Publication List

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            "title": "Update der systemischen Therapie bei fortgeschrittenen retroperitonealen Sarkomen",
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            "title": "Assessment of the estrogenic activity of phytoestrogens isolated from bourbon and beer.",
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                "Segues, N",
                "de, la, Pinta, FJD",
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                "Peñate, Y",
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                "Cereceda, L",
                "Minguez, P",
                "de, la, Fuente, L",
                "Requena, L",
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            "id": 107003,
            "title": "Radiation induced cutaneous ulcer on the back in a patient with congenital anomaly of the upper cava system.",
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                "Prenner, G",
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            "source": "Interact Cardiovasc Thorac Surg. 2011; 12(2):290-2",
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        {
            "id": 214691,
            "title": "Diagnose und Therapiemöglichkeiten von angeborenen Herzfehlern in der Pädiatrie",
            "abstract": "Die Prävalenz für angeborene Herzfehler (AHF) liegt bei 1,0% aller Lebendgeborenen. Somit zählen sie zu den häufigsten Organfehlbildungen bei Neugeborenen. Innerhalb des letzten Jahrhunderts konnte durch starke Verbesserungen in der kardiovaskulären Diagnostik und Therapien eine erhöhte Überlebensrate von angeborenen Herzfehlern erzielt werden. Therapeutische Eingriffe werden zunehmend mittels interventioneller Methoden durchgeführt. Beim Ventrikelseptumdefekt (VSD) zählt dies beispielsweise zum Routineverfahren. Die Diagnose von angeborenen Herzfehlern erfolgt mittels Elektrokardiogramms (EKG), Thorax-Röntgen und Echokardiographie. Herzfehler können bereits pränatal sichtbar sein. Der Neuigkeitswert dieser Arbeit besteht darin, vorhandene Literatur und Guidelines mit neuen Studien zu vergleichen und einen kompakten Überblick über den momentanen Kenntnisstand verschiedener AHF bei pädiatrischen Patient*innen zu geben. Sie soll im klinischen Alltag als Nachschlagewerk unterstützen. Die Forschungsfrage ist für Frauen und Männer gleichermaßen bedeutsam, da sowohl Mädchen als auch Buben davon betroffen sein können.",
            "authors": [
                "Resch, J"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 79",
            "category": 5,
            "document_type": 15,
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            "country": "40",
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        {
            "id": 214133,
            "title": "The Magic Power of Exercise - Let’s Get Mobilized: Einfluss eines aktiven Lebensstils auf den hepatischen Fettgehalt. Ein Pilotprojekt",
            "abstract": "Hintergrund: Inaktivität ist eines der größten gesundheitlichen Probleme in der heutigen Gesellschaft. Das führt unter anderem dazu, dass kardiovaskuläre Ereignisse die Haupttodesursache weltweit sind. Inaktivität führt aber auch zu metabolischen Komplikationen, wie der metabolischen Dysfunktion assoziierten steatotischen Lebererkrankung (MASLD, metabolic dysfunction associated steatotic liver disease). Möglichkeiten, das Ausmaß körperlicher Aktivität zu erhöhen, sind die aktive Gestaltung des Arbeitsweges sowie die Umsetzung eines individuellen Herzfrequenz gesteuerten Trainingsplans. Der gesundheitliche Nutzen dieser zwei Maßnahmen wurde in dieser Pilotstudie untersucht und miteinander verglichen.",
            "authors": [
                "Hillisch, K"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 53",
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            "document_type": 15,
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        {
            "id": 214693,
            "title": "EHealth literacy in emergency care: a scoping review",
            "abstract": "Background: The emergency department (ED) plays a critical role in the healthcare system. However, the increase in non-urgent visits can contribute to overcrowding negatively impacting patient outcomes, healthcare professionals and institutional costs. According to state-of-the-art literature, health literacy is correlated with preventable, non-urgent ED visits. With the growing use of technology and online health information, eHealth literacy has become increasingly important. The aim of this thesis is to provide an overview of eHealth literacy in emergency care.",
            "authors": [
                "Paller, J"
            ],
            "year": 2025,
            "source": "Masterstudium; Pflegewissenschaft; [ Masterarbeit ] Medizinische Universität Graz; 2025. pp. 68",
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            "university": "Medizinische Universität Graz",
