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GET /v1/research/publication/?format=api&offset=149720&ordering=impactfactor
{ "count": 157573, "next": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=149740&ordering=impactfactor", "previous": "https://api-test.medunigraz.at/v1/research/publication/?format=api&limit=20&offset=149700&ordering=impactfactor", "results": [ { "id": 196595, "title": "Influence of Sclerostin on Lung Vasculature.", "abstract": "Sclerostin, a secreted glycoprotein, is mainly expressed in osteocytes and a well-known negative regulator of bone formation. Recently there has been an increasing number of studies indicating that sclerostin also plays a major role in pulmonary vasculature. These findings are vitally important for scientific research because further understanding of the role of sclerostin could help the development of possible therapies and medication for illnesses like idiopathic pulmonary arterial hypertension (IPAH).\r\nThe hypothesis of this thesis is that impaired expression of sclerostin in pulmonary vasculature affects the function of lung vascular cells contributing to the development of IPAH. In order to verify our hypothesis, it was necessary to localize the expression of sclerostin, to determine differences in the expression of sclerostin between IPAH and healthy pulmonary arteries (PA) and to analyze the effect of sclerostin on pulmonary vascular cells, specifically on human pulmonary artery smooth muscle cells (hPASMC) and human pulmonary artery endothelial cells (hPAEC).\r\nIt could be proved, that sclerostin is localized in PA, specifically in hPAEC as well as in hPASMC. Differential expression analysis emphasizes that sclerostin level is increased in PA of IPAH patients compared to healthy donors. HPASMC isolated from donor and IPAH PA do not show significant increase of sclerostin, suggesting that the upregulation observed in IPAH PA compared to donors is most probably caused by an upregulation of sclerostin in hPAEC. As hPAEC possess the receptor for sclerostin, we investigated the possible effect of sclerostin on hPAEC. We observed protective effects of sclerostin pre-treatment on thrombin mediated barrier dysfunction. This effect was not mediated by an influence of sclerostin on VE-Cadherin but rather by an influence on calcium handling. Indeed, sclerostin affects calcium homeostasis of hPAEC by increasing calcium influx and decreasing calcium store depletion. We could also show that sclerostin could have an effect on metabolism of hPAEC, increasing their mitochondrial respiration.\r\nIn conclusion, these results suggest that sclerostin could be a protective factor for hPAEC during the development of IPAH. Hence, sclerostin could be of major importance for further understanding of molecular mechanisms underlying IPAH. Additional experiments are needed to further elucidate the exact role of sclerostin and possibly make valid therapeutic implications.", "authors": [ "Peinsipp, P" ], "year": 2022, "source": " [ Diplomarbeit/Master Thesis (UNI) ] Graz University of Technology; 2022. pp.84. ", "category": 5, "document_type": 15, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196595-14010" ], "persons": [ "196595-73404" ], "imported": "2022-07-22T11:19:21+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": "Graz University of Technology", "country": "40", "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196596, "title": "Technisierung der Pflege. 4. Goldegger Dialogforum Mensch und Endlichkeit (Bioethik in Wissenschaft und Gesellschaft).", "abstract": null, "authors": null, "year": 2022, "source": "Stronegger, WJ; Platzer, J. editor(s). 15: Nomos; 2022. (ISBN: 978-3-8487-8492-9) ", "category": 7, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196596-14024", "196596-14058" ], "persons": [ "196596-51741", "196596-60382" ], "imported": "2022-07-22T12:19:24+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 196597, "title": "Angewandte wissenschaftliche Weiterbildung im Bereich der klinischen Embryologie", "abstract": null, "authors": [ "Wenninger, J", "Petek, T, Ebner, T", "Schenk, M" ], "year": 2016, "source": " In: Egger,R; Bauer, M; editors(s). Bildungspartnerin Universität: Tertiäre Weiterbildung für eine erfolgreiche Zukunft . Wiesbaden, Germany: Springer VS; p. 125-141. 2016(ISBN: 9783658150129) ", "category": 6, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196597-14021", "196597-14058" ], "persons": [ "196597-51996", "196597-65727" ], "imported": "2022-07-22T13:42:37+02:00", "journal": null, "issn": null, "collection_publisher": "Egger,R; Bauer, M;", "collection_title": "Bildungspartnerin Universität: Tertiäre Weiterbildung für eine erfolgreiche Zukunft ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 196598, "title": "Medizin und säkulare Gesellschaft. Die Utopie totaler Gesundheit durch akzelerierte\r\nTechnologiekonvergenz. ", "abstract": null, "authors": [ "Stronegger, WJ" ], "year": 2022, "source": " In: Stronegger, WJ; Platzer, J; editors(s). Technisierung der Pflege. 4. Goldegger Dialogforum Mensch und Endlichkeit (Reihe Bioethik in Wissenschaft und Gesellschaft). 15: Baden-Baden: Nomos; p. 15-63. 2022(ISBN: 978-3-8487-8492-9) ", "category": 6, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196598-14024" ], "persons": [ "196598-51741" ], "imported": "2022-07-22T13:48:34+02:00", "journal": null, "issn": null, "collection_publisher": "Stronegger, WJ; Platzer, J;", "collection_title": "Technisierung der Pflege. 4. Goldegger Dialogforum Mensch und Endlichkeit (Reihe Bioethik in Wissenschaft und Gesellschaft)", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 196601, "title": "Lung function and co-morbidities.", "abstract": null, "authors": [ "Singer, F" ], "year": 2021, "source": "42. Jahrestagung der Deutschen Gesellschaft für Pneumologie (GPP); MAR 25-27, 2021; Hamburg, GERMANY. 