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GET /v1/research/project/?format=api&offset=100
{ "count": 2194, "next": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=120", "previous": "https://api-test.medunigraz.at/v1/research/project/?format=api&limit=20&offset=80", "results": [ { "id": 4967, "title": { "de": "Der Einfluss von Angiotensin II auf das plazentale Fraktalkin", "en": "The role of angiotensin II on placental fractalkine" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-01-01T01:00:00+01:00", "begin_effective": "2017-10-01T02:00:00+02:00", "end_planned": "2019-12-31T01:00:00+01:00", "end_effective": "2021-09-30T02:00:00+02:00", "assignment": "2017-05-24T14:53:01+02:00", "program": 71, "subprogram": "DACH", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 53232, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "I 3304", "ethics_committee": null, "edudract_number": null, "persons": [ "4967-53232-10" ] }, { "id": 5347, "title": { "de": "Effizienter Mitochondrien-Transfer", "en": "Effizienter Mitochondrien-Transfer" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2018-04-01T02:00:00+02:00", "begin_effective": "2018-04-01T02:00:00+02:00", "end_planned": "2019-03-31T01:00:00+01:00", "end_effective": "2022-12-31T01:00:00+01:00", "assignment": "2018-04-18T12:34:44+02:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-02", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 4653, "title": { "de": "Flexibilität in der Organforschung", "en": "Flexibility in Organ Research" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-10-01T02:00:00+02:00", "begin_effective": "2017-02-01T01:00:00+01:00", "end_planned": "2019-09-30T02:00:00+02:00", "end_effective": "2021-01-31T01:00:00+01:00", "assignment": "2016-10-14T13:09:27+02:00", "program": 64, "subprogram": "Partnership in Research", "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 76930, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9, 23 ], "funder_projectcode": "PIR00007", "ethics_committee": null, "edudract_number": null, "persons": [ "4653-50394-12", "4653-76930-10", "4653-51718-12", "4653-128875-12" ] }, { "id": 4847, "title": { "de": "Hochauflösende In-silico Modelle der Gesamten Herzfunktion", "en": "High-resolution In Silico Models of Total Heart Function" }, "short": "InsiliCardio", "url": null, "abstract": { "de": "Fortschritte bei der Entwicklung von tomographischen Verfahren ermöglichen in beispielloser Weise die Anatomie des Herzens abzubilden. Allerdings hatten diese Technologien bisher einen relativ geringen Einfluss auf die Entwicklung von medizinischen Implantaten oder die Verbesserung von klinischen Behandlungsmethoden. \r\nDer Einsatz von bildgebenden Verfahren zur Extraktion von wichtigen funktionellen Informationen und der Kopplung von Bildinformationen mit physiologischen Aspekten, die nicht durch Bildgebung allein verstanden werden können, stellt eine große Herausforderung dar. In silico Modelle, also computerunterstützte Simulationen, bergen enormes Potenzial zur Bewältigung dieser Herausforderungen und können zu einem besseren Verständnis der Herzfunktion, sei es im gesunden oder auch im erkrankten Zustand, führen. Ein entscheidender Vorteil ist hierbei die Möglichkeit diagnostische und therapeutische Methoden zu optimieren ohne dabei Patienten zusätzlichen Risiken oder Schmerzen auszusetzen. In silico Experimente können somit bei der Untersuchung von klinisch relevanten Problemen, wie zum Beispiel Herzklappenchirurgie, Ballon-Angioplastie oder Stenting, äußerst hilfreich sein. \r\nDie Herzfunktion ergibt sich aus der Interaktion verschiedener Physiken, unter anderem der Elektrophysiologie, der Strukturmechanik und der Strömungsmechanik. Während die beteiligten Physiken klar bidirektional wechselwirken, werden sie in praktisch allen Studien isoliert betrachtet. Dies ist zu einem guten Teil auf die Komplexität von