            "country": "40",
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        {
            "id": 215258,
            "title": "Hypermenorrhoe bei weiblichen Jugendlichen mit Von Willebrand-Syndrom. Zusammenfassung derzeitiger Kenntnis \r\nüber Klinik, Diagnostik und Therapie in der pädiatrischen Gynäkologie",
            "abstract": "Zusammenfassung: Das Von Willebrand-Syndrom ist die häufigste angeborene Hämostasestörung (etwa 1% der Bevölkerung) und kann sich bei weiblichen Jugendlichen  durch zu starke Regelblutungen manifestieren. Seit Einführung der PALM-COEIN Klassifikation 2011 durch FIGO, welche 9 unterschiedliche Ursachen für abnorme uterine Blutungen definiert, sollten Koagulopathien als Grund für Hypermenorrhoe – oder besser gesagt Heavy Menstrual Bleeding/HMB – in der Diagnostik berücksichtigt werden. Eine Zusammenschau themenrelevanter wissenschaftlicher Publikationen bietet einerseits einen Überblick zu Hypermenorrhoe als Symptom des Von Willebrand-Syndroms im Jugendalter, andererseits werden dessen gynäkologische Folgen für weibliche Jugendliche thematisiert. Zusätzlich zeigt diese Arbeit Optionen zu Diagnostik und Therapie auf. Sie soll einen Beitrag zur Sensibilisierung jugendgynäkologischer Praxis leisten bezogen auf schnelles Erkennen und Behandeln des Von Willebrand-Syndroms aufgrund von Hypermenorrhoe. Nur so können etwaige spätere Folgen verhindert bzw. therapeutische Vorkehrungen getroffen werden.",
            "authors": [
                "Kohlmaier-Kohlhauser, A"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. ",
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        {
            "id": 214690,
            "title": "Urine-Metabolomics as Non-Invasive Markers for Adiposity in Children",
            "abstract": "BACKGROUND: This thesis is part of a bigger project (the “Health and Academic Performance with Happy Children (HAPHC)”-project), a 3-year controlled intervention study, that observed the impact of daily integrated physical activity on health and academic performance of primary school children, aiming at counteracting obesity (OB). Applying ultrasound (US) in a standardized protocol has been found a reliable tool for measuring the thickness of subcutaneous adipose tissue (SAT). New knowledge in the field of metabolomics has shown the potential of identifying biomarkers for certain diseases, including OB, by analysing biofluids.",
            "authors": [
                "Lagger, M"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 87",
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        {
            "id": 215259,
            "title": "Immune Response to ZX00 Implants in Healthy and Osteoporotic Rats",
            "abstract": "Background: In the EU, one out of three women and one out of five men will experience an osteoporotic fracture over their course of life. In 2019, 4.28 million osteoporotic-associated fragility fractures were reported. Due to increased life expectancy, the number of fragility fractures is estimated to reach 5.28 million by 2034. Osteosynthesis of osteoporotic bone presents a particular challenge due to alterations in the mechanical, immunological, and regenerative properties of the bone. Therefore, the requirements of implant materials changed to gain a better osseointegration, osteoconductivity, and osteoinductivity. Biodegradable magnesium (Mg)-based implants, such as ZX00, showed promising results in animal studies and in a first in-men study. Recently, results in osteoporotic rats revealed accelerated degradation of ZX00 compared to healthy rats. Hence, we aimed to investigate the systemic osteoimmunomodulatory changes during osteoporosis development and osteogenic properties of ZX00 in a rat model. Therefore, we assessed in the first phase of the study the systemic immunomodulatory response and the bone morphologic changes to the onset of osteoporosis and in the second phase the local morphogenic and systemic immune response to ZX00 in osteoporotic and healthy conditions.",
            "authors": [
                "Freudenthal-Siefkes, J"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 63",
            "category": 5,
            "document_type": 15,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [],
            "persons": [],
            "imported": "2025-03-17T11:32:25+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
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            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 213353,
            "title": "Clinical relevance of immunological biomarkers in NSCLC",
