Publication List
List publications.
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id (integer)
Primary key.
name (string)
Name of doctoral school.
emails (string[])
Contact emails.
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year:gt,gte,lt,ltesci:iexact,contains,icontains,startswith,istartswithpubmed:iexact,contains,icontains,startswith,istartswithdoi:iexact,contains,icontains,startswith,istartswithpmc:iexact,contains,icontains,startswith,istartswithorganization_authorship:inimpact:isnull,gt,gte,lt,lteimported:isnull,gt,gte,lt,lte,date
GET /v1/research/publication/?format=api&offset=151220&ordering=-imported
{ "count": 156991, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=151240&ordering=-imported", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=151200&ordering=-imported", "results": [ { "id": 66360, "title": "The effect of high-dose peroral zidovudine treatment in a 4-year-old child with HIV encephalopathy", "abstract": null, "authors": [ "Zenz, W", "Lackner, H", "Maurer, U", "Ranner, G", "Puchhammer-Stöckl, E" ], "year": 1992, "source": "Padiatr Padol. 1992; 27(1):11-15", "category": 1, "document_type": 1, "sci": null, "pubmed": "1560990", "doi": null, "pmc": null, "organizations": [], "persons": [ "66360-51647-1" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Padiatr Padol", "issn": "0030-9338", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": true, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66343, "title": "Assessment of a commonly available latex particle agglutination test in rapid, bacteriologic cerebrospinal fluid diagnosis", "abstract": null, "authors": [ "Grubbauer, HM", "Dornbusch, HJ", "Zobel, G", "Thiel, W" ], "year": 1988, "source": "Padiatr Padol. 1988; 23(1): 39-45. ", "category": 1, "document_type": 1, "sci": null, "pubmed": "3133628", "doi": null, "pmc": null, "organizations": [], "persons": [ "66343-51736-6" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Padiatr Padol", "issn": "0030-9338", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66338, "title": "Rapid detection of selected aneuploidies by quantitative fluorescent PCR.", "abstract": null, "authors": [ "Adinolfi, M", "Sherlock, J", "Pertl, B" ], "year": 1995, "source": "Bioessays. 1995; 17(7): 661-664. ", "category": 1, "document_type": 1, "sci": "ISI:A1995RJ40200011", "pubmed": "7646488", "doi": "10.1002/bies.950170712", "pmc": null, "organizations": [ "66338-14038" ], "persons": [ "66338-51719-6" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Bioessays", "issn": "0265-9247", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 5.576, "impactfactor_year": 1995, "impactfactor_norm": 0.96969696969697, "impactfactor_norm_year": 1998, "impactfactor_norm_category": "BIOLOGY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 66341, "title": "The pregnant patient in dental care. Survey results and therapeutic guidelines", "abstract": null, "authors": [ "Pertl, C", "Heinemann, A", "Pertl, B", "Lorenzoni, M", "Pieber, D", "Eskici, A", "Amann, R" ], "year": 2000, "source": "Schweiz Monatsschr Zahnmed. 2000; 110(1): 37-46. ", "category": 1, "document_type": 1, "sci": null, "pubmed": "10670275", "doi": null, "pmc": null, "organizations": [ "66341-14022", "66341-14038" ], "persons": [ "66341-51703-6", "66341-51719-2", "66341-51756-6" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Schweiz Monatsschr Zahnmed", "issn": "1011-4203", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 66337, "title": "Detection of fetal cells in endocervical samples.", "abstract": null, "authors": [ "Pertl, B", "Davies, A", "Soothill, P", "Rodeck, C", "Adinolfi, M" ], "year": 1994, "source": "Ann N Y Acad Sci. 1994; 731(7): 186-192. ", "category": 1, "document_type": 1, "sci": "ISI:A1994BB36A00026", "pubmed": "7944117", "doi": "10.1111/j.1749-6632.1994.tb55768.x", "pmc": null, "organizations": [], "persons": [ "66337-51719-2" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Ann N Y Acad Sci", "issn": "0077-8923", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 0.868, "impactfactor_year": 1994, "impactfactor_norm": 0.827160493827161, "impactfactor_norm_year": 1998, "impactfactor_norm_category": "MULTIDISCIPLINARY SCIENCES", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66400, "title": "Three-dimensional morphological characterization of optic nerve fibers by atomic force microscopy and by scanning electron microscopy.", "abstract": null, "authors": [ "Melling, M", "Karimian-Teherani, D", "Mostler, S", "Hochmeister, S" ], "year": 2005, "source": "Microsc Microanal. 