Publication List
List publications.
Fields
id (integer)
Primary key.
name (string)
Name of doctoral school.
emails (string[])
Contact emails.
Expansions
To activate relation expansion add the desired fields as a comma separated
list to the expand query parameter like this:
?expand=<field>,<field>,<field>,...
The following relational fields can be expanded:
personscategorydocumentorganization_authorship
Filters
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Possible exact filters:
yearcategorydocumentpersons
For advanced filtering use lookups:
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All fields with advanced lookups can also be used for exact value matches as described above.
Possible advanced lookups:
year:gt,gte,lt,ltesci:iexact,contains,icontains,startswith,istartswithpubmed:iexact,contains,icontains,startswith,istartswithdoi:iexact,contains,icontains,startswith,istartswithpmc:iexact,contains,icontains,startswith,istartswithorganization_authorship:inimpact:isnull,gt,gte,lt,lteimported:isnull,gt,gte,lt,lte,date
GET /v1/research/publication/?format=api&offset=151980&ordering=year
{ "count": 156885, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=152000&ordering=year", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=151960&ordering=year", "results": [ { "id": 212370, "title": "Hymenoptera venom-induced anaphylaxis patients with a clonal mast cell disease undergoing venom immunotherapy respond with senescent CD8+ TEM cells", "abstract": null, "authors": [ "Teufelberger, AR", "Cerpes, U", "Dan, AR", "Bokanovic, D", "Fink-Puches, R", "Mahnke, NA", "Vera Ayala, CE", "Chu Wang, SY", "Pyatilova, P", "Fedai, K", "Siebenhaar, F", "Kränke, B", "Wolf, P" ], "year": 2024, "source": "Skin Deep (Supplement). 2024; November(4):47-48.-ÖGDV Jahrestagung 2024; NOV 28-30, 2024; Graz, AUSTRIA. ", "category": 2, "document_type": 19, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212370-14047" ], "persons": [ "212370-107955", "212370-51618", "212370-51954", "212370-52589" ], "imported": "2024-12-02T11:51:31+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": true, "local_affiliation": true }, { "id": 212373, "title": "Familiär vererbbare Erkrankungen in der Allgemeinmediziner*in Ordination", "abstract": "Die Genetik, die Lehre der Vererberung, ist eine relativ junge Wissenschaft und beschäftigt sich mit der Ausbildung von erblichen Merkmalen sowie der Weitergabe von Genen an die nächste Generation. Es wurde im Rahmen dieser Diplomarbeit versucht, die Rolle des Hausarztes und der Hausärztin anhand der familiär vererbten Erbkrankheiten Autismus/Schizophrenie, Kolorektales Karzinom und zystische Fibrose, näher zu bringen.Dazu werden zuerst diese Krankheitsbilder näher beleuchtet und definiert.Der Schwerpunkt liegt auf den genetischen Faktoren und den Behandlungsmethoden. Im letzten Teil der Arbeit wird auf die Rolle des gut ausgebildeten Allgemeinmediziners und Allgemeinmedizinerin eingegangen.", "authors": [ "Dordevic, P" ], "year": 2024, "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2024. pp. 52", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2024-12-02T13:26:59+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Medizinische Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 212407, "title": "Sex-based differences in a mouse model of experimental colitis housed in environmental enrichment", "abstract": null, "authors": [ "Petracco, G", "Tatzl, E", "Faimann, I", "Kienzl, M", "Gruden, E", "Schicho, R", "Reichmann, F" ], "year": 2024, "source": "Posterbook of the 2nd INGE St. Day. 2024; -Second public INGE St. Day; DEC 3, 2024; Graz, AUSTRIA. ", "category": 2, "document_type": 19, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212407-14022" ], "persons": [ "212407-116402", "212407-118787", "212407-71386", "212407-50186", "212407-56687", "212407-97983", "212407-99558" ], "imported": "2024-12-03T15:16:49+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": true, "zmf_use": false, "local_affiliation": true }, { "id": 212412, "title": "Update zielgerichtete Therapien beim NSCLC – Fokus KRAS Mutation und seltene Treiber. Diskutant.", "abstract": null, "authors": [ "Brcic, L" ], "year": 2024, "source": "OeGHO OnCoLine Webinar ; DEZ 03, 2024; Vienna, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212412-14020" ], "persons": [], "imported": "2024-12-03T19:35:02+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 212415, "title": "Clinical Neuropsychology: Neuronal Plasticity and Repair", "abstract": null, "authors": [ "Pinter, D", "Hechenberger, S", "Helmlinger, B", "Jordan, S", "Enzinger, C" ], "year": 2024, "source": "Initiative Gehirnforschung Steiermark MIND & BRAIN Symposium; DEC 2, 2024; Graz, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212415-14051", "212415-14085" ], "persons": [ "212415-104619", "212415-107891", "212415-66708" ], "imported": "2024-12-04T09:41:34+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212479, "title": "US Imaging of the urogenital tract in neonates and infants: Urogenital tract US - acquired disease in neonates and infants with focus on urinary tract infection and VUR particularly in infants.", "abstract": null, "authors": [ "Riccabona, M" ], "year": 2024, "source": "Neonatal Ultrasound Course, Why, how and when an ultrasound image; MAR 21, 2024; Florence, Italy. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212479-14106" ], "persons": [ "212479-51373" ], "imported": "2024-12-09T11:08:07+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212482, "title": "US Imaging of the urogenital tract in neonates and infants: Urogenital tract US in neonates and infants - interactive case discussion.", "abstract": null, "authors": [ "Riccabona, M" ], "year": 2024, "source": "Neonatal Ultrasound Course, Why, how and when an ultrasound image; MAR 21, 2024; Florence, Italy. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212482-14106" ], "persons": [ "212482-51373" ], "imported": "2024-12-09T11:18:24+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212508, "title": "Bio-psycho-soziale Melanomforschung: \r\nZusammenhänge zwischen chronischem Stress, sozialer Isolation, Mikrobiom und Krebs.\r\n", "abstract": null, "authors": [ "Richtig, E", "Mahnert, A", "Kumpitsch, C", "Binder, L", "Constantini-Kump, P.\r\n" ], "year": 2024, "source": "Gemeinsam\r\nbio-psycho-sozial\r\nResilienz und soziale Unterstützung; Dez 6, 2024; Klagenfurt, Austria. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212508-14023", "212508-14047", "212508-14081" ], "persons": [ "212508-100035", "212508-52274", "212508-65139", "212508-84770", "212508-99612" ], "imported": "2024-12-11T10:10:32+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212510, "title": "Radiological Basics of Lungsonography and HRCT in ILD", "abstract": null, "authors": [ "Talakic, E" ], "year": 2024, "source": "TTT Workshop ILD; DEC 10, 2024; Graz, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212510-14104" ], "persons": [], "imported": "2024-12-11T12:02:51+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212418, "title": "Behandlung von Essstörungen.", "abstract": null, "authors": [ "Reininghaus, EZ" ], "year": 2024, "source": "Vernetzungstreffen: Essstörungen; NOV 8,2024; Graz, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212418-29444" ], "persons": [ "212418-50654" ], "imported": "2024-12-04T12:51:07+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": true, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 212481, "title": "US Imaging of the urogenital tract in neonates and infants: Urogenital tract US in infancy: what to do with neonatally diagnosed conditions for follow-up? Imaging algorithms and beyond.", "abstract": null, "authors": [ "Riccabona, M" ], "year": 2024, "source": "Neonatal Ultrasound Course, Why, how and when an ultrasound image; MAR 21, 2024; Florence, Italy. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212481-14106" ], "persons": [ "212481-51373" ], "imported": "2024-12-09T11:16:43+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212474, "title": "Reconstruction of Brachial Plexus Lesions in the Elderly – a Case Series.", "abstract": null, "authors": [ "Smolle, C", "Geißler, JC", "Kerbl, S", "Girsch, W" ], "year": 2024, "source": "FESSH 2024; JUN 26-29, 2024; Rotterdam, NETHERLANDS. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212474-14076" ], "persons": [ "212474-97446", "212474-111367", "212474-70620" ], "imported": "2024-12-09T09:38:09+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212322, "title": "Wichtige ZNS-Auffälligkeiten.", "abstract": null, "authors": [ "Klaritsch, P" ], "year": 2024, "source": "Ultraschall Update 8; SEP 13-14, 2024; Seggau, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212322-14064" ], "persons": [ "212322-50155" ], "imported": "2024-11-29T21:05:57+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212321, "title": "Selektive Wachstumsrestriktion bei monochorialen Gemini: Diagnostik und Management.", "abstract": null, "authors": [ "Klaritsch, P" ], "year": 2024, "source": "11. Deutsch-Österreichisches Symposium Pränataldiagnostik; JUL 5-6, 2024; Berchtesgaden, GERMANY. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212321-14064" ], "persons": [ "212321-50155" ], "imported": "2024-11-29T21:03:32+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212289, "title": "Kathetergestützte Applikation von Hyaluronidase nach Hyaluronsäureinduzierter Ischämie der oberen Extremität – ein Fallbericht.", "abstract": null, "authors": [ "Hasiba-Pappas, S", "Winter, R", "Kamolz, LP, Rappl, T", "Brodmann, M", "Schweiger, L", "Pal, A" ], "year": 2024, "source": "ÖGPÄRC\r\n62. Jahrestagung\r\nTA PANTA RHEI – ALLES FLIESST; OCT 3-5, 2024; Linz, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212289-14076" ], "persons": [ "212289-56922", "212289-63389", "212289-80111" ], "imported": "2024-11-27T11:32:23+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212262, "title": "Falldemonstrationen.", "abstract": null, "authors": [ "Leithner, A" ], "year": 2024, "source": "DGOOC Tumor Kurs; NOV 7-9, 2024; Berlin, GERMANY. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212262-14052" ], "persons": [ "212262-53237" ], "imported": "2024-11-25T13:25:30+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212191, "title": "Fragmentomics in focus: how urine collection shapes liquid biopsy analysis.", "abstract": null, "authors": [ "Moser, T", "Moser, MJ", "Eberhard, A", "Ziegler, L", "Bauernhofer, T", "Heitzer E" ], "year": 2024, "source": "EACR - Liquid Biopsies; NOV 12-14, 2024; Lyon, FRANCE. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212191-14021", "212191-14085" ], "persons": [ "212191-120331", "212191-50899", "212191-51692", "212191-76215" ], "imported": "2024-11-19T14:25:44+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 212142, "title": "RSV AND INFLUENZA DURING THE COVID-19 PANDEMIC - A TWO-CENTER EXPERIENCE (RICO STUDY)", "abstract": null, "authors": [ "Sever-Yildiz, G", "Kurz, H", "Kocsisek, CV", "Resch, E", "Großschädl, C", "Totschnig, L", "Resch, B," ], "year": 2024, "source": "https://2024.espidmeeting.org/past-abstracts/. 2024; -42nd Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID); May 20-24, 2024; Copenhagen, DENMARK. ", "category": 2, "document_type": 27, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "212142-14094" ], "persons": [ "212142-51743", "212142-112151" ], "imported": "2024-11-17T02:08:54+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 211964, "title": "In-host evolution of Burkholderia pseudomallei.", "abstract": "Burkholderia pseudomallei is a gram-negative rod-shaped bacterium responsible for the severe disease melioidosis. B. pseudomallei has the capability to infect both non-phagocytic and phagocytic cells and has evolved several mechanisms to evade the host immune system. A previous study identified a B. pseudomallei isolate, which showed altered survival within macrophages compared to its isogenic wildtype after passage through human macrophages. The aim of this study was to further characterize the virulence of this isolate (E8_evolved) and to elucidate the underlying mechanisms. B. pseudomallei E8_evolved exhibited increased intracellular invasion and cytotoxicity compared to the isogenic wildtype. This suggests a potentially increased invasion or improved phagosomal escape, potentially leading to a higher bacterial load early in the infection. To determine whether pyroptosis is responsible for the observed increase in cytotoxicity, western blot analyses were performed. The cleavage product of gasdermin D, an indicator of pyroptosis, was detected at a similar intensity in E8_evolved and the wildtype strain. Next caspase-1 and caspase-4, which activate gasdermin D during canonical or non-canonical inflammasome activation, were investigated. While caspase-1 cleavage was similar in both strains, the caspase-4 cleavage product showed increased intensity in E8_evolved indicating increased activation. As no phosphorylated MLKL was detected, necroptosis can be excluded as a potential cause of cell lysis. Additionally, it was observed that the increased cytotoxicity is not associated with elevated production and secretion of the cytokines TNF-α, IL-1α, and IL-1β. Specifically, the concentration of the cytokine TNF-α is reduced in the mutant strain three hours post-infection. To explore changes at the DNA level, a whole genome sequencing analysis of the mutant strain was conducted. This analysis revealed two mutations in the potential T3SS regulatory protein HpaA, specifically in the amino acids VAL25 and ARG28. However, since this protein remains uncharacterized, further research is required to fully understand its role and validate the potential impact of these mutations. Taken together, the mutant exhibits enhanced invasion and bacterial loads, potentially attributable to mutations in the putative T3SS regulatory protein HpaA.", "authors": [ "Harlander, J" ], "year": 2024, "source": " [ Diplomarbeit/Master Thesis (UNI) ] Universität Graz; 2024. pp.57. ", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2024-11-07T09:18:56+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 211951, "title": "Vascular, cardiometabolic and immunovirological changes in people living with HIV: Longitudinal data analysis from the EndoAfrica Study, South Africa", "abstract": null, "authors": [ "Strijdom, H", "de Boever, P", "Kessler, HH", "Stelzl, E", "Webster, I", "Everson, F", "Goswami, N" ], "year": 2024, "source": "Clin Chem Lab Med; Congress Abstracts. 2024; 62(6):eA188-eA211.-ISMD2024 Thirteenth International Symposium on\r\nMolecular Diagnostics; JUN 13-14, 2024; Graz, AUSTRIA. ", "category": 2, "document_type": 9, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "211951-14010", "211951-14023" ], "persons": [ "211951-57932", "211951-50514", "211951-51812" ], "imported": "2024-11-06T11:43:20+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true } ] }