Multiphysik-Modellen und den Schwierigkeiten, die bei der Entwicklung von modernen numerischen Methoden und deren effizienten Implementierung auf modernen Rechnerarchitekturen auftauchen, zurückzuführen. Die Bewältigung dieser Herausforderungen ist das zentrale Themas dieses Projektes und die Durchführung setzt auf die Kombination der Expertisen der Antragsteller: Christoph Augustin und Gernot Plank in der Modellierung der Elektrophysiologie und der Strukturmechanik und Shawn Shadden in der Computermodellierung des Blutflusses. \r\nDieses ambitionierte Unterfangen geht weit über den aktuellen Stand der Technik hinaus. Kombinierte Modelle von Herz und Blutgefäßen ermöglichen die Berechnung von natürlichen Randbedingungen für die Simulation des Blutflusses und das Studium von Rückkopplungsmechanismen die die Pumpleistung des Herzens beeinflussen können. Im Endeffekt wird dieses Modell eines der modernsten Werkzeuge der Grundlagenforschung sein, das einen mechanistischen Einblick in die Herzpumpfunktion gewährt. Von wesentlicher Bedeutung ist in diesem Kontext auch die Überprüfung, Parametrisierung und Validierung dieses Modells mit klinischen Datensätzen, die von klinischen Partnern zur Verfügung gestellt werden. \r\nDas Ziel dieser Forschung ist ein innovatives Multiphysik-Computermodell der gesamten Herzfunktion um eine biophysikalisch detaillierte und bidirektional gekoppelte Erforschung der elektromechanischen Funktion des Herzens im gesunden wie im kranken Zustand zu ermöglichen.", "en": "Advances in medical imaging have enabled unprecedented ability to image cardiac anatomy and function. So far these technologies have had relatively modest clinical impact as the analysis of such rich multi-modal datasets has proven challenging. In silico models hold vast potential to better harness such datasets by enabling their integration into quantitative frameworks that can aid in gaining better mechanistic insight into cardiac function in health and disease, and thus paving the way towards optimal therapeutic strategies.\r\nOur objective is to develop the most advanced biophysically detailed in-silico model of total electro-mechano-fluidic function of the heart. This model will be parametrized, verified and used to study cause-effect relationships between flow and pressure and their impact upon pumping performance. A novel set of features such as combined models of both heart and attached outflow vessels and the computational efficiency will provide a unique platform for translational research.\r\nThis ambitious endeavor is feasible only by combining the expertise of the applicant in modeling soft tissue mechanics and his supervisors in modeling electrophysiology (Gernot Plank, MUG) and blood flow (Shawn Shadden, UC Berkeley). Clinical input and datasets for model parametrization and validation are provided by Titus Kühne (DHZ Berlin) and by clinical collaborators of Prof. Shadden at UCSF. During the return-phase, the applicant will use the infrastructure of Prof. Plank’s lab and the large network of academic and industrial collaborations as an incubator for building up his own research group in computational hemodynamics. This is ideal in many regards, as the expertise of the applicant's group will be entirely orthogonal to the expertise in Prof. Plank's lab, thus promoting a fast pathway towards full indepence, and core expertise necessary for further developing and maintaining a highly complex computing environment is synergistically shared between the labs." }, "begin_planned": "2017-06-01T02:00:00+02:00", "begin_effective": "2017-03-01T01:00:00+01:00", "end_planned": "2020-05-31T02:00:00+02:00", "end_effective": "2019-08-31T02:00:00+02:00", "assignment": "2017-02-20T09:41:41+01:00", "program": 109, "subprogram": null, "organization": 14011, "category": 10, "type": 10, "partner_function": 4, "manager": 