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GET /v1/research/publication/?format=api&offset=151420&ordering=impactfactor
{ "count": 156944, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=151440&ordering=impactfactor", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=151400&ordering=impactfactor", "results": [ { "id": 156266, "title": "Survival analysis of 998 Corail® stems implanted at the Department of Orthopaedic Surgery,Medical University of Graz, from 2005 to 2012", "abstract": "Background: The first implantation of the Corail® hip system was performed in 1986 by the French “ATRO-Groupe”. Till 2012, more than 1.000.000 Corail® implants have been sold worldwide since introduction. Meanwhile, this hydroxyapatite (HA) coated stem is established worldwide by excellent long-term results.\nThe aim of this retrospective study was the clinical evaluation and site analysis for the HA coated Corail® stem, which was in use since 2005 at the Department of Orthopaedic Surgery, Medical University of Graz.\nPatients and methods: From January 2005 to December 2012, 891 patients, 408 men and 483 women, were identified and included in this study. Within this collective, 998 Corail® stems were implanted. The average age of patients at the time of surgery was 63 years (range, 18-91 years). The mean postoperative radiological follow-up of all patients together was 45 months (range, 3-128 months). Three months postoperatively, 807 patients were available for clinical and radiological follow-up, whereas the number of participants was decreasing during the time of follow-up (e.g. 724 patients after 6 months and 668 patients after one year). The assessment of the radiographs included leg length differences, sign of stress shielding, lysis, heterotopic ossification according to the classification of Brooker, bone resorption rated in Gruen zones and the implant position. An implant survival for aseptic loosening as well as any reason for revision as endpoint was done using the Kaplan-Meier method.\nResults: In 75% of the cases a standard Corail® stem was implanted, followed by the Corail® high offset stem (21%) and the coxa vara stem (4%). The Corail® stem was combined with a Pinnacle® cup in 93%. The most common bearing used was ceramic-on-ceramic (n=873, 88%) with the head size 36 mm (75%). Heterotopic ossification was observed in 52 patients (5.2%) and clinically irrelevant radiographic loosening lines in 166 patients.\nFive out of 912 Corail® stems implanted, had to be revised due to aseptic loosening \n(= revision rate: 0.5%). According to the method of Kaplan-Meier, the survival of the implant was 99% at 5 years and 97.6% after 10 years. Eleven other stem revisions had to be made due to periprosthetic fractures (=1.1%).\nConclusion: The results of our study showed excellent clinical results and minimal risk for aseptic loosening of the Corail® stem compared with international registry data. The number of early periprosthetic fractures was stated to be part of a kind of learning curve and was eliminated by adapting the implantation technique. In different register data such as Australia, New Zealand, Denmark and England, an implant survival for the Corail® stem was reported from 97% to 99% after a follow-up up to15 years.\n", "authors": [ "Maier, M" ], "year": 2016, "source": "Humanmedizin; [ Diplomarbeit ] Graz Medical University; 2016. pp. ", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2016-12-07T11:53:56+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Graz Medical University", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 156267, "title": "Characterization of novel predictive biomarkers in colorectal cancer", "abstract": "MicroRNAs (miRNAs) are small, non-coding, single-stranded RNAs that are known to be important regulators of carcinogenesis and might be useful potential prognostic factors and therapeutic targets in colorectal cancer (CRC). In the current study we focused on two specific miRNAs, namely miR-196b-5p and miR-188-3p, and analysed their role as potential prognostic biomarkers, their biological functions and their molecular mechanisms of action.