Publication List
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year:gt,gte,lt,ltesci:iexact,contains,icontains,startswith,istartswithpubmed:iexact,contains,icontains,startswith,istartswithdoi:iexact,contains,icontains,startswith,istartswithpmc:iexact,contains,icontains,startswith,istartswithorganization_authorship:inimpact:isnull,gt,gte,lt,lteimported:isnull,gt,gte,lt,lte,date
GET /v1/research/publication/?format=api&offset=149820&ordering=year
{ "count": 157555, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=149840&ordering=year", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=149800&ordering=year", "results": [ { "id": 206879, "title": "Optimizing in vitro modeling of the human gut: exploring microbial dynamics in intestinal health and disease.", "abstract": null, "authors": [ "Zukauskaite, K", "Pacher, C", "Tripolt, S", "Balazs, I", ", Horvath, A", "Stadlbauer, V", "" ], "year": 2024, "source": "Theodor Escherich Symposium; JAN 18-19, 2024; Graz, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206879-14081" ], "persons": [ "206879-112689", "206879-119169", "206879-50989", "206879-81091" ], "imported": "2024-01-23T09:18:35+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": true, "local_affiliation": true }, { "id": 206882, "title": "Frühe Rezidive intrazerebraler Blutungen: Muster, Ursachen und mögliche Konsequenzen", "abstract": null, "authors": [ "Fandler-Höfler, S", "Nash, P", "Obergottsberger, L", "Wünsch, G", "Zhang, W", "Ozkan, H", "Locatelli, M", "Du, Y", "Panteleienko, L", "Mendel, R", "Thiankhaw, K", "Kneihsl, M", "Enzinger, C", "Gattringer, T", "Werring, DJ" ], "year": 2024, "source": "Jahrestagung der österreichischen Schlaganfall-Gesellschaft; Jan 18-19, 2024; Vienna, Austria. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206882-14026", "206882-14051" ], "persons": [ "206882-50173", "206882-50444", "206882-70680", "206882-82411", "206882-83425" ], "imported": "2024-01-23T10:02:23+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 206883, "title": "Ein treuer, zufriedener, komplizierter Kunde", "abstract": null, "authors": [ "Fandler-Höfler, S", "Gattringer, T" ], "year": 2024, "source": "Jahrestagung der österreichischen Schlaganfall-Gesellschaft; Jan 18-19, 2024; Vienna, Austria. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206883-14051" ], "persons": [ "206883-70680", "206883-82411" ], "imported": "2024-01-23T10:04:13+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 206884, "title": "Interpretation und neue Erkenntnisse der ANNEXA-I Studie", "abstract": null, "authors": [ "Fandler-Höfler, S" ], "year": 2024, "source": "Jahrestagung der österreichischen Schlaganfall-Gesellschaft; Jan 18-19, 2024; Vienna, Austria. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206884-14051" ], "persons": [ "206884-82411" ], "imported": "2024-01-23T10:05:11+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 206926, "title": "Exploring functional modulation of T cell subsets by extracellular nucleotides: Differential response in the aged immune system?", "abstract": null, "authors": [ "Rittchen, S", "Zdouc, A", "Angiari, S", "Fessler, J", "" ], "year": 2024, "source": "Harald von Boehmer Midwinter Conference: Advances in Immunobiology; JAN 20-24, 2024; Seefeld, Tirol, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206926-14014" ], "persons": [ "206926-107391", "206926-78952", "206926-95212" ], "imported": "2024-01-25T14:57:14+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 206960, "title": "Neues aus der Wundbehandlung - gepulstes kaltes Rotlicht/Photobiomodulation.", "abstract": null, "authors": [ "Gruber, V", "Binder, B" ], "year": 2024, "source": "Internistische Praxis. 2024; 67(3): 538-544. ", "category": 1, "document_type": 1, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206960-14047" ], "persons": [ "206960-106501", "206960-53009" ], "imported": "2024-01-26T18:01:35+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 206975, "title": "Update on histology and molecular pathology in PM.", "abstract": null, "authors": [ "Brcic, L" ], "year": 2024, "source": "4TH THORACIC CANCERS ACADEMY; JAN 19-20, 2024; Zagreb, CROATIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "206975-14020" ], "persons": [], "imported": "2024-01-28T15:03:32+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207033, "title": "Klinische Fälle Kalziumstoffwechsel", "abstract": null, "authors": [ "Pilz, S" ], "year": 2024, "source": "D.A.CH-Tagung der DGE, ÖGES und SGED; JAN 19-20, 2024; Altdorf, GERMANY (ONline). 