79791, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "750835", "ethics_committee": null, "edudract_number": null, "persons": [ "4847-79791-10" ] }, { "id": 5019, "title": { "de": "Die Rolle der 15-Prostaglandindehydrogenase in der idiopathischen pulmonalen Fibrose", "en": "The Role of 15-Prostaglandindehydrogenase in Idiopathic Pulmonary Fibrosis" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2017-08-01T02:00:00+02:00", "begin_effective": "2017-08-01T02:00:00+02:00", "end_planned": "2020-07-31T02:00:00+02:00", "end_effective": "2020-07-31T02:00:00+02:00", "assignment": "2017-07-31T13:29:12+02:00", "program": 116, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 85658, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 15 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5019-85658-10" ] }, { "id": 6340, "title": { "de": "Maßnahmen zur Attraktivierung der Allgemeinmedizin 2020-2021\r\n", "en": "Measures to increase the attractiveness of family medicine 2020-2021" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2020-11-01T01:00:00+01:00", "begin_effective": "2020-11-01T01:00:00+01:00", "end_planned": "2021-12-31T01:00:00+01:00", "end_effective": "2021-12-31T01:00:00+01:00", "assignment": "2020-11-24T12:35:08+01:00", "program": null, "subprogram": null, "organization": 27964, "category": 10, "type": 10, "partner_function": 4, "manager": 51098, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2160 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "6340-51098-10" ] }, { "id": 5927, "title": { "de": "Maßnahmen zur \r\nAttraktivierung der Allgemeinmedizin \r\n", "en": "Maßnahmen zur \r\nAttraktivierung der Allgemeinmedizin \r\n" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-11-01T01:00:00+01:00", "begin_effective": "2019-11-01T01:00:00+01:00", "end_planned": "2020-10-31T01:00:00+01:00", "end_effective": "2020-10-31T01:00:00+01:00", "assignment": "2019-10-16T10:46:08+02:00", "program": null, "subprogram": null, "organization": 27964, "category": 10, "type": 10, "partner_function": 4, "manager": 51098, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 2160 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "5927-51098-10" ] }, { "id": 3164, "title": { "de": "NANOpartikel in geklonten Zellen", "en": "NANOparticles in cloned cells" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-01-01T01:00:00+01:00", "end_planned": "2013-11-30T01:00:00+01:00", "end_effective": "2013-12-30T01:00:00+01:00", "assignment": "2013-02-05T12:17:18+01:00", "program": null, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 51158, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3164-51158-10" ] }, { "id": 8121, "title": { "de": "Modelling Reproductive Failure with Endometrium-On-A-Chip, acib Projekt ID 98.311 ", "en": "Modelling Reproductive Failure with Endometrium-On-A-Chip, acib Projekt ID 98.311 " }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2024-01-01T01:00:00+01:00", "begin_effective": "2024-01-01T01:00:00+01:00", "end_planned": "2028-12-31T01:00:00+01:00", "end_effective": "2028-12-31T01:00:00+01:00", "assignment": "2024-03-28T10:01:53+01:00", "program": 94, "subprogram": null, "organization": 14017, "category": 10, "type": 10, "partner_function": 4, "manager": 58943, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "8121-58943-10" ] }, { "id": 4235, "title": { "de": "CB2 Cannabinoid-Rezeptoren als neues therapeutisches Target für Eosinophilie-assoziierte Erkrankungen", "en": "Cannabinoid Receptor CB2 as a novel Target for Eosinophilic Diseases" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-01-01T01:00:00+01:00", "begin_effective": "2016-01-01T01:00:00+01:00", "end_planned": "2016-12-31T01:00:00+01:00", "end_effective": "2018-02-28T01:00:00+01:00", "assignment": "2016-01-19T12:19:01+01:00", "program": null, "subprogram": "Diagnostikum Preidler/Szolar Stipendium ", "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 