            "abstract": "Recommendation of immune checkpoint inhibitors (ICIs) for the treatment of non-small cell lung cancer (NSCLC) depends on PD-L1 expression on tumor cells. Although PD-L1 expression levels correlate with response to ICI treatment, PD-L1 alone often fails to predict treatment response. \r\nIn our retrospective cohort of early-stage NSCLC patients, we compared PD-L1 expression in patients with available initial biopsy samples, samples from primary curative surgical and rebiopsy samples in case of subsequent recurrence. In all cases Ventana PD-L1 (SP263) assay was used. We scored PD-L1 expression into clinically relevant groups defined as 0%, 1-49% and ≥50%. Our main interest was the change of PD-L1 score-group between the different matched tumor samples in NSCLC patients.\r\nIn total 395 patients with stage I-III NSCLC were identified forming our main cohort. 136 (34%) out of 395 patients relapsed. For 87 patients of these patients at least two specimens for PD-L1 expression comparison, namely initial biopsy and rebiopsy were available. In 72 cases PD-L1 expression could be compared between all-time points. Between initial preoperative biopsy and matched surgical specimens, a clinically relevant conversion of PD-L1 expression group was found in 25 patients (34.7%). We could not identify a statistically significant influence of neoadjuvant treatment on PD-L1 alteration (p=0.39). When we compared PD-L1 expression from preoperative samples with rebiopsy samples a clinically relevant change in PD-L1 expression was found in 32 (36.8%) out of 87 patients. Similar to the neoadjuvant therapy, adjuvant treatment was also not associated with a change in the PD-L1 expression group (p=0.16). Overall, 39 patients (54.2%) showed at least one change into a different PD-L1 score group. In fourteen patients (19.4%) PD-L1 expression score group changed twice and in five patients (6.9%) PD-L1 score group was different in every analysed sample.\r\nWe conclude, that there is clinically relevant PD-L1 expression change in NSCLC patients during the course of disease. We hypothesize that there is an unmet need for guidelines to define PD-L1 testing strategy including indication for re-assessment, biopsy number and appraisal of surgical specimens.",
            "authors": [
                "John, N"
            ],
            "year": 2025,
            "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2025. pp. 103",
            "category": 5,
            "document_type": 16,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [],
            "persons": [],
            "imported": "2025-01-23T09:25:31+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
            "impactfactor_norm": null,
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            "conference_name": null,
            "conference_place": null,
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            "invited_lecture": false,
            "keynote_speaker": false,
            "selected_presentation": false,
            "biobank_use": false,
            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 214128,
            "title": "Modern Anti-Diabetics in Cardiovascular Disease",
            "abstract": "The clinical study \"Empagliflozin in Acute Myocardial Infarction\" (EMMY) was the first to demonstrate positive effects of empagliflozin on cardiac parameters. However, data regarding its effects on inflammation, echocardiographic parameters, and arrhythmias are lacking. The aim of this work is to analyse the effects of sodium-glucose cotransporter-2 inhibitors (SGLT2-I) on inflammatory markers, echocardiographic parameters, and arrhythmic burden, and to investigate whether initial electrocardiogram (ECG) values are predictive of changes in cardiac markers following acute myocardial infarction (AMI).",
            "authors": [
                "Benedikt, M"
            ],
            "year": 2025,
            "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2025. pp. 132",
            "category": 5,
            "document_type": 16,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [],
            "persons": [],
            "imported": "2025-02-10T11:27:26+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
            "impactfactor_norm": null,
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            "impactfactor_norm_category": null,
            "impactfactor_norm_super": null,
            "impactfactor_norm_super_year": null,
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            "citations": null,
            "conference_name": null,
            "conference_place": null,
            "conference_international": false,
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            "keynote_speaker": false,
            "selected_presentation": false,
            "biobank_use": false,
            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 214687,
            "title": "Prognostische Relevanz und Komplikationsrate von Biopsien der Lippenspeicheldrüsen beim Sjögren Syndrom",