2021. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196601-14095" ], "persons": [ "196601-113973" ], "imported": "2022-07-22T14:21:00+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196602, "title": "Lung function monitoring in CF - Update.", "abstract": null, "authors": [ "Singer, F" ], "year": 2020, "source": "44. Jahrestagung der Österreichischen Gesellschaft für Pneumologie (ÖGP); OCT 14-16,2020; Vienna, AUSTRIA. 2020. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196602-14095" ], "persons": [ "196602-113973" ], "imported": "2022-07-22T14:25:20+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196603, "title": "Treatment rational of BPD beyond infancy.", "abstract": null, "authors": [ "Singer, F" ], "year": 2019, "source": "41. Jahrestagung der Deutschen Gesellschaft für Pneumologie (GPP); Mar 13-16, 2019; München, GERMANY. 2019. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196603-14095" ], "persons": [ "196603-113973" ], "imported": "2022-07-22T14:30:09+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196604, "title": "CF evidence-based treatments.", "abstract": null, "authors": [ "Singer, F" ], "year": 2019, "source": "Annual Meeting of the Swiss Society of Pulmonology (SGP); MAY 9-10, 2019; Montreux, SWITZERLAND. 2019. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196604-14095" ], "persons": [ "196604-113973" ], "imported": "2022-07-22T14:41:58+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196605, "title": "Multiple-breath washout: ready for inclusion into registries.", "abstract": null, "authors": [ "Singer, F" ], "year": 2018, "source": "Annual Meeting of the ECFS Diagnostic Network Working Group; OCT 8-10, 2018; St. Gallen, Switzerland. 2018. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196605-14095" ], "persons": [ "196605-113973" ], "imported": "2022-07-22T15:11:42+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196606, "title": "Multiple-breath washout in CF - good tool or expensive toy.", "abstract": null, "authors": [ "Singer, F" ], "year": 2018, "source": "42. Jahrestagung de Österreichischen Gesellschaft für Pneumologie (ÖGP); OCT 18-20, 2018; Linz, AUSTRIA. 2018. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196606-14095" ], "persons": [ "196606-113973" ], "imported": "2022-07-22T15:21:27+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": false, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196607, "title": "CF-Therapy - screen and detect early.", "abstract": null, "authors": [ "Singer, F" ], "year": 2017, "source": "39. Jahrestagung der Deutschen Gesellschaft für Pneumologie (GPP); MAR 30 - APR 1, 2018; Essen, GERMANY. 2017. ", "category": 3, "document_type": null, "sci": null, "pubmed": null, "doi": null, "pmc": null, "organizations": [ "196607-14095" ], "persons": [ "196607-113973" ], "imported": "2022-07-22T15:46:43+02:00", "journal": null, "issn": null, "collection_publisher": null, "collection_title": null, "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": null, "conference_name": true, "conference_place": true, "conference_international": true, "scientific_event": true, "invited_lecture": true, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": false }, { "id": 196627, "title": "Comparison of non-invasive tear film break-up time assessed by keratography with conventional fluorescein tear film break-up time", "abstract": null, "authors": [ "Berisha, B", "Nepp, J", "Rabensteiner, DF", "Wagner, G", "Boldin, I", "Aminfar, H", "Horwath-Winter, J" ], "year": 2022, "source": "SPEKTRUM AUGENHEILKD. 2022; ", "category": 1, "document_type": 1, "sci": "ISI:000826789300001", "pubmed": null, "doi": "10.1007/s00717-022-00525-w", "pmc": null, "organizations": [ "196627-14043" ], "persons": [ "196627-53007-6", "196627-56837-6", "196627-84748-6" ], "imported": "2022-07-25T09:56:30+02:00", "journal": "SPEKTRUM AUGENHEILKD", "issn": "0930-4282", "collection_publisher": null, "collection_title": "SPEKTRUM DER AUGENHEILKUNDE; ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": false, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 196631, "title": "Adjuvant therapy of endometrial cancer", "abstract": null, "authors": [ "Mallmann, P", "Vordermark, D", "Feyer, P", "Hagen, V", "Hocht, S", "Niehoff, P", "Petru, E", "Zeimet, AG", "Micke, O", "Battista, MJ" ], "year": 2022, "source": "GYNAKOLOGIE. 2022; 55(7): 501-508. ", "category": 1, "document_type": 1, "sci": "ISI:000823302900006", "pubmed": null, "doi": "10.1007/s00129-022-04959-w", "pmc": null, "organizations": [ "196631-14063" ], "persons": [ "196631-51624-6" ], "imported": "2022-07-25T09:56:30+02:00", "journal": "GYNAKOLOGIE", "issn": "2731-7102", "collection_publisher": null, "collection_title": "GYNAKOLOGIE; ", "edition": null, "university": null, "country": null, "case_report": false, "impactfactor": null, "impactfactor_year": null, "impactfactor_norm": null, "impactfactor_norm_year": null, "impactfactor_norm_category": null, "impactfactor_norm_super": null, "impactfactor_norm_super_year": null, "impactfactor_norm_super_category": null, "citations": false, "conference_name": null, "conference_place": null, "conference_international": false, "scientific_event": false, "invited_lecture": false, "keynote_speaker": false, "selected_presentation": false, "biobank_use": false, "bmf_use": false, "zmf_use": false, "local_affiliation": true }, { "id": 196645, "title": "Opthalmologic Complications of Diabetes", "abstract": null, "authors": [ "Malle, O", "Wedrich, A" ], "year": 2022, "source": "AUST J CLIN ENDOCR M. 2022; 15(2): 53-55. 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