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GET /v1/research/publication/?format=api&offset=149820&ordering=impactfactor
{ "count": 157555, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=149840&ordering=impactfactor", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=149800&ordering=impactfactor", "results": [ { "id": 194800, "title": "Neugeborenenversorgung.", "abstract": null, "authors": [ "Schwaberger, B", "Martensen, J" ], "year": 2022, "source": "Workshop für Ärzte & Ärztinnen am 10. Kongress der Arbeitsgemeinschaft für Notfallmedizin (AGN); APR 21-23, 2022; Graz, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194800-14094" ], "persons": [ "194800-100059", "194800-79516" ], "imported": "2022-04-27T11:58:40+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 210808, "title": "A new approach for detecting prosopagnosia in children.", "abstract": null, "authors": [ "Avian, A" ], "year": 2024, "source": "IMPS - Annual meeting of the Psychometric Society; JUL 16-19, 2024; Prag, Czech Republic. 2024. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "210808-14026" ], "persons": [ "210808-67207" ], "imported": "2024-08-19T12:13:31+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 180937, "title": "The Effect of Glucagon Like Peptide-1 Receptor Agonism in T Cell Mediated Diseases: A Thorough Study of the Case of Nephrotoxic Serum Nephritis", "abstract": "Background: Recent randomized controlled trials have shown that glucagon like peptide (GLP)-1 analogues like liraglutide can improve kidney function in patients with type 2 diabetes mellitus. Though the mechanism of action of this effect is not yet clear, a possibility is the anti-inflammatory potential of GLP-1 receptor (Glp1r) agonism. Thus, we aimed to test the anti-inflammatory capacity of Glp1r agonism in a non-diabetic, T cell mediated murine model of nephrotoxic serum nephritis (NTS). \n\nMethods: NTS was induced in Glp1r-/- mice and littermate controls. Furthermore, liraglutide treatment in NTS was tested in C57BL/6J mice. In vitro, murine T cells were stimulated in the presence of liraglutide or vehicle.\n\nResults: Glp1r-/- mice displayed increased renal infiltration of neutrophils and T cells after induction of NTS as compared to littermate controls. In parallel, splenocyte proliferation and Th1 cytokine transcription were increased in spleen and lymph nodes of Glp1r-/- mice after NTS induction. Nevertheless, no difference in renal outcomes such as albuminuria and histological changes was detected between the two groups. In contrast, liraglutide treatment significantly improved the renal outcome of NTS in C57BL/6 mice as reflected by decreased albuminuria and histological changes. This was accompanied by a significant decrease in the renal infiltration of T cells and macrophages and a decrease in renal Th1 cytokine transcription. Renal beneficial effects of liraglutide were mediated via the Glp1r since liraglutide failed to protect Glp1r-/- mice from NTS. In vitro, T cells stimulated in the presence of liraglutide showed decreased proliferation and IL-6 production as compared to vehicle. In addition, liraglutide blocked glycolysis and decreased the expression of Glut1 mRNA in T cells.\n\nConclusion: Our data support the hypothesis that Glp1r agonism has anti-inflammatory potential thereby protecting mice from a T cell dependent glomerulonephritis model, possibly by inhibiting T cell proliferation and interacting with their metabolic program. Thus, Glp1r agonism by liraglutide might also be an attractive new therapeutic tool in the treatment of other T cell mediated diseases.\n", "authors": [ "Moschovaki Filippidou, F" ], "year": 2019, "source": "PhD-Studium (Doctor of Philosophy); Humanmedizin; [ Dissertation ] Graz Medical University; 2019. pp.113", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2020-02-14T09:54:57+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Graz Medical University", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 194803, "title": "Hymenoptera venom allergy update: a global perspective\r\n", "abstract": null, "authors": [ "Sturm, GJ" ], "year": 2022, "source": "Joint Conference World Allergy Organization (WAO) and British Society for Allergy & Clinical Immunology (BSACI); APRIL 25-27, 2022; Edinburgh, United Kingdom. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194803-14047" ], "persons": [ "194803-87717" ], "imported": "2022-04-27T23:48:43+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194804, "title": "Venom immunotherapy: contraindications and risk factors for adverse events", "abstract": null, "authors": [ "Sturm, GJ" ], "year": 2022, "source": "Venom Forum Prague\r\n; MARCH 18-19, 2022; Prague, Czech Republic. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194804-14047" ], "persons": [ "194804-87717" ], "imported": "2022-04-28T00:01:35+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 180936, "title": "Immuntherapeutika in der Onkologie.", "abstract": "Hintergrund\nAuf dem Gebiet der Immuntherapie gegen Krebs hat es in den letzten Jahren zahlreiche Entwicklungen und Fortschritte gegeben. Sich das körpereigene Immunsystem im Kampf gegen Krebs zu Nutze zu machen, birgt aber die Gefahr, ungewollt auch gesunde Zellen in die Schusslinie zu bringen und im schlimmsten Fall eine Autoimmunerkrankung zu provozieren. Immuntherapie gegen Krebs ist also eine schmale Gratwanderung, die seit vielen Jahren Gegenstand intensiver Forschung ist. Da Krebserkrankungen in den meisten Industriestaaten zu den häufigsten Todesursachen zählen, gilt die Immunonkologie als großer Hoffnungsträger der modernen Medizin.