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GET /v1/research/publication/?format=api&offset=40&ordering=-year
{ "count": 155671, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=60&ordering=-year", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=20&ordering=-year", "results": [ { "id": 216455, "title": "The Use of Continuous Glucose Monitoring to Diagnose Stage 2 Type 1 Diabetes.", "abstract": null, "authors": [ "Mader, JK", "Wong, JC", "Freckmann, G", "Garcia-Tirado, J", "Hirsch, IB", "Johnson, SB", "Kerr, D", "Kim, SH", "Lal, R", "Montaser, E", "O'Donnell, H", "Pleus, S", "Shah, VN", "Ayers, AT", "Ho, CN", "Biester, T", "Dovc, K", "Farrokhi, F", "Fleming, A", "Gillard, P", "Heinemann, L", "López-Díez, R", "Maahs, DM", "Mathieu, C", "Quandt, Z", "Rami-Merhar, B", "Wolf, W", "Klonoff, DC" ], "year": 2025, "source": "J Diabetes Sci Technol. 2025; 19(4):1109-1127", "category": 1, "document_type": 3, "sci": "ISI:001499498100001", "pubmed": "40444471", "doi": "10.1177/19322968251333441", "pmc": "PMC12125016", "organizations": [ "216455-14080" ], "persons": [ "216455-50877-1" ], "imported": "2025-06-02T02:00:00+02:00", "journal": "J Diabetes Sci Technol", "issn": "1932-2968", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": false, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 217626, "title": "Neural blueprint of psychological resilience: Mapping NEO-FFI personality profiles onto resting-state fMRI network dynamics within the Human Connectome Project.", "abstract": null, "authors": [ "Repnik, L. G." ], "year": 2025, "source": "Doctoral Day 2025 - Medical University of Graz; FEB 13, 2025; Graz. 2025. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "217626-29447" ], "persons": [ "217626-114431" ], "imported": "2025-09-02T16:15:26+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 217619, "title": "A prospective comparison of five methods for rapid antimicrobial susceptibility testing (RAST) for Gram-negative bacteraemia.", "abstract": null, "authors": [ "Christine Uitz, Kristin Aurenhammer, Robert Krause, Michael Kroissenbrunner, Klaus Vander, Karl Dichtl\r\n" ], "year": 2025, "source": "ESCMID Global 2025 - the 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases; May 11-15, 2025; Vienna. 2025. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "217619-14023", "217619-29164" ], "persons": [ "217619-113933", "217619-112729", "217619-51976" ], "imported": "2025-09-02T13:21:58+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 216215, "title": "An overview of systematic reviews on the efficacy and safety of osteopathic techniques", "abstract": null, "authors": [ "Zipp, CR", "Semlitsch, T", "Togel, G", "Krenn, C", "Loder, C", "Jeitler, K", "Siebenhofer, A" ], "year": 2025, "source": "J BODYW MOV THER. 2025; 42: 1186-1197. ", "category": 1, "document_type": 1, "sci": "ISI:001483048600001", "pubmed": "40325655", "doi": "10.1016/j.jbmt.2025.03.018", "pmc": null, "organizations": [ "216215-27964", "216215-14026" ], "persons": [ "216215-100141-6", "216215-51098-6", "216215-63287-6", "216215-99378-6", "216215-100095-2", "216215-62926-6" ], "imported": "2025-05-19T10:07:33+02:00", "journal": "J BODYW MOV THER", "issn": "1360-8592", "collection_publisher": null, "collection_title": "JOURNAL OF BODYWORK AND MOVEMENT THERAPIES; ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 211584, "title": "Antidepressive pharmakotherapeutische Strategien bei Begleitdepressionen - Verträglichkeiten und Interaktionen.", "abstract": null, "authors": [ "Rothenhäusler, HB" ], "year": 2025, "source": "Gemeinsames Fortbildungsprogramm im WS 2024/2025 der Klin Abt f Psychiatrie u Psychotherapeut Medizin, Graz; LKH Graz II Standort Süd; Abt f Psychiatrie u Psychotherapeut Med, Klinikum Klagenfurt am Wörthersee.; FEB 7, 2025; Graz. 2025. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "211584-29444" ], "persons": [ "211584-50097" ], "imported": "2024-10-15T15:13:58+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 216246, "title": "Developing cardiac digital twin populations powered by machine learning provides electrophysiological insights in conduction and repolarization.", "abstract": null, "authors": [ "Qian, S", "Ugurlu, D", "Fairweather, E", "Toso, LD", "Deng, Y", "Strocchi, M", "Cicci, L", "Jones, RE", "Zaidi, H", "Prasad, S", "Halliday, BP", "Hammersley, D", "Liu, X", "Plank, G", "Vigmond, E", "Razavi, R", "Young, A", "Lamata, P", "Bishop, M", "Niederer, S" ], "year": 2025, "source": "Nat Cardiovasc Res. 2025; 4(5): 624-636. ", "category": 1, "document_type": 1, "sci": "ISI:001489931000016", "pubmed": "40379795", "doi": "10.1038/s44161-025-00650-0", "pmc": "PMC12084159", "organizations": [ "216246-14011" ], "persons": [ "216246-50966-6" ], "imported": "2025-05-19T02:00:00+02:00", "journal": "Nat Cardiovasc Res", "issn": "2731-0590", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 215566, "title": "Normative values for the hypoparathyroidism patient questionnaire (HPQ28) in the German general population.", "abstract": null, "authors": [ "Trummer, C", "Blaschke, M", "Quint, D", "Schulz, M", "Herrmann-Lingen, C", "Büttner, M", "Siggelkow, H" ], "year": 2025, "source": "J Patient Rep Outcomes. 2025; 9(1):38", "category": 1, "document_type": 1, "sci": "ISI:001459114400001", "pubmed": "40178746", "doi": "10.1186/s41687-025-00868-3", "pmc": "PMC11968587", "organizations": [ "215566-14080" ], "persons": [ "215566-85701-1" ], "imported": "2025-04-09T02:00:00+02:00", "journal": "J Patient Rep Outcomes", "issn": "2509-8020", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 217366, "title": "Pathobiology and genetics of pulmonary hypertension", "abstract": null, "authors": [ "Olschewski, A", "Schermuly, RT", "Pullamsetti, S", "Nagaraj, C", "Dorfmüller, P", "Eichstaedt, CA", "Foris, V", "Graef, S" ], "year": 2025, "source": "Z PNEUMOLOGIE. 2025; ", "category": 1, "document_type": 3, "sci": "ISI:001542555200001", "pubmed": null, "doi": "10.1007/s10405-025-00628-6", "pmc": null, "organizations": [ "217366-14087", "217366-14044" ], "persons": [ "217366-58984-6", "217366-87980-6", "217366-54345-2" ], "imported": "2025-08-20T10:46:55+02:00", "journal": "Z PNEUMOLOGIE", "issn": "2731-7404", "collection_publisher": null, "collection_title": "ZEITSCHRIFT FUR PNEUMOLOGIE; ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": false, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 217373, "title": "Overview of Pediatric Metabolic Disorders Diagnosis and Treatment in Daily Routine", "abstract": null, "authors": [ "Baghdasaryan, A", "Zöggeler, T" ], "year": 2025, "source": "PADIATR PADOL. 2025; ", "category": 1, "document_type": 1, "sci": "ISI:001536961800001", "pubmed": null, "doi": "10.1007/s00608-025-01301-0", "pmc": null, "organizations": [ "217373-14091" ], "persons": [ "217373-58695-2" ], "imported": "2025-08-20T10:46:55+02:00", "journal": "PADIATR PADOL", "issn": "0030-9338", "collection_publisher": null, "collection_title": "PAEDIATRIE UND PAEDOLOGIE; ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": false, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 217372, "title": "Left Ventricular Hypertrophy: an unusual Case", "abstract": null, "authors": [ "Schwegel, N", "Ablasser, K" ], "year": 2025, "source": "J KARDIOL. 