            "abstract": "Einleitung: Das Sjögren Syndrom ist eine systemische Autoimmunerkrankung, bei der es in erster Linie zur Manifestation an den exokrinen Drüsen kommt. Xerophthalmie und Xerostomie stellen die Hauptsymptome dar, jedoch sind auch extraglanduläre Manifestationen wie Fatigue, Arthralgien oder neurologische Manifestationen nicht ungewöhnlich. Die Diagnose des Sjögren Syndroms erfordert gemäß den aktuellen ACR/EULAR Leitlinien von 2016 entweder den Nachweis von Ro-Antikörpern, oder eine Lippenspeicheldrüsenbiopsie mit einem Fokus-Score ≥ 1. Der Fokus-Score stellt dabei einen Surrogatorparameter für das Ausmaß der lymphozytären Entzündung in den Speicheldrüsen dar. Ein Fokus ist definiert als Ansammlung von ≥ 50 Lymphozyten, der Fokus-Score gibt die Anzahl der Foci pro 4 mm² Drüsengewebe an. Während Focus-Score Werte ≥ 1 die Diagnose des Sjögren Syndroms (bei vorliegender Klinik) bestätigen, ist weniger über die Bedeutung von Fokus-Score-Werten zwischen 0 und 1 bekannt, also Fälle, bei denen zwar eine für das Sjögren Syndrom typische Infiltration vorliegt, aber nicht in ausreichendem Ausmaß. Die vorliegende Arbeit befasst sich daher mit der Bedeutung subdiagnostischer Fokus-Score-Werte für Verlauf und Prognose von Patient*innen. Außerdem wird untersucht, wie hoch die Komplikationsrate bei Lippenspeicheldrüsenbiopsien ist.",
            "authors": [
                "Ehart, G"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 96",
            "category": 5,
            "document_type": 15,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [],
            "persons": [],
            "imported": "2025-02-25T09:18:28+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
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            "conference_name": null,
            "conference_place": null,
            "conference_international": false,
            "scientific_event": false,
            "invited_lecture": false,
            "keynote_speaker": false,
            "selected_presentation": false,
            "biobank_use": false,
            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 212911,
            "title": "The Use of Magnesium-based Bioresorbable Screws in the Surgical Treatment of Fractures",
            "abstract": "Background: In a pilot study, the magnesium-based screw ZX00 demonstrated successful healing of medial malleolar fractures while gradually resorbing. The proof of concept and excellent 1-year outcomes generated interest beyond the first year. This study reports the clinical outcomes after 2½ years and investigates the changes in bone microarchitecture following the resorption of ZX00, as well as after the removal of conventional implants around the ankle joint.\r\nMethods: All imaging data from the pilot study involving ZX00 screws for medial malleolar fractures were analyzed. The initial study included 20 adults who received either one or two ZX00 screws (most commonly two) for medial malleolar fracture fixation. Each 3.5 mm ZX00 screw had a volume of 243.3 mm³. In cases of combined injuries, conventional fibulo-tibial positioning screws were used for syndesmotic instability (n=9), and conventional plates/screws were applied for additional fractures (n=14). Fibulo-tibial positioning screws were removed after 6–8 weeks, while plates/screws were removed based on patient preference or discomfort (n=8). Two cases were lost to follow-up or excluded. Clinical follow-up and radiographs for the remaining 18 patients extended to an average of 2½ years post-ZX00 implantation. Of these, 15 patients underwent CT scans at an average of 3½ years post-implantation, including six cases with high-resolution CTs (HR-CTs) conducted between 2 and 3 years. CT scans were analyzed for changes in bone microarchitecture following ZX00 resorption. HR-CTs specifically evaluated ZX00 traces and enabled volumetric measurements of trabecular voids at the former ZX00 implantation sites. Lastly, the cohort comprised eleven patients with CT scans after hardware removal, allowing the evaluation of implantation sites of conventional implants (n=12).\r\nResults: At around 2½ years, there were no clinical complications, and patients remained pain-free. The radiographs revealed no visibility of ZX00 screws in 94% (17 of 18) of cases. Additionally, bone texture at the ZX00 implantation site was rated as homogeneous in 83% (15 of 18) of cases and slightly inhomogeneous in 17% (3 of 18). CT scans demonstrated sclerotic voids in the trabecular bone following ZX00 resorption in 100% (15 cases) after approximately 3½ years. Among the six HR-CTs conducted between 2 and 3 years, one case showed complete ZX00 screw resorption, while five cases exhibited tiny, irregularly shaped ZX00 traces. The trabecular void volumes measured in HR-CT were 596.2 ± 275.7 mm³. The CTs after conventional hardware removal showed sclerotic screw holes in the trabecular bone, both following the removal of fibulo-tibial positioning screws (6-8 weeks implant residence) and plates/screws (approximately 1½ years).\r\nDiscussion: The clinical outcomes confirm the success of the intervention with ZX00 screws, demonstrating true bioresorbability with near-complete resorption 2 to 3 years post-implantation. Radiographs show an increasingly homogeneous bone texture at the ZX00 implantation sites over time, reflecting remodeling and strengthening of adjacent trabecular bone, a phenomenon also observed after conventional screw removal. However, CT and HR-CT scans reveal the full extent of structural changes following ZX00 screw resorption, including voids that differ in size from those associated with conventional screws. This underscores the need for advanced imaging techniques when assessing bioresorbable implants.\r\n",