50791, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-08", "ethics_committee": null, "edudract_number": null, "persons": [ "4235-50791-10" ] }, { "id": 3252, "title": { "de": "Rolle von PGE2 und EP Rezeptoren in der pulmonalen Endothelfunktion", "en": "Regulatory role of PGE2 and EP receptors in pulmonary endothelial cell function" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-05-01T02:00:00+02:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2018-04-30T02:00:00+02:00", "assignment": "2013-04-25T10:48:46+02:00", "program": null, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P25531", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 5690, "title": { "de": "Entwicklung von einem neuen diagnostischen Test für Brustkrebspatientinnen", "en": "Developing a blood-based diagnostic test for breast cancer patients" }, "short": "BCBM", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2019-01-01T01:00:00+01:00", "begin_effective": "2019-07-01T02:00:00+02:00", "end_planned": "2021-12-31T01:00:00+01:00", "end_effective": "2023-05-31T02:00:00+02:00", "assignment": "2019-02-14T15:25:54+01:00", "program": 60, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 60706, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 416 ], "funder_projectcode": "871284", "ethics_committee": null, "edudract_number": null, "persons": [ "5690-50777-12", "5690-51163-12", "5690-60706-10", "5690-99558-12", "5690-100698-12", "5690-112858-12" ] }, { "id": 3803, "title": { "de": "CB1/CB2R-unabhängigen Signale durch Cannabinoids in Endothel ", "en": "CB1/CB2R-independent cannabinoid signaling in endothelium" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-10-01T02:00:00+02:00", "begin_effective": "2013-10-01T02:00:00+02:00", "end_planned": "2016-09-30T02:00:00+02:00", "end_effective": "2018-11-30T01:00:00+01:00", "assignment": "2014-11-06T16:11:55+01:00", "program": 72, "subprogram": null, "organization": 14013, "category": 10, "type": 10, "partner_function": 4, "manager": 60219, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "P 27238", "ethics_committee": null, "edudract_number": null, "persons": [ "3803-60219-10" ] }, { "id": 3596, "title": { "de": "Interleukin-6 signal transduction pathways in glial cells", "en": "Interleukin-6 signal transduction pathways in glial cells" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2014-04-01T02:00:00+02:00", "begin_effective": "2014-04-01T02:00:00+02:00", "end_planned": "2015-03-31T02:00:00+02:00", "end_effective": "2015-03-14T01:00:00+01:00", "assignment": "2014-03-07T10:54:06+01:00", "program": 69, "subprogram": null, "organization": 14022, "category": 10, "type": 10, "partner_function": 4, "manager": 69755, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 9 ], "funder_projectcode": "J 3081 ", "ethics_committee": null, "edudract_number": null, "persons": [ "3596-69755-10" ] }, { "id": 4808, "title": { "de": "PR0STATAKREBS: neue Hoffnung dank alter Wirkstoffe.", "en": "Prostate cancer: New hope thanks to old drugs." }, "short": "Prostatakrebs", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2016-12-15T01:00:00+01:00", "begin_effective": "2016-02-01T01:00:00+01:00", "end_planned": "2017-04-01T02:00:00+02:00", "end_effective": "2017-03-31T02:00:00+02:00", "assignment": "2017-02-07T11:17:55+01:00", "program": null, "subprogram": null, "organization": 14014, "category": 10, "type": 10, "partner_function": 4, "manager": null, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 1743 ], "funder_projectcode": "MEFO-15", "ethics_committee": null, "edudract_number": null, "persons": [] }, { "id": 3230, "title": { "de": "Eye-Tracking mit 500Hz vs. 1250Hz: Höhere Abtastrate, neue Erkenntnisse...", "en": "Eye tracking with 500Hz vs. 1250Hz: Higher sampling rate, new