkretinen auf den Stoffwechsel von Endothelzellen", "en": "Effect of tirzepatide and incretins on endothelial cell metabolism" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2026-12-31T01:00:00+01:00", "end_effective": "2026-12-31T01:00:00+01:00", "assignment": "2025-05-20T14:36:13+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 77116, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 894 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8879-77116-10" ] }, { "id": 9577, "title": { "de": "Er: YAG-Laser vs. rotierende Instrumente – Einfluss\r\nder Erfahrung auf Effizienz, Oberflächenqualität und\r\nPräferenz bei der Entfernung von Veneers", "en": "Er: YAG laser vs. rotary instruments - influence\r\nof experience on efficiency, surface quality and\r\npreference when removing veneers" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2026-12-01T01:00:00+01:00", "end_effective": "2026-12-01T01:00:00+01:00", "assignment": "2026-02-02T12:41:25+01:00", "program": null, "subprogram": null, "organization": 14111, "category": 10, "type": 10, "partner_function": 1, "manager": 126234, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2591 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9577-126234-10" ] }, { "id": 8716, "title": { "de": "p53-abhängiges hepatozelluläres Karzinom-Zellschicksal bei Nährstoffrestriktion", "en": "p53-dependent hepatocellular carcinoma cell fate upon nutrient restriction" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2027-06-30T02:00:00+02:00", "end_effective": "2027-06-30T02:00:00+02:00", "assignment": "2025-03-10T12:16:14+01:00", "program": null, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 99151, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8716-99151-10" ] }, { "id": 8839, "title": { "de": "In vivo- Kompetition von AML-Zellen, die verschiedene TP53 -Aberrationen aufweisen", "en": "In vivo competition of AML cells harboring different TP53 aberrations " }, "short": "Tp53 in AML", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-06-01T02:00:00+02:00", "end_planned": "2026-06-01T02:00:00+02:00", "end_effective": "2026-06-01T02:00:00+02:00", "assignment": "2025-05-09T12:43:44+02:00", "program": null, "subprogram": null, "organization": 14085, "category": 10, "type": 10, "partner_function": 4, "manager": 101484, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 423 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8839-101484-10" ] }, { "id": 9071, "title": { "de": "Effektivität und Sicherheit in der mikroinvasiven\r\n Glaukomchirurgie – MINIject versus Hydrus Microstent", "en": "Effectiveness and safety in microinvasive glaucoma surgery – MINIject versus Hydrus Microstent" }, "short": "MINHY", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-03-10T01:00:00+01:00", "begin_effective": "2025-05-29T02:00:00+02:00", "end_planned": "2031-03-10T01:00:00+01:00", "end_effective": "2027-05-29T02:00:00+02:00", "assignment": "2025-07-07T11:35:54+02:00", "program": null, "subprogram": null, "organization": 14043, "category": 10, "type": 10, "partner_function": 1, "manager": 117341, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 938 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "9071-117341-10" ] }, { "id": 8798, "title": { "de": "Mitochondriale Dysfunktion in der Endometriose", "en": "The Role of Mitochondrial Dysfunction in the Pathogenesis of Endometriosis" }, "short": "Mito-Endometriosis", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-05-01T02:00:00+02:00", "begin_effective": "2025-05-01T02:00:00+02:00", "end_planned": "2026-04-30T02:00:00+02:00", "end_effective": "2026-04-30T02:00:00+02:00", "assignment": "2025-04-23T11:20:36+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 116510, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8798-116510-10" ] }, { "id": 8752, "title": { "de": "Aufbau der Grazer Ambulanz für Riech- und Schmeckstörungen", "en": "Establishment of the Graz Clinic for Smell and Taste Disorders" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-06-01T02:00:00+02:00", "begin_effective": "2025-05-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2025-12-31T01:00:00+01:00", "assignment": "2025-04-01T19:13:16+02:00", "program": null, "subprogram": null, "organization": 14066, "category": 10, "type": 10, "partner_function": 4, "manager": 89704, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 457 ], "funder_projectcode": "FIF-A 16-0020/2025-0001", "ethics_committee": null, "edudract_number": null, "persons": [ "8752-89704-10" ] }, { "id": 8783, "title": { "de": "N-Acylethanolaminsäureamid-Hydrolase (NAAA) : ein attraktives Target für Asthma\r\nBehandlung ", "en": "N-acylethanolamine acid amidase (NAAA): an appealing target for asthma\r\ntreatment" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-05-01T02:00:00+02:00", "begin_effective": "2025-05-01T02:00:00+02:00", "end_planned": "2026-05-01T02:00:00+02:00", "end_effective": "2026-05-01T02:00:00+02:00", "assignment": "2025-04-15T18:25:53+02:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 116746, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8783-116746-10" ] }, { "id": 8799, "title": { "de": "Trauma & Herz", "en": "Trauma & Heart" }, "short": "Trauma & Herz", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-05-01T02:00:00+02:00", "begin_effective": "2025-05-01T02:00:00+02:00", "end_planned": "2026-04-30T02:00:00+02:00", "end_effective": "2026-06-30T02:00:00+02:00", "assignment": "2025-04-23T13:51:00+02:00", "program": null, "subprogram": null, "organization": 29447, "category": 10, "type": 10, "partner_function": 4, "manager": 75522, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2471 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8799-75522-10" ] }, { "id": 8710, "title": { "de": "Klinisch-immunologische Charakterisierung der Chronischen Rhinosinusitis", "en": "Clinical-immunological characterization of chronic rhinosinusitis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2025-05-01T02:00:00+02:00", "begin_effective": "2025-05-01T02:00:00+02:00", "end_planned": "2025-12-31T01:00:00+01:00", "end_effective": "2027-12-31T01:00:00+01:00", "assignment": "2025-03-06T10:01:42+01:00", "program": null, "subprogram": null, "organization": 14066, "category": 10, "type": 10, "partner_function": 4, "manager": 89704, "contact": null, "status": 2, "research": 10, "grant": 10, "event": null, "study": 12, "language": null, "funders": [ 457 ], "funder_projectcode": "FIF-A 16-0479/2024-0002", "ethics_committee": null, "edudract_number": null, "persons": [ "8710-89704-10" ] } ] }