            "authors": [
                "Labmayr, V"
            ],
            "year": 2024,
            "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2024. pp. 141",
            "category": 5,
            "document_type": 16,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [
                "212911-14052"
            ],
            "persons": [
                "212911-104358"
            ],
            "imported": "2025-01-08T09:25:45+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
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            "conference_name": null,
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            "conference_international": false,
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            "keynote_speaker": false,
            "selected_presentation": false,
            "biobank_use": false,
            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 215265,
            "title": "Improving adherence to immunosuppression after liver or kidney transplantation in individuals with impairments in personality functioning – A randomized controlled single center feasibility study.",
            "abstract": null,
            "authors": [
                "Wagner-Skacel, J"
            ],
            "year": 2024,
            "source": "Austrotransplant 2024 ; OKT 16-18, 2024; Salzburg. 2024. ",
            "category": 3,
            "document_type": null,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [
                "215265-29447"
            ],
            "persons": [
                "215265-59288"
            ],
            "imported": "2025-03-17T11:35:25+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": null,
            "country": null,
            "case_report": false,
            "impactfactor": null,
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            "impactfactor_norm_super_year": null,
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            "citations": null,
            "conference_name": true,
            "conference_place": true,
            "conference_international": false,
            "scientific_event": true,
            "invited_lecture": false,
            "keynote_speaker": false,
            "selected_presentation": true,
            "biobank_use": false,
            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": true
        },
        {
            "id": 215248,
            "title": "Transfusionslast und Eisenüberladung bei Kindern, Jugendlichen und jungen Erwachsenen mit onkologischen Erkrankungen - retrospektive Studie",
            "abstract": "Transfusionsbedingte Eisenüberladung bei pädiatrisch-onkologischen Patient*innen kann langfristige hepatische, kardiale und endokrine Komplikationen verursachen. Obwohl die Prävalenz von Eisenüberladung (IO) in dieser Patientengruppe in einigen Studien untersucht wurde, fehlen einheitliche Richtlinien für das Management. Aufgrund der Heterogenität der Patientengruppe ist es wichtig, potenzielle Risikofaktoren für Eisenüberladung zu identifizieren. Dazu wurde in dieser retrospektiven Studie die Transfusionsbelastung von 219 Patient*innen im Alter von 0 bis 29 Jahren, bei denen eine maligne Erkrankung diagnostiziert wurde und die ihre zytotoxische Therapie (Chemotherapie und/oder Bestrahlung) von Jänner 2016 bis Juni 2022 in der Abteilung für Pädiatrische Hämato-/Onkologie des Universitätsklinikums Graz abgeschlossen haben, analysiert. Demographische und krankheitsbezogene Variablen wie Alter, Geschlecht, Wachstum, Diagnose, Therapiedauer, Therapieintensität und Komplikationen wurden im Zusammenhang mit den Transfusionsparametern analysiert. Das durchschnittliche Alter bei der Diagnosestellung lag bei 103 Monaten (0-350) und die mediane Behandlungsdauer betrug 340 Tage (23-1502). Insgesamt erhielten 135 Patient*innen (87,7 %) Transfusionen von Erythrozytenkonzentraten. Der IO wurde anhand etablierter Grenzwerte aus der Literatur bestimmt (≥10 Erythrozytenkonzentrate, ≥100 ml/kg Körpergewicht, ≥1000 ml/m2 Körperoberfläche und geschätzte hepatische Eisenbelastung ≥1,6 mgFe/g Trockengewicht der Leber). Die Kohorte erhielt im Median 11 Erythrozytenkonzentrate (1–99). Das kumulative Transfusionsvolumen betrug im Median 2824 ml (133–24.122), das Volumen bezogen auf das Körpergewicht 110,9 ml/kg (4,4–493,3) und auf die Körperoberfläche 2993,5 ml/m2 (165,8–12.586,2). Die durchschnittliche hepatische Eisenbelastung betrug 2,0 mg Fe/g (0,1–17,1). Mehr als 10 Erythrozytenkonzentrate erhielten 62,2 % der Patient*innen, 55,6 % erhielten mehr als 100 ml/kg