findings¿" }, "short": null, "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-01-01T01:00:00+01:00", "begin_effective": "2013-04-01T02:00:00+02:00", "end_planned": "2013-12-31T01:00:00+01:00", "end_effective": "2014-03-30T01:00:00+01:00", "assignment": "2013-04-11T10:33:06+02:00", "program": null, "subprogram": null, "organization": 14010, "category": 10, "type": 10, "partner_function": 4, "manager": 77049, "contact": null, "status": 2, "research": 1, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 135 ], "funder_projectcode": null, "ethics_committee": null, "edudract_number": null, "persons": [ "3230-77049-10" ] }, { "id": 3562, "title": { "de": "Semantische Datenumgebung für die Gesundheitsversorgung", "en": "Semantic Data Platform for Healthcare" }, "short": "SEMCARE", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2013-10-01T02:00:00+02:00", "begin_effective": "2014-01-01T01:00:00+01:00", "end_planned": "2015-09-30T02:00:00+02:00", "end_effective": "2015-12-31T01:00:00+01:00", "assignment": "2014-02-10T12:08:55+01:00", "program": 24, "subprogram": "FP7-ICT-2013-SME-DCA", "organization": 14026, "category": 10, "type": 10, "partner_function": 2, "manager": 72306, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "611388", "ethics_committee": null, "edudract_number": null, "persons": [ "3562-60827-12", "3562-72306-10" ] }, { "id": 3833, "title": { "de": "Beurteilung der Eignung von SNOMED CT für umfangreiche, EU-weite elektronische Gesundheitsdienste ", "en": "Assessing SNOMED CT for Large Scale eHealth Deployments in the EU" }, "short": "ASSESS-CT_Horizon", "url": null, "abstract": { "de": null, "en": null }, "begin_planned": "2015-01-01T01:00:00+01:00", "begin_effective": "2015-02-01T01:00:00+01:00", "end_planned": "2015-12-31T01:00:00+01:00", "end_effective": "2016-07-31T02:00:00+02:00", "assignment": "2014-12-10T13:15:33+01:00", "program": 109, "subprogram": "PHC-34 eHealth Interoperability - Topic (iii) SNOMED CT for eHealth deployments\r\n", "organization": 14026, "category": 10, "type": 10, "partner_function": 2, "manager": 72306, "contact": null, "status": 2, "research": 2, "grant": 10, "event": null, "study": null, "language": null, "funders": [ 10 ], "funder_projectcode": "643818", "ethics_committee": null, "edudract_number": null, "persons": [ "3833-72306-10" ] }, { "id": 4247, "title": { "de": "1.2 -Innovative Nutzung von Information für klinische Versorgung und Biomarkerforschung - CBmed", "en": "1.2 - Innovative Use of Information for Clinical Care and Biomarker Research - CBmed" }, "short": "IICCAB (CBmed 1.2)", "url": null, "abstract": { "de": "Im Projekt CBmed 1.2, genannt IICCAB (Innovative Nutzung von Information für klinische Versorgung und Biomarkerforschung) werden im ersten Schritt bis 2018 im großen Maßstab klinische Daten zur besseren Weiterverwendung aufgearbeitet, um dann in vier unterschiedliche Pilotanwendungen einzufließen. \r\n\r\nDaten für Biomarkerforschung kommen aus nicht nur aus Speziallabors, sondern auch aus unterschiedlichsten Quellen, in denen klinischen Routinedaten abgelegt sind. Die Fusionierung dieser Daten erfordert eine automatische begriffliche Normierung, um sie zu aggregieren und so für innovative Anwendungen verfügbar zu machen. Den Kern des Systems bildet eine Hochleistungs-Datenbank, die die SAP-HANA-Technologie nutzt. Da ein wichtiger Teil der klinischen Informationen ausschließlich als Text vorliegt, muss dieser mit Hilfe von sprachtechnologischen Verfahren analysiert und auf ein standardisiertes Vokabular abgebildet werden. Die so gewonnenen Daten ermöglichen gemeinsam mit den bereits strukturiert vorliegenden Daten wie Laborparameter, Diagnosencodes usw. semantisch genormte Patientenprofile, mit denen in der ersten Phase von IICCAB vier Pilotanwendungen unterstützt werden.