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207033-14080" ], "persons": [ "207033-53344" ], "imported": "2024-01-29T10:39:41+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207034, "title": "Analyzing TP53 aberration mediated cytarabine resistance in isogenic AML cell lines and the contribution of mesenchymal stromal cells to resistance using in vitro co culture.", "abstract": "Acute myeloid leukemia (AML) refers to an aggressive variant of leukemia in which mutations in the hematopoietic stem cells (HSCs) of the bone marrow lead to disruption of the entire hematopoietic system. The tumor suppressor TP53 plays an important role in preventing tumor development. Mutations of the TP53 gene are very common in human cancers and are found in up to 50% of cases. In AML patients, TP53 mutations are less common and affect up to 10% of patients but are often associated with very poor prognosis in terms of long-term survival, lower cure rate and increased mortality. In addition, there is an association between TP53 mutations and an increased incidence of resistance to chemotherapeutic agents. Because chemotherapeutic agents cause cell damage, TP53 in its wild-type form stops the cell cycle and induces DNA repair mechanisms or, if it accumulates too much, controlled cell death (apoptosis). However, if TP53 is damaged, it may not be able to perform its functions properly and AML cells will not undergo apoptosis, leading to resistance to chemotherapeutic agents. Furthermore, bone marrow cells can increase the chemotherapy resistance of AML cells. Mesenchymal stromal cells (MSCs) are an important component of the bone marrow and form adipocytes, myocytes, chondroblasts, and osteoblasts. Through inflammatory processes, these MSCs can be altered in their gene expression so that they lose their actual tumor suppressive properties and can even contribute to and enhance the chemotherapy resistance of, for example, AML cells. We created a 2D co-culture cell model with isogenic AML cells, which harbor hotspot TP53 mutations in different allelic states (mono- and bi-allelic), with human MSC cell lines HS-5 and HS-27A to investigate the contribution of the two MSC cell lines to the chemotherapeutic resistance of AML cell lines. In addition, we investigated the effect of different TP53 mutations in different allelic states on chemotherapy resistance during long-term treatment with cytarabine. TP53 mutations were found to have a significant effect on chemotherapeutic resistance, and co-culturing AML and MSC cells significantly increased chemotherapeutic resistance. ", "authors": [ "Zöscher, F" ], "year": 2024, "source": " [ Diplomarbeit/Master Thesis (UNI) ] Universität Graz; 2024. pp.103. ", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2024-01-29T11:26:33+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 207041, "title": "The role of the archaeome: composition and function in human health and disease ", "abstract": null, "authors": [ "Moissl-Eichinger, C" ], "year": 2024, "source": "European Congress of Clinical Microbiology and Infectious Diseases; APR 15-18, 2023; Kopenhagen, DENMARK. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207041-14023" ], "persons": [ "207041-90021" ], "imported": "2024-01-29T13:42:47+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": true, "local_affiliation": true }, { "id": 207066, "title": "Disordered regions regulate the interaction between p53 and the mRNA export factor THOC4", "abstract": null, "authors": [ "Khanna, Y", "Bourgeois, B", "Pichler, M", "Madl, T" ], "year": 2024, "source": "NMR Winter Retreat of Protein-RNA Interactions 2024; JAN 21-25, 2024; Parpan, Switzerland. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207066-14012", "207066-14013", "207066-14085" ], "persons": [ "207066-91207", "207066-98222" ], "imported": "2024-01-29T17:31:42+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207104, "title": "Preliminary data on a low molecular-weight factor isolated from human plasma which blocks L-Type Ca2+ current in cardiomyocytes", "abstract": null, "authors": [ "Pelzmann, B", "Kager, G", "Lang", "P", "Zorn-Pauly, K", "Platzer, D", "Cvirn, G", "Podesser, B", "Hallström, S" ], "year": 2024, "source": "11th Cardiovascular Research Days 2024; JAN 11-13, 2024; Weissensee, Austria. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207104-14011", "207104-14012" ], "persons": [ "207104-50068", "207104-50119", "207104-50417", "207104-50615", "207104-50840", "207104-50969" ], "imported": "2024-01-30T12:29:39+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207243, "title": "Coenzyme A fueling with pantethine limits autoreactive T cell pathogenicity in experimental neuroinflammation", "abstract": null, "authors": [ "Angiari, S", "Carlucci, T", "Budui, SL", "Bach, SD", "Dusi, S", "Walter, J", "Ellmeier, E", "Schnabl, A", "Tafrali, C", "Demjaha, R", "Khalil, M", "Bordag, N", "Laudanna, C", "Rossi, B", "Constantin, C." ], "year": 2024, "source": "Harald von Boehmer Midwinter Conference 2024 “Advances in\r\nImmunobiology”; January 20-24, 2024; Seefeld in Tirol, AUSTRIA. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207243-14014", "207243-14047", "207243-14051" ], "persons": [ "207243-107391", "207243-110988", "207243-115501", "207243-118907", "207243-119892", "207243-57435", "207243-87663", "207243-111610" ], "imported": "2024-01-30T17:28:44+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": true, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207252, "title": "Is single stage revision an acceptable way to treat PJI in oncology and when should it be used?", "abstract": null, "authors": [ "Smolle, MA", "Hauer, G", "Andreou, D", "Leithner, A" ], "year": 2024, "source": "Proceedings of the Birmingham Orthopaedic Oncology Meeting (BOOM) . 2024; 150-153.-Birmingham Orthopaedic Oncology Meeting (BOOM) ; JAN 29-30, 2024; Birmingham, UK. ", "category": 2, "document_type": 27, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207252-14052" ], "persons": [ "207252-101863", "207252-115078", "207252-53237", "207252-95171" ], "imported": "2024-01-30T21:31:06+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207253, "title": "How long should antibiotics be administered following a single stage treatment of PJI?", "abstract": null, "authors": [ "Smolle, MA", "Hauer, G", "Andreou, D", "Leithner, A" ], "year": 2024, "source": "Proceedings of the Birmingham Orthopaedic Oncology Meeting (BOOM) . 2024; 155-157.-Birmingham Orthopaedic Oncology Meeting (BOOM) ; JAN 29-30, 2024; Birmingham, UK. ", "category": 2, "document_type": 27, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207253-14052" ], "persons": [ "207253-101863", "207253-115078", "207253-53237", "207253-95171" ], "imported": "2024-01-30T21:33:01+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 207255, "title": "HRS vs. non-HRS Nierenversagen und Nierenersatz-Therapie", "abstract": null, "authors": [ "Tatscher, E" ], "year": 2024, "source": "ICU@Liver; JAN 13, 2024; Vienna, AUSTRIA. 2024. ", "category": 20, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "207255-14081" ], "persons": [ "207255-66467" ], "imported": "2024-01-31T09:27:37+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 207267, "title": "On the potential morpho-mechanical link between the gluteus maximus and pelvic floor tissues", "abstract": "Stress urinary incontinence is a condition that affects not only elderly females but also young female athletes performing in high-impact sports like volleyball and trampolining. Repetitive jumping seems to be an aggravating factor. In general, lax vaginal tissues and weakened supporting structures can lead to stress and urge incontinence. However, the underlying pathophysiology remains incompletely understood, particularly concerning the impact of the surrounding buttock tissues, including the gluteus maximus muscle. The study aimed to investigate the morpho-mechanical relationship between the gluteus maximus and the female pelvic floor. \r\nThe study involved the dissection of 25 pelves from Thiel-embalmed female cadavers while in a supine position. The mechanical properties of tissue strands connecting the gluteus maximus to the urogenital diaphragm were assessed in 20 specimens. Plastinates were also evaluated to confirm the dissection findings. In total, data were collected from 49 hemipelves. \r\nThe investigation revealed that the fascia of the gluteus maximus extends to the subcutaneous tissue, the fascia of the external anal sphincter, the fascia of the internal obturator, and the fascia of the urogenital diaphragm. This link to the internal obturator and the urogenital diaphragm can be regarded as an extension of the gluteus maximus fascia. The connection between the gluteus maximus and the urogenital diaphragm was able to withstand an average force of 23.6 ± 17.3 N. Cramér φ analyses demonstrated consistent connections of the fasciae linking the gluteus maximus with its surroundings in both the horizontal and sagittal planes.\r\nIn conclusion, the study showed that the gluteus maximus is closely linked to the pelvic floor through connective tissue strands and fascial continuations covering the adjacent muscles. While previous research has suggested that the gluteus maximus supports urinary continence, the here-described morpho-mechanical link suggests that it may potentially also play a role in urinary stress incontinence. Future research that combines clinical imaging with in-situ testing may provide additional insights into the clinical implications of these findings.", "authors": [ "Siess, M" ], "year": 2024, "source": "Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2024. pp. 67", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2024-01-31T09:54:14+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Medizinische Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 207270, "title": "Stärkung von Medication Adherence bei Patient*innen nach einem Myokardinfarkt - ein Scoping Review", "abstract": "Einleitung: Im Jahr 2021 erlitten in Österreich 16.080 Personen einen Myokardinfarkt und 4.301 Menschen starben daran. Die Medication Nonadherence nach einem Myokardinfarkt steht im Zusammenhang mit schwerwiegenden kardiovaskulären Ereignissen, einem verlängerten Krankenhausaufenthalt und einem erhöhten Mortalitätsrisiko. Pflegepersonen spielen aufgrund ihrer aufklärenden Funktion und ihrem häufigen Kontakt zu Patient*innen eine wichtige Rolle in der Stärkung der Medication Adherence.\r\nZiel: Das Ziel dieser Masterarbeit ist es aufzuzeigen, welche Interventionen es gibt, um Medication Adherence bei Patient*innen nach einem Myokardinfarkt zu stärken.\r\nMethode: Als Forschungsdesign wurde ein Scoping Review gewählt, um die Forschungsfrage zu beantworten. Eine systematische Literaturrecherche wurde von Mai bis Juni 2023 in den Datenbanken Pubmed, CINAHL und Ovid durchgeführt. Diese wurde durch eine Handsuche in Google Scholar ergänzt. Der Inhalt der identifizierten Studien wurde extrahiert und anschließend narrativ sowie tabellarisch dargestellt.\r\nErgebnisse: Durch die systematische Literaturrecherche konnten 25 Studien inkludiert werden. Die Resultate zeigten unterschiedliche Interventionen, die von Pflegepersonen, Pharmazeut*innen, Ärzt*innen oder einem multidisziplinären Team durchgeführt wurden. Die am häufigsten beschriebene Intervention, war die Aufklärung und Beratung der Patient*innen über die Wichtigkeit der Medikamenteneinnahme, die Wirkung und Nebenwirkungen der Medikamente und die eigene Erkrankung. In beinahe allen Studien mit dieser Intervention konnte eine signifikante Verbesserung der Medication Adherence aufgezeigt werden. Andere Studien untersuchten die Anwendung von Hilfsmittel zur Erinnerung an die Medikamenteneinnahme, ein WeChat Kommunikationsprogramm, frühzeitige Termine für Kontrolluntersuchungen, individuelle Zeit- und Interventionspläne, Methoden zur Stressreduktion, Verlängerung des Medikamentenrezepts oder Rehabilitationsmaßnahmen, mit dem Ziel die Medication Adherence zu verbessern.\r\nSchlussfolgerung: Die Aufklärung und Beratung von Patient*innen sind wirksame Maßnahmen, um die Medication Adherence nach einem Myokardinfarkt zu stärken. Wichtig hierbei ist es, auf die individuellen Bedürfnisse der Patient*innen einzugehen und die Angehörigen nach Zustimmung der Patient*innen als Ressource miteinzubeziehen.", "authors": [ "Tuppinger, H" ], "year": 2024, "source": "Masterstudium; Pflegewissenschaft; [ Masterarbeit ] Medizinische Universität Graz; 2024. pp. 78", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2024-01-31T09:54:14+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Medizinische Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 207272, "title": "Peripheral fractional tissue oxygen extraction and infection in term and preterm neonates: a prospective pilot observational study", "abstract": "Introduction\r\nPeripheral muscle oxygenation enables early recognition of microcircular dysfunction in cases of infection/inflammation and/or sepsis. Peripheral fractional tissue oxygen extraction (pFTOE) represents the relative extraction from arterial to venous compartment, which provides information about oxygen consumption and oxygen delivery to tissue. Primary aim of the present study was to investigate, whether pFTOE measured within the first six hours after birth differs in term and preterm neonates, with laboratory signs of infection and without infection. \r\n\r\nMethods\r\nThis study was performed as a prospective observational study performed at the Division of Neonatology Graz. Term and preterm neonates ≥30 weeks of gestational age with respiratory distress, admission to the NICU and age < 6 hours were included in the present study. Within the first six hours after birth, peripheral and cerebral NIRS measurements, performed by five short (re-)applications on the right forearm and on the left forehead, respectively, were conducted. Routine monitoring of arterial oxygen saturation (SpO2), heart rate (HR), mean arterial blood pressure (MABP) were documented in the time frame of NIRS measurements. pFTOE was calculated by the formula using peripheral tissue oxygenation index (pTOI) and SpO2: pFTOE = (SpO2-pTOI)/SpO2. Routine blood samples, including C- reactive protein, leukocytes and IT-ratio during the first 48 hours after birth were collected. Neonates with signs of infection, defined as CRP >10mg/l, leukocytes <6000/µl or >30000/µl, IT ratio >0.2 and/or positive blood culture were stratified