\n\nMethoden\nZiel dieser Arbeit ist es, einen strukturierten Überblick über das aktuelle und sehr umfassende Thema der Immuntherapie in der Onkologie zu geben. Dafür wurde eine systematische Literaturrecherche in Lehrbüchern, Fachzeitschriften, der medizinischen Literaturdatenbank „PubMed“ sowie verschiedenen Websites durchgeführt.\n\nSchlussfolgerung\nEin besseres Verständnis der Interaktion zwischen Tumor und Immunsystem hat wesentlich zur Entwicklung neuer Therapiestrategien beigetragen. Die neuen Therapieansätze sind zwar vielversprechend, aber auch mit beträchtlichen Risiken verbunden. Während Immuntherapeutika bei manchen Tumoren schon seit Jahren einen festen Platz in den Therapielinien eingenommen haben, gibt es für andere bisher noch keine zugelassenen Wirkstoffe. Zudem profitieren nicht alle Patientinnen und Patienten von den bisher zugelassenen Therapeutika. Die Gründe hierfür sind größtenteils unbekannt. Trotz großer Fortschritte in den letzten Jahren sind noch längst nicht alle Fragen geklärt, weshalb in kaum einem anderen Bereich der Medizin so viel geforscht wird wie in der Immunonkologie.", "authors": [ "Rohrer, I" ], "year": 2020, "source": "Humanmedizin; [ Diplomarbeit ] Graz Medical University; 2020. pp. 69", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2020-02-14T09:54:57+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Graz Medical University", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 194807, "title": "Let this fracture be the last", "abstract": null, "authors": [ "Puchwein, P", "Fahrleitner-Pammer A" ], "year": 2022, "source": "Netzwerktreffen Traumazentren Steiermark\r\n; APR 26, 2022; Graz, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194807-14052", "194807-14080" ], "persons": [ "194807-51063", "194807-62925" ], "imported": "2022-04-28T18:09:24+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194808, "title": "HAE-Update", "abstract": null, "authors": [ "Schöffl, C" ], "year": 2022, "source": "Round Table for Residents; APR 28, 2022; Graz, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194808-14047" ], "persons": [ "194808-95463" ], "imported": "2022-04-28T23:38:52+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194809, "title": "COVID-19 Vakzinierung – Immunstatus und Outcome", "abstract": null, "authors": [ "Stradner, MH" ], "year": 2022, "source": "Wiener Medizinische Wochenschrift\r\nSkriptum. 2022; ", "category": 1, "document_type": 3, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194809-14086" ], "persons": [ "194809-53560" ], "imported": "2022-04-29T10:57:35+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194810, "title": "The role of ATGL in intestinal and systemic lipid homeostasis", "abstract": null, "authors": [ "Korbelius, M", "Vujic, N", "Kuentzel, KB", "Rainer, S", "Kratky, D" ], "year": 2022, "source": "8th International Graz Symposium on Lipid and Membrane Biology; APR 21-23, 2022; Graz, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194810-14013" ], "persons": [ "194810-50245", "194810-51904", "194810-75396", "194810-76131" ], "imported": "2022-04-29T11:32:49+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194811, "title": "Das kritisch kranke Kind.", "abstract": null, "authors": [ "Schwaberger, B" ], "year": 2022, "source": "\"NEF Jour Fixe 04/2022\" des Notarztarztstützpunktes Deutschlandsberg; APR 28, 2022; Deutschlandsberg, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194811-14094" ], "persons": [ "194811-79516" ], "imported": "2022-04-29T12:01:48+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194812, "title": "MRI Safety - Theoretical Considerations and Practical Issues.", "abstract": null, "authors": [ "Reishofer, G" ], "year": 2022, "source": "Advanced MRI from head to toe. (AMRI 2022); APR 27-30, 2022; Graz, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194812-14054" ], "persons": [ "194812-57389" ], "imported": "2022-04-29T12:58:22+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194813, "title": "Artificial Intelligence: Applications in Radiology.", "abstract": null, "authors": [ "Reishofer, G" ], "year": 2022, "source": "Advanced MRI from head to toe. (AMRI2022); APR 27-30; Graz, AUSTRIA. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194813-14054" ], "persons": [ "194813-57389" ], "imported": "2022-04-29T13:02:13+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194814, "title": "Aktuelles zu Impfungen", "abstract": null, "authors": [ "Grisold, A" ], "year": 2022, "source": "Aktion \"Saubere Hände\"; 28.April 2022; Pörtschach, Österreich. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194814-14023" ], "persons": [ "194814-51863" ], "imported": "2022-04-29T14:32:16+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194815, "title": "Impfungen im Erwachsenenalter", "abstract": null, "authors": [ "Grisold, A" ], "year": 2022, "source": "Fortbildung im Bezirk; APR 28, 2022; 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194815-14023" ], "persons": [ "194815-51863" ], "imported": "2022-04-29T14:36:50+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": null, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": true, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194816, "title": "Prä- und Probiotika", "abstract": null, "authors": [ "Stadlbauer, V" ], "year": 2022, "source": "Ernährungsmedizin ; APR 23, 2022; Wien. 