Körpergewicht, 83,0 % mehr als 1000 ml/m2 Körperoberfläche und 58,5 % wiesen eine geschätzte hepatische Eisenüberladung von ≥1,6 mg Fe/g auf. Als Risikopatient*innen für Eisenüberladung wurden Kinder unter 12 Jahren sowie Patient*innen, die an akuten Leukämien, Knochentumoren, embryonalen Tumoren und hochmalignen Gliomen erkrankt sind, identifiziert. Außerdem ging eine höhere Transfusionsbelastung mit längerer Therapiedauer, intensiveren Therapieintensitätsleveln sowie gehäuftem Auftreten von potenziell IO-bedingten Komplikationen einher. Diese Risikogruppen sollten in Zukunft auf Eisenüberladung gescreent und anschließend monitorisiert sowie bei Bedarf therapiert werden. Dazu zählen die Bestimmung von Serumferritin und die Messung der hepatischen und kardialen Eisenkonzentration mittels MRT-T2*.",
            "authors": [
                "Bauer, S"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 105",
            "category": 5,
            "document_type": 15,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [],
            "persons": [],
            "imported": "2025-03-17T11:32:25+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
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            "conference_international": false,
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            "keynote_speaker": false,
            "selected_presentation": false,
            "biobank_use": false,
            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 215247,
            "title": "Outcome of plexus-reconstructions at the age of over 40 years: a follow-up study",
            "abstract": "Injuries of the brachial plexus can be the result of severe trauma like traffic or forestry accidents or birth trauma. The choice of therapy, the prognosis, and the outcome of plexus injuries – particularly regarding the functionality and usability of the affected extremity in everyday life – depend on several factors. These include the exact location of the nerve lesion in the brachial plexus (spinal root, trunci, divisions, cords or terminal branches), the affected arm function (shoulder function, elbow flexion, motor and sensory deficits in the forearm and hand), the form of injury (stretch, rupture, avulsion – neurapraxia, axonotmesis or neurotmesis), the mechanism of injury (compression, stretch or laceration of the nerve) and the mode of reconstruction (neurolysis, direct nerve repair or intra-/extraplexial nerve transfers). Brachial plexus reconstruction yields a good functional outcome in children and young adults, however, data and literature on the outcome after surgical reconstruction of brachial plexus injuries in patients over 40 years are scarce. Therefore, this thesis addresses the question whether brachial plexus reconstructions are effective in patients over 40 and aims to show the outcomes in this patient group.",
            "authors": [
                "Kerbl, S"
            ],
            "year": 2025,
            "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. ",
            "category": 5,
            "document_type": 15,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [],
            "persons": [],
            "imported": "2025-03-17T11:32:25+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": "Medizinische Universität Graz",
            "country": "40",
            "case_report": false,
            "impactfactor": null,
            "impactfactor_year": null,
            "impactfactor_norm": null,
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            "bmf_use": false,
            "zmf_use": false,
            "local_affiliation": false
        },
        {
            "id": 215242,
            "title": "Alkoholische Hepatitis bei ALD-Zirrhose - Transplantationspsychologie.",
            "abstract": null,
            "authors": [
                "Univ.-Prof.in Priv.-Doz. Dr. Jolana Wagner-Skacel"
            ],
            "year": 2024,
            "source": "57. ÖGGH Jahrestagung & 34. Fortbildungskurs & 2. Pre-Symposium Young ÖGGH; 12.06. - 15.06.2024; Salzburg Congress, Auerspergstraße 6, 5020 Salzburg. 2024. ",
            "category": 3,
            "document_type": null,
            "sci": null,
            "pubmed": null,
            "doi": null,
            "pmc": null,
            "organizations": [
                "215242-29447"
            ],
            "persons": [
                "215242-59288"
            ],
            "imported": "2025-03-17T11:16:23+01:00",
            "journal": null,
            "issn": null,
            "collection_publisher": null,
            "collection_title": null,
            "edition": null,
            "university": null,
            "country": null,
            "case_report": false,
            "impactfactor": null,
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            "conference_name": true,
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            "zmf_use": false,
            "local_affiliation": true
        }
    ]
}