2025; 32(7-8): 176-178. ", "category": 1, "document_type": 4, "sci": "ISI:001541878700007", "pubmed": null, "doi": null, "pmc": null, "organizations": [ "217372-14083" ], "persons": [ "217372-116542-2", "217372-60377-2" ], "imported": "2025-08-20T10:46:55+02:00", "journal": "J KARDIOL", "issn": "1024-0098", "collection_publisher": null, "collection_title": "JOURNAL FUR KARDIOLOGIE; ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": false, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 217396, "title": "Genomic profiling of circulating tumor DNA using targeted capture sequencing in advanced HR+/HER- breast cancer patients", "abstract": "Background: HR-positive, HER2-negative breast cancer (HR+/HER2-) is the most common subtype of breast cancer, accounting for around 60-70%. PIK3CA mutations occur in up to 40% of patients and permanently activate the PI3K/AKT/mTOR signaling pathway. This can lead to resistance to therapy and worsen the prognosis. While these mutations are usually determined from tumor tissue, the analysis of cell-free tumor DNA (ctDNA) in plasma offers a minimally invasive alternative, especially for metastases that are difficult to biopsy. The aim of this study was to compare the detection of PIK3CA mutations using SiMSen-Seq, and the AVENIO ctDNA Expanded Kit and to test whether AVENIO can detect additional clinically relevant alterations.
\r\nMethods: 47 patients with HR+/HER2- metastatic breast cancer (mBC) were examined. Blood samples were taken before starting palliative therapy (32 before first-line and 15 before second-line therapy). Tumor fraction was estimated using mFAST-SeqS (z-score). Two methods were used for mutation analysis. On the one hand, SiMSen-Seq, a PCR-based NGS method for the highly sensitive detection of eleven PIK3CA hotspot mutations. On the other hand, AVENIO ctDNA Expanded Kit, an NGS panel for 77 cancer-relevant genes. Sequencing was performed on Illumina platforms and resulting data were analyzed bioinformatically.
\r\nResults: PIK3CA mutations were detected in 21 of 47 patients (44.7%). The most frequent variants were H1047R, E542K and C420R. 35 of 40 mutations (87.5%) were detected by both methods. Only few mutations (n = 4, corresponding to 8.5%) were detected exclusively by one method and these were mostly at low VAF (variant allele frequency) (<1%). AVENIO additionally identified mutations in TP53, ESR1, SMAD4, GATA3 and AKT1. Higher tumor proportions (z-scores) correlated with visceral metastasis.
\r\nConclusion: The AVENIO ctDNA Expanded Kit showed comparable sensitivity to SiMSen-Seq in PIK3CA detection but additionally enabled a broader molecular analysis. The combination of AVENIO, SiMSen-Seq and mFAST-SeqS provides a powerful tool for non-invasive characterization and monitoring of HR+/HER2- mBC. This would allow therapies to be adapted more specifically and resistance developments to be detected at an early stage. Especially in situations where tissue samples are difficult to obtain.", "authors": [ "Potocnik, N" ], "year": 2025, "source": " [ Diplomarbeit/Master Thesis (UNI) ] TU Graz; 2025. pp.66. ", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2025-08-22T14:29:23+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "TU Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": true, "local_affiliation": false }, { "id": 217469, "title": "The genomic landscape of matching primary and metastatic melanoma tumours uncovers relevant pathway for the metastatic process.", "abstract": null, "authors": [ "Smit, D", "Kao, Y-C", "Oey, H", "Harris, T", "Tom, L", "Jagirdar, K", "Richtig, G", "Aigelsreiter, A", "Richtig, E", "Soyer, HP", "Stark M." ], "year": 2025, "source": "EJC: Volume 3, Supplement 1, 100504; 2025. 2025; Volume 3: 100504-100504.-11th World Congress of Melanoma and 21st EADO Congress.; April, 3-5, 2025; Athens, Greece. 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