2005; 11(4): 333-340. ", "category": 1, "document_type": 1, "sci": "ISI:000230376900006", "pubmed": "16079017", "doi": "10.1017/S1431927605050245", "pmc": null, "organizations": [], "persons": [ "66400-58284-6" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Microsc Microanal", "issn": "1431-9276", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 1.878, "impactfactor_year": 2005, "impactfactor_norm": 0.555555555555556, "impactfactor_norm_year": 2005, "impactfactor_norm_category": "MICROSCOPY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66339, "title": "Value of ultrasound in early detection of endometrial carcinoma", "abstract": null, "authors": [ "Pertl, B", "Lahousen, M", "Pieber, D", "Heydarfadai, HJ", "Giuliani, A" ], "year": 1996, "source": "Gynakol Geburtshilfliche Rundsch. 1996; 36(1):14-20", "category": 1, "document_type": 1, "sci": "ISI:A1996UR52000004", "pubmed": "8737518", "doi": "10.1159/000272606", "pmc": null, "organizations": [ "66339-14038" ], "persons": [ "66339-51719-2" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Gynakol Geburtshilfliche Rundsch", "issn": "1018-8843", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 0.055, "impactfactor_year": 1996, "impactfactor_norm": 0.0188679245283019, "impactfactor_norm_year": 1998, "impactfactor_norm_category": "OBSTETRICS & GYNECOLOGY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 66399, "title": "3-D morphological characterization of the liver parenchyma by atomic force microscopy and by scanning electron microscopy.", "abstract": null, "authors": [ "Melling, M", "Karimian-Teherani, D", "Mostler, S", "Behnam, M", "Hochmeister, S" ], "year": 2004, "source": "Microsc Res Tech. 2004; 64(1): 1-9. ", "category": 1, "document_type": 1, "sci": "ISI:000223220700001", "pubmed": "15287013", "doi": "10.1002/jemt.20045", "pmc": null, "organizations": [], "persons": [ "66399-58284-6" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Microsc Res Tech", "issn": "1059-910X", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 2.609, "impactfactor_year": 2004, "impactfactor_norm": 1.0, "impactfactor_norm_year": 2004, "impactfactor_norm_category": "MICROSCOPY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66440, "title": "Gene therapy progress and prospects: stem cell plasticity.", "abstract": null, "authors": [ "Kashofer, K", "Bonnet, D" ], "year": 2005, "source": "Gene Ther. 2005; 12(16): 1229-1234. ", "category": 1, "document_type": 3, "sci": "ISI:000231019700001", "pubmed": "15973440", "doi": "10.1038/sj.gt.3302571", "pmc": null, "organizations": [], "persons": [ "66440-57386-1" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Gene Ther", "issn": "0969-7128", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 4.836, "impactfactor_year": 2005, "impactfactor_norm": 0.906474820143885, "impactfactor_norm_year": 2005, "impactfactor_norm_category": "BIOTECHNOLOGY & APPLIED MICROBIOLOGY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66397, "title": "Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.", "abstract": null, "authors": [ "Hochmeister, S", "Grundtner, R", "Bauer, J", "Engelhardt, B", "Lyck, R", "Gordon, G", "Korosec, T", "Kutzelnigg, A", "Berger, JJ", "Bradl, M", "Bittner, RE", "Lassmann, H" ], "year": 2006, "source": "J Neuropathol Exp Neurol. 