\r\n\r\nDie aufbereiteten Daten bilden die Grundlage für vier verschiedene Anwendungsszenarien: Das Szenario \"Recruiting\" wird es erleichtern, mit Hilfe graphischer Recherchewerkzeuge Patientengruppen anhand vielfältiger Merkmale zu definieren. Dies ist eine entscheidende Voraussetzung für Forschungsvorhaben aller Art, beispielsweise in der Biomarkerforschung. \r\nDas Szenario \"Prediction\" wurde entwickelt, um anhand von semantisch angereicherten Patientenprofilen Vorhersagen zu künftigen Ereignissen, wie etwa Wiederaufnahmen, zu treffen. Die Anwendung \"Patient Quick View\" stellt eine automatische Zusammenfassung entscheidungsrelevanter Patientendaten zur Verfügung, abhängig von den Präferenzen der jeweiligen Nutzergruppe und Arbeitssituation. Damit wird eine Alternative geschaffen zum zeitaufwändigen Recherchieren in elektronischen Patientenakten. Die Anwendung \"Coding\" unterstützt Ärztinnen und Ärzte bei der Kodierung von Krankheitsfällen für administrative Zwecke, indem IICCAB die verfügbaren Daten analysiert und den Nutzern Vorschläge für passende Diagnosen- und Prozeduren-Codes unterbreitet. \r\n\r\nDie erste Phase des vom Bund (FFG) geförderten IICCAB – Projekts innerhalb des österreichischen Kompetenzzentrums für Biomarkerforschung (CBMed - http://www.cbmed.org/de/) läuft bis Ende 2018 und wird von Stefan Schulz, Universitätsprofessor für Medizininformatik an der Medizinischen Universität Graz, geleitet. Kooperationspartner sind die Steiermärkischen Krankenanstaltengesellschaft m.b.H. (KAGes), die Med Uni Graz mit der Biobank, sowie die Softwarefirma SAP.\r\n", "en": "In Project 1.2 CBmed, called IICCAB (Innovative Use of Information for Clinical Care and Biomarker Research) large-scale clinical data sets are processed for better re-use. \r\n\r\nData for biomarker research come not only from specialized laboratories but also from different sources, in which routine clinical data are stored. The merging of these data requires automatic semantic normalization in order to aggregate them and to make them available for innovative applications. \r\nThe core of the system developed by IICCAB is a high performance database, which uses SAP HANA technology. Since an important part of clinical information is found exclusively as narratives within free-text fields of clinical databases, human language technology methods are required to analyse this content and to map it to a standardized vocabulary. The data obtained allow, together with already available structured data like lab parameters, disease codes, etc. semantically standardized patient profiles. \r\n\r\nThe processed data is the basis for four different application scenarios: \r\n\r\n1. \"Recruiting\" will facilitate patient cohorts in terms of various characteristics, using advanced graphical interfaces for querying and visualization. This is a crucial prerequisite for all kinds of clinical research, especially regarding biomarkers and the use of biosamples.\r\n\r\n2. \"Prediction\" will focus on predictive analytics based on semantically enriched patient profiles, in order to help estimate the probability of future events, such as hospital re-admissions. \r\n\r\n3. \"Patient QuickView\" will provide an automatic summary of decision-relevant patient data, depending on the preferences of each user group and task. Thus, an alternative is provided for time-consuming browsing through numerous documents in electronic health records. \r\n\r\n4. \"Coding\" supports physicians in the coding of disease cases for administrative purposes. IICCAB analyses available clinical data and proposes appropriate disease and procedure codes.\r\n\r\nIn the first phase of IICCAB (2016 – 2018), funded by FFG, CBmed cooperates with the Styrian Hospital Association (KAGes), the Institute of Medical Informatics, Statistics and Documentation of the Medical University of Graz, the Biobank Graz, and the German software company SAP under the lead of Stefan Schulz, university professor of medical informatics at the Medical University of Graz. 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