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194816-14081" ], "persons": [ "194816-50989" ], "imported": "2022-04-30T08:29:30+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": true, "local_affiliation": true }, { "id": 194817, "title": "Differentialdiagnose der Hepatosplenomegalie", "abstract": null, "authors": [ "Stadlbauer, V" ], "year": 2022, "source": "; APR 29, 2022; 2022. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194817-14081" ], "persons": [ "194817-50989" ], "imported": "2022-04-30T08:30:55+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 180935, "title": "Clinical relevance of mildly elevated pulmonary arterial pressure", "abstract": "Background and aims: Mean pulmonary arterial pressure (mPAP) is 14.0 ± 3.3mmHg (mean ± SD) under physiological conditions. As we initiated our study, the definition of pulmonary hypertension (PH) was an elevation of mPAP ≥ 25 mmHg. The clinical relevance of mildly elevated mPAP above 20 mmHg but below 25 mmHg was unclear. Accordingly, we aimed to assess the association of resting mPAP with all-cause mortality in a retrospective and a prospective cohort of patients with unexplained dyspnea and/or at risk of PH with special focus on patients not fulfilling the former hemodynamic criteria of PH. \nMethods: Prognostic cut-offs specific for our collective were first calculated by using regression tree (CART) analysis. In a second step mPAP cut-offs from the literature were used: lower-normal mPAP (≤ mean+ 1st SD), upper-normal mPAP (between mean + 1st SD and mean + 2nd SD), borderline (between mean + 2nd SD and 25 mmHg), and manifest PH (≥ 25 mmHg). We performed univariate and multivariate survival analysis adjusted for age and comorbidities.\nResults: Overall 547 patients were enrolled with 153 patients (26%) prospectively recruited. All patients underwent invasive assessment of pulmonary hemodynamics by means of right heart catheterization (RHC). N = 137, 56, 64 and 290 presented with lower-normal, upper-normal, borderline mPAP and manifest PH, respectively. The CART analysis on mPAP revealed three prognostic groups, mPAP < 17mmHg, 17 - 26 mmHg, and >26mmHg, with significantly decreasing survival. The univariate analysis based on thresholds from the literature showed that upper-normal, borderline mPAP and manifest PH were significantly associated with poor survival, compared to lower-normal mPAP. However, patients with mildly elevated pulmonary pressure were significantly older and had more cardiopulmonary comorbidities. In addition, they presented with lower exercise capacity and higher frequencies of exercise PH. In the multivariate model, corrected for age and comorbidities, only borderline mPAP [HR: 2.37, 95% CI: 1.14 - 4.97 (p = 0.022)] and manifest PH [HR: 5.05, 95% CI: 2.79 - 9.12 (p < 0.001)] were significantly associated with poor survival. \nConclusion: In a combined retro- and prospective cohort at risk for PH and/or with unexplained dyspnea, unbiased CART analysis revealed prognostic cut-offs at a resting mPAP of 17 mmHg and 26mmHg. A mPAP between 20 mmHg and 25 mmHg represents an independent predictor of poor survival. Based on our results together with findings from other studies the definition for pulmonary hypertension was changed to mPAP > 20 mmHg at the 6th World Symposium on Pulmonary Hypertension in Nice, 2018.", "authors": [ "Douschan, P" ], "year": 2019, "source": "Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Graz Medical University; 2019. pp. 93", "category": 5, "document_type": 16, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [], "persons": [], "imported": "2020-02-14T09:54:57+01:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Graz Medical University", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 194819, "title": "Risk factors and impact of intraocular lens characteristics on intraocular lens dislocation after cataract surgery – a population study.", "abstract": null, "authors": [ "Gabriel, M", "Pregartner, G", "Hirnschall, N", "Falb, T", "Sommer, M", "Findl, O", "Wedrich, A", "Mayer-Xanthaki, CF", "" ], "year": 2022, "source": "European Society of Cataract and Refractive Surgeons. 2022; -26th ESCRS Winter Meeting; FEB 18-20, 2022; Online. ", "category": 2, "document_type": 22, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194819-14026", "194819-14043" ], "persons": [ "194819-104484", "194819-53938", "194819-61522", "194819-84730", "194819-91877" ], "imported": "2022-04-30T14:21:43+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 194820, "title": "Mapping choroidal thickness in health and disease using three-dimensional 1060-nm optical coherence tomography. ", "abstract": null, "authors": [ "Gabriel, M", "Kruger, R", "Shams-Mafi, F", "Hermann, B", "Zabihian, B", "Schmetterer, L", "Drexler, W", "Ansari-Shahrezaei, S", "Binder, S", "Esmaeelpour, M", "" ], "year": 2019, "source": "60. Jahrestagung der ÖOG. 2019; -ÖOG; MAY 30 - JUN 1, 2019; Schladming. ", "category": 2, "document_type": 9, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "194820-14043" ], "persons": [ "194820-104484" ], "imported": "2022-04-30T15:37:06+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": true, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false } ] }