2006; 65(9): 855-865. ", "category": 1, "document_type": 1, "sci": "ISI:000241692400003", "pubmed": "16957579", "doi": "10.1097/01.jnen.0000235119.52311.16", "pmc": null, "organizations": [], "persons": [ "66397-58284-1" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "J Neuropathol Exp Neurol", "issn": "0022-3069", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 4.371, "impactfactor_year": 2006, "impactfactor_norm": 0.96969696969697, "impactfactor_norm_year": 2005, "impactfactor_norm_category": "PATHOLOGY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66441, "title": "In vivo formation of unstable heterokaryons after liver damage and hematopoietic stem cell/progenitor transplantation.", "abstract": null, "authors": [ "Kashofer, K", "Siapati, EK", "Bonnet, D" ], "year": 2006, "source": "Stem Cells. 2006; 24(4): 1104-1112. ", "category": 1, "document_type": 1, "sci": "ISI:000240636300033", "pubmed": "16282440", "doi": "10.1634/stemcells.2005-0405", "pmc": null, "organizations": [], "persons": [ "66441-57386-1" ], "imported": "2007-02-28T01:00:00+01:00", "journal": "Stem Cells", "issn": "1066-5099", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 7.924, "impactfactor_year": 2006, "impactfactor_norm": 0.956834532374101, "impactfactor_norm_year": 2005, "impactfactor_norm_category": "BIOTECHNOLOGY & APPLIED MICROBIOLOGY", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66335, "title": "Suprakondyläre Humerusfrakturen im Kindesalter: ein biomechanischer Vergleichstest von 4 Osteosyntheseverfahren", "abstract": null, "authors": [ "Castellani, C", "Weinberg, AM", "Arzdorf, M", "Schneider, E", "Gasser, B", "Linke, B" ], "year": 2006, "source": "Gemeinsamer Kongress DGOOC-DGU-BVO; OKT 2-10, 2006; Berlin. 2006. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "66335-14049" ], "persons": [ "66335-50785", "66335-54087" ], "imported": "2007-02-27T18:08:26+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 66334, "title": "Molecular-cytogenetic analysis of chromosomal imbalances in solid tumors: Relevance to diagnosis and therapy", "abstract": null, "authors": [ "Ullmann, R" ], "year": 2000, "source": " [ Dissertation ] University of Salzburg; 2000. pp.95. ", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2007-02-27T18:01:23+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "University of Salzburg", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66333, "title": "Suprakondylar Humerus Fractures in Children: a Biomechanical Analysis of Four Methods for Osteosynthesis", "abstract": null, "authors": [ "Castellani, C", "Weinberg, AM", "Arzdorf, M", "Schneider, E", "Gasser, B", "Linke, B" ], "year": 2006, "source": "EORS; JUN 7-9, 2006; Bologna. 2006. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "66333-14049" ], "persons": [ "66333-50785", "66333-54087" ], "imported": "2007-02-27T18:01:17+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 66332, "title": "Untersuchung chromosomaler Aberrationen im tumorassoziierten Stroma des Plattenepithelkarzinoms der Lunge im Hinblick auf eine mögliche Einflußnahme auf die Kanzerogenese", "abstract": "Ziel der vorliegenden Arbeit war die Untersuchung chromosomaler Veränderungen im tumorassoziierten Stroma des Plattenepithelkarzinoms der Lunge in Hinblick auf eine mögliche Einflussnahme auf die Karzinogenese. Es wurden 14 Plattenepithelkarzinome und ihr assoziiertes Stroma mittels Lasermikrodissektion, DOP-PCR und Comparativer Genomischer Hybridisierung (CGH) getrennt analysiert. Die in den Tumoren gefundenen Veränderungen sind mit den aus der Literatur bekannten vergleichbar, im tumornahem Stroma konnten keine chromosomalen Aberrationen detektiert werden. Um der Frage nachzugehen, ob das tumornahe Parenchym Stress-auslösenden Karzinogenen ausgesetzt ist, wurden der Tumor und sein benachbartes Stroma mittels Immunhistochemie untersucht, und die Expression von Hitzeschockproteinen (HSPs) und Glutathion-S-Transferasen (GSTs) mit normalem Epithel und Stroma verglichen. Die meisten Antikörper, z.B. GST mu oder GST pi, zeigten im desmoplastischen (tumornahen) Parenchym deutlich höhere Konzentrationen, als im histologisch normalen, nicht veränderten Stroma. Daraus entstand die Hypothese, dass intaktes Epithel in gewissem Maß in der Lage ist als Barriere gegen karzinogene Substanzen zu fungieren. Entweder diese Barrierefunktion