to the infection group. Those neonates with inauspicious laboratory parameter were stratified to the no-infection group. Neonates of the infection group were compared to the no-infection group. Term and preterm neonates were analysed separately. \r\n\r\nResults\r\nA total of 80 neonates, 32 term neonates (infection n=15, no-infection group n=17) and 48 preterm neonates (n=6, n=42), were included in the present study. Gestational age and birth weight were 39.6 ±1.7 weeks and 3543 ±615 grams and 38.5 ±1.4 and 3221 ±592 grams in term neonates of the infection group and of the no-infection group, respectively. There were no differences in pFTOE 0.229 ±0.064 in the infection group and 0.235 ±0.032 in the no-infection group (p=0.293). \r\nIn preterm neonates, gestational age and birth weight were 34.8 ±1.7 weeks and 2476 ±720 grams and 34.3 ±1.6 and 2284 ±474 grams in the infection group and in the no-infection group, respectively. There were no differences in pFTOE 0.235 ±0.050 in the infection group and 0.224 ±0.051 in the no-infection group (p=0.306). \r\n\r\nConclusion\r\nIn the present study, in term and preterm neonates with infection no difference in pFTOE measured by five short reapplications within the first six hours were observed compared to neonates without infection. Nevertheless, pFTOE as an early marker for microcirculatory dysfunction is still of interest in neonates with respiratory distress symptoms within the first hours after birth.", "authors": [ "Wolfsberger, C" ], "year": 2024, "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2024. pp. 96", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [ "207272-82050" ], "imported": "2024-01-31T09:54:14+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Medizinische Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 207274, "title": "An ex vivo organotypic rat femur slice culture – A novel tool for the investigation of bone regeneration and postnatal endochondral development", "abstract": "Postnatal longitudinal bone growth primarily occurs within the growth plate (GP) through the proliferation and osteogenic differentiation of chondrocytes via endochondral ossification. When changes in the GP organization occur due to injuries, illness, or as a result of therapy, this can lead to significant complications concerning the skeletal development. Regenerative processes following sustained injury and illness that diverge from restoring the original state can have significant negative complications such as premature closure of the GP or growth arrest resulting in limb shortening and/or angulation deformity. Currently, no preventative biological treatment is available for the GP pathological processes. One reason is the still no fully understood pathological regeneration mechanism, which leads to the growth-related issues. The lack of new, easy-to-handle research models that allow real-time investigation of the pathological regeneration process is still missing. \r\nIn this dissertation, I modified an ex vivo femur organotypic model (OTC) to investigated pathological regeneration processes following 1) GP injury similar to Salter Harris III and IV and 2) particle irradiation with proton or carbon ions (C-ions) at the MedAustron facilities. I utilized a 300 µm thick OTC and exposed the culture to the two experimental conditions, respectively, with subsequent in vitro cultivation for up to 15 days. I conducted electron microscopy, gene expression analysis, live/dead staining, histological examinations, and immunohistochemistry and analyzed key markers of endochondral ossification.\r\nRegarding the GPI investigation, we observed regeneration processes coupled with trauma-induced alteration of structural architecture and organization, as well as a pronounced impairment of chondrocyte maturation with a preference for chondrogenesis over osteogenesis within the ex vivo organotypic GPI model. Moreover, following PT, pathological regeneration processes indicated an initial loss of proliferating chondrocytes with the formation of chondrocyte clusters, reduced osteogenesis and chondrogenesis coupled with a disruption in extracellular matrix (ECM) maturation/composition. \r\nIn both studies, the results obtained from the ex vivo femur organotypic model are comparable to the in vivo situation, making this new bone development and regeneration model a powerfool tool to further advance the scientific knowledge.", "authors": [ "Etschmaier, V" ], "year": 2024, "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2024. pp. 144", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2024-01-31T09:54:14+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Medizinische Universität Graz", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false } ] }