\nIn the first part of this study miR-196b-5p expression was quantified by qRT-PCR in two independent cohorts comprising 292 CRC patients in total to investigate its potential as biomarker. In the second part of this thesis an analysis of genome-wide miRNA sequencing data of 228 CRC patients from the cancer genome atlas (TCGA) was performed and identified miR-188-3p as significantly associated with survival. This observation was further validated in a large independent validation cohort (n=332). Transient and stable gain and loss of function experiments were performed in a panel of CRC cell lines, to evaluate the impact of miR-196b-5p and miR-188-3p on proliferation, chemo-sensitivity, migration, invasion and metastases formation in vitro and in vivo. The molecular pathways influenced by these miRNAs were characterized using mRNA transcriptome profiling, in silico target prediction tools, luciferase-interaction assays and pheno-copy gene knock-down experiments.\nLow miR-196b-5p expression was significantly associated with metastases and poor survival in both independent CRC patient cohorts (p<0.05). Inhibition of miR-196b-5p resulted in increased cancer cell migration/invasion and metastases formation in nude mice (p<0.05). We showed that HOXB7 and GalNT5 mRNAs are regulated by miR-196b-5p via targeting their 3´UTR, which in turn led to a decrease of CRC cell migration. We identified high miR-188-3p expression as an independent prognostic factor (screening cohort: hazard ratio = 4.137, 95%CI=1.568-10.917, p=0.004; validation cohort: hazard ratio HR=1.538, 95%CI=1.107-2.137, p=0.010, respectively). Enhanced miR-188-3p expression resulted in increased migratory behavior of CRC cells in vitro and metastases formation in vivo (p<0.05). The pro-migratory phenotype of miR-188-3p is regulated by direct interaction with MLLT4, a novel migration related gene in CRC. \nIn conclusion, the results of this thesis suggest that miR-196b-5p and miR-188-3p are novel independent prognostic factors in CRC patients which can be party explained by the direct interaction with genes involved in cancer cell migration.\n", "authors": [ "Stiegelbauer, V" ], "year": 2016, "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Graz Medical University; 2016. pp. ", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2016-12-07T11:53:56+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Graz Medical University", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 156269, "title": "Carotid Surgery in Octogenarian Women?", "abstract": null, "authors": [ "Cohnert, T" ], "year": 2016, "source": "6th Munich Vascular Conference 2016; DEC 1-3, 2016; Munich, GERMANY. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156269-14045" ], "persons": [ "156269-50860" ], "imported": "2016-12-07T14:19:15+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156270, "title": "Vitamin D in critically ill patients", "abstract": null, "authors": [ "Amrein, K." ], "year": 2016, "source": "ICS SOA ; DEC 5-7, 2016; London, UK. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156270-14080" ], "persons": [ "156270-58615" ], "imported": "2016-12-07T14:50:21+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156271, "title": "Entwicklung eines Elternfragebogens zur Kleinkindernährung von Kindern im häuslichen Umfeld.", "abstract": null, "authors": [ "Stainer, B" ], "year": 2015, "source": " [ Diplomarbeit/Master Thesis (FH) ] FH Joanneum; 2015. ", "category": 5, "document_type": 28, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2016-12-07T15:43:42+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "FH JOANNEUM - University of Applied Sciences", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 156272, "title": "Der kindliche Notfall im Schockraum - worauf kommt es an?", "abstract": null, "authors": [ "Warncke, G" ], "year": 2014, "source": "10. Rostocker Intensivpflegetag; SEP 30, 2014; Rostock, GERMANY. 2014. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156272-14049" ], "persons": [], "imported": "2016-12-07T20:19:30+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 156273, "title": "Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy.", "abstract": null, "authors": [ "Hoenigl, M", "de Oliveira, MF", "Pérez-Santiago, J", "Zhang, Y", "Woods, SP", "Finkelman, M", "Gianella, S" ], "year": 2015, "source": "GMS Infect Dis. 2015; 3(1):", "category": 1, "document_type": 1, "sci": null, "pubmed": "27917362", "doi": "10.3205/id000018", "pmc": "PMC5132183", "organizations": [ "156273-14087" ], "persons": [ "156273-64754-2" ], "imported": "2016-12-07T01:00:00+01:00", "journal": "GMS Infect Dis", "issn": "2195-8831", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156277, "title": "Instrumente zur Ermittlung des Ernährungszustandes (Messmethoden/Perzentilen)", "abstract": null, "authors": [ "Hauer A.C." ], "year": 2016, "source": "NutriPäd-Seminar der GPGE; NOV 21-22, 2016; Fulda, GERMANY. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156277-14091" ], "persons": [ "156277-51968" ], "imported": "2016-12-09T09:57:07+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156278, "title": "„Diarrhoe und Obstipation bei Kindern und Jugendlichen – klinisches Alarmsymptom oder funktionelle Störung“?", "abstract": null, "authors": [ "Hauer A.C." ], "year": 2016, "source": "47. Kongress für Allgemeinen Medizin; NOV 24, 2016; Graz, AUSTRIA. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156278-14091" ], "persons": [ "156278-51968" ], "imported": "2016-12-09T09:58:47+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156279, "title": "Obstipation im Kindesalter: Diagnostik und Therapie", "abstract": null, "authors": [ "Hauer A.C." ], "year": 2016, "source": "Pädiatrie Update Refresher; NOV 25, 2016; Wien, AUSTRIA. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156279-14091" ], "persons": [ "156279-51968" ], "imported": "2016-12-09T10:00:18+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156280, "title": "Das Reizdarmsyndrom im Kindes- und Jungendalter", "abstract": null, "authors": [ "Hauer A.C." ], "year": 2016, "source": "Pädiatrie Update Refresher; NOV 25, 2016; Wien, AUSTRIA. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156280-14091" ], "persons": [ "156280-51968" ], "imported": "2016-12-09T10:02:12+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156286, "title": "Biobank Graz: The Hub for Innovative Biomedical Research", "abstract": null, "authors": [ "Huppertz,B", "Bayer, M", "Macheiner.T", "Sargsyan, K." ], "year": 2016, "source": "Open Journal of Bioresouces. 2016; 3(1): e3", "category": 1, "document_type": 1, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156286-28392", "156286-29444" ], "persons": [ "156286-54033", "156286-54142" ], "imported": "2016-12-10T07:55:11+01:00", "journal": "Open Journal of Bioresouces", "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": true, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156289, "title": "NIRS during neonatal transition and resuscitation ", "abstract": null, "authors": [ "Pichler, G, 2016 \r\n\r\n" ], "year": 2016, "source": "Clinical Immersion On NIRS; DEZ 6-7, 2016; Graz, AUSTRIA. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156289-14094" ], "persons": [ "156289-50907" ], "imported": "2016-12-11T13:03:49+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": false, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156290, "title": "Zerebrale Oxygenierung unmittelbar nach Geburt", "abstract": null, "authors": [ "Pichler, G" ], "year": 2016, "source": "Abstraktband. 2016; -Neue Möglichkeiten der Bildgebung\r\nin der Neonatologie; OKT 8, 2016; Gießen, GERMANY. ", "category": 2, "document_type": 19, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156290-14094" ], "persons": [ "156290-50907" ], "imported": "2016-12-11T13:06:28+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156292, "title": "Die Wertigkeit des Toronto Clinical Neuropathy Scoring System für die Polyneuropathie-Diagnose bei idiopathischem Parkinsonsyndrom", "abstract": null, "authors": [ "Sonieva, D", "Ablinger, G", "Hofer, E", "Culea, V", "Kögl-Wallner, M", "Seel, W", "Hochmeister, S", "Homann, CN\r\n" ], "year": 2016, "source": "Jahrestagung der Österreichischen Parkinsongesellschaft ; OKT 20-22, 2016; Graz, AUSTRIA. 2016. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "156292-14026", "156292-14051" ], "persons": [ "156292-51959", "156292-58284", "156292-77129" ], "imported": "2016-12-12T12:22:39+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 156294, "title": "Extremity Vascular Trauma With Respect to Differences between Upper and Lower Limbs.", "abstract": null, "authors": [ "Hohenberger, GM", "Konstantiniuk, P", "Cambiaso Daniel, J", "Matzi, V", "Schwarz, AM", "Krassnig, R", "Holzapfel, GA", "Regittnig, P", "Cohnert, TU" ], "year": 2016, "source": "Doctoral Day of the Medical University of Graz 2016; DEC 14, 2016; Graz, AUSTRIA. 2016. 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