versagt beim Karzinom, oder der Tumor produziert selbst Metabolite die im tumoassoziierten Stroma eine erhöhte Stressbelastung auslösen. Diese Studie unterstreicht die Wichtigkeit anderer Faktoren als chormosomaler Imbalanzen für die Entstehung morphologischer Veränderungen im tumorassoziierten Stroma. Ausgehend von den Ergebnissen der CGH scheint die Rolle chormosomaler Aberrationen im Stroma für die Entstehung des Platteneptihelkarzinoms der Lunge fraglisch.", "authors": [ "Petautschnigg, U" ], "year": 2004, "source": "[ Dissertation ] Universität Graz; 2003. pp.47. ", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2007-02-27T17:58:15+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66331, "title": "Cell proliferation analysis in sarcoidosis lavage cells", "abstract": "Until today the causes and triggers of sarcoidisis are not identified. Subject of this study was to analyse genes of the proliferation-pathway via PI3K and Akt. This investigation was bases on the consideration that enhanced proliferation might be responsible for the presence of immunocompetent cells in sarcoidosis. Using real-time PCR, we were able to find out that genes of this pathway are not overexpressed, except of one catalytic subunit of PI3K. Therefore we assumed that there is a proliferation stimulus primary aiming onto another pathway. Additionally, we found evidence that apoptosis is inhibited.", "authors": [ "Markert, E" ], "year": 2004, "source": "[ Dissertation ] University of Graz; 2003. pp.42. ", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2007-02-27T17:54:45+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "University of Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66330, "title": "Becherzellproliferation in der Congenitalen Cystischen Adenomatoiden Malformation (CCAM)", "abstract": "CCAM, die Congenitale Cystische Adenomatoide Malformation, ist eine seltene Erkrankung der kindlichen Lunge. Bei der histologischen Untersuchung dieser Zysten fallen manchmal polsterförmige Becherzellproliferationen auf. Diese Becherzellen weisen Kernatypien auf. In der Literatur sind Assoziationen der CCAM mit Adenokarzinomen und Rhabdomyosarkomen beschrieben worden.\r\n\r\nZiel dieser Studie war es, das Epithel der CCAM, das umgebende Normalgewebe und soweit vorhanden die (prä-) kanzeröse Läsion auf chromosomale Aberrationen hin zu untersuchen. \r\n\r\nFür die Studie wurde formalinfixiertes, in Paraffin eingebettetes Material verwendet, das im Rahmen des European Project on Rare Pulmonary Diseases, Grant Agreement No SI12.323154, 2001CVG4-801) zusammengetragen worden war. Einige dieser Fälle waren mit atypischen Becherzellpoliferationen, einem Bronchioloalveolären Karzinom oder einem Adenokarzinom vergesellschaftet. Die Fälle wurden mittels CGH (Comparativer Genomischer Hybridisierung) untersucht.\r\n\r\nBei 22 Fällen, die erfolgreich untersucht wurden, konnten weder im Epithel der CCAM noch im Normalgewebe chromosomale Aberrationen detektiert werden. Jedoch fanden sich in den beiden Becherzellproliferaten, die erfolgreich untersucht wurden, Aberrationen (Gewinne auf den Chromosomen 2 und 4), die sich nebst anderen Aberrationen auch beim Adenokarzinom und beim Bronchioloalveolären Karzinom wieder finden ließen.\r\n\r\nSofern es die kleine Fallzahl erlaubt, lässt sich eine Becherzellproliferation-Karzinom-Sequenz erkennen, wobei es sich bei den initialen Aberrationen um die Gewinne auf den Chromosomen 2 und 4 handeln dürfte.\r\n\r\nDass keine Aberrationen im CCAM-Epithel und im Normalgewebe detektiert werden konnten, verdeutlicht, dass es ich bei der Pathogenese dieser Malformation nicht um eine Keimbahnmutation handelt. Wahrscheinlich kommt es im Rahmen der organogenese aufgrund eines lokalisierten regulativen Prozesses zur Bildung dieser zystischen Strukturen.\r\n\r\nMöglicherweise werden im Epithel der CCAM bestimmte Zytokine überexprimiert, die in weiterer Folge zu Entstehung von Becherzellproliferationen führen, die bereits Chromosomenaberrationen aufweisen. Dass die gleichen Aberrationen auch bei Adenokarzinomen festzustellen sind, lässt den Schluss zu, dass es sich bei den Becherzellproliferationen um eine Präneoplasie des Adenokarzinoms handelt.\r\n", "authors": [ "Stacher, E" ], "year": 2003, "source": "[ Dissertation ] Universität Graz; 2003. pp.69. ", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "66330-14020" ], "persons": [], "imported": "2007-02-27T17:51:18+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 66329, "title": "Genetische Aberrationen in Sarcomatoiden Lungentumoren", "abstract": "Der größte Teil der Lungentumore (mehr als 99%!!) ist epithelialen Ursprungs. Unter diesen ist auch die Gruppe der sarcomatoiden Karzinome (SC) vertreten. Das besondere bei diesen Tumoren ist, dass sie morphologisch aus 2 verschiedenen Phänotypen bestehen. Neben den typischen epithelialen Tumorzellen kommen Zellen vor, die einen mesenchymalen Phänotyp nachahmen. Zur genetischen Analyse der SC haben wir 23 Fälle mittels der Comparativen Genomischen Hybridisierung untersucht. Die CGH ist eine Screening-Methode zur Detektion chromosomaler Imbalanzen im Tumor-Genom. DNA-Gewinne und Verluste werden dabei innerhalb des Tumors aufgedeckt und für jeden Tumor ein Muster chromosomaler Überrepräsentation und Deletion festgestellt. Folgende Veränderungen traten gehäuft auf: Gewinne auf Chromosom 1q, 3q, 7, 8q, 12p und 19; Verluste waren mengenmäßig selten und traten auf Chromosom 13q und 6q auf. Das Muster der chromosomalen Veränderungen in den SC würde größtenteils für einen monoklonalen Ursprung dieser Tumore sprechen. Als Ausnahme muss man das Blastom anführen. Dieser Tumor scheint eine eigene Entität darzustellen. Weiters untersuchten wir mit Immunhistochemischen Färbungen (IGC) das Phänomen der epithelialen, mesenchymalen Transformation (EMT). Es wurde die Hypothese aufgestellt, dass die mesenchymalen Anteile der SC aus den epithelialen hervorgehen. Hier zeigte jedoch die (IHC) keine übereinstimmenden Ergebnisse und es muss davon ausgegangen werden, dass die mesenchymalen Anteile der SC nicht über eine Aktivierung von TGF1/Notch1 und in weiterer Folge über eine Überexpression des Transkriptionsfaktors Snail (klassische EMT) entstehen. Alternativ könnten eine EMT über den Wnt-Signalweg, welcher bei Lungentumoren bisher selten beschrieben wurde, eine Rolle spielen. Zusätzlich könnte eine direkte Aktivierung der Vimentinexpression über c-Jun erfolgen.", "authors": [ "Blaukovitsch, M" ], "year": 2005, "source": "[ Dissertation ] Medizinische Universität Graz; 2005. pp.103. ", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2007-02-27T17:47:05+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Medizinische Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 35993, "title": "Role of microchimerism in the pathogenesis of oral lichen planus.", "abstract": null, "authors": [ "Weger, W", "Bauer, M", "Odell, E", "Pertl, B", "Cerroni, L", "Kerl, H", "Jakse, N", "Pertl, C" ], "year": 2006, "source": "EXP DERMATOL. 2006; 15(2): 125-129. ", "category": 1, "document_type": 1, "sci": "ISI:000234799800006", "pubmed": "16433684", "doi": "10.1111/j.1600-0625.2006.00393.x", "pmc": null, "organizations": [ "35993-14038", "35993-14047", "35993-14057" ], "persons": [ "35993-51751-6", "35993-50153-1", "35993-51620-6", "35993-51707-6", "35993-51719-6" ], "imported": "2007-02-27T17:30:36+01:00", "journal": "EXP DERMATOL", "issn": "0906-6705", "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": 2.449, "impactfactor_year": 2006, "impactfactor_norm": 0.769230769230769, "impactfactor_norm_year": 2005, "impactfactor_norm_category": "DERMATOLOGY, VENERAL DISEASES", "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": true, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": true, "local_affiliation": true }, { "id": 812, "title": "Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients.", "abstract": null, "authors": [ "Wirnsberger, GH", "Pfragner, R", "Mauric, A", "Zach, R", "Bogiatzis, A", "Holzer, H" ], "year": 1998, "source": "TRANSPLANT PROC. 1998; 30(5): 2117-2119. 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